Jurnal Biologi Tropis
Vol. 23 No. 2 (2023): April-June

Anti-Stapylococcus Epidermidis of Methanolic Extracts from Some East Lombok Medicinal Plants

Dyke Gita Wirasisya (Universitas Mataram)
Amni Hamid (Universitas Mataram)
Muhamad Haikhal (Universitas Mataram)
Agriana Rosmalina Hidayati (Universitas Mataram)
Anggit Listyacahyani Sunarwidhi (Universitas Mataram)
Nisa Isneni Hanifa (Universitas Mataram)



Article Info

Publish Date
05 Mar 2023

Abstract

Wounds are structural and functional disruptions of the skin that occur as a result of an injury. Wound healing is a complex tissue repair or remodelling process in response to the injury. The most common factor that causes wounds not properly heal is infection. An infection develops when microorganisms enter the body, multiply, and trigger an immune reaction in the body. This study aims to determine the activity of Jatropha multifida L., Stachytarpheta jamaicensis (L.) Vahl, Centella asiatica (L.) Urb., Euphorbia pulcherrima Willd. ex Klotzsch, and Angelica keiskei (miq.) Koidz has long been used to treat and manage wounds in East Lombok. The plants were dried and macerated with methanol; excessed solvent was evaporated. Disc diffusions were used to determine the antibacterial activity of the plant extracts. All extracts were tested against Staphylococcus epidermidis, a common cause of wound infection. Statistically, the activity of Jatropha multifida (5;10 mg/mL), Stachytarpheta jamaicensis (10 mg/mL), Centella asiatica (10 mg/mL), Euphorbia pulcherrima (M) (5, 10 mg/mL), and Angelica keiskei (2,5; 5; 10 mg/mL) extracts were comparable with positive control. However, Angelica keiskei has a wider inhibition zone than other extracts. This discovery could be served as a basis for using plants to aid wound healing, especially to combat the interference bacteria. However, further research is needed to discover the active phytochemicals involved in the antibacterial and wound healing process.

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Journal Info

Abbrev

JBT

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

Description

Jurnal Biologi Tropis (ISSN Cetak 1411-9587 dan ISSN Online 2549-7863) diterbitkan mulai tahun 2000 dengan frekuensi 2 kali setahun oleh Program Studi Pendidikan Biologi PMIPA FKIP Universitas Mataram, berisi hasil penelitian dan ulasan Ilmiah dalam bidang Biologi ...