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Sunarwidhi, Anggit Listyacahyani
Universitas Mataram
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Uji Aktivitas Antibakteri Ekstrak Etanol Rumput Laut Cokelat (Sargassum cristaefolium) terhadap Staphylococcus epidermidis Harhara, Zanira Faisal; Suryani, Dewi; Sunarwidhi, Anggit Listyacahyani
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 2, No 2 (2021): JULI
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v2i2.5369

Abstract

ABSTRAKStaphylococcus epidermidis diketahui menyebabkan infeksi kulit oportunistik termasuk menyebabkan acne vulgaris. Pemilihan bahan alam rumput laut cokelat Sargassum cristaefolium diharapkan dapat digunakan sebagai alternatif baru terhadap tingginya angka resistensi bakteri akibat antibiotik. Tujuan penelitian ini adalah menentukan aktivitas antibakteri ekstrak etanol S.cristaefolium terhadap S.epidermidis. S.cristaefolium dikumpulkan dari pantai Batu Layar Lombok dan dimaserasi dengan etanol 96%. Penelitian ini kemudian mencakup pemberian konsentrasi ekstrak etanol S.cristaefolium (60%, 80% dan 100%) dan kontrol positif doksisiklin. Aktivitas antibakteri dari ekstrak diamati dengan metode difusi sumuran agar. Data yang diperoleh dianalisis statistik menggunakan uji parametrik One Way ANOVA. Hasil skrining fitokimia menunjukkan bahwa ekstrak etanol S.cristaefolium mengandung alkaloid, tanin, flavonoid, saponin, triterpenoid dan steroid serta memiliki daya hambat antibakteri pada konsentrasi 100% dengan diameter hambat 9.46 ± 1.60 termasuk katagori sedang, konsentrasi 80% dan 60% memiliki daya hambat lemah dengan diameter 2.63 ± 0.74 dan 1.96 ± 0.71. Bila dibandingkan kontrol positif, daya hambat ekstrak etanol S.cristaefolium memiliki hasil yang lebih rendah. Berdasarkan uji statistik One Way ANOVA, hasil aktivitas antibakteri ekstrak etanol S.cristaefolium berbeda signifikan dengan kontrol negative yang terlihat dari nilai p < 0.05. Kata kunci: Staphylococcus epidermidis; Sargassum cristaefolium; Aktivitas Antibakteri; Ekstrak etanol 96%; Zona hambatABSTRACTStaphylococcus epidermidis is known to cause opportunistic skin infections including acne. The selection of natural material such as brown seaweed Sargassum cristaefolium is expected to be used as a new alternative to high number of bacterial resistance due to antibiotics. The purpose of this study was to determine the antibacterial activity of the ethanolic extract of S.cristaefolium against S.epidermidis. S.cristaefolium collected from Batu Layar coast Lombok and macerated with 96% ethanol. This research  included the difference of any concentrations (60%, 80% and 100%) and doxycycline as positive control. The Antibacterial activity of the extract would be observed by agar well diffusion method. The data was then analyzed statistically using the One Way ANOVA parametric test. The results of phytochemical screening showed the ethanolic extract of S.cristaefolium contained alkaloid, tannin, flavonoid, saponin, triterpenoid and steroid. The antibacterial test showed that  at the concentration of 100% S.cristaefolium had 9.46 ± 1.60 of inhibition zone diameter and it was classified in to medium category. At the concentrations of 80% and 60% S.cristaefolium were classified in to weak category.  The diameters of the inhibition zone were 2.63 ± 0.74 and 1.96 ± 0.71. The research showed doxycycline as positive control has better result than any concentrations ethanol extract of S.cristaefolium. Based on the One Way ANOVA statistical test, the results of the antibacterial activity of S.cristaefolium ethanol extract were significantly different compared to the negative control, as seen from the p value < 0.05.Keywords: Staphylococcus epidermidis; Sargassum cristaefolium; Antibacterial activity; 96% ethanol extract; Zone of inhibition
Uji Aktivitas Antibakteri Ekstrak Etanol Rumput Laut Cokelat (Sargassum cristaefolium) terhadap Staphylococcus epidermidis Zanira Faisal Harhara; Dewi Suryani; Anggit Listyacahyani Sunarwidhi
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 2, No 2 (2021): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v2i2.5497

Abstract

ABSTRAKStaphylococcus epidermidis diketahui menyebabkan infeksi kulit oportunistik termasuk menyebabkan acne vulgaris. Pemilihan bahan alam rumput laut cokelat Sargassum cristaefolium diharapkan dapat digunakan sebagai alternatif baru terhadap tingginya angka resistensi bakteri akibat antibiotik. Tujuan penelitian ini adalah menentukan aktivitas antibakteri ekstrak etanol S.cristaefolium terhadap S.epidermidis. S.cristaefolium dikumpulkan dari pantai Batu Layar Lombok dan dimaserasi dengan etanol 96%. Penelitian ini kemudian mencakup pemberian konsentrasi ekstrak etanol S.cristaefolium (60%, 80% dan 100%) dan kontrol positif doksisiklin. Aktivitas antibakteri dari ekstrak diamati dengan metode difusi sumuran agar. Data yang diperoleh dianalisis statistik menggunakan uji parametrik One Way ANOVA. Hasil skrining fitokimia menunjukkan bahwa ekstrak etanol S.cristaefolium mengandung alkaloid, tanin, flavonoid, saponin, triterpenoid dan steroid serta memiliki daya hambat antibakteri pada konsentrasi 100% dengan diameter hambat 9.46 ± 1.60 termasuk katagori sedang, konsentrasi 80% dan 60% memiliki daya hambat lemah dengan diameter 2.63 ± 0.74 dan 1.96 ± 0.71. Bila dibandingkan kontrol positif, daya hambat ekstrak etanol S.cristaefolium memiliki hasil yang lebih rendah. Berdasarkan uji statistik One Way ANOVA, hasil aktivitas antibakteri ekstrak etanol S.cristaefolium berbeda signifikan dengan kontrol negative yang terlihat dari nilai p < 0.05.Kata kunci: Staphylococcus epidermidis; Sargassum cristaefolium;Aktivitas Antibakteri; Ekstrak etanol 96%; Zona hambatABSTRACTStaphylococcus epidermidis is known to cause opportunistic skin infections including acne. The selection of natural material such as brown seaweed Sargassum cristaefolium is expected to be used as a new alternative to high number of bacterial resistance due to antibiotics. The purpose of this study was to determine the antibacterial activity of the ethanolic extract of S.cristaefolium against S.epidermidis. S.cristaefolium collected from Batu Layar coast Lombok and macerated with 96% ethanol. This research  included the difference of any concentrations (60%, 80% and 100%) and doxycycline as positive control. The Antibacterial activity of the extract would be observed by agar well diffusion method. The data was then analyzed statistically using the One Way ANOVA parametric test. The results of phytochemical screening showed the ethanolic extract of S.cristaefolium contained alkaloid, tannin, flavonoid, saponin, triterpenoid and steroid. The antibacterial test showed that  at the concentration of 100% S.cristaefolium had 9.46 ± 1.60 of inhibition zone diameter and it was classified in to medium category. At the concentrations of 80% and 60% S.cristaefolium were classified in to weak category.  The diameters of the inhibition zone were 2.63 ± 0.74 and 1.96 ± 0.71. The research showed doxycycline as positive control has better result than any concentrations ethanol extract of S.cristaefolium. Based on the One Way ANOVA statistical test, the results of the antibacterial activity of S.cristaefolium ethanol extract were significantly different compared to the negative control, as seen from the p value < 0.05.Keyword: Staphylococcus epidermidis; Sargassum cristaefolium; Antibacterial activity; 96% ethanol extract; Zone of inhibition
PELATIHAN PEMBUATAN TABIR SURYA ANTI-UV PELINDUNG KULIT BERBASIS ALGAE COKLAT KEPADA PEMBUDIDAYA RUMPUT LAUT DI TELUK EKAS PADA MASA PANDEMI COVID-19 [TRAINING OF BROWN ALGAE ANTI-UV SUNSCREEN PROCESSING TECHNIQUE FOR SEAWEED FARMERS IN EKAS BAY DURING COVID-19 PANDEMIC] Anggit L. Sunarwidhi; Ni Wayan Riyani Martyasari; Eka Sunarwidhi Prasedya; Sri Widyastuti; Haji Sunarpi
Jurnal Sinergitas PKM & CSR Vol 5, No 1 (2021): April
Publisher : Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/jspc.v5i1.2950

Abstract

Exposure to ultraviolet (UV) light provides high effectiveness in inhibiting germs, bacteria and the Sars-Cov 2 virus that causes Corona Virus Disease-19 (COVID-19). However, due to the depletion of the ozone layer which acts to ward off short wave radiation, there is an increase of UV light radiation amount that reaches the earth's surface. As a result, human skin is exposed to UV radiation which can cause premature skin aging and even skin cancer. Researchers claim that brown algae contain anti-UV compounds that can absorb UV radiation. Therefore, it has been developed a skin protection cream based on brown algae seaweed that can protect human skin from exposure to UV radiation. This article reports on the introduction and training of how to produce anti-UV sunscreen for seaweed farmers who faces high intensity sun exposure on a daily basis. Participants were 20 person (wives and children of the farmers). In this training, video tutorial of making cream was played following with demonstration of making cream by the participants. After the training, it is hoped that the farmers wives and children will be able to produce this anti-UV sunscreen that was not for self-used to protection against UV radiation exposure, but could also for sale to increase the income of coastal communities during the COVID-19 pandemic. BAHASA INDONESIA ABSTRACT: Paparan sinar ultraviolet (UV) memberikan efektivitas yang tinggi dalam penghambatan kuman, bakteri hingga virus Sars-Cov 2 penyebab Corona Virus Disease-19 (COVID-19). Namun karena menipisnya lapisan ozon yang berperan menangkal radiasi gelombang pendek, maka radiasi akibat sinar UV sampai ke permukaan bumi. Akibatnya, kulit manusia terpapar radiasi UV yang dapat menyebabkan penuaan kulit secara dini dan bahkan kanker kulit. Para peneliti menyatakan bahwa algae coklat mengandung senyawa anti-UV yang dapat menyerap radiasi ultra violet. Karena itu, telah dikembangkan krim pelindung kulit berbasis rumput laut alga coklat yang dapat melindungi kulit manusia dari paparan radiasi UV. Artikel ini melaporkan pengenalan dan pelatihan cara pembuatan krim anti-UV kepada pembudidaya rumput laut yang sehari-hari harus berhadapan dengan terpaan matahari berintensitas tinggi. Hadir sejumlah 20 orang (para istri dan anak-anak pembudi daya). Dalam pelatihan ini diputarkan video tutorial membuat krim yang kemudian diikuti dengan demonstrasi membuat krim.  Setelah pelatihan, diharapkan para istri dan anak pembudidaya dapat memproduksi krim anti-UV yang tidak saja dapat digunakan sendiri sebagai perlindung terhadap paparan radiasi UV, melainkan juga dapat dijual untuk meningkatkan pendapatan masyarakat pesisir pada masa pandemi COVID-19. 
Effect of Solid and Liquid Extracts of Lombok Sargassum cristafolium on Growth and Yield of Rice Plants (Oryza sativa L.) Haji Sunarpi; Aluh Nikmatullah; Anggit L. Sunarwidhi; Yogi Ambana; Bq Tri Khairina Ilhami; Sri Widyastuti; Ari Hernawan; Eka Sunarwidhi Prasedya
Jurnal Biologi Tropis Vol. 20 No. 3 (2020): September - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v20i3.2048

Abstract

An exessive use of inorganic fertilizers in agriculture cultivation system causes many disadventages, such as increase cost production, reduce farmer’s income and soil fertility, and harm our environment. Therefore, it is needed to find out raw materials for development of organic biostimulant and biofertilizer inducing essential element absorption, growth and yield of plants, which are adaptive to our environment as well. Previous researchres reported that seaweed contained plant growth hormones and essential elements in liquid and solid extracts respectively. This article reports effect of solid and liquid extracts of Sargassum cristafolium on growth and yield of rice plants. The extracts were extracted according to modified procedure.. Solid extract (350 gr) of Sargassum cristafolium was mixed with soil (6650 gr) to become 7 kg soil media. Moreover, liquid extract (10%) of Sargassum cristafolium was sprayed to rice plants once a week during vegetative growth. The results shown that addition of 350 gr of solid extract to soil media increased growth (plant high, tiller number, shoot dry weight and root dry weight) and yield (penicle number and grain weight per plants) significantly compared with those of plants which were not supplied with solid extract. However, spraying liquid extract of Sargassum cristafolium did not affet significantly growth and yield of rice plants, even small change happen in growth and yield parameters of the rice plants supplied with solid extract. This indicates that solid extract is a potential source for development of biofertilizer which is adaptive to our environment to support sustainable agriculture system.
Phytochemical Screening of Decoction and Ethanolic Extract of Amomum dealbatum Roxb. Leaves Nisa Isneni Hanifa; Dyke Gita Wirasisya; Arinda Eka Muliani; Septia Budi Utami; Anggit Listyacahyani Sunarwidhi
Jurnal Biologi Tropis Vol. 21 No. 2 (2021): Mei - Agustus
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v21i2.2758

Abstract

Renggak (Amomum dealbatum Roxb.) is a species from the genus Amomum widely spread in Lombok. Traditionally, Amomum dealbatum Roxb. (renggak) is an antiseptic to treat rheumatism and arthritis. However, there was limited report of its phytochemical contents and biological activity of Amomum dealbatum Roxb. This study is preliminary research that aims to determine the phytochemical content of Amomum dealbatum Roxb. leaf decoction and its ethanolic extract. For this study, we used two different extraction methods. The fully powdered plant used for the successive extraction in the cold process for maceration methods was 800 g, and ethanols were used as solvents. We used a traditional receipt that utilized three fresh leaves in the decoction methods with 4,5 L of water as solvents. Phytochemical screening was carried out qualitatively by using the tube method with specific reagents for each compound. Important phytochemicals that were screened are flavonoids, alkaloids, tannins, saponins, steroids, and triterpenoids. Phytochemical screening from plant extract and decoction revealed the presence of flavonoids, alkaloids, and tannins. Triterpenoid was only detected on the extract, and none of the extract and decoction have saponins and steroids. Our finding provides information about secondary metabolites that present in Amomum dealbatum Roxb. These phytochemical findings are essential and might be useful as quality parameters and to predicts its biological activities.
Sosialisasi Pemanfaatan TOGA Dan Pembuatan Sabun Batang Alami (Sabun Aloe vera) Kepada Murid Yayasan Generasi Muslim Cendekia di Lombok Tengah, Indonesia Anggit L. Sunarwidhi; Dyke Gita Wirasisya; Nisa Isneni Hanifa
Jurnal Pengabdian Magister Pendidikan IPA Vol 3 No 2 (2020): .
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (299.61 KB) | DOI: 10.29303/jpmpi.v3i2.513

Abstract

Yayasan Generasi Muslim Cendekia (Yayasan GMC) terletak di desa Puyung, Lombok Tengah, Indonesia, dan telah memiliki fasilitas TOGA, namun selama ini tumbuh-tumbuhan obat yang terdapat di fasilitas tersebut tidak dimanfaatkan secara maksimal. Minimnya pengetahuan murid yayasan GMC yang menjadi alasan terjadinya hal tersebut. Oleh karena itu, dibutuhkan suatu program sosialisasi untuk mengedukasi murid di yayasan tersebut terkait hal ini. Selain itu, program sosialisasi juga melibatkan praktek pembuatan sediaan sederhana dengan pemanfaatan tanaman obat, yaitu pembuatan sabun batang alami dengan menggunakan aloe vera sebagai bahan utamanya. Sabun ini sangat bermanfaat terutama di masa pandemi COVID-19.Hasil evaluasi kegiatan menunjukkan bahwa kegiatan sosialisasi ini telah berjalan dengan baik, ditunjukkan dengan adanya peningkatan nilai posttest peserta yang signifikan dibandingkan dengan nilai pretest peserta. Melalui kegiatan ini, peserta mendapatkan pengetahuan terkait pemanfaatan TOGA maupun cara pembuatan sabun bantang alami (sabun aloe vera). Peserta menunjukkan antusias yang tinggi pada saat praktek maupun diskusi. Diharapkan ke depannya sosialisasi seperti ini dapat terus berlanjut, sehingga dapat terus meningkatkan kreatifitas murid-murid yayasan GMC dalam pemanfaatan TOGA, yang tidak hanya bermanfaat untuk kesehatan tetapi juga dapat berpotensi meningkatkan taraf ekonomi warga desa tersebut.
The Study of Potential Antiviral Compounds from Indonesian Medicinal Plants as Anti-COVID-19 with Molecular Docking Approach Baiq Ressa Puspita Rizma; Agus Dwi Ananto; Anggit Listyacahyani Sunarwidhi
Journal of Molecular Docking Vol 1 No 1 (2021): Journal of Molecular Docking
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.135 KB) | DOI: 10.33084/jmd.v1i1.2307

Abstract

Corona Virus Disease 2019 (COVID-19) is a new strain of coronavirus called SARS-CoV-2, which was identified in Wuhan, China, in December 2019. The rapid transmission of COVID-19 from human to human forced researchers to find a potent drug by setting aside the time-consuming traditional method in drug development. The molecular docking approach is one a reliable method to screening compound from chemical drug or by finding a compound from Indonesian herbal plants. The present study aimed to assess the potency of compounds from five medicinal plants as potential inhibitors of PLpro and 3CLpro from SARS-CoV-2 using molecular study. The molecular docking was performed using Protein-Ligand Ant System (PLANTS) to analyze the potential compounds by the docking score. Remdesivir triphosphate was used as a standard for the comparison of the test compounds. The docking score obtained from the docking of PLpro with native ligand, remdesivir triphosphate, curcumin, demethoxycurcumin, bisdemethoxycurcumin, luteolin, apigenin, quercetin, kaempferol, formononetin-7-O-glucuronide, andrographolide, and neoandrographolide were -111.441, -103.827, -103.609, -102.363, -100.27, -79.6655, -78.6901, -80.9337, -79.4686, -82.1124, -79.1789, and -97.2452, respectively. Meanwhile, docking score with 3CLpro for the same ligand were -64.0074, -86.1811, -81.428, -87.1625, -78.2899, -73.4345, -70.3368, -71.5539, -68.4321, -72.0154, -75.9777, and -93.7746. The docking score data suggest that curcumin was the most potential as a PLpro inhibitor, while neoandrographolide was the best as a 3CLpro inhibitor.
ALIH INFORMASI TITIK KRITIS HALAL PADA SEDIAAN KOSMETIKA HERBAL Agriana Rosmalina Hidayati; Anggit Listyacahyani Sunarwidhi; Nisa Isneni Hanifa; Neneng Rachmalia Izzatul Mukhlishah; Mahacita Andanalusia
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 6, No 4 (2022): Desember
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v6i4.11741

Abstract

ABSTRAKSaat ini produk halal telah mampu menjadi primadona yang digunakan beberapa negara untuk meningkatkan devisa, tidak terkecuali di Indonesia. Kosmetika sebagai produk dalam memelihara kecantikan semakin berkembang seiring dengan perkembangan bioteknologi. LPPOM MUI mengungkapkan ada dua titik kritis yang perlu diperhatikan dalam kehalalan produk kosmetik yaitu bahan yang digunakan dan tembus air. Kegiatan pengabdian masyarakat dalam bentuk webinar dan workshop mengenai titik kritis halal pada sediaan kosmetika herbal dilakukan untuk membantu mahasiswa memperoleh informasi dan keterampilan terkait kosmetik halal secara mendalam. Dalam kegiatan webinar, diketahui terjadi peningkatan pengetahuan antara sebelum dan setelah dilakukannya paparan materi (p-value < 0.005). Peserta dengan nilai terbaik selanjutnya mengikuti workshop pembuatan gel anti-acne dengan bahan herbal. Melalui kegiatan pengabdian ini, dapat disimpulkan     bahwa penerapan titik kritis halal pada kosmetik herbal dan formulasi kosmetik herbal halal dapat diimplementasikan untuk pengembangan produk halal di kemudian hari. Kata kunci: edukasi; titik kritis halal; kosmetika herbal; mahasiswa. ABSTRACTHalal products have become the prominance that are used in several countries to increase foreign exchange, including Indonesia. Cosmetic continues to grow along with the development of biotechnology. LPPOM MUI revealed that there are two critical points that need to be considered in the halalness of cosmetic products, such as the materials used and water permeability. Webinar and workshop on halal critical points in herbal cosmetic preparations as community service activity were conducted to help students gain in-depth information and skills related to halal cosmetics. It is known that there is an increase in knowledge between before and after the webinar activity (p-value < 0.005). Participants with the best scores then took part in a workshop on making anti-acne gel with herbal ingredients. Through this service activity, it can be concluded that the application of halal critical points in herbal cosmetics and halal herbal cosmetic formulations can be implemented for the development of halal products in the future. Keywords: education; halal critical point; herbal cosmetics; students.
Studi Etnobotani Bahan Kosmetik Asli Masyarakat Desa Tanjung Luar Kabupaten Lombok Timur, Indonesia Syavira Marwa; Raisya Hasina; Anggit L. Sunarwidhi
Jurnal Sosial dan Sains Vol. 2 No. 1 (2022): Jurnal Sosial dan Sains
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2659.106 KB) | DOI: 10.59188/jurnalsosains.v2i1.314

Abstract

Latar Belakang: Kosmetik telah menjadi kebutuhan, khususnya bagi kaum wanita. Hal ini terbukti dari pendapatan kosmetika Indonesia berjumlah Rp6,977 triliun pada tahun 2019. Kosmetik alami dapat menjadi solusi untuk mengurangi dampak buruk kosmetik sintetis. Pemanfaatan tumbuhan sebagai perawatan kecantikan di Indonesia telah dilakukan secara turun-temurun melalui tradisi lisan dan tidak terdokumentasi dengan baik, sehingga rentan terjadi kehilangan warisan leluhur. Tujuan: Penelitian ini bertujuan untuk mengetahui jenis tumbuhan yang dimanfaatkan sebagai perawatan kecantikan oleh masyarakat Desa Tanjung Luar, Indonesia. Metode: Metode yang digunakan dalam penelitian ini yaitu, metode kualitatif dan kuantitatif dengan metode sampling yaitu teknik bola salju. Pada teknik ini sampel yang diperoleh melalui proses bergulir dari satu informan penghubung ke informan kunci. Hasil: Hasil penelitian menunjukkan terdapat 71 ramuan kosmetik perawatan alami yang terdiri dari 50 spesies dari 28 famili yang tergolong dalam kategori wajah dan kulit, rambut, mata, kuku, bibir, gigi dan mulut, organ kewanitaan, pasca melahirkan dan bayi, serta penghilang bau badan. Kesimpulan: Berdasarkan hasil penelitian yang diperoleh dapat disimpulkan bahwa terdapat 71 ramuan kosmetik perawatan alami yang dimanfaatkan oleh masyarakat Desa Tanjung Luar, Indonesia yang tergolong dalam kategori wajah dan tubuh, rambut, mata, kuku, bibir, gigi dan mulut, organ kewanitaan, pasca melahirkan dan bayi, dan penghilang bau badan.
Anti-Stapylococcus Epidermidis of Methanolic Extracts from Some East Lombok Medicinal Plants Dyke Gita Wirasisya; Amni Hamid; Muhamad Haikhal; Agriana Rosmalina Hidayati; Anggit Listyacahyani Sunarwidhi; Nisa Isneni Hanifa
Jurnal Biologi Tropis Vol. 23 No. 2 (2023): April-June
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i2.4732

Abstract

Wounds are structural and functional disruptions of the skin that occur as a result of an injury. Wound healing is a complex tissue repair or remodelling process in response to the injury. The most common factor that causes wounds not properly heal is infection. An infection develops when microorganisms enter the body, multiply, and trigger an immune reaction in the body. This study aims to determine the activity of Jatropha multifida L., Stachytarpheta jamaicensis (L.) Vahl, Centella asiatica (L.) Urb., Euphorbia pulcherrima Willd. ex Klotzsch, and Angelica keiskei (miq.) Koidz has long been used to treat and manage wounds in East Lombok. The plants were dried and macerated with methanol; excessed solvent was evaporated. Disc diffusions were used to determine the antibacterial activity of the plant extracts. All extracts were tested against Staphylococcus epidermidis, a common cause of wound infection. Statistically, the activity of Jatropha multifida (5;10 mg/mL), Stachytarpheta jamaicensis (10 mg/mL), Centella asiatica (10 mg/mL), Euphorbia pulcherrima (M) (5, 10 mg/mL), and Angelica keiskei (2,5; 5; 10 mg/mL) extracts were comparable with positive control. However, Angelica keiskei has a wider inhibition zone than other extracts. This discovery could be served as a basis for using plants to aid wound healing, especially to combat the interference bacteria. However, further research is needed to discover the active phytochemicals involved in the antibacterial and wound healing process.
Co-Authors Agus Dwi Ananto Aluh Nikmatullah Amni Hamid Ari Hernawan Arinda Eka Muliani Baiq Ressa Puspita Rizma Bambang Budi Santoso Bq Tri Khairina Ilhami Dewi Suryani Dewi Suryani Dyke Gita Wirasisya Dyke Gita Wirasisya Eka Sunarwidhi Prasedya Haji Sunarpi Haji Sunarpi Harhara, Zanira Faisal Hidayati, Agriana Rosmalina Mahacita Andanalusia Muhamad Haikhal Neneng Rachmalia Izzatul Mukhlishah Ni Wayan Riyani Martyasari Nisa Isneni Hanifa Raisya Hasina Septia Budi Utami Siti Maryam Indriyati Syavira Marwa Yayuk Andayani Yogi Ambana Zanira Faisal Harhara