<![CDATA[An important goal of learning system is to deliver instruction that can produce equal or better learning outcomes. To achieve this goal, the number of research has been conducted to address the issue of what antecedent variables can affect the student learning outcomes. One of the methods which can develop student learning outcomes is case method based on flipped classroom. This research was conducted to analyze student learning outcomes using case method based on flipped classroom. This research is the quasi-experimental research with posttest only control group design. There is the control class and the experimental class in this research with a little of case method vs a lot of case method design. The participants in this study were 82 biology students using the total sampling technique. Data were analyzed using ANOVA to analyze the student learning outcome using case method based on flipped classroom. The results of study using case method based on flipped classroom has significant effect on student learning outcomes with a significance value of p < 0.05 with F (6.59) = 3.97, p=.012. Thus, it can be concluded that the case method which is combine with flipped classroom gives the positive impact on student learning outcomes]]>
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