cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Dr. Ir. Dyah Rini Indriyanti
Contact Email
biosaintifika@mail.unnes.ac.id
Phone
-
Journal Mail Official
biosaintifika@mail.unnes.ac.id
Editorial Address
-
Location
Kota semarang,
Jawa tengah
INDONESIA
Biosaintifika: Journal of Biology & Biology Education
Published by Universitas Negeri Semarang
ISSN : 2085191X     EISSN : 23387610     DOI : -
Core Subject : Agriculture,
Agriculture, Biological Sciences & Forestry
Biosaintifika Journal of Biology & Biology Education, an electronic international journal, provides a forum for publishing the original research articles, review articles from contributors, and the novel technology news related to biological research and biological education.
Arjuna Subject : -
Articles 16 Documents
 1   2 
Search results for , issue "Vol 13, No 3 (2021): December 2021" : 16 Documents clear
Utilization of Quercetin Flavonoid Compounds in Red Onion (Allium cepa L.) as Inhibitor of Spike Sars-CoV-2 Protein against ACE2 Receptors Syifa Zahara Kultsum Azmi; Sunarno Sunarno; Sinta Aulia Rahmah; Melisa Andriani; Azlya Reza Lailul Farobi; Luke Nur Ahlina
Biosaintifika: Journal of Biology & Biology Education Vol 13, No 3 (2021): December 2021
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v13i3.32027

Abstract

The world is facing the challenge of the COVID-19 disease, which is now stated as a pandemic. Inside the host cell, spike envelope protein (spike) of SARS-CoV-2 interact with the Angiotensin-converting Enzyme 2 (ACE2) receptor. It can be inhibited by bioactive compounds such as flavonoids which have anti-viral and broad pharmacological effect. This study aimed to determine the spike protein inhibitory activity by quercetin against the ACE2 receptor using the molecular docking method. This study focused on the inhibitory of the penetration activity of s proteins in ACE2 by utilizing natural material compounds that have the potential to be used as anti-SARS-CoV-2 drug development agents. The flavonoid compound quercetin was extracted by the maceration method. The quantitative analysis was carried out using a UV-Vis spectrophotometer to prove the presence of quercetin content. Molecular docking simulations were carried out to look for the binding affinity between the spike protein and quercetin. Docking was carried out using the Autodock, PyRx, and visualization using Discovery Studio. Indicators that prove that quercetin forms binding affinity and protein complexes with spikes are the Vina Score and RMSD. It is also supported by ADME analysis and conformity to Lipinski's rules of five. That matter becomes a success indicator of the spike activity inhibition by quercetin, which makes it possible to be used as an anti-SARS-CoV-2 drug development agent. The novelty from this study is molecular docking method that used to show that quercetin in red onion had inhibitory activity on the penetration process of protein spike in SARS-CoV-2. Results obtained from this study can be used as a recommendation for advanced research in invitro and invivo studies as a drug which has potential to inhibit protein spike of SARS-CoV-2.
Production Improvement of M1 Generation Garut (Maranta arundinacea) Rhizomes through Gamma Radiation Mutation Puspita Deswina; Dody Priadi; Yashanti Berlinda Paradisa; Yuliana Galih Dyan Anggraheni; Enung Sri Mulyaningsih; Ambar Yuswi Perdani; Sri Indrayani
Biosaintifika: Journal of Biology & Biology Education Vol 13, No 3 (2021): December 2021
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v13i3.31383

Abstract

Garut (Maranta arundinacea L.) is a tuber containing flour with a low Glycemic Index (IG) suitable for diabetics and other degenerative diseases. It needs to be developed to reduce the dependence on imports or to substitute wheat flour. The objective of the study was to obtain superior arrowroot seedlings and observe the effect of gamma-ray irradiation on the density and position of stomata on arrowroot leaves. In this research, the irradiation of five arrowroot accessions of second-generation (MV1) with gamma rays (0, 10, 20, 30, 40, and 50 Gray) was carried out to obtain mutants with superior character so that they could be used as parent plants for arrowroot flour production. The treatments administered were arrowroot accessions (V), gamma-ray radiation dose (R), and their interaction. The qualitative and quantitative characters on plant characteristics, tuber production, and arrowroot leaves' stomata were observed. The research results showed that increased production is primarily for 25-Pandeglang accession (808.33 grams) and 10 Gray (800.00 grams) of gamma ray radiation treatment. It is expected that this accession can be released as a new variety candidate after subsequent selection and evaluation in a further generation. Moreover, the dose of gamma-ray radiation is inversely proportional to the number of stomata, which will increase the photosynthesis, thus increasing the number of tubers produced.
Trichoderma hamatum derived from coffee plant ( Coffea canephora ) rhizosphere inhibit Candida albicans Growth Yuyun Nisaul Khairillah; Nampiah Sukarno; Irmanida Batubara
Biosaintifika: Journal of Biology & Biology Education Vol 13, No 3 (2021): December 2021
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v13i3.31132

Abstract

The Trichoderma hamatum produces various secondary metabolites that can be used as Candida albicans.  This research aimed to isolate T. hamatum from the coffee (Coffea canephora) rhizosphere and analyze the fungal compounds to control the pathogenic fungus C. albicans. T. hamatum was isolated using the dilution method, and the fungal identification was used, combining morphological and molecular characteristics of ITS rDNA. The potency of T. hamatum as C. albicans was determined by antagonist test using the double-layer method, while for culture filtrate, ethyl acetate and n-hexane filtrate extracts were carried out by the agar diffusion method. The compounds in the most active extract were analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). T. hamatum inhibits C. albicans growth in antagonistic and filtrate with 15.53 mm and 14.40 mm of inhibition zone. It indicated that both culture and fungal filtrate had similar activities on C. albicans. The ethyl acetate extract (minimum inhibitory concentration, MIC of 0.50%) showed more potent against C. abicans than n-hexane extract (MIC of 15.00%). The potential active compound in the ethyl acetate extract would be 9-Octadecenoic acid (Z) methyl ester. The 9-Octadecenoic acid (Z) methyl ester could be used as an alternative candidate to control Candida.
Determination of Proximate Composition of Local Corn Cultivar from Kisar Island, Southwest Maluku Regency Hermalina Sinay; Nunung Harijati
Biosaintifika: Journal of Biology & Biology Education Vol 13, No 3 (2021): December 2021
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v13i3.30527

Abstract

As a staple food, which consumed by many peoples in almost all places world wide, corn (Zea mays L.) has become very important. As well as in Indonesia, especially in Kisar Island, Southwest Maluku regency, corn already be the one of the most important food crops. The purpose of this study was to determine proximate content of local corn kernels from Kisar Island Maluku. Proximate analysis included content of water, fat, protein, ash, crude fiber, total carbohydrate and total sugar. Data collected are presented in form of table and analyzed descriptively. The data obtained were compared to the Indonesian national standard (SNI) of proximate content for corn kernels as well as to other results that have been reported by several researchers. The results of seven local corn cultivars from Kisar Island were in accordance with SNI standards about content of ash (1.13-2.04%), protein (9.14-13.02%), crude fiber (2.17 - 2.72%), fat (3.47-5.10% ), total carbohydrate (69.7 % -75.74%), and total sugar (58.66% -68.7%). The novelty of this research is to reveal the proximate content of local corn kernels from Kisar Island. This research is expected to be useful as a source of information about the proximate content of local corn seeds, and for instance it can be considered in the utilization and development of local corn in Kisar Island.
Types of Rats and Their Parasites That Potential to Transmit Disease in Tugu District, Semarang City Ning Setiati; Rusyda Auliya; Partaya Partaya; F. Putut Martin Herry Bodijantoro; Dyah Rini Indriyanti; Priyantini Widiyaningrum
Biosaintifika: Journal of Biology & Biology Education Vol 13, No 3 (2021): December 2021
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v13i3.33460

Abstract

Rats are known as vectors and reservoirs for various types of ecto and endoparasites. The existence of rats as cosmopolitan animals allows for complex parasitic transmission due to the relationship between humans, animals, and the environment. This study aimed to provide informative data on the types of rat along with their ecto- and endoparasites. This research is a qualitative descriptive study. Data collection was carried out by random sampling survey with a point time approach. Data collection was carried out in 4 villages, namely Tugurejo, Mangkang Wetan, Mangunharjo, and Mangkang Kulon Villages, Tugu District, Semarang City. A total of 89 rats were obtained, the species obtained were R. norvegicus, R. argentiventer, R. exulans, R. tiomanicus, R. surifer, R. tanezumi, B indica, and S. murinus. Ectoparasite infestation was found in all types of rats except S. murinus. The ectoparasites found were Xenopsylla cheopis and Laelaps echidninus which were reported as the main vectors of murine typhus, epidemic typhus, bartonellosis as well as scrub typhus and Q-fever disease. Endoparasite infestation was found in the intestinal organs, namely Diphyllobothrium sp. and two species of worm eggs Hymnoepis sp. and Trichuris trichiura which were reported as the cause of Diphyllobothriasis as well as digestion, absorption, which can result in the loss of protein, carbohydrates, fats, and blood in large quantities. Diphyllobothriasis is not transmitted from person to person, more than one family member can be infected by sharing common meals and having similar eating habits. This study can be used as an early warning for community against the potential of infectious diseases from rats as vectors in Tugu District, Semarang related to rats density, endoparasites and their ectoparasites.
Morphological Differences between Chaetodon auriga and Chaetodon vagabundus based on Truss Morphometric Characters Rosewitha Anggraeni Privieshanti Hadi; Elly Tuti Winarni; Dian Bhagawati; Agus Nuryanto
Biosaintifika: Journal of Biology & Biology Education Vol 13, No 3 (2021): December 2021
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v13i3.31466

Abstract

Chaetodon auriga and Chaetodon vagabundus are popular marine aquaria fish from Cahetodontidae family. Both species show subtle morphological variations, especially in juvenile stages, which might lead to misidentification. Additional morphological characteristics, such as truss morphometric, are valuable characters for species identification in Chaetodontidae. This study aimed to evaluate morphological differences between Chaetodon auriga and C. vagabundus based on truss morphometric characters. The study is expected to provide new morphometric characters for Chaetodon auriga and C. vagabundus differentiation on the southern coast of West Java, Indonesia. Fish samples were collected from Ujunggenteng and Taman Manalusu Beach. The specimens were identified based on morphological characteristics and referred to the characters available in the literature. Truss morphometric characters were measured using callipers with an accuracy of 0.01mm and convert to ratio values to obtain constant value. The data were analyzed statistically using the Mann-Whitney test in SPSS software packages. The result showed that five truss morphometric characters were significantly different between C. auriga and C.vagabundus.  This study concluded that C. auriga and C. vagabundus could be differentiated using truss morphometric character. This study provides five new morphometric characters for species differentiation in fish species, especially between C. auriga and C. vagabundus.
Removal of Textile Dye, RBBR, via Decolorization by Trametes hirsuta AA-017 Fina Amreta Laksmi; Eva Agustriana; Isa Nuryana; Rike Rachmayati; Urip Perwitasari; Rumaisha Rumaisha; Ade Andriani
Biosaintifika: Journal of Biology & Biology Education Vol 13, No 3 (2021): December 2021
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v13i3.31632

Abstract

The use of synthetic dyes has an impact on the possibility of disposing such dyes into the environment. Fungal decolorization is one promising approach due to its capability to degrade dyes, thus, exploring fungi that can be applied in dye decolorization is essential. We investigated our potential strain of Trametes hirsuta to decolorize Remazol brilliant blue R (RBBR). The enzyme activity of laccase in various conditions was observed using Syringaldazine as a substrate, while fungal immobilization was conducted using calcium alginate as a solid support. The results indicated that CuSO4 was the best inducer for the decolorization process. The fungus was able to perform 79.5% of RBBR decolorization for 48 hours in the presence of CuSO4. Laccase was the prominent detected ligninolytic enzyme when decolorization was performed. The immobilized cells were able to decolorize 85% RBBR under 0.8 mM CuSO4 andused for 3 cycles of decolorization. This study reveals the potential of fungal usage in the form of the immobilized and free cell to overcome the persistence of dye pollutants problem, as it is considered an effective, economic and eco-friendly approach for RBBR dye decolorization. These strategies can be suggested to encourage ecologically sustainable development for bioremediation.
Histomorphometry of the Duodenum of Ducks (Anas platyrhyncos) after Administration of Nanochitosan in Feed Sunarno Sunarno; Solikhin Solikhin; Kustopo Budiraharjo
Biosaintifika: Journal of Biology & Biology Education Vol 13, No 3 (2021): December 2021
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v13i3.32120

Abstract

Poultry farming business has several problems such as lack of availability on raw materials, expensive feed prices, and egg production that is not optimal. To overcome the problem of high feed prices and duck productivity, we need to add feed additives such as nanochitosan. Poultry farming business has several problems such as lack of availability on raw materials, expensive feed prices, and egg production that is not optimal. To overcome the problem of high feed prices and duck productivity, we need to add feed additives such as nanochitosan. This study aimed to analyze the effect of nanochithosan feed on the digestive function of the intestine tenue (duodenum) as indicated by histomorphometric changes in the duodenum of Tegal ducks (Anas platyrhyncos). Duodenal histomorphometry related to digestive function was measured, including changes in lumen diameter, villi height, epithelial cell thickness, and muscular layer thickness. This study used a completely randomized design consisting 5 treatments with 5 replications. The research treatments included P0 as control (basic feed without nanochitosan particle additives) and P1, P2, P3, and P4 (basic feed with the addition of nanochitosanwith the doses of 2.5; 5; 7.5; and 10 grams/kg feed respectively). The variables observed were lumen diameter, villi height, epithelial layer thickness, and duodenal muscle layer thickness. The research data were analyzed using the analysis of variance (ANOVA) with a 95% confidence level. The results showed that the addition of nanochitosan particles in the feed had a significant effect on the lumen diameter and thickness of the duodenal muscular layer (P0.05). Tegal ducks. The conclusion of this study is that nanochitosan feed additives with a concentration of 2.5-10% can improve digestive function and improve duodenal histomorphometry in the intestine tenue of Tegal ducks as indicated by an increase in lumen diameter, villi height, and the thickness of epithelial cell thickening, and muscular layer. The novelty from this study is the production and the used of nanochitosan as feed additive to repair histomorphometry of duodenum in intestine tenue of Tegal ducks. From this research, people gets benefit by knowing the use nanochitosan as feed additive to improve digestion performance and productivity of Tegal ducks.
Species Diversity of Epiphyte Fern Plants in Curug Lawe Waterfall Region, Semarang District Rizky Wahyu Saputro; Sri Utami; Lilih Khotimperwati
Biosaintifika: Journal of Biology & Biology Education Vol 13, No 3 (2021): December 2021
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v13i3.31422

Abstract

Epiphyte fern plants are fern plants that grow attached to the phorophyte tree. Existence of fern plants are effected by tree bark and environmental condition in which they grow. This research aimed to study the species composition, important value index, diversity index, evenness index, and similarity index of epiphyte fern plants in the Curug Lawe Waterfall Region Semarang District. This research was conducted on 5 research stations i.e. clove plantations area (CPA), irrigation canal (IC), mixed forest (MF), river flow (RF), and waterfall area (WA). The research used plot technique with plot size 10 m x 10 m. The results showed 11 species of epiphyte fern from 8 families were found. The highest important value index is obtained by Goniophlebium serratifolium. The diversity index of epiphyte fern plants are categorized as low and moderate. The evenness index of epiphyte fern plants are categorized as not evenly distributed, quite evenly distributed, and almost evenly distributed. The highest similarity index is in irrigation canal (IC) and river flow (RF). Environmental conditions in Curug Lawe Waterfall Region are suitable for epiphyte fern plants habitat. This research is novel as it provides some information about the community structure of epiphyte ferns in Curug Lawe Waterfall Region and to engage all peoples to maintain our biodiversity keep sustainable.
Educational Values of Roadside Trees in Carcar City, Cebu, Philippines: Implications to Environmental Education Joje Mar Perino Sanchez; Aila Louella Marie I. Teologo; Rhona R. Villamejor; Grazen Brithzel T. Rieta; Jeanne S. Oberes; Jessa O. Romeo; Zandher Austin D. Pahamotang; Shervi A. Gempisao; Lenylyn E. Villarojo
Biosaintifika: Journal of Biology & Biology Education Vol 13, No 3 (2021): December 2021
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v13i3.31283

Abstract

Roadside trees along the national highway in Barangay Perrelos in Carcar City are trees that considered a heritage, and yet are affected by urban developments in the province. The study determined the profile of the roadside trees as well as the knowledge, attitudes, and conservation efforts of the locals in the area. Questionnaires and interviews were given to 50 respondents, and data gathered were analyzed using ANOVA, Pearson r and thematic analysis. Ecological indices such as abundance percentage and species richness were also used by the study. Results revealed that there are 108 identified roadside trees, where the species richness is 0.962 and acacia trees are the most abundant (46.30%). Knowledge and attitudes of the respondents were high and low-to-moderate, respectively. Conservation practices towards the roadside trees included pruning, no burning near the trees and making of diversion roads, all adhering with existing environmental laws of the country. Tree abundance and richness, knowledge acquisition, attitude inculcation, and conservation efforts are manifestations of the educational values of roadside trees to the people. Research on these educational values of trees is novel as it provides importance on cultural heritage, environmental protection, and sustainable planning in the area. Implications to environmental education are formulated for the Philippine elementary and secondary education Science teaching.  

Page 1 of 2 | Total Record : 16

 1   2 

Filter by Year

2021 2021


Reset
Filter By Issues
All Issue Vol 15, No 3 (2023): Inpress December 2023 Vol 15, No 2 (2023): August 2023 Vol 15, No 1 (2023): April 2023 Vol 14, No 3 (2022): Desember 2022 Vol 14, No 2 (2022): August 2022 Vol 14, No 1 (2022): April 2022 Vol 13, No 3 (2021): December 2021 Vol 13, No 2 (2021): August 2021 Vol 13, No 1 (2021): April 2021 Vol 12, No 3 (2020): December 2020 Vol 12, No 2 (2020): August 2020 Vol 12, No 1 (2020): April 2020 Article-in-Press Vol 12, No 1 (2020): April 2020 Vol 11, No 3 (2019): December 2019 Vol 11, No 2 (2019): August 2019 Vol 11, No 1 (2019): April 2019 Vol 11, No 1 (2019): April 2019 Vol 11, No 3 (2019): Article-in-Press Vol 10, No 3 (2018): December 2018 Vol 10, No 3 (2018): December 2018 Vol 10, No 2 (2018): August 2018 Vol 10, No 2 (2018): August 2018 Vol 10, No 1 (2018): April 2018 Vol 10, No 1 (2018): April 2018 Vol 9, No 3 (2017): December 2017 Vol 9, No 3 (2017): December 2017 Vol 9, No 2 (2017): August 2017 Vol 9, No 2 (2017): August 2017 Vol 9, No 1 (2017): April 2017 Vol 9, No 1 (2017): April 2017 Vol 8, No 3 (2016): December 2016 Vol 8, No 3 (2016): December 2016 Vol 8, No 2 (2016): September 2016 Vol 8, No 2 (2016): September 2016 Vol 8, No 1 (2016): March 2016 Vol 8, No 1 (2016): March 2016 Vol 7, No 2 (2015): September 2015 Vol 7, No 2 (2015): September 2015 Vol 7, No 1 (2015): March 2015 Vol 7, No 1 (2015): March 2015 Vol 6, No 2 (2014): September 2014 Vol 6, No 2 (2014): September 2014 Vol 6, No 1 (2014): March 2014 Vol 6, No 1 (2014): March 2014 Vol 5, No 2 (2013): September 2013 Vol 5, No 2 (2013): September 2013 Vol 5, No 1 (2013): March 2013 Vol 5, No 1 (2013): March 2013 Vol 4, No 2 (2012): September 2012 Vol 4, No 2 (2012): September 2012 Vol 4, No 1 (2012): March 2012 Vol 4, No 1 (2012): March 2012 Vol 2, No 2 (2010): September 2010 Vol 2, No 2 (2010): September 2010 Vol 2, No 1 (2010): March 2010 Vol 2, No 1 (2010): March 2010 Vol 1, No 1 (2009): March 2009 Vol 1, No 1 (2009): March 2009 More Issue