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Laila Susanti
Contact Email
laila.susanti@utb.ac.id
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laila.susanti@utb.ac.id
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Kota bandar lampung,
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INDONESIA
JFL : Jurnal Farmasi Lampung
ISSN : 23552506     EISSN : 25984896     DOI : -
Core Subject : Health, Science,
The focus of JFL is to become a media for the publication of articles on Pharmaceutical and related practice-oriented subjects in the pharmaceutical sciences, natural medicine and clinic community. The scope of the journal is Pharmaceutical sciences, its research and its application.
Arjuna Subject : -
Articles 8 Documents
Search results for , issue "Vol. 9 No. 1 (2020): JFL: Jurnal Farmasi Lampung" : 8 Documents clear
FRAKSI AIR EKSTRAK DAUN WUNGU (Graptopphyllumpictum L.) SEBAGAI ANTIINFLAMASI TERHADAP TIKUS PUTIH JANTAN Ramadhan Triyandi; Akhmad Rokiban; Catur Setia Pratiwi MS
JFL : Jurnal Farmasi Lampung Vol. 9 No. 1 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i1.325

Abstract

Abstract This study aims to determine the anti-inflammatory effect of the water extract of Daun wungu (Graptophyllum pictum L.) extract which was observed from the decrease in the volume of edema of rat’s feet which was induced by 1 % carrageenan as much as 0,1 ml, was carried out in 25 male white rats divided into 5 groups. Negative controlwas given distilled water given 5 % Na CMC, diclofenac sodium as a positive control with a dose of 0,9 mg/200 g BB and water fraction of wungu leaf extract with a dose 1 (1,125 mg/kg bb), dose 2 (2,25 mg/kg bb) dan dose 3 (4,5 mg/kg bb). The measurement of edema volume is carried out every hour for six hours after induced carrageenan. From the results of testing the water fraction of wungu leaf extract, % inhibition showed that the dose group 3 (4,5 mg/kg bb) had anti-inflammatory activity that was comparable to the positive control group. Of all dosage variatons in this study the effective dose which has the highest percentage of edema is the dose 3 (4,5 mg/kg bb). Based on the results of statistical analysis, the percentage of edema inhibition data on the water fraction of wungu lear extract from all dose variations showed significant differences with negative controls. Keyword : Graptophyllum pictum L Anti-Inflamasi
UJI TOKSISITAS EKSTRAK ETANOL DAUN JAMBU BIJI AUSTRALIA (Psidium guajava L) DENGAN METODE BSLT (Brine Shrimp Lethality Test) Nofita Nofita; Ade Maria Ulfa; Miera Delima
JFL : Jurnal Farmasi Lampung Vol. 9 No. 1 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i1.326

Abstract

ABSTRACTGuava is one of the plants that can traditionally be used for the treatment of diseases. Many kinds of guava, one of which is the Australian guava has the characteristics of roots, stems, leaves, dark red fruit. This study aims to determine the toxicity of the ethanol extract of Australian guava leaves (Psidium guajava L) using the BSLT (Brine Shrimp Lethality Test) method and determine the chemical content of Australian guava leaves (Psidium guajava L). The extract was made by the ultrasonic method using 96% ethanol solvent. Toxicity tests were carried out using 48-hour-old Artemia salina Leach shrimp larvae. The toxic effect of the extract was identified by the percentage of shrimp larvae mortality using probit analysis (LC50). From the research results, phytochemical content includes tannins, flavonoids, alkaloids, terpenoids and saponins, and flavonoid compounds have the highest content compared to the others. Research shows that the ethanol extract of Australian guava leaves is of a moderate category (LC50 441,977 ppm).Keywords :Australia guava leaves, BSLT, Artemia salina L, Ultrasonic
UJI AKTIVITAS ANTIBAKTERI SPRAY BAU KAKI EKSTRAK KULIT JERUK NIPIS (Citrus aurantifolia) DENGAN VARIASI Gelling agent TERHADAP BAKTERI Bacillus subtilis Ade Maria Ulfa; Nofita Nofita; Bangun Saras Sandi
JFL : Jurnal Farmasi Lampung Vol. 9 No. 1 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i1.327

Abstract

ABSTRACT Sweat is produced by the apocrine glands, if infected by bacteria that play a role in the decay process will certainly produce foot odor. Some of the bacteria that cause, including Staphylococcus epidermis, Corynebacterium acne and there is one bacterium that causes pungent foot odor that is Bacillus subtilis. Bacillus subtilis enzyme leucine dehydrogenase produced the highest, resulting in isovaleric acid foot odor. Lime peel (Citrus aurantifolia) has the potential to be developed for the antibacterial active ingredient of foot odor contained in tannins, alkaloids and flavonoids. Spray can be effective for inhibition of feet due to water fleas or bacterial infections. The purpose of this research is to test the inhibitory zone of the preparation of foot odor spray ethanol extract of lime peel (Citrus aurantifolia) with variations of gelling agent. Bacterial inhibition zone testing on extracts of lime peel spray preparations using the disc method. This test was carried out on spray with extract concentration of 0% extract base carbopol, 0% extract base HPMC, 0.2% extract base carbopol, 0.2% extract base HPMC, 0.4% extract base carbopol, 0.4% extract base HPMC and positive control with an average inhibition zone of 9,13 mm, 9,12 mm, 11,86 mm, 11,29 mm, 13,17 mm, 12,30 mm, 8,13 mm against the bacterium Bacillus subtilis. Antibacterial test results were analyzed using ONE WAY ANOVA, the results of statistical analysis on the preparation of lime peel extract showed a significant inhibition zone difference of 0.000 (P = <0.05) between all concentrations. Lime peel extract spray is effective in inhibiting the bacterium Bacillus subtilis. Key words: Sweat of foot odor, Lime skin (Citrus aurantifolia), Spray, bacteri Bacillus subtilis
RASIONALITAS PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN HIPERTENSI RAWAT INAP DI RS DAERAH Dr. A. DADI TJOKRODIPO BANDAR LAMPUNG Mashuri Yusuf; Subur Widodo; Diah Pitaloka
JFL : Jurnal Farmasi Lampung Vol. 9 No. 1 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i1.329

Abstract

Abstract Hypertension is one of non contagious diseases marked by the increase of systolic blood pressure > 140 mmHg and diastolic blood pressure > 90 mmHg. Hypertension becomes the main risk factor of other cardiovascular diseases. The number of hypertension occurance with or without companion increases every year. The purpose of this research is to know the rationality of anti - hypertension medicine usage on hypertension inpatients at RSUD of Dr. A. Dadi Tjokrodipo Bandar Lampung year of 2019 based on precise patient, precise indication, precise medicine, and precise dosage using reference standard of Guidelines JNCVIII. This research was a descriptive research with data collection of medical record retrospectively. The technique of sample selection used purposive sampling technique. The research results obtained from 82 samples based on the patients’ characteristics of genders such as 50 female patients (60,98%) and 42 male patients (39,02%). The patients’ characteristics based on age obtain mostly the patients are at age of 46-55 years old in the amount of 39 patients (47,6%). The patients’ characteristics based on the pattern of medicine usage obtain the most anti-hypertension used is amlodipin CCB class in the amount of 54 patients (45%). Rationality evaluation of anti-hypertension medicine usage obtains precise patient in the amount of 81 patients (99,8%), precise indication in the amount of 82 patients (100%), precise medicine in the amount of 61 patients (74,4%), and precise dosage in the amount of 82 patients (100%). The conclusion of this research is the usage of hypertension on the hypertension inpatients at Public Hospital of Dr. A. Dadi Tjokrodipo Bandar Lampung is already rational. Keywords: Anti-hypertension, Hypertension, Rationality of Medicine Usage
EVALUATION OF THE USE OF ANTIMALARIA MEDICINES IN HANURA HEALTH CENTRE PESAWARAN DISTRICT PERIOD JANUARY-DECEMBER IN 2018 Akhmad Rokiban; Ramadhan Triyandi; Karnila Sari
JFL : Jurnal Farmasi Lampung Vol. 9 No. 1 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i1.330

Abstract

Abstract Malaria is a public health problem in Indonesia, especially those living in isolated areas. This is published in Presidential Regulation No. 5/2010 concerning the National Medium Term Development Plan for malaria endemic areas, which are divided into high, medium and low endemic areas. High endemic if the API is greater than 50 out of 1,000 population in the provinces of Maluku, Papua, North Sumatra and East Nusa Tenggara. Moderate endemic if the API is 1 to less than 50 dari 1,000 population in the provinces of Aceh, Bangka Belitung, Jambi and West Nusa Tenggara. Low endemic if the API is 0-1 per 1,000 population in Kalimantan, Sulawesi, and parts of Java. This study aims to determine the evaluation of the use of antimalarial drugs with the characteristics of age, sex, and type of malaria plasmodium at the Hanura Public Health Centre based on the criteria of the right indication, the right drug, the right dose, the right interval of drug administration (4T). This research is a descriptive research with purposive sampling method. Collection of prescription data and medical records in January-December 2018. The results showed that in cases of Malaria based on age, the most common cases occurred in the age range of 56-65 years, amounting to 99.6%, based on sex experienced in men by 77.41%, based on body weight the most occurred at 41-59 kg at 45.16%, based on the type of plasmodium experienced plasmodium vivax mostly at 84.95%. Based on these data, it was concluded that the evaluation of the use of antimalarial drugs based on 4T criteria was 100% accurate indication, 100% correct drug, 72.04% correct dose, 98.92% correct interval of drug administration. Keywords: Malaria vivax, treatment, Puskesmas, 4T
ANALISIS KADAR NITRIT PADA SOSIS SAPI KEMASAN YANG BEREDAR DI PASAR TRADISIONAL KOTA BANDAR LAMPUNG SECARA SPEKTROFOTOMETRI UV-VIS Samsuar Samsuar; Akhmad Rokiban; Dodo Hardoyo
JFL : Jurnal Farmasi Lampung Vol. 9 No. 1 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i1.331

Abstract

Abstract The use of nitrite as a preservative and provider of the stable red color, aroma as well as taste for the meat is allowed within processed meat products, such as beef sausage. However, it should be noted that its use does not exceed the maximum permitted limit so as not to negatively impact human health. Excess nitrite in the human body can cause acute poisoning, namely methemoglobinemia and chronic poisoning as a result of the formation of carcinogenic nitrosamine derivatives. This research aims to determine whether the levels of nitrite contained in the packaged beef sausage distributed in the traditional market of Bandar Lampung is in accordance with the regulations of The Indonesia Food and Drug Authority or Indonesia FDA No. 36 of 2013 which is not more than 30 mg/kg. The analysis of nitrite levels in the sample was carried out using with UV-Vis Spectrophotometry method based on diazotation reaction between nitric acid and sulfanilamide forming diazonium salts. The products were then reacted again with naphthyl ethylenediamine to form a purplish red compound whose absorbance was measured at a wavelength 0f 543,8 nm. From the results of the analytical methods validation, it was obtained that the value of the correlation coefficient was 0,9997, the coefficient of determination 0,9994, the coefficient of variation 1,2121%, the range of percent recovery between 98,630-101,240%, and the detection and the quantitation limit respectively at 0,0187 ppm and 0,0623 ppm. This indicates that all test parameters meet the requirements for their use. The result of determining the average levels of nitrite in the samples show that there were two samples that had levels exceeding the maximum allowed limit, i.e sampel C=40,407 mg/kg and sample D=33,181mg/kg while sample A=18,963 mg/kg, sample B=9,427 mg/kg, sample E=9,423 mg/kg and sample F=8,689 mg/kg did not exceed the maximum allowed limit. Keywords: Beef Sausage, Nitrite, UV-Vis Spectrophotometry, Method AnalysisValidation
EVALUASI PENGGUNAAN OBAT PADA PENDERITA DIARE AKUT PASIEN PEDIATRI DI INSTALASI RAWAT INAP RUMAH SAKIT ADVENT BANDAR LAMPUNG PERIODE JULI – DESEMBER 2019 Subur Widodo; Novita Tri Wahyuni; Lea Yekti Utami
JFL : Jurnal Farmasi Lampung Vol. 9 No. 1 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i1.333

Abstract

Abstract Acute diarrhea is diarrhea that lasts less than 14 days. Regarding its severity, acute diarrhea is classified as mild, moderate or severe. Mild when signs of dehydration are not observed, moderate when there are mild or moderate signs of dehydration and rehydration can be done orally and severely when it results in more intense dehydration with or without electrolyte disturbances, and requires intravenous therapy. Diarrhea disease in the Inpatient Installation Bandar Lampung Adventist Hospital is the 10 biggest diseases and has never been evaluated on the use of drugs in pediatric patients. This study aims to evaluate the use of drugs in patients with acute diarrhea inpatients installation at the Bandar Lampung Adventist Hospital calculated from July to December 2019 data. This research is a descriptive study with retrospective data collection. The data collection process begins by tracing medical records of acute diarrhea patients. The population of acute diarrhea cases was 152 patients and then the number of samples obtained was then selected according to the inclusion criteria as a sample of 60 patients. From the research results it is known that the use of drugs in patients with acute diarrhea in pediatric patients includes antibiotics, electrolyte solutions, analgesic/antipyretics, antidiarrheals and other drugs (antihistamines, supplements and probiotics). The validation of drug use on the right indicators, the right patient and the right dose has reached 100%, the right indicator is 37% and the drug is 63% incorrect, this is due to the use of antibiotics without laboratory results that show acute diarrhea due to infection. Keywords: acute diarrhea, evaluation of drug use, pediatric
EVALUASI RASIONALITAS PENGGUNAAN OBAT DIABETES MELITUS TIPE II PADA PASIEN RAWAT JALAN DI PUSKESMAS PASIR SAKTI TAHUN 2019 Dwi Aulia Ramdini; Lilik Koernia Wahidah; Dwi Atika
JFL : Jurnal Farmasi Lampung Vol. 9 No. 1 (2020): JFL: Jurnal Farmasi Lampung
Publisher : Fakultas MIPA Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v9i1.334

Abstract

Abstract Diabetes mellitus is a metabolic disease characterized by hyperglycemia, due to abnormal insulin secretion, insulin action or both. Hyperglycemia is a condition in which blood glucose levels increase or exceed normal limits. This study aims to evaluate the treatment of type II diabetes mellitus in outpatients in Puskesmas Pasir Sakti. This research is a nonexperimental research with a descriptive design taken retrospectively. The sample in this study were all outpatients with a diagnosis of type II diabetes mellitus at Puskesmas Pasir Sakti 2019. The sampling technique used was Total sampling. The sample of this study is the medical record data of patients with type II diabetes mellitus in 2019 adjusted for inclusion criteria. Characteristics based on gender of patients with type II diabetes melitus there are 23 male patients that is 29% and 57 female patients that is 71 %. Characteristics based on the age of most patients in the Elderly (46-65 years) as many as 65 patients (81%). cases of type II diabetes mellitus patients without complications were 39 patients (49%) cases of type II diabetes mellitus patients with complications of 41 patients (51%). The results of the rationality of antidiabetic use in outpatients at the Puskesmas Pasir Sakti in 2019 According to PERKENI 2015 obtained the use of drugs based on the exact parameters indicated as much as 97.5%, the right drugs as much as 98.75%, the right dosage as much as 100%, the right way of administration as much as 100%, the exact time interval of 100%, and medication adherence of 100%. Treatment of type II diabetes melitus who received rational therapy was 96,25% while irational therapy is 3,75%. Keywords: Diabetes Mellitus, Evaluation, Medicine, Rationality.

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