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Medica Hospitalia

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Published by RSUP Dr. Kariadi Semarang

ISSN : 23014369 EISSN : 26857898 DOI : https://doi.org/10.36408/mhjcm

Core Subject : Health,

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Medica Hospitalia: Journal of Clinical Medicine adalah jurnal ilmiah yang diterbitkan RSUP Dr. Kariadi dan menerima artikel ilmiah dalam bahasa Indonesia dan bahasa Inggris yang diharapkan dapat menjadi media untuk menyampaikan temuan dan inovasi ilmiah dibidang kedokteran atau kesehatan kepada para praktisi dan akedemisi di bidang kesehatan dan kedokteran.

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Search results for , issue "Vol. 7 No. 2 (2020): Med Hosp" : 21 Documents clear

Pengaruh Pemberian Aromaterapi Lemon terhadap Skor Kecemasan Mahasiswi Fakultas Kedokteran Universitas Diponegoro Alifiati Fitrikasari; Nur Isnaeni Fajriyanti; Natalia Dewi Wardani; Innawati Jusup
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Background: Based by Riskesdas in 2013, 6% of Indonesia’s population the age of 15 years old and more had emotional disorders which shown by symptoms of anxiety and depression. In university students, the study found that 25% of them had light anxiety, 60% had moderate anxiety, and 15% had severe anxiety. The mean of medical student who had anxiety symptoms around the world are 12-69%. Relaxation therapy able to decrease anxiety level, which by giving aromatherapy, it able to stimulates the brain to relax. Lemon is one of the aromatherapies that found effectively able to decrease anxiety symptoms by its refreshingly sharp smell and lifting the mood, which strengthening its user’s psyche. To measure the anxiety score, the author used the Zung Self-rating Anxiety Scale (ZSAS). The objective of this study aimed to investigate the effect of inhaling lemon aromatherapy on anxiety in female students of Medical Faculty of Diponegoro University Methods: This study used experimental pre and post-test without control design. Zung Self-rating Anxiety Scale was used to investigate the anxiety level of the samples. 32 persons volunteered as participants by 1 of them dropped out. The group inhaled lemon aromatherapy for 2 weeks. At the end of week 2, the participants’ anxiety was measured, and the results were statistically analysed. Saphiro-Wilk Test was used as the normality test while the results of the measured anxiety were tested by Wilcoxon Test. Results: There was a significant decreased anxiety score of the participants after inhaling lemon aromatherapy for two weeks. Based by pre and post-test result, the mean of anxiety score decreased from 37.32 to 31.84 (p=0.000). Conclusions: Lemon aromatherapy essential oil is able to significantly decrease the anxiety score of female students of Faculty of Medicine Diponegoro University. Keywords: Lemon aromatherapy, anxiety, medical student

Perbandingan Terapi Antibiotik Ceftriakson Rute Intervena Bolus dan Intravena Drip terhadap Penurunan Kadar Procalcitonin dan Asam Laktat Pasien Sepsis Jainuri Erik Pratama; Heri Sutanto
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar belakang: Ceftriaxone merupakan antibiotika golongan bakterisida dan termasuk dalam golongan antibiotic time dependent. Efek bakterisidal yang optimal dari obat ini memerlukan waktu paparan yang lebih lama dibandingkan dengan konsentrasi obat yang tinggi dalam darah (T > MIC). Penelitian ini bertujuan untuk mengkaji perbandingan penurunan kadar procalcitonin dan asam laktat pada pasien sepsis yang mendapat terapi antibiotik ceftriaxone rute intravena bolus dan rute intravena drip. Metode: Desain penelitian ini merupakan penelitian prospektif cohort, dengan analisa data menggunakan metode analisis komparatif tidak berpasangan. Pengamatan penanda infeksi procalcitonin dan asam laktat pada masing-masing kelompok dilakukan sebanyak tiga kali, yakni berupa data baseline, hari ke 3 dan 5 setelah terapi ceftriaxone diberikan. Hasil: Nilai rata-rata kadar procalcitonin dan asam laktat sebelum pemberian terapi ceftriaxone pada 15 pasien dengan rute intravena bolus adalah sebesar 23,50 ± 5,59 ng/ml dan 7,17 ± 1,3 mmol/L, sedangkan kadar procalcitonin dan asam laktat pada 15 pasien dengan pemberian ceftriaxone rute intravena drip adalah sebesar 12,98 ± 2,75 ng/ml dan 4,18 ± 1,2 mmol/L. Pada hari ke 3 setelah terapi diberikan, terjadi penurunan kadar procalcitonin dan asam laktat menjadi 14,18 ± 3,21 ng/ml dan 4,68 ± 1,1 mmol/L dengan rute pemberian intravena bolus, sedangkan pada kelompok rute intravena drip menjadi 9,78 ± 2,00 ng/ml dan 3,35 ± 1,7 mmol/L. Pada hari ke 5 setelah pemberian terapi ceftriaxone, kadar procalditonin dan asam laktat menurun menjadi 8,70 ± 2,54 ng/ml dan 2,39 ± 0,14 mmol/L dengan rute intravena bolus, sedangkan dengan rute intravena drip menurun menjadi 5,78 ± 1,38 ng/ml dan 2,85 ± 0,5 mmol/L. Namun, tidak ada perbedaan penurunan procalcitonin dan asam laktat yang bermakna antara kedua kelompok (p>0,05). Simpulan: Tidak terdapat perbedaan penurunan kadar procalcitonin dan asam laktat pada pasien dengan terapi ceftriaxone rute pemberian intravena bolus ataupun intravena drip. Kata kunci : ceftriaxone, intravena bolus, intravena drip, procalcitonin, asam laktat. Abstract Background : Ceftriaxone is a bactericidal group antibiotic and includes in the time dependent antibiotic class. The optimal bactericidal effect of this drug needs longer exposure time compared to high drug concentrations in the blood (T>MIC). This study aims to analyze procalcitonin and lactic acid levels in septic patients receiving therapy with ceftriaxone with an intravenous bolus and with intravenous drip route. Methods : This study is a prospective cohort design, data was analysed using unpaired comparative analysis methods. Observation of procalcitonin and lactic acid levels in each group were carried out three times involving baseline, day 3, and day 5 of ceftriaxone administration. Result : Before treatment, the average value of procalcitonin and lactic acid in 15 patients with ceftriaxone intravenous bolus therapy was 23,50 ± 5,59 ng/ml and 7,17 ± 1,3 mmol/L, whereas in 15 patients with intravenous drip route is 12,98 ± 2,75 ng/ml and 4,18 ± 1,2 mmol/L. On the 3rd and 5th day of ceftriaxone administration, there was a significant reduction (p < 0,05) of procalcitonin and lactic acid levels. There was no significant (p> 0,05) differences of procalcitonin and lactic acid levels between groups. Conclusion : There is no difference in the reduction of procalcitonin and lactic acid levels among those receiving ceftriaxone intravenous bolus nor intravenous drip administration. Key word : Ceftriaxone, intravenous bolus, intravenous drip, procalcitonin, lactic acid.

Hubungan Hemoglobin Terglikosilasi (HbA1c) Dengan Risiko Kardiovaskular Pada Pasien Diabetes Mellitus Hadian Widyatmojo; Lisyani Budipradigda Suromo
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar belakang : Diabetes Mellitus (DM) dengan kondisi hiperglikemik kronik dapat mengakibatkan gangguan sistem kardiovaskular dan peningkatan mortalitas. Hemoglobin terglikosilasi (HbA1c) merupakan salah satu parameter untuk pengendalian DM. Tujuan penelitian untuk membuktikan adanya hubungan antara kadar HbA1c serum dengan risiko kardiovaskular pada pasien DM. Metode : Penelitian belah lintang dilakukan pada 42 penderita DM yang dirawat di RSUP Dr. Kariadi Semarang periode Agustus - September 2017. Diagnosis DM didapatkan melalui rekam medis. Dilakukan pemeriksaan HbA1c dan dinilai faktor risiko yang terdapat pada rekam medis menggunakan skor interheart (IHR). Analisa statistik menggunakan uji korelasi Spearman. Hasil : Terdapat hubungan antara HbA1c dengan skor IHR dengan nilai r=0,887, p=0,001. Pasien dengan kategori risiko kardiovaskular tinggi memiliki nilai HbA1c dengan rerata 10,12 ± 2,29, skor kategori sedang 6,62 ± 1,67 dan skor kategori rendah 5,75 ± 0,78. Simpulan :Terdapat hubungan positif kuat antara HbA1c dengan risiko kardiovaskular pada pasien DM. Perlu dilakukan penelitian prospektif dengan sampel yang lebih besar. Kata kunci DM, HbA1c, Skor risiko Interheart

The association between adiponectin level and non alcoholic fatty liver disease (NAFLD) in obese adolescents Maria Mexitalia; Suci Romadhona
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Background: Non alcoholic fatty liver disease (NAFLD) has been associated with cytokines and inflammatory mediators. Adiponectin has insulin sensitizing effects and has correlation with severity of NAFLD disease. However, the study about the relationship between adiponectin level and NAFLD is lacking. The objective of the study was to determine the association between adiponectin level and NAFLD in obese adolescents through the role of insulin resistance. Methods: This was a cross-sectional study, that was done in August 2007. The inclusion criteria were obese adolescents aged 11-14 years, and normal weight adolescent as control group. Adiponectin was assessed by using ELISA, insulin resistance was obtained by Homeostasis Model Assessment Insulin Resistance (HOMA-IR). NAFLD was confirmed by abdominal ultrasound, which represented by fatty liver imaging. The comparison of adiponectin level and HOMA-IR among 3 groups were analyzed by Kruskal Wallis test, meanwhile the correlation between adiponectin level and some variables were analyzed by spearman correlation. Result: There were 73 subjects, consisted of 37 obese and 36 non obese. Among obese subjects, 54.1% got NAFLD. All of our obese subjects were insulin resistance, the HOMA-IR level of obese non NAFLD was 6.1 and obese with NAFLD was 6.8. The adiponectin levels in normal children was (5.1mg / ml), obese non NAFLD (4.1mg / ml) and obese with NAFLD (4.0 mg / ml) (p <0.001). There were no association between adiponectin level and other variables. Conclusion: There were significant differences of adiponectin levels and insulin resistance measured by HOMA-IR between normal and obese subjects, but no significant differences between the obese groups with or without NAFLD. Keywords: NAFLD, adiponectin, HOMA-IR, obesity, adolescent.

Hipertensi pada Pasien Kanker Kolorektal Metastatik dengan Terapi Bevacizumab di RSUP Dr. Kariadi Bayu Prio Septiantoro; Dyah Aryani Perwitasari; Imaniar Noor Faridah; Indra Pradipta
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar belakang: Kanker kolorektal saat ini sudah menjadi penyebab utama ketiga kematian akibat kanker di dunia, penyakit ini membutuhkan terapi yang progresif dimana salah satu terapinya adalah bevacizumab. Namun diketahui bevacizumab dapat menimbulkan hipertensi pada sebagian pasien. Penelitian ini bertujuan untuk untuk mengetahui onset terjadinya hipertensi akibat bevacizumab dengan rejimen kemoterapi apa yang digunakan. Metode: Penelitian ini merupakan sebuah tinjauan deskriptif restrospektif yang dilakukan di RSUP Dr. Kariadi, Semarang. Kriteria inklusi terdiri dari pasien kanker kolorektal metastatik yang berusia ? 18 tahun dengan hipertensi tingkat ?2 berdasarkan NCI CTCAE version 5.0 setelah diberikan terapi bevacizumab 5 mg/kg berat badan di RSUP Dr. Kariadi. Pengambilan data dalam 1 tahun (bulan April 2018 hingga April 2019) melalui peninjauan dari rekam medis, laporan penggunaan obat bevacizumab dan laporan penggunaan obat kardiovaskuler instalasi farmasi. Kriteria ekslusi dalam penelitian ini yaitu hipertensi tingkat ?2 berdasarkan NCI CTCAE version 5.0 yang muncul setelah ?4 kali waktu paruh bevacizumab (t 1/2 = 20 hari) dari kemoterapi yang terakhir. Hasil: Total 95 pasien sesuai kriteria, sebanyak 24 pasien (25,26%) teridentifikasi mengalami hipertensi tingkat ? 2 berdasarkan NCI CTCAE version 5.0. Dengan 20 pasien (83,33%) pasien mendapatkan kemoterapi rejimen FOLFOX4, sedangkan sisanya (16,66%) dengan rejimen de Gramont. Hipertensi ini muncul sebagian besar pada siklus III, diikuti siklus ke II, ke I dan ke VI. Tidak satupun pasien dengan kombinasi FOLFIRI yang terdeteksi mengalami hipertensi ini. Kesimpulan: Penelitian ini menunjukkan onset munculnya hipertensi tingkat ?2 NCI CTCAE version 5.0 paling banyak adalah pada siklus awal terapi yaitu I-III dan dengan rejimen kombinasi FOLFOX4 + bevacizumab. Kata Kunci: Kanker kolorektal, bevacizumab, hipertensi Background: Colorectal cancer nowadays is the third leading cause of cancer deaths in the world, this disease requires progressive therapy where one of the treatments is bevacizumab. But it is known that bevacizumab can cause hypertension in some patients. This study aims to determine the onset of the hypertension with chemotherapy regimen used. Method: This research is a retrospective descriptive review conducted at Dr. Kariadi General Hospital, Semarang. Inclusion criteria consisted of metastatic colorectal cancer patients aged ?18 years old with hypertension level ?2 based on NCI CTCAE version 5.0 after being given bevacizumab therapy dose 5 mg/kg body weight. Retrieval of data in 1 year (April 2018 to April 2019) through a review of medical records, reports on the use of bevacizumab drugs and reports on the use of cardiovascular drugs in Department of Pharmacy. The exclusion criteria in this study were hypertension level on NCI CTCAE version 5.0 which appeared after 4 times the half-life of bevacizumab (t 1/2 = 20 days) from the last chemotherapy. Result: Total 95 patients according to the criteria, 24 patients (25.26%) were identified as having hypertension level ? 2 based on NCI CTCAE version 5.0. With 20 patients (83.33%) patients received FOLFOX4 regimen, while the rest (16.66%) with de Gramont regimen. This hypertension occurs mostly in cycle III, followed by cycle II, to I and to VI. None of the patients with a combination of FOLFIRI. Conclusion: This research shows that the onset of hypertension level ?2 NCI CTCAE version 5.0 mostly in the initial cycle of therapy (I-III) with the FOLFOX4 + bevacizumab combination regimen. Keywords: Colorectal cancer, bevacizumab, hypertension

Hubungan Kadar Kreatinin Serum Dengan Kadar Mineral Pada Pasien Chronic Kidney Disease Diah Ayu Kusuma; Indranila Kustarini Samsuria
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Pendahuluan : Chronic Kidney Disease (CKD) merupakan gangguan fungsi ginjal yang irreversible, yaitu kemampuan tubuh gagal untuk mempertahankan metabolisme dan keseimbangan cairan dan elektrolit dan juga mineral. Sebagian besar proses metabolisme memerlukan dan dipengaruhi oleh elektrolit. Konsentrasi elektrolit mineral yang tidak normal dapat menyebabkan banyak gangguan . Saat fungsi ginjal semakin memburuk menjadi Stadium CKD 4 dan 5, ekskresinya cenderung berkurang dan tidak dapat dikompensasi. Tujuan penelitian ini adalah melihat pengaruh CKD pada mineral yaitu magnesium dan calcium. Metode : Penelitian ini adalah penelitian observasional retrospektif dengan pendekatan belah lintang (cross sectional) dengan melihat rekam medik pada senter tunggal di RSUP Dr. Kariadi Semarang selama periode 1 Januari 2017 – 31 Desember 2018 untuk kemudian dilihat hubungan pengaruh kadar kreatinin serum dengan magnesium dan calcium pada pasien CKD dengan terapi hemodialisis. Hasil dan pembahasan: Terdapat hubungan signifikan positif lemah antara kreatinin serum dengan magnesium (p=0,032, r= 0,327). Tidak terdapat hubungan antara kreatinin serum dengan kadar kalsium. Simpulan : Dari hasil penelitian dapat disimpulkan bahwa secara statistik terdapat hubungan yang bermakna antara kadar kreatinin serum dengan magnesium pada pasien Chronic Kidney Disease (CKD) dengan terapi hemodialisis. Kata Kunci Kreatinin, mineral, magnesium Chronic Kidney Disease, hemodialisis. ABSTRACT Introduction: Chronic Kidney Disease (CKD) is an irreversible kidney function disorder, which is the body's ability to fail to maintain metabolism and balance fluid and electrolytes and minerals. Most metabolic processes require and are influenced by electrolytes. Abnormal mineral electrolyte concentrations can cause many disturbances. When kidney function getting worse to stages CKD 4 and 5, the excretion tends to decrease and cannot be compensated. The purpose of this study is to look at the effect of CKD on minerals namely magnesium and calcium. Method: This study was a retrospective observational study with a cross sectional approach by looking at medical records at RSUP Dr. Kariadi Semarang during the period of 1 January 2017 - 31 December 2018 to see the correlation of influence of serum creatinine levels with magnesium and calcium in CKD patients with hemodialysis therapy. Results and discussion: There was a significantly weak positive correlation between serum creatinine and magnesium (p = 0.032, r = 0.327). There is no correlation between serum creatinine and calcium levels. Conclusion: The results of the study it can be concluded that there is a statistically significant correlation between serum creatinine levels with magnesium in Chronic Kidney Disease (CKD) patients with hemodialysis therapy. Keywords Creatinine, minerals, magnesium Chronic Kidney Disease, hemodialysis.

Pengaruh Terapi Spiritual Emotional Freedom Technique (SEFT) Terhadap Penurunan Tingkat Depresi Pada Pasien Kanker Serviks Sugih Wijayati; Suci Abrelia Fitriyanti; Arwani Arwani
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar Belakang: Reaksi psikologis yang dapat muncul setelah pasien didiagnosis kanker serviks pada umumnya merasa shock mental, takut, tidak bisa menerima kenyataan, sampai pada keadaan depresi. Depresi berdampak pada gangguan mood yang dikarakteristikkan dengan kesedihan yang intens, berlangsung dalam waktu lama, dan mengganggu kehidupan normal.Kondisi ini terjadi pada pasien kanker servix .Salah satu terapi komplementer yang dapat digunakan untuk menurunkan tingkat depresi pada pasien kanker servix yaitu terapi Spiritual Emotional Freedom Technique (SEFT).Salah satu dampak depresi yang akan muncul adalah lemahnya kondisi fisik yang akan menghambat proses pengobatan dan mendukung sel kanker servix semakin berkembang. Tujuan: untuk mengetahui pengaruh terapi SEFT terhadap tingkat depresi pada pasien kanker serviks di RSUD Dr. Moewardi Surakarta. Metode: Jenis penelitian ini adalah penelitian pra – eksperimental dengan desain penelitian pre and post-test without control group. Sampel dalam penelitian ini sebanyak 33 responden dengan teknik consecutive sampling. Uji analisis data dengan uji Wilcoxon – test. Hasil: Hasil penelitian menunjukkan penurunan skor depresi dari 28 (depresi sedang) menjadi 20 (depresi klinis) setelah dilakukan SEFT dan perubahan skor depresi secara statistik bermakna (p = 0,000). Kesimpulan: ada penurunan terapi SEFT terhadap tingkat depresi pada pasien kanker serviks. Kata kunci : depresi , SEFT, kanker serviks. Abstract Background : Psychological reactions commonly occur among cervical cancer patients are mental alteration, fear, denial and depression. Depression is a mood disorder characterized by prolonged sorrow, which can disrupt normal life. The SEFT therapy is an effective complementary therapy to reduce depression level. Aims: This study aims to examine the effect of SEFT therapy on depression among cervical cancer patients at Dr. Moewardi Surakarta General Hospital. Methods: A pre - experimental study using pre and post-test without control group design was applied to 33 respondents recruited by consecutive sampling method. The data were analyzed using the Wilcoxon test. Result: The depression score was decreased from 28 (moderate depression) to 20 (clinical depression) after intervention, which is statistically significant (p= 0.000). Conclusion : It is concluded that there is positive effect of SEFT therapy on depression level among cervical cancer patients. Keyword : depression, SEFT. Cervical Cancer.

Gambaran audiogram pada anak dengan penyakit ginjal kronis yang menjalani hemodialisis Muyassaroh Muyassaroh; Heru Muryawan; Nastiti Dwi Cahyani
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar belakang: Penyakit ginjal kronis (PGK) adalah kerusakan ginjal atau penurunan laju filtrasi glomerulus (GFR) kurang dari 60 mL / min / 1,73 m2 paling sedikit 3 bulan. Pasien PGK memiliki resiko kejadian kurang pendengaran yang tinggi. Tujuan: Mengetahui gambaran audiogram anak dengan PGK yang menjalani hemodialisis. Metode : Diskriptif retrospektif 7 kasus PGK ada anak yang menjalani hemodialisis di RSUP Dr.Kariadi Semarang Juli 2017. Hasil : didapatkan 5 kasus(71,4%) kurang pendengaran sensorineural, 1 kasus (14,3%) kurang pendengaran campuran (MHL) dan 1 kasus (14,3%) normal. Derajat kurang pendengaran bervariasi dari derajat ringan sampai sangat berat. Kesimpulan: Kurang pendengaran sensorineural sebagian besar terjadi pada anak dengan PGK yang menjalani hemodialisis. Kata kunci : Audiogram, SNHL, PGK Background: Chronic kidney disease (CKD) is kidney damage or a decrease in glomerular filtration rate (GFR) of less than 60 mL / min / 1.73 m2 for at least 3 months. Patients with CKD have a high risk of hearing loss. Objective: The aim of illustrate the audiogram on children with chronic kidney disease undergoing hemodialysis. Methode : Descriptif retrospective to seven cases of children with chronic kidney disease who undergoing hemodialysis in Karyadi hospital juli 2017. Result : Five cases (71,4%) with sensorineural hearing loss. One case(14,3%) showed severe mix hearing loss, one cases(14,3%) with normal audiogram. The degree of hearing loss from mild to profound Conclusion: Sensorineural hearing loss may occur in the majority of children with CKD on hemodialysis Keywords : Audiogram, SNHL, PGK

Tablet Hisap Dan Relaksasi Nafas Dalam Untuk Mengurangi Nyeri Tenggorok Pada Pasien Post Operasi Dengan General Anesthesia (GA) Arip Susianto; Hikmi Muharromah Pratiwi; Evi Komala Simamora
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar belakang: Standar prosedur penanganan pada pasien paska bedah di RSUP Dr Kariadi belum cukup efektif untuk mengurangi nyeri tenggorok paska operasi dengan pamasangan endotrakeal tube pada General Anesthesia (GA). Penggunaan tablet hisap terbukti mampu menurunkan nyeri tenggorok, akan tetapi bukti penelitian masih terbatas. Penelitian ini untuk menguji keefektivitasan pemberian tablet hisap dan relaksasi napas dalam untuk mengurangi derajat nyeri tenggorok paska operasi. Metode: Penelitian dilakukan dengan desain quasi experimental pre-posttest pada 11 Juli – 30 Oktober 2019. Subyek penelitian berjumlah 60 pasien paska operasi dengan general anesthesia yang dikelompokan menjadi 30 kelompok intervensi dan 30 kelompok kontrol. Nyeri tenggorok paska operasi diukur dengan menggunakan Visual Analogue Scale (VAS) pada 6 jam paska operasi dan dievaluasi tiap 12 jam selama 48 jam. Hasil: Perbedaan rerata skor VAS antara kelompok kontrol dan kelompok intervensi secara signifikan terjadi pada penilaian nyeri 36 jam paska operasi (t = -3,70, p = 0,002) dan 48 jam paska operasi ( t = -4,28, p = 0,000). Skor VAS pada kelompok intervensi lebih rendah secara signifikan dibandingan dengan skor VAS pada kelompok kontrol. Simpulan: Pemberian tablet hisap dan relaksasi napas dalam secara signifikan menurunkan tingkat nyeri tenggorak paska operasi. Pemberian tablet hisap dapat dijadikan sebagai intervensi alternatif untuk penangangan pasien dengan komplikasi nyeri tenggorok paska operasi. Key words: Nyeri tenggorok, Endotracheal Tube, Tablet hisap, Relaksasi napas dalam, Visual Analogue Scale (VAS) Background: The standard procedures of post operative patients at RSUP Dr Kariadi Semarang was ineffective to reduce post operative sore throat with Endotracheal Tube insertion in General Anesthesia. Lozenges was proven may reduce sore throat while the evidences were still limited. Methods: The research design was quasi experimental pre-post test on 11 july - 30 october 2019. The study subjects were 60 post operative patients with General Anesthesia grouped into 30 intervention grups and 30 control groups. Post operative sore throat was measured using Visual Analogue Scale (VAS) at 6 hours after surgery then evaluated every 12 hours for 48 hours. Results: Mean difference VAS score between intervention group and control group significantly in the assessment of pain 36 hours (t = -3,70, p = 0,002) and 48 hours ( t = -4,28, p = 0,000) post operatively. VAS score in intervention group was significantly lower than VAS score in control group. Conclusion: Lozenges and deep breath relaxation reduce significantly post operative sore throat. Lozenges could be used as an alternative intervention to treat patients with post operative sore throat. Keywords: Sore Throat, Endotracheal Tube, Lozenges, Deep Breath Relaxation, Visual Analogue Scale.

Prediction Score of Antegrade Chronic Total Occlusion Percutaneous Coronary Intervention Success in Dr. Kariadi Central General Hospital Semarang Anggit Pudjiastuti; Sodiqur Rifqi; Sefri Noventi Sofia
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Background: Lesion characteristics of chronic total occlusion (CTO) are predictors of percutaneous coronary intervention (PCI) success. A prediction score consist of these predictors can help CTO-PCI operators. Various prediction score had been established but none had been established in Indonesian population. Methods: This observational cohort study was performed in patients underwent native vessel CTO-PCI in Dr.Kariadi Hospital during 2018. Target vessels, ostial lesion, blunt stump, calcification, long lesion, bending, side branch, bridging collateral, and retrograde collateral were angiographic variables proposed to be predictors of CTO-PCI success. All of the variables were quantitatively assessed by two observers. Bivariate and multivariate analysis used to identify independent predictors of CTO-PCI success and to establish a scoring model. Results: A total 200 patients underwent CTO-PCI procedures were included to this study. All of the procedures used antegrade approach. The prediction score established as follows: bending (1 point), calcification (2 point), blunt stump (3 point), long lesion (1 point), and poor retrograde collateral filling (2 point). Total score ranged from 0 to 9 with decreased probability of success from 92.3% to 0.5%. Score value ? 3 categorized as difficult lesion with higher risk to failure compared to score value <3 (OR 15.4; p<0.001). The score model had good calibration and discrimination in predict CTO-PCI success (AUC 0.88; p<0.001). Conclusion: Bending, calcification, blunt stump, long lesion, and poor retrograde collateral were predictors of CTO-PCI success. The score consist of these variables could predict antegrade CTO-PCI success. Keywords: chronic total occlusion; percutaneous coronary intervention; success; prediction score.

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Location
Kota semarang,

Jawa tengah

INDONESIA

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Maya Nuriya Widyasari

Contact Email medica.hospitalia@yahoo.com

Phone -

Journal Mail Official medica.hospitalia@yahoo.com

Editorial Address -

Location Kota semarang, Jawa tengah INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Maya Nuriya Widyasari

Contact Email
medica.hospitalia@yahoo.com

Phone
-

Journal Mail Official
medica.hospitalia@yahoo.com

Editorial Address
-

Location
Kota semarang,

Jawa tengah

INDONESIA