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Journal of Pharmaceutical and Health Research
Published by Forum Kerjasama Pendidikan TInggi
ISSN : -     EISSN : 27210715     DOI : https://doi.org/10.47065/jharma.v3i1.1322
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Health Research memiliki bidang kajian, yaitu: 1. Bidang Gizi Klinis 2. Bidang Gizi Masyarakat 3. Pangan dan Gizi 4. Inovasi Pangan 5. Hematologi 6. Parasitologi 7. Biokimia 8. Laboratorium Kesehatan 9. Teknologi Laboratorium 10. Farmakologi 11. Farmasi 12. Keperawatan Jiwa 13. Keperawatan Anak 14. Keperawatan Maternitas 15. Keperawatan Medikal Bedah 16. Keperawatan Keluarga 17. Keperawatan Komunitas 18. Kesehatan Masyarakat 19. Teknologi Kesehatan
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "Vol 2 No 1 (2021): Februari 2021" : 5 Documents clear
Uji Skrining Fitokimia Ekstrak Etanol Daun Ubi Jalar Ungu (Ipomoea Batatas L.) Lidyawati Lidyawati; Sasmiati Farach Dita; Cut Melly Agustiany
Journal of Pharmaceutical and Health Research Vol 2 No 1 (2021): Februari 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (267.653 KB) | DOI: 10.47065/jharma.v2i1.778

Abstract

Purple sweet potato leaf (Ipomoea batatas L.) is one of the plants that has begun to be used as a traditional or herbal medicine. This study aims to determine the content of secondary metabolites from purple sweet potato leaves. This research was conducted at the Chemistry Laboratory, Faculty of Tarbiyah, State Islamic University of Ar-Raniry Banda Aceh with laboratory testing methods. Purple sweet potato leaves were extracted by maceration using 5 L 96% ethanol for 5 days and evaporated in a vacuum rotary evaporator to form a thick extract. Furthermore, phytochemical screening tests were carried out. The test results stated that purple sweet potato leaf extract contains Alkaloids (+++), Flavonoids (+), Tannins (+), Saponins (+), Terpenoids (+), and Steroids (+).
Formulasi Sediaan Sabun Padat Dari Ekstrak Kulit Pisang Awak (Musa Balbisiana) Secara Maserasi Rosa Mardiana; Yuniati Yuniati
Journal of Pharmaceutical and Health Research Vol 2 No 1 (2021): Februari 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (237.169 KB) | DOI: 10.47065/jharma.v2i1.779

Abstract

Indonesia is the largest producer of bananas, along with the high productivity of bananas, the amount of banana peel waste also increases. When harvesting bananas, banana peels, stems and leaves (about 80%) are only removed without further processing. This is what causes the potential for banana peel waste to be large enough so that it is necessary to overcome the banana peel so that it has good value. The content in banana peels include carbohydrates, protein, fat, calcium, iron, phosphorus, vitamins B, C and C. Banana peel also has a cellulose content of 14.4%, an abundant amount, especially from banana peels, can be used as an efficient product. The method used in this study used the maceration method where the banana peel extract (Musa balbisiana) was made in the form of solid soap. which is heated and then the application of oil which is directly reacted with an alkaline solution at a temperature of 50˚C, so that a soap base is obtained. The solid soap preparation tests carried out in this study were organoleptic tests, pH tests and foam stability tests. The results of the evaluation of the preparation showed that the soap preparation was solid, there was no change in shape and odor, and had a pH that was in accordance with the standards for skin.
Uji Efek Antifungi Ekstrak Daun Biduri (Calotropis Gigantea L.) Terhadap Pertumbuhan Jamur Trichophyton Mentagrophytes Safrida Safrida; Rosa Mardiana; Nurul Husna
Journal of Pharmaceutical and Health Research Vol 2 No 1 (2021): Februari 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (235.066 KB) | DOI: 10.47065/jharma.v2i1.787

Abstract

The leaf of biduri (Calotropis gigantea L.) is one of the plants that can be used as antifungal. Biduri leaves are used as antifungals based on the chemicals contained in them such as tannins, flavonoid saponins and polyphenols. The fungus Trichophyton mentagrophytes can cause a skin disease characterized by the appearance of circular and scaly patches or small bubbles known as Tinea or ringworm. This fungus has a habitat (especially in tropical and wet climates) in soil, humans and animals. This study aims to determine the effectiveness of biduri leaf extract (Calotropis gigantea L.) in inhibiting the growth of the fungus Trichophyton mentagrophytes and to determine what is the optimal concentration of biduri leaf extract (Calotropis gigantea L.) to inhibit the growth of the fungus Trichophyton mentagrophytes. This research was carried out at the Microbiology Laboratory of the Tarbiyah Faculty of UIN Ar-Raniry and the Chemical Laboratory of the Chemical Science Faculty, Syiah Kuala University, Banda Aceh, from 26 April to 21 August 2018. Biduri leaves were extracted using the maceration method which were soaked for 5 days with 2 repetitions and evaporated with using a rotary evaporator to obtain extract as much as 30 ml blackish green and thick. Inhibition test against the fungus Trichophyton mentagrophtes was carried out using the disc diffusion method on Potato Dextrose Agar (PDA) media with concentrations of 20%, 35% and 50%. Ketoconazole antifungal was made in suspension form as a positive control and aquadest as a negative control. The results showed that the diameter of the inhibition zone obtained from biduri leaf extract at a concentration of 50% of 9.16 mm was included in the medium category, at a concentration of 35% of 8.66 mm was included in the medium category, 20% concentration of 8.16 mm was included. in the medium category, 11.83 mm of ketoconazole suspension was included in the strong category and 0 mm of aquadest which had no inhibitory power.
Formulasi dan Uji Aktivitas Sediaan Masker Gel Peel Off Ekstrak Etanol 70% Daun Rambutan (Nephelium Lappaceum L.) Terhadap Propionibacterium Acnes Rahmawida Putri; Jaka Supriyanta; Dwi Afriliyani Adhil
Journal of Pharmaceutical and Health Research Vol 2 No 1 (2021): Februari 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (373.719 KB) | DOI: 10.47065/jharma.v2i1.836

Abstract

Rambutan Leaves (Nephelium Lappaceum L.) one of the plants that contain, alkaloids, flavonoids, tannins and saponins have antibacterial activity against Propionibacterium acnes which is a bacterium that causes acne. Rambutan leaf extract can be formulated to facilitate its use, one of which is in the form of a gel such as a peel off mask. This study aims to determine the characteristics of peel off mask preparations and to determine the antibacterial activity of ethanol extract 70% rambutan leaves (Nephelium Lappaceum L.) Peel off gel mask preparations 70% ethanol extract rambutan leaves (Nephelium Lappaceum L.) formulated into 4 formulas with a variety of extract concentrations, namely F1 (0%), F2 (10%), F3 (15%), F4 (20%). Physical evaluation tests which include: organoleptic, homogeneity, pH, viscosity, dry time, spreadability, adhesion, and irritation. And the antibacterial activity test was carried out against Propionibacterium acnes bacteria using the well method. The results showed that the physical evaluation was said to be good to meet the requirements. Antibacterial test results of gel peel off mask preparation of 70% ethanol extract of rambutan leaves (Nephelium Lappaceum L.) showed the existence of antibacterial activity against Propionibacterium acnes bacteria inhibition was the best at the concentration of F4 (20%) with an average diameter of 10.03 mm. One way ANOVA analiysis result showed that there wewre significant differences in each formula group (p<0,05).
Formulasi dan Evaluasi Fisik Sediaan Gel Antiseptik Tangan Dari Ekstrak Etanol 96% Daun Pandan Wangi (Pandanus Amaryllifolius Roxb) Siti Marina; Banu Kuncoro; Sofi Nurmay Stiani; Rahmawida Putri
Journal of Pharmaceutical and Health Research Vol 2 No 1 (2021): Februari 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (322.168 KB) | DOI: 10.47065/jharma.v2i1.837

Abstract

Antiseptic serves to kill or inhibit the growth of bacteria that can cause the onset of disease. Antiseptics can be formulated with natural ingredients so that they are environmentally friendly. Pandan wangi leaf is a plant that is often used as a food additive leaves, as a green dye and aroma. Pandan fragrance is also one of the plants that can be used as antiseptic formulations because it has antibacterial activity and can be used as a topical preparation in the form of gels. The aim of this research is to know the difference of pandan wangi leaf extract concentration (Pandanus amaryllifolius Roxb.) Which has optimum physical properties evaluation. This research is an experimental research, maseration method used to get extract with 96% ethanol. The gel was formulated into four formulas with various extract concentrations of 10%, 20%, 30%, and 40%. Evaluation tests include: organoleptic, homogeneity, pH, dispersion, viscosity, stability, hedonic, irritation and hand antiseptic testing. The results showed that the concentration of extract had no effect on pH and homogeneity. Increased concentration of extract effect on the color change and aroma. The higher concentration of extract will be more concentrated also color. The result of stability inspection showed that texture change in F2 and aroma change in F3. A good gel preparation formula based on physical quality and hedonic test is a concentration formula of 10% (F1). Keywords: Pandanus amaryllifolius Roxb., Hand Antiseptic, Gel.

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