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INDONESIA
Journal of Pharmaceutical and Health Research
Published by Forum Kerjasama Pendidikan TInggi
ISSN : -     EISSN : 27210715     DOI : https://doi.org/10.47065/jharma.v3i1.1322
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Health Research memiliki bidang kajian, yaitu: 1. Bidang Gizi Klinis 2. Bidang Gizi Masyarakat 3. Pangan dan Gizi 4. Inovasi Pangan 5. Hematologi 6. Parasitologi 7. Biokimia 8. Laboratorium Kesehatan 9. Teknologi Laboratorium 10. Farmakologi 11. Farmasi 12. Keperawatan Jiwa 13. Keperawatan Anak 14. Keperawatan Maternitas 15. Keperawatan Medikal Bedah 16. Keperawatan Keluarga 17. Keperawatan Komunitas 18. Kesehatan Masyarakat 19. Teknologi Kesehatan
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 38 Documents
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Identifikasi Formalin Pada Ikan Segar di Pelabuhan Pendaratan Ikan Idi Rayeuk Kabupaten Aceh Timur Mardiana, Rosa; Lidyawati, Lidyawati; Zulfikri, Muhammad
Journal of Pharmaceutical and Health Research Vol 1 No 3 (2020): Issue Oktober 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

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Abstract

Indonesia is the second largest country after China in terms of capture fisheries production. Capture fisheries production in Indonesia in 2016 reached 6.83 million tons with a value of Rp. 125.3 trillion. The abundant fishery potential causes the fish preservation process at the fishermen level to be constrained. The limited number of preservatives that are safe for food makes formaldehyde an alternative preservative. The use of formaldehyde in food can cause poisoning to the human body.In the formaldehyde test conducted by the Integrated Supervision Team of the Aceh Marine and Fisheries Service (DKP) in 2017 it was found that the practice of using formalin as a fish preservative was still used by some fishermen and fish traders in Indonesia. Aceh. This research was conducted to determine the sustainability of the practice of using formaldehyde by fishermen and traders by identifying the formalin content in tuna and mackerel in Idi Rayeuk Fish Landing Port, East Aceh Regency. The samples used in this study were 3 tuna and 3 mackerel fish taken randomly at the Idi Rayeuk Fish Landing Site, East Aceh. The results showed that all samples tested showed negative results or the fish did not contain formaldehyde. This shows that the public and fishermen's awareness of the dangers of formaldehyde is very good.
Aktivitas Antibakteri Sediaan Gel dari Fraksi Aktif Daun Sintrong (Crassocephalum Crepidioides (Benth) S Moore) Saputri, Muharni; Mierza, Vriezka
Journal of Pharmaceutical and Health Research Vol 1 No 3 (2020): Issue Oktober 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

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Abstract

Indonesia is a tropical country that allows bacteria to easily grow and develop, especially in the skin. The drugs used are very diverse, generally from corticosteroids, which have side effects. This encourages the need for research on antimicrobial drugs from natural ingredients such as herbs that have high potency and relatively low side effects. Sintrong plants (Crassocephalum crepidioides (Benth.) S. Moore) are found in Parmeraan Village, Dolok District, North Padang Lawas Regency, North Sumatra Province. This plant is thought to contain alkaloid compounds and tannins as antimicrobials. This research method is an experimental study with the maceration method of ethanol extract and fractionation of n-hexane, ethyl acetate, phytochemical screening, making topical gels 20%, 10%, and 5% with parameters of pH, homogeneity, viscosity, dispersibility and adhesion as well as Antibacterial test against pure cultured bacteria using agar diffusion method using metal buffer, the bacteria used were gram-positive bacteria (Staphylococcus aureus ATCC 29737) and gram-negative bacteria (Escherichia coli ATCC 10536). The results showed that the ethanol extract of Sintrong leaves can be formulated in the form of a gel. The results of the evaluation that have been carried out on the methanol extract gel of Sintrong leaves show that the preparation has met the gel requirements. The formula that has the best antibacterial activity is Formula 1 which provides an inhibitory diameter of 17.10 mm and 18.75 mm for Escherichia coli and Staphylococcus aureus bacteria.
Faktor–Faktor Yang Berpengaruh Terhadap Kejadian Asma Bronkial Pada Anak di Puskesmas Saitnihuta Kabupaten Humbanghasundutan Winta, Winta; Fransiska, Fransiska; Nova, Nova
Journal of Pharmaceutical and Health Research Vol 1 No 3 (2020): Issue Oktober 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

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Abstract

The prevalence of asthma in Indonesia above <1 year 1.1%, Asthma causes a loss of 16% of school days in children. To determine the factors that affect the incidence of bronchial asthma in children. Asthma is a condition in which the airway is narrowed due to hyperactivity to certain stimuli that cause inflammation. The research method used case control study method. The diagnosis of asthma is based on anamnesis, clinical signs, additional examination. The control group were children who were not found to have asthma based on anamnesis, clinical signs, additional examination by pediatricians. The data were analyzed by univariate, bivariate, and chi square test. The result of research of risk factors influencing the incidence of asthma are sex (OR = 8,25, 95% CI, 1,252-54,364; p = 0,028), pet ownership (OR = 30,65; 95% CI; 1,538-610; (OR = 19.27; 95% CI: 2,169-171,3; p = 0.008), family illness history (OR = 8,27; 95% CI; 1,505-45,434; p = 0.015), cigarette smoke (OR = 23,13; 95% CI; 4,141-129,2; p = <0.001). The probability of individuals for bronchial asthma with all risk factors was 46.51%. Risk factors that affect the incidence of bronchial asthma are gender, pet ownership, climate change, family history, cigarette smoke. Suggestion for the public to be vigilant if any occurrence of shortness of breath to immediately contact health officer for further management.
Analisis Natrium Siklamat Dalam Minuman Tebu(Saccharum Officinarum, L) Secara Spektrofotometri Lidyawati, Lidyawati; Mardiana, Rosa; Rejeki, Dwi Putri; Jauhari, Jauhari
Journal of Pharmaceutical and Health Research Vol 1 No 3 (2020): Issue Oktober 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

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Abstract

Sodium Cyclamate is one type of sweetener that is permitted, although being allowed to use excess sodium cyclamate can lead to cancer formation. Long-term consumption of sodium cyclamate can lead to metabolism of sodium cyclamate into cyclohexilamine compounds. The purpose of this study was to determine how much sodium cyclamate is used, whether it exceeds the maximum limit of 500 mg / kg weight of the material that has been determined. The sample used was a sample of sugarcane juice sold in Darussalam, which was then examined at the Chemical Laboratory of UIN Ar-raniry and FKIP Kimia Unsyiah Banda Aceh. The analytical method used is quantitative analysis using the UV-vis spectrophotometry method to determine the sodium cyclamate level. The results showed that the 4 samples used were negative containing sodium cyclamate with the level of Sample I = -449.8 Sample 2 = -426.4 Sample 3 = -520.6 Sample 4 = -444.8.
Pengaruh Pengetahuan dan Sikap Terhadap Kepatuhan Minum Obat Pada Penderita TB Paru Ardat, Ardat
Journal of Pharmaceutical and Health Research Vol 1 No 2 (2020): Issue June 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

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Abstract

One type of generative disease that has been infected for a long time amid Indonesian society, which attacks the productive age group and children and is the number one killer infectious disease. Non-compliance with taking the medication regularly for TB sufferers can hinder the achievement of cure rates. The magnitude and extent of the problems caused by pulmonary TB require all parties to be able to commit and cooperate in the prevention of pulmonary TB. The purpose of this study is to determine the influence of knowledge and attitudes towards adherence to taking medication. The research design is a Cross-Sectional Study with an observational approach. The sample in this study were 39 people with pulmonary TB data collection instruments using a questionnaire. Data analysis with Che-Square analysis. The results of the study found that knowledge and attitudes had an effect on the value of p = 0,0001 and attitude had an effect on the value of p = 0.004. The conclusion of adherence is strongly influenced by the behavior and habits of one of them is knowledge
Penerapan Komputer Dalam Mengidentifikasi Virus dan Bakteri Penyakit Ichtyosis Menerapkan Algoritma Rete Sanjaya, Thomas
Journal of Pharmaceutical and Health Research Vol 1 No 2 (2020): Issue June 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

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Abstract

Most people use it not only for commercial purposes, but also to obtain information on the detection of diseases quickly and efficiently with computer-based applications that can help the general public to find out the causes and symptoms of the disease. For this reason, we need a system designed to be able to imitate the expertise of an expert in answering questions and solving a problem in accordance with the knowledge of an expert that is entered into a computer system. The development of artificial intelligence technology that occurred has enabled expert systems to be applied in detecting diseases using programming languages. One of them is in providing information about various problems, especially hepatitis. The expert system method used is the Rete Algorithm used to deal with uncertainty in the diagnosis of ichthyosis. With the facilities provided for the user, allowing users to use this system according to their individual needs. Users are given the ease of knowing information about the symptoms of ichthyosis, and its prevention.
Penerapan Metode Certainty Factor Dalam Mendiagnosa Penyakit Skizofrenia berbasis Komputer Silaban, Cynthia
Journal of Pharmaceutical and Health Research Vol 1 No 2 (2020): Issue June 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

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Abstract

Current technological developments are very rapid, so the development of these technologies is very beneficial in all fields including health. In today's case there are a lot of things that are detrimental to others even yourself. Where the case can occur self-harm to the loss of level of awareness in controlling emotions. The purpose of this study is to diagnose schizophrenia and provide solutions to the conditions experienced through the application of an expert system. Certainty Factor method can provide ease in making diagnoses and provide more accurate diagnoses based on previous events and can be revised again in solving new problems
Analisis Kemampuan Petugas Penyuluh Lapangan Keluarga Berencana (PLKB) Dalam Melaksanakan Program Kependudukan Keluarga Berencana dan Pembangunan Keluarga (KKBPK) di Kabupaten Tapanuli Utara Tahun 2018 Simanjuntak, Irmauli; Nugraha, Tarsyad; Simanjorang, Asyiah
Journal of Pharmaceutical and Health Research Vol 1 No 2 (2020): Issue June 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

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Abstract

Family Planning Program (KB) is one of the basic social programs that are very important for the progress of a nation. The National Family Planning Program has been inseparable from the role of Planning Field Planners (PLKB) officers. The success of the PLKB in carrying out their duties is supported by their ability in mastering the National Family Planning Program in the face of changing environmental conditions. Objectives; to determine the ability of PLKB officers and efforts to improve the capacity of the PLKB in implementing KKBPK programs in North Tapanuli Regency. Method; The research design used in this study is a combination of quantitative and qualitative methods (mixed method). The samples in this quantitative research is that all PLKB in North Tapanuli Regency are 26 PLKB people. The informants for the qualitative research were PLKB in Simangumban District, North Tapanuli Regency as the main informants and Head of Division, Head of Program Sub-Division and Planning of PPKBP3A Office, and the Village Head as triangulation informant. Data analysis used is univariate and bivariate analysis with chi square statistical test for quantitative research and data reduction stages, data display, and conclusionorverification. Results; that the p-value of the knowledge variable was 0.000 <0.05 and the p-value for the attitude variable was 0.003 <0.05. Conclusion; there is a relationship between knowledge and attitudes with the ability of the PLKB officers to implement the KKBPK program in North Tapanuli District in 2018
Formulasi Sediaan Krim Menggunakan Kolagen Tulang Itik Serati (Cairina Moscahta) Sebagai Anti Aging Zebua, Nilsya Febrika; Anggraini, Nurul; Sudewi, Sudewi
Journal of Pharmaceutical and Health Research Vol 1 No 2 (2020): Issue June 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

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Abstract

At the age of 30, humans lose about 15-20% of collagen and at the age of 40, humans no longer produce collagen, so additional collagen is needed from outside the body. Serati duck bone (Cairina moschata) has not been treated yet and is a waste. This study aims to determine the presence of collagen content in serati duck bones (Cairina moschata) and to formulate serati duck collagen in cream preparations as anti-aging. This study used an experimental method, using serati duck test material (Cairina moschata). Stages of research include extraction of collagen from serati duck bone (Cairina moschata), characterization of collagen with Infrared Spectrophotometry, manufacturing of serati duck bone collagen cream (Cairina moschata) with concentrations of 1%, 1.5%, 2.5%, 3.5% and evaluation of collagen cream preparations. The results showed that the serati duck bone (Cairina moschata) contained collagen at wave numbers 2920-3280 cm-1 and 1270 - 1630 cm-1 indicating the presence of amine and amide groups. Serati duck collagen can be formulated into an oil-emulsion (M / A) type of cream emulsion with the results of evaluation of the preparation is a homogeneous and stable preparation for 12 weeks of storage, does not irritate the skin, and the pH range of 6.0 to 6.3. Statistical test results show a probability smaller than 0.05. The results of the test of anti-aging cream preparations on the face showed changes in large pores to small, changes in many blemishes to a little and changes in wrinkled skin to become wrinkled. Anti aging cream preparations have shown a significant increase in effect every week for a month using this anti aging cream
Formulasi Sediaan Krim Menggunakan Kolagen Tulang Ikan Patin (Pangasius sp.) sebagai Anti Aging Sudewi, Sudewi; Zebua, Nilsya Febrika; Sari, Shelva Filiana
Journal of Pharmaceutical and Health Research Vol 1 No 2 (2020): Issue June 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

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Abstract

Patin fish (Pangasius sp.) is a fish that has been cultivated by many people because it has a high content of omega 3. People consume patin fish meat as a source of protein, while patin fish bones are only disposed of as waste. Collagen is a protein derivative that has the effect of maintaining skin elasticity. This study aims to determine whether the patin fish bones contain collagen and is there an influence of the use of anti-aging collagen patin fish bone cream on the results of changes in facial skin care. Collagen characterization using infrared spectrophotometry and formulated into cream preparations with concentrations of 1%, 1,5%, 2,5%, 3,5% and evaluation of preparations include homogeneity test, pH measurement, emulsion type determination test, stability test, skin irritation to volunteers and anti-aging effectiveness test. The results showed that patin fish bones contained collagen at wave numbers 3250-3350 cm-1 and 1260-1630 cm-1 which indicated the presence of amine and amide groups. The use of patin fish collagen cream affects the changes in texture, wrinkles, moisture, blemishes and pores become smoother. The best formulation is the formula that contains 3,5% of patin fish bone collagen

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