cover
Contact Name
Rachmat Hidayat
Contact Email
hanifmedisiana@gmail.com
Phone
+6281949581088
Journal Mail Official
journalnaset@gmail.com
Editorial Address
Jl. Sirna Raga no 99, 8 Ilir, Ilir Timur 3, Palembang, Sumatera Selatan, Indonesia
Location
Kota palembang,
Sumatera selatan
INDONESIA
Natural Sciences Engineering and Technology Journal
Published by HM Publisher
ISSN : -     EISSN : 28072820     DOI : https://doi.org/10.37275/nasetjournal
Natural Sciences Engineering and Technology Journal (NASET Journal) concern with publishing the original research articles, review articles from contributors, and the current issues related to engineering, technology, and natural sciences. The main objective of NASET Journal is to provide a platform for international scholars, academicians, and researchers. It also aimed to promote interdisciplinary technology studies in Informatic Engineering, Electronica Engineering, Civil Engineering, Informatic System, Computer System, Architecture, and Natural Sciences in the world.
Arjuna Subject : Umum - Umum
Articles 37 Documents
Predesign of Biphenyl Chemical Factory from Benzene with Capacity of 10.000 Ton Per Year Roman Robiati
Natural Sciences Engineering and Technology Journal Vol. 1 No. 1 (2021): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v1i1.1

Abstract

Biphenyl is one of the most important supporting materials needed in the chemical industry as an intermediate. This study aimed to describe the technical review of the biphenyl plant design to be built in Gresik, East Java. The predesign process of the biphenyl plant consists of the analysis of the location of the factory, analysis of the benzene process, and analysis of utility calculations. The factory is designed to operate continuously for 330 days, 24 hours per day, and requires 214 employees. The manufacture of biphenyl begins by reacting benzene in a pipe flow reactor (R-01) at a reactor temperature of 377ºC and a pressure of 2 atm. Economic analysis shows that the value of ROI before tax is 50.38%, and the value of ROI after tax is 32.75%. POT before tax is 1.65 years, and POT after tax is 2.34 years. The BEP value is 43.11%, and the SDP value is 23.75%. The interest rate in DCF for 10 years averages 19%. In conclusion, a biphenyl plant from benzene with a capacity of 10,000 tons/year is worth considering from a technical and economic point of view.
Redesigning the Patiayam Kudus Archaeological Museum with a Regionalism Architecture Approach Muhammad Sulthon
Natural Sciences Engineering and Technology Journal Vol. 1 No. 1 (2021): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v1i1.2

Abstract

Regionalism architecture is architecture that advocates the appearance of buildings that are the result of a compound of internationalism with modern cultural and technological patterns, values, and nuances of tradition that are still adhered to by the local community. This study aimed to describe the redesign of the Patiayam archaeological museum, which is better able to collect, accommodate, maintain, and exhibit as a whole the prehistoric relics found at the Patiayam Site. This research is descriptive research. This method describes, and explains the design requirements and design determinants of the planning and design of the Patiayam Archaeological Museum, Kudus, Central Java. The style of the house building joglo Kudus as a form of local architectural style will become the basic idea of regionalism architecture in the design of the Patiayam Kudus museum. The shape of the façade of the main museum building adopts the typical shape of the traditional joglo Kudus house but has undergone changes in the development of detailed forms due to the difference in the size scale of the joglo Kudus house and the museum building, which is larger in size. In conclusion, the architectural concept of regionalism increases the functionality of the Patiayam Kudus archaeological museum as a means of educating about ancient sites.
Ethics in Gene Editing: A Narrative Literature Review I Made Diana
Natural Sciences Engineering and Technology Journal Vol. 1 No. 1 (2021): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v1i1.3

Abstract

Gene editing is the process of making precise, intentional changes to the DNA sequence of an organism, including humans, animals, and plants. However, there are always ethical questions to address, especially when the manipulation involves the human genome. This literature review aimed to describe the ethics of gene editing and its application. There is currently an urgent need to actively pursue those conversations as commercial gene sequencing and editing technologies have become more accessible and affordable. Gene editing has enormous potential both as a research tool and a therapeutic intervention. While other types of gene editing are relatively uncontroversial, gene editing has been strongly resisted. In conclusion, gene editing research can be conducted safely in ways that carry manageable and reasonable risks.
Genetics in Colorectal Cancer: A Narrative Literature Review Billy Peter Manawan
Natural Sciences Engineering and Technology Journal Vol. 1 No. 1 (2021): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v1i1.4

Abstract

Colorectal cancer (CRC) is the third most commonly diagnosed form of cancer globally, which is about 11% of all cancer diagnoses. Obesity, together with kind of sedentary lifestyle, red meat consumption, tobacco, and alcohol consumption are considered as predisposing factors of progression of CRC. This literature review was aimed to describe genetic aspect in colorectal cancer. In the development of colorectal cancer, genetic factors having a role in its incidence. The hereditary type of colorectal cancer was divided into two types is polyposis and Lynch syndrome which have each and different mechanism and genetic pattern. Lynch syndrome contributes to 3–5% of CRC cases and is caused by a germline mutation in one of four genes associated with the DNA mismatch repair (MMR) system; MLH1, MSH2, MSH6, or PMS2. In polyposis, there are some types such as familial adenomatous polyposis (FAP) which is mostly caused by APC mutation, MYH-associated polyposis, and the rare hamartomatous polyposis syndromes. In conclusion, genetic testing and better family history documentation can enable those with a hereditary predisposition for the neoplasm to take preventive measures.
Genetic Variants of Butyrylcholinesterase and Their Potential Impact on Human Health: A Narrative Literature Review Bharmatisna Anggaharsya Nugraha
Natural Sciences Engineering and Technology Journal Vol. 1 No. 1 (2021): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v1i1.5

Abstract

Butyrylcholinesterase (BChE) is an enzyme found in plasma and many other parts of the body. It is an enzyme that hydrolyses drugs containing ester bonds, such as drugs acting at the neuromuscular junction and local anaesthetic agent. This literature review aimed to describe genetic variants of butyrylcholinesterase. BChE polymorphisms have been shown to produce enzymes with varying levels of catalytic activity. Analysis of butyrylcholinesterase involves the determination of both enzyme activity and biochemical phenotypes. Phenotype is determined by the use of specific enzyme inhibitors (such as dibucaine or fluoride) that produce phenotype-specific patterns of dibucaine or fluoride numbers. Molecular genetic analyses can determine the true genotypes. In conclusion, genetic variants of human butyrylcholinesterase were one of the first examples in the new field of pharmacogenetics when it was recognized that abnormal response to succinylcholine was due to a mutated enzyme with low binding affinity.
Enzyme-Linked Immunosorbent Assay (ELISA): A Narrative Literature Review Maya Chandra Dita
Natural Sciences Engineering and Technology Journal Vol. 1 No. 2 (2021): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v1i2.6

Abstract

Enzyme immunoassay (EIA) and enzyme-linked immunosorbent assay (ELISA) are both widely used as diagnostic tools in medicine and as quality control measures in many industries. This literature review was aimed to describe enzyme linked immunosorbent assay in practical. ELISA has been the system of choice when testing soluble antigens and antibodies. EIA/ELISA uses the basic immunological concept of antigen binding to specific antibodies, which allows the detection of small amounts of antigens such as proteins, peptides, hormones or antibodies in fluid samples. In all protocols, solid-phase reagents are incubated with secondary or tertiary reactants covalently coupled with the enzyme. The unbound conjugate is washed and a chromogenic or fluorogenic substrate is added. In conclusion, EIA / ELISA is a powerful method not only for general biomedial research but also as a diagnostic tool. This procedure allows the detection of all types of biological molecules at very low concentrations and quantities. Despite their limitations, EIA/ELISA remains an important tool in both clinical and basic research, and in clinical diagnosis.
Polymerase Chain Reaction Technique: Overview and Evolution Uses Arpian Herponi
Natural Sciences Engineering and Technology Journal Vol. 1 No. 2 (2021): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v2i2.7

Abstract

Polymerase chain reaction (PCR) is a laboratory technique used to amplify or create multiple copies of a specific segment of DNA. This literature review aimed to describe the overview and uses of polymerase chain reaction techniques in biomolecular science. There are two principal regions of PCR usage in bioscience. They are high-throughput PCR frameworks and microfluidics-based PCR gadgets for purpose-of-care (POC) applications. In conclusion, the effective PCR enhancement of GC-rich DNA groupings addresses another test. It is confounded by the generation of auxiliary constructions impeding full denaturation and preliminary tempering and addresses numerous procedures to beat this issue that has been set up.
DNA Isolation: A Method for Improving the Efficiency of DNA Extraction from Clotted Blood Samples Bobby Rianto Adi Putra
Natural Sciences Engineering and Technology Journal Vol. 1 No. 2 (2021): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v2i2.8

Abstract

In general, the genome research of high DNA extraction from clotted blood produced a low quality. The aim of this study is to develop a simple and safe technique for dispersing blood clots with ball-bearing metal shots. A total of 31 clotted blood samples were randomly selected as part of the Mashhad Stroke and Heart Atherosclerotic Disorders (MASHAD) study. Ten milliliters of peripheral blood were collected in plain tubes. Samples were spun, and the serum was separated. All tubes containing clotted blood were stored at −80°C. Another 32 samples of clotted blood from this cohort were chosen and considered as a comparator group. The yield and purity of DNA obtained by the three steps were significantly different (P < 0.0001), with a higher yield in the modified salting-out method. In conclusion, the salting-out method is simple, efficient, and economical for DNA isolation from old clotted blood samples.
Analysis of the Motor Control System for Moving Goods Using Google Assistant Dimas Setiawan
Natural Sciences Engineering and Technology Journal Vol. 1 No. 2 (2021): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v1i2.9

Abstract

Developments in robotics science have positive impact in the industrial sector. One example is the process of moving an item/object from one place to another. This study aimed to test the motion system, namely a DC motor that functions as a motor for carrying goods. The method used is input from commands given by the user via a smartphone with voice access. As an intermediary, a bluetooth connection is used so that commands can be sent from a smartphone to the control circuit. The controller used is the AVR type, namely atmega 328 on the Arduino Uno board. At the output, there are relays and current amplifiers that function as motor drivers. The user will give orders via a smartphone where on the smartphone runs an application, namely a voice to text converter. The application will convert the human voice into text and send via bluetooth to the controller. The Arduino controller will identify the command code and execute it, namely controlling the robot's motion in the direction desired by the user, for example forward, backward left and right or towards a predetermined point. In conclusion, the analysis of the drive motor control system was successfully carried out by calculating and measuring the power of the DC motor. The control system program was successfully created in C language using arduino. The program successfully runs and controls the motor motion properly according to the user's command via the Google assistant.
Design and Build Security for Open and Close System of House Fence Using a Microcontroller-Based Remote Control Nashrullah Mujibur Rahman; Didik Tristianto; Slamet Winardi
Natural Sciences Engineering and Technology Journal Vol. 1 No. 2 (2021): Natural Sciences Engineering and Technology Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/nasetjournal.v1i2.10

Abstract

Home security is an inevitable need. The security system on the fence by entering a password on the remote control allows ensuring security. This study aimed to design a security system technology that is automated when the homeowner enters a pre-set password/passcode. All of these systems are connected to the ATmega8535 microcontroller which has been programmed using the Code Vision Avr software stored in the ATmega8535 microcontroller memory and supporting memory as a means of storing password data. In conclusion, the security design of opening and closing the house fence with a remote control based on a microcontroller increases the security of the home environment.

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