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Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)

jetromi
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Published by TALENTA PUBLISHER

ISSN : 26860872 EISSN : 26860856 DOI : 10.32734

Core Subject : Health, Science,

Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Journal of Endocrinology, Tropical Medicine and Infectious Diseases (JETROMI) is an international peer-reviewed journal (February, May, August and November) published by TALENTA Publisher, Universitas Sumatera Utara and managed by Faculty of Medicine, Universitas Sumatera Utara. It is dedicated to interchange for the articles of high quality research in the field of Medical Science. The journal publishes state-of-art papers in fundamental theory, case report, experiments and simulation, as well as applications, with a systematic proposed method, sufficient review on previous works, expanded discussion and concise conclusion. As our commitment to the advancement of science and technology, the JETROMI follows the open access policy that allows the published articles freely available online without any subscription. Each publication contains 6 (six) research articles which will be published online.

Arjuna Subject : Kedokteran - Endokrinologi, Diabetes dan Metabolisme

Articles 86 Documents

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Characteristics of Lung Cancer Patients in Haji Adam Malik General Hospital Medan in 2016-2018 Satthiyabalan Sivabalan Logawathi; Causa Trisna Mariedina
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 1 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Lung cancer is a malignant disease in the lung where abnormalities caused by collection of genetic changes in the epithelial cells of the airway, which lead to cell proliferation that cannot be controlled. This study was conducted to determine the characteristics of lung cancer patients in Haji Adam Malik General Hospital Medan in 2016-2018. This research is a descriptive study with a case series approach. The study population was 311 lung cancer patients using Total Sampling method. The tendency of inpatient lung cancer patients visiting H. Adam Malik General Hospital Medan in 2016-2018 has decreased. The highest proportion of patients with lung cancer based on sociodemography obtained 65-69 years old age group, men with 3: 1 sex ratio, work of farmers, living outside the city of Medan, the main complaint was more than one complaint, had a history of smoking, no pleural effusion occurred, the type of adenocarcinoma histology and the method of taking a cytological fluid specimen. There was a statistically significant relationship between age with sex, sex with occupation, sex with smoking history, occupation with primary complaints, occupation with smoking history, and histology type by specimen collection and there rest have no statistically significant difference.

The Correlation of Santri’s Personal Hygiene to the Incidences of Scabies in Pesantren Al-Kautsar Simalungun (a boarding school) Fanissa
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 1 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background. Scabies is a skin disease caused by the parasite named Sarcoptes scabiei. Scabies commonly found in developing countries, including Indonesia. There is a high prevalence of scabies in children and adolescents. Scabies is an infectious disease influenced by either the presence or absence of risk factors for scabies in each individual. Scabies often occurs among people who live together. Objectives. This study intends to see whether there is an influence of personal hygiene behavior on the incidence rate of scabies. Method. This study is an observational analytic study with a cross-sectional design. Primary data were used in this study. The data were collected by doing history-taking, physical examination, as well as conducting ink tests on lesions on the patient's body to observes scabies, and interviews/questionnaires to observes personal hygiene behavior. The samples were chosen by a simple random sampling method. The data that has been collected will be analyzed using the fisher’s exact statistical test. Results. There are 91 respondents, including 39 men and 52 women with the age range of 12-15 years. Forty eight respondents (52,7%) are diagnosed scabies, 74 respondents (81,3%) have good personal hygiene, 17 of them (18,7%) have a bad personal hygieneConclusion. There is a significant correlation between personal hygiene and the incidence of scabies with p value of 0,001.

STI Co-infection Among HIV/AIDS Patients at H. Adam Malik General Hospital, Medan, Indonesia Safirah Khairuna
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 2 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Both HIV/AIDS and Sexually Transmitted Infection (STI) are transmitted through sexual activites making a parallel port of entry making the two condition increase the each other’s transmission which results as an impact to progression of HIV infection. This study aims to determine the characteristics of HIV/AIDS patients co-infected with sexually transmitted infections in H. Adam Malik General Hospital Medan between 2017 and 2018. This study is a descriptive observational study of 2422 HIV/AIDS patients attending H. Adam Malik General Hospital. Of those, 62 patients were diagnosed with STI coinfection. The majority of patients were male (85,5%) aged within the group of 25 – 49 years old (80,6%), had the level education of high school (88,7%), mostly were entrepreneurs (50%), and were single (59,7%). Most of the patients were already in their Stadium III (80,6%) clinical stage and had CD4+ count < 200/mm3 (51,6%). Condyloma acuminatum (35,5%) was found as the most common type of STI coinfection, and followed by Hepatitis B (33,9%).Based on anamnesis history, behavioral risk factors (66,1%) was the most frequent risk factor

The Correlation between Personal Hygiene and Intestinal Parasitic Infection in Students of SDN 060889, SDN 060894, and SDN 060831 Medan Yolanda Rebecca Tambunan; Yoan Carolina Panggabean
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 3 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Background. Intestinal parasitic infections are globally endemic diseases. The presence of parasites in the intestine will lead to growth disturbance. Knowledge of personal hygiene is necessary for responding to an illness or other health problems. This study was conducted to determine the correlation between personal hygiene and intestinal parasitic infections in students. Method. This study is an observational analytic study with a cross-sectional design. Samples of this study were taken from students in grades IV, V, VI of SDN 060889, SDN 060894, and SDN 060831 Medan who met the inclusion and exclusion criteria, as many as 62 people. The research data are primarily collected in the form of questionnaires, and fecal specimens examined microscopically using the Kato-Katz and Ether Formol Concentration method. The data that has been collected will be analyzed using bivariate analysis with the chi-square test. Results. From 62 respondents, it was found that 26 (41.93%) respondents suffer from intestinal parasitic infections. There were 16 (25.80%) respondents who had poor personal hygiene, while 46 (74.19%) others had good personal hygiene. A significant correlation was found between personal hygiene and intestinal parasitic infections in study respondents (p = 0.001). Conclusions. There is a significant correlation between personal hygiene and intestinal parasitic infections in this study

Clinical Profile of Diabetic Foot Amputation in Hasan Sadikin Hospital, Bandung, Indonesia Cakra Andhika
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 2 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Diabetes mellitus related to foot ulcers is common. Most studies use amputation rates as a measure of foot management in diabetics. The aim of this study was to determine the description of diabetic foot clinical profile at Hasan Sadikin Hospital, Bandung, Indonesia. The study was conducted on diabetic foot who came to Hasan Sadikin Hospital, Bandung from January 2014 to December 2018, retrospectively. There are 243 diabetic foot patients at Hasan Sadikin Hospital in this study. There are 112 males (46.1%) and 131 females (53.9%). There are more patients with the duration of diabetes was more than 10 years than the shorter duration of diabetes. The 51-60 year age group is the group with the largest percentage (41.6%). Based on the Wagner classification group, patients with grade 2 Wagner diabetic foot became the most group (28.4%). Total amputations were 91 patients (37.5%). The most diabetic foot management is debridement, which is 110 patients (45.3%). The most common type of amputation is below knee amputation, which is 45 patients (49.5%).

The Effect of Fasting Ramadhan on Malondialdehyde Levels Stress Oxidative Paramater in Obese Patient Septi Nina Maria Ginting; Melati Silvanni Nasution
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 2 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Obesity induces the formation of reactive oxygen species (ROS) which is produce oxidative stress that is involved in various pathological processes such as malondialdehyde (MDA) which is a highly toxic molecule. In Indonesia, Muslims are fasting for 13-14 hours during Ramadhan. Researchers interested in conducting research on the effect of fasting Ramadhan on oxidative stress (MDA levels) in individuals with obesity. This research is a prospective cohort. The study was held on March – May 2019 at Outpatient Clinic Endocrinology of RSUP. H. Adam Malik Medan with the approval of the FK USU Research Ethics Commission and according to the criteria of inclusion and exclusion. The Data is analyzed by using the SPPS program where p < 0.05 is considered significant. The results of the study obtained a meaningful decline in the level of MDA before and after the fasting of Ramadhan (p < 0.001). The median rate of MDA before Ramadhan was 4.88 nmol/ml (1.68-101,5 nmol/ml) and after Ramadhan fasting the median rate of MDA became 3.96 nmol/ml (0.97-92,20 nmol/ml). There was decreased of oxidative stress parameter MDA levels after Ramadhan fasting in obese patients.

The Differences of TNF-α Levels and BMI in Diabetic Patients with Pulmonary Tuberculosis After Intensive Phase of Tuberculosis Treatment Wika Lydia; Melati Silvanni Nasution; Dian Anindita lubis; Muhammad Aron Pase
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 2 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Abstract. Introduction. Diabetes Melitus (DM) can cause complications, such as pulmonary tuberculosis (TB). Metabolic disorders are thought to be related to Tumor Necrosis Factor-α (TNF-α) metabolism, adipocytokines secreted by macrophages, which inhibit insulin transduction, has anti-mycobacterial activity, however, also negatively affect pathological TB process. This study aims to determine differences in TNF-α levels and Body Mass Index (BMI) in DM with pulmonary TB after intensive phase of antituberculosis treatment. Method. This prospective comparative analytical study with one-group pretest-posttest design, conducted during August 2019-September 2019 in outpatient of Type 2 DM with pulmonary TB at USU Hospital, Madani Medan Hospital, Teladan Health Center and Laboratory of Haji Adam Malik Medan after approval from the Health Research Ethics Commission. Data were analyzed after normality test, then mean difference and correlation test by using the SPPS program where p <0.05 was considered significant. Results. This study showed an increase BMI, and decrease of fasting blood glucose, 2-hour post-prandial blood glucose, HbA1C and TNFα levels before and after intensive phase of antituberculosis treatment (p = 0,000; p = 0,000; p = 0,000; p = 0,000). Conclusion. There was a significant increase of BMI and decrease of TNFα level after intensive phase of antituberculosis treatment.

Correlation Between Duration Of Protease Inhibitor Therapy With Insulin Resistance In HIV Patients M. Arif Habibi Nasution; Melati Silvanni Nasution; Dian Anindita Lubis
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 2 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Abstract Metabolic diseases related to Human Immunodeficiency Virus (HIV) caused an increase in the workload of health services. Prevalence of HIV infection in Indonesian provinces varied considerably, ranging from less than 0.1% to 4%. Several studies have analyzed the correlation between insulin resistance and the usage of antiretroviral drugs, especially protease inhibitors. The main mechanism that responsible for insulin resistance is related to glucose transporter inhibition (GLUT4). This study objective is to assess the correlation between prolonged administration of protease inhibitors and insulin resistance in patients with that have diagnosed with HIV. Method. This research is an observational research using a cross-sectional design. The study was carried at the POSYANSUS Polyclinic at H. Adam Malik General Hospital in August - December 2019. The study sample were 34 HIV-treated patients receiving protease inhibitor ARV therapy. The study was analysed using chi square. Results. The characteristics of the study subjects had the most frequent age range at the age of 34 - 49 years (54.3%), men (71.4%) and women (28.6%). The longest use of antiretroviral drugs is most in the 6-12 months group (60%). Insulin resistance number in this study was 13 people (37.1%). The average HOMA-IR value of the study subjects was 2 (0.8-16.5), fasting blood sugar levels were 86 (70-283) mg / dl, fasting insulin levels were 9.1 (4.1-79.4) (µU / ml)., urea levels of 20.88 ± 9.7 mg / dl and creatinine levels of 0.81 ± 0.15 mg / dl. There was a significant correlation between the duration of ARV treatment with insulin resistance (p = 0.018; OR 7.65) Conclusion. There is a significant correlation between the duration of ARV treatment with insulin resistance. The longer Protease Inhibitor was used, the bigger insulin resistance.

Effects of Ramadan Fasting on Lipid Profiles and Interleukin-6 in Obese Patients: Effects of Ramadan Fasting on Lipid Profiles and Interleukin-6 in Obese Patients Frihastina Lubis; Muhammad Aron Pase
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 2 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Abstract. Obesity can cause a state of chronic low-grade inflammation due to hypertrophy and hyperplasia of adipose tissue which is not followed by the formation of balanced vascularization. Interleukin-6 is one of the mediators of inflammation that results from obesity. Changes in lifestyle during fasting for the entire month of Ramadan are thought to have an effect on the lipid profile and inflammatory mediators. Method. This research is a prospective cohort observational study conducted in March 2019-May 2019 endocrine polyclinic outpatient clinic Haji Adam Malik Hospital Medan in 30 subjects. Anthropometric measurements and examination of lipid profiles and IL-6 levels, one week before Ramadan fasting and the fourth week of Ramadan. Results. This study showed that there were significant differences in total cholesterol and HDL levels in the study subjects before and after Ramadan fasting (p <0.001; p = 0.049). Also found significant differences in median IL-6 study subjects before and after Ramadan fasting (p <0.001). Conclusion. There was a decrease in levels of IL-6, a decrease in total cholesterol and a statistically significant increase in HDL in obese patients undergoing Ramadan fasting.

Relationship Between Staging and Carcinoembryonic Antigen Serum Levels In Colorectal Cancer Patients' Chandra Agusrly; Taufik Sungkar; Gontar Alamsyah Siregar
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 3 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

The staging can be used as one of the prognostic factors providing a clinical picture of the patient in the future in colorectal cancer patient. In addition, carcinoembryonic antigen (CEA) as tumor markers can determine the commonly used diagnosis and prognosis of colorectal cancer. Objective: The aims study was to investigate the relationship of the staging and carcinoembryonic antigen serum levels in colorectal cancer patients. Methods. This was an analytical study with a cross-sectional design. The sample used was colorectal cancer patients at H. Adam Malik General Hospital, Medan from January 2016 to December 2018. As many as 52 subject study who met the inclusion and exclusion criteria. The Kruskal-Wallis test was used to determine relationship between staging and CEA serum levels. Results: The median value of carcinoembryonic antigen levels in Stage I, II, III, and IV group was (2.74 ng/ml vs 6.16 ng/ml vs 2.52 ng/ml, vs 26.87 ng/ml; p=0.003) respectively. Conclusion: There was relationship between staging and carcinoembryonic antigen serum levels in colorectal cancer patient

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Contact Name Dharma Lindarto

Contact Email jetromi@usu.ac.id

Phone +6282168842564

Journal Mail Official jetromi@usu.ac.id

Editorial Address Jalan Dr T Mansur No 9 Padang Bulan, Kecamatan Medan Baru, Kota Medan, Sumatera Utara, Indonesia

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Contact Name
Dharma Lindarto

Contact Email
jetromi@usu.ac.id

Phone
+6282168842564

Journal Mail Official
jetromi@usu.ac.id

Editorial Address
Jalan Dr T Mansur No 9 Padang Bulan, Kecamatan Medan Baru, Kota Medan, Sumatera Utara, Indonesia

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Unknown,

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INDONESIA