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Hadi Barru Hakam Fajar Siddiq
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Lembaga Penelitian dan Pengabdian Masyarakat Akademi Farmasi Jember. Jl. Pangandaran No. 42 Antirogo, Jember
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Jurnal Ilmiah Farmasi Akademi Farmasi Jember
Published by Akademi Farmasi Jember
ISSN : 25034707     EISSN : 2615756X     DOI : https://doi.org/10.53864/jifakfar
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmiah Farmasi Akademi Farmasi Jember merupakan Jurnal yang menampung artikel ilmiah hasil penelitian di seluruh bidang Farmasi, seperti Farmasi Bahan Alam, Kimia Farmasi, Farmasetika, Farmasi Klinis, Farmasi Komunitas, dan bidang farmasi lainnya.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 6 Documents
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Search results for , issue "Vol 4, No 2 (2021): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER" : 6 Documents clear
THE EFFECT OF VARIATIONS IN THE CONCENTRATION SORBITOL AND CASSAVA LIQUID SUGAR (Manihot esculenta Crantz) OF SWEETENER ON THE PHYSICAL PROPERTIES OF GUMMY CANDIES PARACETAMOL Dewi - Rashati
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Vol 4, No 2 (2021): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (429.034 KB) | DOI: 10.53864/jifakfar.v4i2.74

Abstract

Gummy candies paracetamol is chew candy containing the active subtance paracetamol with sweetener of sorbitol and cassava liquid sugar. The purpose of this study was to determine the effect of variations in the concentration of sorbitol and cassava liquid sugar as sweeteners on the physical properties of gummy candies paracetamol. Formulation of paracetamol gummy candies using diference concentration of sorbitol (20%, 15%, 10%) and cassava liquid sugar (40%, 45%, 50%).was used as the method pre-experimental design research method with one-shot case study design. Testing the physical properties of the preparations that have become chewing gum includes organoleptic tests, weight uniformity tests, pH tests and then the results are compared with the requirements in the literature. The results of the research on the physical properties of paracetamol gummy candy concluded that variations in the concentration of sorbitol sweetener and cassava liquid sugar had an effect on the uniformity of weight. Variations in the concentration of sorbitol sweetener and cassava liquid sugar did not affect the physical organoleptic properties of aroma, color, taste, texture, and physical properties of pH.Keywords : paracetamol, gummy candies, sorbitol, cassava liquid sugar
STABILITAS FISIK EMULGEL MELOKSIKAM MENGGUNAKAN METODE FREEZE THAW ASA FALAHI
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Vol 4, No 2 (2021): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (451.1 KB) | DOI: 10.53864/jifakfar.v4i2.75

Abstract

Emulgel is a semi-solid preparation, in the form of an emulsion where the viscosity is increased by the addition of the gelling agent. Emulgel can be used for formulations of active substances that are difficult to dissolve in water. Meloxicam is a first-line treatment to treat rheumatoid arthritis and osteoarthritis. The aim of the study was determine the stability of the physical properties of emulgel meloxicam with the Freeze thaw test. The research design used was quasi experimental. In this study there were 2 storage temperatures, the freeze temperature of 4-8oC and thaw temperature of 40-48oC. The treatment was carried out in 3 cycles for 6 days. Physical stability test of organoleptic (color, odor, and dosage form) showed no difference during storage. Physical stability test of homogenity also showed no difference during storage. Physical stability of the emulsion type showed that there was no phase separation in the emulsifying gel during storage. Significance of pH is 0,083 (p 0,05), viscosity is 0,083 (p0,05), and spreadabilityis 0,102 (p 0,05) can be interpreted that the physical stability of pH, viscosity and dispersion power has no significant difference. From all research data, it can be seen that the meloxicam emulgel preparation did notchanges in physical stability after passing 3 cycles.
PEMISAHAN PROTEIN DALAM DARAH PENDERITA DIABETES MELLITUS TIPE 2 UNTUK PENGEMBANGAN MOLEKUL BIOMARKER Dewi Riskha Nurmalasari
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Vol 4, No 2 (2021): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (383.784 KB) | DOI: 10.53864/jifakfar.v4i2.76

Abstract

Diabetes mellitus (DM) is a disorder of the chronic metabolic system due to insufficiency of insulin function. DM is classified into two main categories, type 1 and type 2. The purpose of this study was to separate proteins using the SDS-PAGE method to determine the potential protein profile as a biomarker contained in the blood of type 2 DM patients, so that the results of the analysis can be used as an indicator of early detection of type 2 DM. This research is a true experimental research. The samples of this study were the blood of 20 patients with type 2 DM in Sukorejo Bangsalsari Village and the blood of 5 patients who non  DM in Sukorejo Bangsalsari Village. sampling technique was randomized controlled trial, after the blood collection process, blood serum was then prepared at the Molecular Biology Laboratory, FMIPA UNEJ, then protein analysis was performed using the 1D-gel electrophoresis (SDS-PAGE) method. The results of protein characterization using SDS-PAGE analysis with blood serum of type 2 DM patients and serum of healthy people (non-patients) as negative controls, obtained protein bands that are less specific to potential targets, because the results of running are still not good, so it is not possible to know the biomarker protein profile in the blood of patients with type 2 DM in Sukorejo Bangsalsari Village, and the results of this analysis still cannot be used as an indicator for early detection of type 2 diabetes mellitus. Analysis of potential proteins profile as biomarkers using SDS-PAGE analysis has revealed three bands which had molecular weights of 28, 45 and 235 kDa. Keywords: Diabetes mellitus, Biomarker, SDS-PAGE
PENGARUH VARIASI KONSENTRASI GLISERIN TERHADAP SIFAT FISIK OBAT KUMUR EKSTRAK DAUN BELUNTAS (Pluchea indica L.) MIKHANIA CHRISTININGTYAS ERYANI
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Vol 4, No 2 (2021): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (541.07 KB) | DOI: 10.53864/jifakfar.v4i2.57

Abstract

Mouthwash is an aqueous solution used as a cleanser to improve oral health, aesthetics, and breath freshness. The purpose of this study was to determine the effect of variation concentration of glycerin in beluntas leaf extract (Pluchea indica L.) on the physical properties of mouthwash. Extraction was using maceration method with 5000 ml of 96% ethanol as a solvent. Beluntas leaf extract mouthwash was made in 3 formulas with different glycerin concentration which were 10% (F1), 15% (F2) and 20% (F3). Evaluation includes organoleptic, pH and viscosity tests. The organoleptic test of the mouthwash on the three formulations was brown in color, tasted slightly sweet and had a distinctive minty smell. pH of three formulas were 6.16 - 6.20. Data processing using One Way Anova showed that there was no effect of glycerin variations concentration to pH of mouthwash but there was an effect of glycerin variations concentration to the viscosity of mouthwash.
The Prescription Pattern And Rationality Of Antibiotics Usage In General Surgery Polyclinic Patient At RSD Kalisat In October - December 2020 CHURORI RORIK CAHYONO
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Vol 4, No 2 (2021): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (42.736 KB) | DOI: 10.53864/jifakfar.v4i2.64

Abstract

ABSTRACTBackground research: Antibiotics are the most widely used drug class in the world due to the high incidence of bacterial infections. The high use of antibiotics but not balanced with the rational use of antibiotics can have a negative impact, one of which is resistance. Objective: This study was conducted to examine the prescribing pattern and rationale for the use of antibiotics in the Kalisat Jember Hospital. Research method: This study used a descriptive design, data collection was carried out retrospectively which was taken from October to December 2020 at the surgical clinic at the Kalisat Jember area hospital. Result and coclusion: Based on the calculation results, the number of samples used in this study were 263 prescription sheets with antibiotics. From the results of the study, it was found that the most prescribed pattern of antibiotic prescribing was cefixime as many as 165 prescriptions (62.74%) and the most antibiotic preparations prescribed in tablet form were 253 prescriptions (96.20%). From the results of the study, it was also found that the rationality of the use of antibiotics, namely the accuracy of the dose of 100%, the accuracy of the frequency of 99.24% and the accuracy of the duration of 100%.Keywords: Antibiotic, rational, prescription
THE LEVEL OF MOTHER’S KNOWLEDGE ON THE USE OF ZINC IN TODDLERS WITH DIARRHEA IN KARANG PRING HAMLET, RW 01, SUMBER JERUK VILLAGE Dewi - Rashati
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Vol 4, No 2 (2021): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (383.744 KB) | DOI: 10.53864/jifakfar.v4i2.73

Abstract

 Diarrhea is influenced by several factors, including environmental conditions, community behavior, community services, nutrition, population, education which includes knowledge, and socio-economic conditions. Diarrhea is defecation in the form of liquid more than three times in one day and lasts for two or more days. The cause of diarrhea is mostly due to infection.Prevention of diarrhea that can be done is to continue breastfeeding, formula milk, and solid baby food, give ORS or sugar-salt solution to replace lost fluids, give foods that contain fiber, and give zinc for 10 consecutive days.The purpose of this study was to determine the level of mother's knowledge of the use of zinc in toddlers with diarrhea in Karang Pring RW 01, Sumber Jeruk village in the realm of knowing, understanding, and application. The method used is descriptive method with cross sectional analysis research design. In this study, the researcher used a validated questionnaire instrument. The sampling technique used total sampling and obtained 44 samples.Based on the results of data analysis, it was obtained that the percentage level of mother's knowledge on the use of zinc in toddlers with diarrhea in Karang Pring RW 01, Sumber Jeruk village for the July 2021 period in the tofu domain was 64.6%, the understanding domain was 74.2%, and in the application domain 72.7 %. The conclusion in this study is that the realm of knowing is categorized as sufficient, the realm of understanding is categorized as sufficient and in the realm of application it is categorized as sufficient. Keywords: Knowledge level, Diarrhea, zinc

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