cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
LPPM STIFAR
Contact Email
mfi_stifar@yahoo.com
Phone
+6224-6706147
Journal Mail Official
mfi_stifar@yahoo.com
Editorial Address
Sekolah Tinggi Ilmu Farmasi Yayasan Pharmasi Semarang Jl. Sarwo Edhi Wibowo KM 1 Plamongansari, Semarang
Location
Kota semarang,
Jawa tengah
INDONESIA
Media Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Farmasi Yayasan Pharmasi Semarang
ISSN : 19788495     EISSN : 26551462     DOI : https://doi.org/10.53359/mfi.v17i1
Core Subject : Health, Science, Education,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Other
Media Farmasi Indonesia publishes original article in the all scopes of Pharmaceutical Science such as Pharmaceutics, Biopharmaceutics, Drug Delivery System, Chemical Pharmacy, Pharmaceutical Technology, Pharmaceutical Microbiology and Biotechnology, Pharmacology and Toxicology, Pharmacokinetics, Pharmaceutical Chemistry, Pharmaceutical Biology, Community and Clinical Pharmacy, Management Pharmacy, Alternative Medicines.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "Vol. 15 No. 1 (2020): Media Farmasi Indonesia" : 5 Documents clear
UJI DAYA ANTIBAKTERI SEDIAAN PASTA GIGI EKSTRAK DAUN BINAHONG (Anredera cordifolia (Tenore) Steen) TERHADAP PERTUMBUHAN BAKTERI Streptococcus mutans Erli Puji Nurhartanti; Ahmad Fuad Masduqi
Media Farmasi Indonesia Vol. 15 No. 1 (2020): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (434.322 KB) | DOI: 10.53359/mfi.v15i1.137

Abstract

Ekstrak daun binahong (Anredera cordifolia (Tenore) Steen) telah terbukti memiliki aktivitas antibakteri Streptococcus mutans, bakteri penyebab karies gigi. Formulasi menjadi sediaan pasta gigi memudahkan penggunaan ekstrak daun binahong dalam mengatasi karies gigi. Penelitian ini bertujuan untuk mengetahui adanya daya antibakteri ekstrak daun binahong pada sediaan pasta gigi terhadap pertumbuhan bakteri Streptococcus mutans. Ekstrak daun binahong (Anredera cordifolia (Tenore) Steen) diperoleh dengan remaserasi menggunakan pelarut etanol 70% selama 3 hari. Uji karakteristik fisik sediaan pasta gigi meliputi: organoleptis, homogenitas, pH, daya sebar, daya lekat, dan viskositas. Uji daya antibakteri dilakukan dengan menggunakan metode sumuran teknik pour plate. Pengukuran daya antibakteri sampel ditentukan dengan mengukur zona bening yang terbentuk disekitar sumuran. Hasil penelitian menunjukkan bahwa ekstrak daun binahong mengandung senyawa alkaloid, flavanoid, tanin dan triterpenoid. Hasil uji karakteristik sediaan pada uji homogenitas ketiga formula sama. Berdasarkan uji statistika menunjukkan adanya perbedaan yang tidak signifikan pada uji pH, viskositas, daya lekat, daya sebar (nilai Sig. >0,05). Hasil uji daya antibakteri diperoleh rerata zona bening untuk konsentrasi 10%, 15%, dan 20% adalah 0,466cm; 0,574cm dan 0,628cm dengan hasil rerata kontrol positif adalah 0,465 cm. Penelitian ini dapat disimpulkan bahwa sediaan pasta gigi ekstrak daun binahong (Anrendera cordifolia (Tenore) Steen) memiliki daya antibakteri terhadap pertumbuhan bakteri Streptococcus mutans. Terdapat perbedaan daya antibakteri sediaan pasta gigi ekstrak daun binahong konsentrasi 10%, 15% dan 20% terhadap pertumbuhan bakteri Streptococcus mutans. Sediaan pasta gigi ekstrak daun binahong konsentrasi 10% memiliki daya antibakteri paling efektif terhadap pertumbuhan bakteri Streptococcus mutans.
EVALUATION OF THE USE OF ANTI-NON STEROID INFLAMATION DRUGS ON GERIATRI Sikni Retno Karminingtyas; Dian Oktianti; Nova Hasani Furdiyanti; Mira Sandriana; Arinda Maya Kusuma
Media Farmasi Indonesia Vol. 15 No. 1 (2020): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (643.685 KB) | DOI: 10.53359/mfi.v15i1.138

Abstract

Background: Geriatric patients differ from the general patient population. Geriatric differences with other populations include aspects of pharmacokinetics, pharmacodynamics, comorbidities, and the likelihood of adverse drug reactions (ADR). Objective: To determine the accuracy of the dosage and side effects of non-steroidal anti-inflammatory drugs (NSAIDs) in geriatric patients in the Inpatient Installation of Dr.Asmir Salatiga. Methods: The study was conducted non-experimental (observational), using descriptive methods and prospective data collection. Samples were 25 patients with total sampling method. Data analysis included drug use, dose accuracy and evaluation of drug side effects using the Naranjo algorithm. Results: Geriatric patients using the most non-steroidal anti-inflammatory drugs were 18 patients (72%). The largest group of non-steroidal anti-inflammatory drugs is the oxikam group of 12 patients (48%). The exact dosage of non-steroidal anti-inflammatory drugs is 19 cases (76%) on the right dose. Evaluation of drug side effects based on the Naranjo algorithm obtained scores for the "probable / probable category of 6 patients (24%) and the feasible category of 19 patients (76%). Conclusion: The correct dosage of non-steroidal anti-inflammatory drugs is 19 cases (76%) right dose. The evaluation of the side effects of non-steroidal anti-inflammatory drugs was the "probable" category of 6 patients (24%) and the feasible category of 19 patients (76%).
PERBAIKAN GAMBARAN LESI ATEROSKLEROTIK DENGAN PEMBERIAN EKSTRAK BETA VULGARIS PADA TIKUS MODEL DIET ATHEROGENIK Fransisca Pramesshinta Hardimarta; Kartika Ikawati; Christina Ary Yuniarti
Media Farmasi Indonesia Vol. 15 No. 1 (2020): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.432 KB) | DOI: 10.53359/mfi.v15i1.140

Abstract

Atherosclerosis is characterized by the accumulation of fat in the arteries so it forms plaque that causes thickening of the intima and blockage of the arteries. Beet roots are rich of phytochemical compounds that have antioxidant activity. Design of research is a laboratory experimental study with a Post Test Only Randomized Control Group Design. The population of this study was male Wistar rats with age 2-3 months and body weight 125-200 grams. The study sample was randomly selected and consists of 7 groups and 5 rats for each group. The average number of foam cells in the baseline group is 17.6; negative control group is 65.8; positive control is 54.6; group I is 38.8; group II is 27.4; group III is 46.4; and group IV is 42.4. The average thickness of the aortic intima tunica in the baseline group is 136.8 µ; negative control group is 251.4 µ; positive control is 211.8 µ; group I is 202.8 µ; group II is 184 µ; group III is 242.8 µ; and group IV is 210.6 µ. Statistical test results showed that there were significant differences in supplementation of beet root extracts against aortic thickness and the number of foam cells in rats fed atherogenic diets.
HUBUNGAN DUKUNGAN SOSIAL DENGAN DEPRESI PADA PASIEN PASCA STROKE (Studi Analitik Observasional di Rumah Sakit Islam Sultan Agung Semarang) Ika Rosdiana
Media Farmasi Indonesia Vol. 15 No. 1 (2020): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (335.181 KB) | DOI: 10.53359/mfi.v15i1.141

Abstract

Stroke is one of diseases which can be the number one cause of disability in the worldx and cause of death number two in the world. The incidence of stroke increases with increasing age. The purpose of this study was to determine the relationship of social support with depression in stroke patients. This type of research uses analytic observation with cross sectional design. The sample used was non-hemorrhagic post-stroke patients and post-stroke hemorrhagic outpatients in the medical rehabilitation clinic of Sultan Agung Islamic Hospital Semarang by taking into account the inclusion and exclusion criteria. Data collection by visiting the patient's house and conducting interviews using social support questionnaires and BDI. Data analysis using Pearson test. The results obtained were 84 non-hemorrhagic stroke patients and 30 hemorrhagic stroke patients. Most age is experienced at the age of 61-70 years as much as 45.2% in non-hemorrhagic strokes and 43% in hemorrhagic strokes. The most sex is female 53.6% in non-hemorrhagic stroke and 60% in men in hemorrhagic stroke. In non-hemorrhagic stroke patients, it was found that 92.9% received high social support while in hemorrhagic stroke patients, high social support was 73,3%. The degree of depression obtained a minimum of 85.7% depression according to the BDI scale for non-hemorrhagic stroke patients and the severe BDI scale of 43.3% for hemorrhagic stroke patients. There was no significant relationship between social support and the degree of depression in non-hemorrhagic stroke patients hemorrhagic stroke patient The conclusion was not found a meaningful relationship between social support and depression level in non-hemorrhagic and hemorrhagic post-stroke patients
DETERMINASI TOTAL FLAVONOID, TOTAL FENOLIK, DAN AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN INSULIN (Smallanthus Sonchifolius) DENGAN METODE PERKOLASI Dewi Ramonah; Muhammad Ryan Radix Rahardhian; Chintiana Nindya Putri
Media Farmasi Indonesia Vol. 15 No. 1 (2020): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (656.674 KB) | DOI: 10.53359/mfi.v15i1.143

Abstract

Indonesia kaya akan keanekaragaman hayati yang berkhasiat sebagai pengobatan. Salah satunya adalah daun insulin yang mengandung senyawa fenolik golongan flavonoid, dimana senyawa tersebut memiliki potensi sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui kandungan senyawa ekstrak etanol daun insulin (EDI) dengan metode perkolasi pada skrining fitokimia, kromatografi lapis tipis (KLT), determinasi total phenolic content (TPC), total flavonoid content (TFC), dan aktivitas antibakteri terhadap bakteri Sthapylococcus aureus. Hasil skrining fitokimia dan TLC membuktikan bahwa, EDI mengandung senyawa flavonoid, tanin, alkaloid, saponin dan steroid. Nilai TPC 6,7315±0,15 mg/g Gallat Acid Equivalent (GAE), Nilai TFC 66,1857±13,34 mg/g Quercetin Equivalent (QE), Aktivitas antibakteri terhadap bakteri Sthapylococcus aureus pada konsentrasi 5, 10 dan 15 % berturut-turut adalah 1,632±0,00; 1,957±0,00; dan 2,528±0,02 . Berdasarkan hasil tersebut membuktikan bahwa EDI memiliki potensi sebagai sumber fenolik golongan flavonoid dan memiliki aktivitas antibakteri terhadap bakteri Sthapylococcus aureus, potensi terbesar pada EDI konsentrasi 15 %. Penelitian selanjutnya perlu dilakukan pemurnian dan karakterisasi senyawa bioaktif untuk aplikasi industri makanan, nutraceutical dan farmasi.

Page 1 of 1 | Total Record : 5

 1 

Filter by Year

2020 2020


Reset
Filter By Issues
All Issue Vol. 18 No. 2 (2023): Media Farmasi Indonesia Vol. 18 No. 1 (2023): Media Farmasi Indonesia Vol. 17 No. 2 (2022): Media Farmasi Indonesia Vol. 17 No. 1 (2022): Media Farmasi Indonesia Vol. 16 No. 2 (2021): Media Farmasi Indonesia Vol. 16 No. 1 (2021): Media Farmasi Indonesia Vol. 15 No. 2 (2020): Media Farmasi Indonesia Vol. 15 No. 1 (2020): Media Farmasi Indonesia Vol. 14 No. 2 (2019): Media Farmasi Indonesia Vol. 14 No. 1 (2019): Media Farmasi Indonesia Vol. 13 No. 2 (2018): Media Farmasi Indonesia Vol. 13 No. 1 (2018): Media Farmasi Indonesia Vol. 12 No. 2 (2017): Media Farmasi Indonesia Vol. 12 No. 1 (2017): Media Farmasi Indonesia Vol. 11 No. 2 (2016): Media Farmasi Indonesia Vol. 11 No. 1 (2016): Media Farmasi Indonesia Vol. 10 No. 1 (2015): Media Farmasi Indonesia Vol. 9 No. 2 (2014): Media Farmasi Indonesia Vol. 9 No. 1 (2014): Media Farmasi Indonesia Vol. 8 No. 2 (2013): Media Farmasi Indonesia Vol. 8 No. 1 (2013): Media Farmasi Indonesia Vol. 7 No. 2 (2012): Media Farmasi Indonesia Vol. 6 No. 2 (2011): Media Farmasi Indonesia Vol. 6 No. 1 (2011): Media Farmasi Indonesia Vol. 5 No. 1 (2010): Media Farmasi Indonesia Vol. 4 No. 1 (2009): Media Farmasi Indonesia More Issue