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Makara Journal of Health Research
Published by Universitas Indonesia
ISSN : 23563664     EISSN : 23563656     DOI : https://doi.org/10.7454/msk
Core Subject :
Makara Journal of Health Research (MJHR) is a peer-reviewed and scientific journal published by Universitas Indonesia. Starting from 2019 onwards, MJHR is redirecting its scope, focusing on publishing research articles relevant to non-communicable diseases (NCDs) addressing issues of surveillance, disease management and health policy in the Asia Pacific and Mediterranean countries. Relevant academic articles regarding NCDs analyzed from an integrated perspective including individual and population level, experimental and clinical approaches, epidemiology, public health, disease prevention and health promotion, diagnosis, treatment, prognosis and palliative care are welcome.
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Articles 200 Documents
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The Pharyngeal Airways of Patients with Class II Malocclusion: A Cone-Beam Computed Tomography Analysis Ay Ünüvar, Yazgı; Bilgiç Zortuk, Fundagül; Özer, Törün; Beycan, Kadir
Makara Journal of Health Research Vol. 25, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: This study aimed to compare the minimum axial (min Ax) area and the volumes of the nasopharyngeal (NP) and oropharyngeal (OP) airways of patients with Class II malocclusion with different sagittal positions of the mandible and maxilla and patients with Class I malocclusion with normal jaw positions. Methods: Airway areas and volumes of 51 patients with Class I malocclusion with normal maxillary and mandibular positions (0 < ANB < 4, 84 > SNA > 80, and 82 > SNB > 78) were compared with 21 patients with Class II malocclusion with normal maxillary and retrognathic mandibular positions (ANB>4, 84>SNA>80, and SNB4, SNA>84, and 82>SNB>78). Results: In the comparison of airway measurements between Class I and Class II groups, significant differences were found in the OP airway volume, total airway volume, and minimum OP axial area. Patients with Class II mandibular retrusion had smaller OP airway volume. The total airway volume and min Ax area were significantly lower in the Class II mandibular retrusion group than in other groups. Conclusions: The sagittal position of the jaws affects the OP airway volume and the minimum axial airway area, but not the NP airway volume.
Use of Internet Platforms for Information About Sensitive Teeth Among Indonesian Adults: A Cross-Sectional Study Khairina, Safira; Maharani, Diah Ayu; Yavuz, Yasemin; Setiawati, Febriana
Makara Journal of Health Research Vol. 25, No. 2
Publisher : UI Scholars Hub

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Background: The behavior of seeking oral health information (OHI), especially the topic of sensitive teeth (ST), among the Indonesian adult population has rarely been studied. Hence, the current work aimed to analyze the characteristics of the Indonesian adult population who reported having ST and to explore their practice of self-medication in terms of their behavior of seeking OHI on the internet. Methods: A cross-sectional study was conducted between January and March 2021 in Indonesia. This study used a self-administered questionnaire comprising questions about sociodemographic data, oral health behavior, diet, and subjective oral health. Bivariate analysis based on a chi-square test was conducted for statistical evaluation. Results: Results showed that 63.3% of the respondents used Google, 24.5% used Instagram, and 24.2% used YouTube to search for OHI about ST. Most of them felt improvement with self-perceived medication, with YouTube (odds ratio [OR] = 5.13, 95% confidence interval [CI] = 2.26, 11.62), Google (OR = 2.94, 95% CI = 1.79–4.84), and Instagram (OR = 1.84, 95% CI = 1.11, 3.06) as their main OHI sources. Conclusions: Internet platforms provide information that helps adults to cope with their ST. Professionals should consider using internet-based interventions as a powerful tool for dental health education.
Loneliness and Health Outcomes Among Malaysian Older Adults Hussein, Siti Zuhaida; Ismail, Azera Hasra; Abu Bakar, Suraya Hanim
Makara Journal of Health Research Vol. 25, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Loneliness is a major social problem among the elderly all over the world. Methods: A community-based survey was conducted among 380 community-dwelling older adults residing in Malaysia. A proportional stratified random sampling method was used to examine the relationship between health factors and loneliness. Data were collected using the short-form Social and Emotional Loneliness Scale for Adults, Geriatric Depression Scale-15, and RAND SF-20. p < 0.05 was considered to be statistically significant, and data analysis was performed using Statistical Package for the Social Sciences Statistics 26.0 for Windows. Results: Results revealed that 32.6% of the respondents had social loneliness, 39.9% had emotional loneliness, and 9.2% had family loneliness. Bivariate analyses showed that social and emotional loneliness are significantly related to depression. Moreover, emotional and social loneliness were significantly associated with chronic illness. The results of the multiple logistic regression indicated that depression was a significant predictor of social loneliness (OR = 2.5, 95% CI: 1.1–5.7; p = 0.03) and that chronic illness (OR = 0.4, 95% CI: 0.2–0.8; p = 0.02) remained a significant predictor of family loneliness. Conclusions: The loneliness prevalence experienced by older adults is at a low level. The classification of loneliness in this study would be beneficial in the establishment of loneliness intervention strategies.
Prevalence and Correlates of Frequent and Infrequent Bullying Victimization Among School Adolescents from Five Southeast Asian Countries Peltzer, Karl; Pengpid, Supa
Makara Journal of Health Research Vol. 25, No. 2
Publisher : UI Scholars Hub

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Background: Little is known about the frequency of bullying victimization (BV) among adolescents in Association of Southeast Asian Nations (ASEAN) member states. This study aims to assess the prevalence and correlates of frequent and infrequent BV among school-going adolescents in five ASEAN member states. Methods: The cross-sectional sample of the Global School-based Student Health Survey (GSHS) of 2015 comprised 33,184 school adolescents (14.6 years mean age) from five ASEAN countries. Students completed a paper-based, self-administered questionnaire on BV in their own languages during classroom periods. Multinomial logistic regression was used to predict frequent and infrequent BV, with no BV as the reference category. Results: Results indicate that 30.6% of participants reported any past-month BV, 33.9% in boys and 27.5 in girls, ranging from 11.8% in Laos to 48.7% in the Philippines. In the adjusted multinomial logistic regression analysis of students from the Philippines and Thailand, experience of hunger, sedentary behavior, attendance at physical education classes, being underweight, overweight, or obese, ever amphetamine use, physical assault, school truancy, participation in a physical fight, injury, low peer support, and psychological distress were all associated with BV. Conclusions: Approximately one in three adolescents was bullied. Several associated variables were identified which can assist in targeting strategies of intervention.
Alveolar Bone Loss Analysis on Dental Digital Radiography Image Fitriananda, Aulia Karina; Kiswanjaya, Bramma; Bachtiar-Iskandar, Hanna H
Makara Journal of Health Research Vol. 25, No. 2
Publisher : UI Scholars Hub

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Background: Periodontal disease is the second most common tooth and mouth disease in Indonesia. Moreover, radiographic examination is the most useful tool to evaluate alveolar bone loss and diagnose periodontal diseases. This study aimed to analyze radiographically the relationship between alveolar bone loss and age among patients with chronic periodontitis. Methods: A total of 192 digital periapical images of patients aged 25–40 years were collected. Four regions were selected, including the maxillary and mandibular central incisors and maxillary and mandibular first molars. Alveolar bone loss was measured in the mesial and distal surfaces. Results: The mean and standard deviation for alveolar bone loss in age categories 1 (age 25–32 years) and 2 (age 33–40 years) were 4.03 ± 1.46 and 5.23 ± 2.5 (mm), respectively. Alveolar bone loss demonstrated a significant relationship with patient’s age (p < 0.001, Mann–Whitney U test). Conclusions: The mean and standard deviation of alveolar bone loss reduction in patients with chronic periodontitis was 4.87 ± 0.2 (mm). The alveolar bone loss on the mandibular central incisors’ mesial surface is the highest among other regions.
Patient Care Delivery: Electronic Nursing Documentation in Malaysia Hussein, Siti Zuhaida; Khalip, Norazilah; Hashim, Rosnita; Harun, Rohaizah; Fazilah, Nor Fazlina; Mat Shah, Norazilah
Makara Journal of Health Research Vol. 25, No. 2
Publisher : UI Scholars Hub

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Background: The evolution of nursing documentation from paper to electronic format aims to improve patient safety and care quality. This study aimed to determine the knowledge and attitudes of registered nurses toward electronic nursing process documentation. Methods: This cross-sectional study was conducted among 189 registered nurses who work in medical wards at a teaching hospital in Kuala Lumpur. Simple random sampling was used. Respondents’ knowledge of electronic nursing documentation was measured using a questionnaire developed by Guedes, and their attitudes toward electronic nursing documentation were measured using a questionnaire developed by Hagos. Data analysis was performed using Statistical Package for the Social Sciences Statistics 26.0 for Windows and p < 0.05 was considered significant. Results: In this study, 50.8% of the respondents have a low knowledge level of electronic nursing documentation, and 89.4% have a positive attitude toward electronic nursing documentation. No significant relationship was found between sociodemographic factors, such as age, education level, working experience, knowledge level, and attitude, and electronic nursing documentation. Conclusions: Nurses had a higher knowledge level of and positive attitudes toward electronic nursing documentation. A longitudinal and comparative study was suggested for further research.
Comparative Analysis of Proteomics Biomarkers Associated with Residual Ridge Resorption Induced by Denture Wear Ahmad, Rohana; Mohamad Napi, Ainin Sofia; Lim, Tong Wah; Tan, Su Keng; Karsani, Saiful Anuar; Mazlan, Musalmah; Teh, Lay Kek; Morgano, Steven M; Baba, Nadim Z
Makara Journal of Health Research Vol. 25, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: The biochemical bone turnover markers for residual ridge resorption (RRR) are unclear. Therefore, the present study aimed to determine the biochemical bone turnover markers associated with RRR by comparing proteomics between the compressed mucosa of denture wearers and the non-compressed mucosa of non-denture wearers. Methods: The mucosal specimens of 11 complete-denture wearers were obtained from the alveolar ridge during surgical implant exposure for implant-retained overdentures. All denture wearers had been edentulous and worn dentures for at least 5 years. The tissues of 11 non-denture wearers were taken from the ridge during minor preprosthetic surgery. The mucosal proteins were extracted, purified, precipitated, and subsequently separated by two-dimensional gel electrophoresis for comparative proteomics. Differentially expressed proteins between the groups were analyzed by ANOVA using Progenesis SameSpots software. Results: Comparative proteomics analysis showed significant upregulation of 78 kDa glucose-regulated protein (GRP78; +2.2 fold, p = 0.015) and lumican (+1.8 fold, p = 0.005), as well as significant downregulation of heat shock protein 27 (HSP27; −1.9 fold, p = 0.029) in the denture group. Conclusions: Differential expression of the biochemical bone turnover markers of GRP78, lumican, and HSP27 may occur as a result of denture pressure on the mucosa. These markers may play important roles in RRR.
Preventive Behaviors, Barriers, and Drivers of the COVID-19 Pandemic in Malaysia: A Cross-sectional Survey Ab Malik, Normaliza; Mohd, Rusyda Helma; Abdul Kadir, Nor Ba'yah
Makara Journal of Health Research
Publisher : UI Scholars Hub

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Background: Coronavirus disease 2019 (COVID-19) is a public health concern worldwide. This study aimed to assess the preventive behaviors, barriers, and drivers, including the knowledge and self-efficacy of COVID-19 in Malaysia. Methods: A cross-sectional study was conducted during the COVID-19 outbreak by using a self-administered questionnaire. The instrument used was adopted from the World Health Organization resources. Descriptive statistics were used to describe the categorical data. Chi-square and independent t-test were performed to evaluate the associations between the variables and preventive behaviors. Results: A total of 465 (97.3%) respondents were recorded. The mean age was 34.3 ± 11.8 years old. A high percentage of the respondents (99.4%) were aware of the COVID-19 outbreak, and their knowledge mean score was 18.74 (Standard Deviation [SD]: 2.51). The mean scores of self-efficacy, barriers, and drivers were 11.07 (SD: 1.72), 5.20 (SD: 2.81), and 39.71 (SD: 5.17), respectively. Barriers (Odds Ratio [OR]: 1.10; 95% Confidence Interval [CI]: 1.01, 1.21; p < 0.05) and drivers (OR: 1.12; 95% CI: 1.07, 1.17; p < 0.001) were found to be predictors for social distancing practices. Conclusions: Knowledge and self-efficacy were found to be at good levels, whereas self-efficacy, barriers, and drivers were revealed to be the predictive factors in determining the preventive behaviors. Adherence to preventive measures was largely affected by the behavioral drivers.
Influence of child feeding practices and selected basic conditioning factors on stunting in children between 6 and 24 months of age in Myanmar Phu, Khine-Wai-Wai; Wittayasooporn, Jariya; Kongsaktrakul, Chuanruedee
Makara Journal of Health Research
Publisher : UI Scholars Hub

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Background: A cross-sectional predictive study was carried out to examine the influence of child feeding practices on stunting status of children between 6–24 months in Yangon Children Hospital, Myanmar. This study aimed to assess if dependent-care can influence stunting. Methods: Data were collected by anthropometric measurement from a total of 216 children between 6 and 24 months of age. For mothers, structured interview, demographic form, and infant child feeding index were used. Descriptive statistics, chi-square, and logistic regression were carried out. Results: One-fourth of participants exhibited a low score of infant child-feeding practices, whereas median and high score practice accounted for 39.82% and 34.72%, respectively. Only child feeding practice was shown significant association and predicted stunted children. Low score (0–5) was more likely to be stunted 15.45 times [OR 15.45, 95% CI; 5.58, 42.81] at p = 0.00 and a medium score (6–7) on the infant child feeding index was 4.55 times higher than a high score (8–9) on the infant child feeding index [OR 4.55, 95% CI; 1.72, 12.04] at p = 0.02. Conclusion: Child feeding practice is the only predictor of stunting status of children and intervention program for child feeding practices should be provided.
Protection against neutrophil extracellular trap (NET) toxicity by antioxidant monoHER Astuti, Puji; Beurskens, Danielle M A; Vajen, Tanja; Nicolaes, Gerry A F; Zhang, Ming; Haenen, Guido R M M
Makara Journal of Health Research Vol. 23, No. 2
Publisher : UI Scholars Hub

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Background: Neutrophil extracellular traps (NET) are extracellular fibers produced by activated neutrophils to kill bacteria. NET was recently found to be associated with several diseases, such as autoimmune diseases. NET formation, called NETosis, is reactive oxygen species (ROS) dependent, thereby, prompting us to study its inhibition by potent antioxidant monoHER as well as to study monoHER protection against NET toxicity caused by NET constituent histone 3 on endothelial cells. Methods: Freshly isolated neutrophils from male donors were stimulated with PMA to induce NET formation. The effect of monoHER (50 µM) on oxidative burst (O2●− production) and NET formation was determined by fluorescence microscopy. Flow cytometry was used to determine the protective effect of monoHER against NET toxicity constituent histone 3 in EA.hy926 cells. Data was evaluated using ANOVA followed by the Bonferroni post-hoc test. Results: MonoHER significantly reduced (p < 0.01) O2●− production of PMA-stimulated neutrophils and consequently inhibited NET formation. MonoHER could also counteract histone 3 toxicity in EA.hy926 cells. Conclusions: MonoHER might inhibit ROS-dependent NETosis pathway and also protect the endothelial cells against NET toxicity.

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