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Muammar Fawwaz
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muammar.fawwaz@umi.ac.id
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+6282125556303
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pharmaceutical.reports@umi.ac.id
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Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy Universitas Muslim Indonesia, Jl. Urip Sumohardjo KM 5 Kampus II, Makassar 90231, Indonesia
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Kota makassar,
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INDONESIA
Pharmaceutical Reports
Published by Universitas Muslim Indonesia
ISSN : 28286030     EISSN : 28288734     DOI : https://doi.org/10.33096/pharm%20rep.v1i2
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
Pharmaceutical Reports is a peer-reviewed journal published by the Pharmaceutical Chemistry Laboratory of the Faculty of Pharmacy, Universitas Muslim Indonesia, which was first published in 2022. We published two times a year in January-June and July-December. Our mission is to advance the science and practice of pharmaceutical research by working to develop and maintain competence, ethics, and integrity, and the highest professional standards in the specialty for the benefit of the public. Pharmaceutical Reports publishes studies that contribute to an understanding of some specific areas in pharmaceutical sciences including the following: - Analytical chemistry of organic and natural product compounds using instrumental analysis in pharmaceutical sciences including spectroscopy and chromatography method. - Design, synthesis, and biological evaluation of biologically active compounds, diagnostic agents, or labeled ligands employed as pharmacological tools. - Molecular modifications of reported series that lead to a significantly improved understanding of their structure-activity relationships (SAR). - Structural biological studies (X-ray, NMR, etc.) of relevant ligands and targets with the aim of investigating molecular recognition processes in the action of biologically active compounds. - Pharmaceutics & Biopharmaceutics - Novel & Targeted Drug Delivery - Pharmacology & Toxicology - Pharmaceutical Biotechnology & Microbiology - Pharmacy Practice & Hospital Pharmacy - Drug Regulatory Affairs
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 5 Documents
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Search results for , issue "Vol 1, No 2 (2022): (October) Pharmaceutical Reports" : 5 Documents clear
Total Flavonoid Content of the Bark Extract of Salacca edulis Reinw Nisradhiyah Caesarika Ardin; Mamat Pratama; Harti Widiastuti; Muammar Fawwaz
Pharmaceutical Reports Vol 1, No 2 (2022): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (187.372 KB) | DOI: 10.33096/pharm rep.v1i2.168

Abstract

Salak fruit (Salacca edulis Reinw) is one of the fruits whose bark is not used but contains chemical components in the form of secondary metabolites that are beneficial to health. A previous study reported that the bark of salak fruit has potential as an anti-diabetic, antioxidant. The bark of Salak fruit is traditionally beneficial for the treatment of diabetes mellitus by drying then boiling and drinking the boiled water. Therefore, this study aims to determine the total flavonoid content of the bark extract of the pondoh and honey varieties of salak fruit. A sample of 30 g was dissolved with ethanol in a 10 mL volumetric flask, then 1 mL was pipette and added with 0.2 ml AlCl3 and 0.2 mL potassium acetate then allowed to stand for 30 min at 25°C. After being allowed to stand, it was measured on a UV-Vis spectrophotometer with a wavelength of 442 nm. In the measurement with UV-Vis spectrophotometer, the total flavonoid content of the salak bark extract of pondoh and honey varieties were 5.18 mg QE/g and 5.77, respectively.
Sulfonamide Residue in the Broiler Chicken Circulating in Makassar Muammar Fawwaz; Rais Razak; Masdiana Tahir; Andi Permatasari; Andi Tenri Amula; Seniwati Seniwati
Pharmaceutical Reports Vol 1, No 2 (2022): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (443.376 KB) | DOI: 10.33096/pharm rep.v1i2.169

Abstract

The use of sulfonamide related to drug residual in the product of broiler chicken, like meat and egg. This research aimed to determine the sulfonamides (sulfamerazine, sulfanilamide, and sulfadiazine) on the broiler chicken meat, breast, and egg from the three different slaughterhouses circulating in the City of Makassar. The sample was extracted by acetonitrile and acetone then concentrated. The extract and sulfonamides then analyzed by HPLC method using C18 reverse phased column, UV-Visible detector in the wavelength of 270 nm. The result of study shows that the chromatogram of sample breast and egg has similar retention time with sulfonamides as a standard reference. The breast sample contains sulfamerazine residues, sample B and C contains 0.014 and 0.005 % (w/w), respectively. The egg sample A and D contains sulfadiazine 0.045 and 0.108 % (w/w), respectively. Sample B contains sulfanilamide 0.053 % (w/w). Sample A and B is egg yolk, while sample D is egg whites. Based on the results obtained, this is not suitable for the rules set by JECFA of 0.1 mg/kg (10-5 % w/w) as well as the standard of SNI. It can be concluded that generally broiler chicken breast and egg circulating in the City of Makassar was contaminated by sulfonamide with high concentration.
UV-Visible Spectrophotometric Determination of Formalin Contamination in Tofu Circulated in Maros City - Indonesia Seniwati Seniwati; Haqi Romadhona Qawiy; Aminah Aminah; Tadjuddin Naid
Pharmaceutical Reports Vol 1, No 2 (2022): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (185.538 KB) | DOI: 10.33096/pharm rep.v1i2.170

Abstract

Tofu is one of the healthiest foods because of its high protein content and the quality is equivalent to the quality of animal protein. Formaldehyde has a function as an antibacterial agent that can slow down the activity of bacteria in foods that contain a lot of protein, so formaldehyde reacts with proteins in food and makes food durable, but when it enters the human body, formaldehyde itself is mutagenic and carcinogenic which can trigger the growth of cancer cells. and gene defects in the body. Thus, in this study, we aim to determine the formalin contamination in tofu circulated in Maros City – Indonesia. This research was conducted from December 2014 to June 2015. The analysis of formalin contamination in tofu was conducted in qualitative and quantitative analysis. The qualitative analysis was performed using the specific reagent, and the quantitative analysis was measured by UV-Vis spectrophotometric method. The result showed that sample codes RMD1 and RMD2 with formalin contaminants because the color of the solution produced after the test was red correspond to the positive result. As for the tofu sample with sample code RMD3, the results were negative because it gave a yellow color after adding potassium permanganate reagent. In the quantitative analysis, samples were measured using a UV-Vis spectrophotometer at a wavelength of 571.5 nm. From the measurement process, the result exhibited that the samples RMD1 and RMD2 contain formalin of 5.92 and 3.34 g/gram, respectively.
Criminal Responsibility of the Pharmacist in the Pharmaceutical Services in Indonesia Saparuddin Latu; Aswanto K; Marthen Arie; Alimuddin Alimuddin
Pharmaceutical Reports Vol 1, No 2 (2022): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (205.047 KB) | DOI: 10.33096/pharm rep.v1i2.171

Abstract

Medical malpractice has a long history in Indonesia, with fatal consequences for patients due to negligence from the health practitioner. This study aims to ensure legal certainty in pharmaceutical practice according to laws and regulations. Also, to provide criminal law sanctions for pharmacists in pharmaceutical practices that lead to criminal acts. The method used was qualitative empirical normative research with a literature study. This research was conducted qualitatively based on data triangulation which resulted from three ways: interview, participant to observation, and review of organizational records (document records). Data collection usually uses qualitative research observation, documentation, and interview methods. This study discusses legal provisions related to health and pharmaceutical services and interviews with ten people at Dr. Wahidin Sudirohusodo Regional General Hospital, Makassar, and five people from Wamena Regional General Hospital, Jayawijaya Regency, Papua. Our study exhibited that implementing a pharmacist's practice was based on the prevailing laws and regulations. The pharmaceutical practice in question starts from planning, procurement, storage, distribution, evaluation, and provision of drug information and monitoring of drug side effects. These practices are based on Government Regulation No. 51 of 2009 article 4. This regulation is stated to protect patients and the public in obtaining and stipulating pharmaceutical preparations and pharmaceutical services. In addition, to maintain and improve the quality of implementation of pharmaceutical work by using developments in science and technology as well as laws and regulations; and provide legal certainty for patients, communities, and pharmaceutical workers. In the criminal responsibility of pharmacists in pharmaceutical services that have resulted in illegal acts, there have not been cases that have reached court proceedings. Nevertheless, there are cases where actions that have resulted in criminal acts have occurred in the field. Still, mediation can resolve them to reach a consensus with unique mediation.
Determination of Total Phenolic Levels of Ethyl Acetate Fraction of Clove Leaves (Syzygium aromaticum (L) Merr) Arniati Arniati; Mamat Pratama; Muzakkir Baits; Masdiana Tahir
Pharmaceutical Reports Vol 1, No 2 (2022): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.887 KB) | DOI: 10.33096/pharm rep.v1i2.167

Abstract

Clove is a spice plant used in the kretek cigarette industry, food, beverage, and medicine. Clove leaves contain chemical compounds, namely saponins, flavonoids, tannins, and essential oils. The exploration of clove leaves has not been maximally carried out. Therefore, this study aims to determine the total phenolic content in the ethyl acetate fraction of clove leaves by using gallic acid as a comparison. Clove leaves were powdered and then macerated by ethanol. The ethanol extract was dissolved in distilled water and it was fractionated with ethyl acetate on a separating funnel. The method used in this assay is the UV-Vis spectrophotometry technique. The qualitative analysis was performed by adding the FeCl3 reagent. The results showed that the ethyl acetate fraction of clove leaves contained a total phenolic compound of 65.52 mg gallic acid equivalent per gram of extract (GAE/g). Thus, the ethyl acetate fraction of clove leaves is feasible to be developed as a source of phenolic compound.

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