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Ophthalmologica Indonesiana
Published by Perhimpunan Dokter Spesialis Mata Indonesia
ISSN : 01261193     EISSN : 2460545X     DOI : 10.35749
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Ophthalmologica Indonesiana is an open accessed online journal and comprehensive peer-reviewed ophthalmologist journal published by the Indonesian Ophthalmologist Association / Perhimpunan Dokter Spesialis Mata (PERDAMI). Our main mission is to encourage the important science in the clinical area of the ophthalmology field. We welcome authors for original articles (research), review articles, interesting case reports, special articles, clinical practices, and medical illustrations that focus on the clinical area of ophthalmology medicine.
Arjuna Subject : Kedokteran - Ophthalmology
Articles 852 Documents
 78   79   80   81   82 
CHOPPING METHODS IN APPROACHING HARD CATARACT: OPTIONS AND RECOMMENDATION: Oral Presentation - Observational Study - Ophthalmologist MUHAMMAD IQBAL; Haikal Hamas Putra Iqra
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/m8tx2q11

Abstract

Abstract Introduction & Objectives : Mature cataracts with hard-nuclear and soft-nuclear cataracts were different in their anatomical features and their management approach. Degeneration of zonules, loss of capsule and cortical liquefaction are often found in hard cataracts. Therefore, different approaches are required in this condition. Chopping methods have several advantages in managing the nucleus which plays a major part in cataract surgery. It lessened phaco power which minimized endothelial damage. The risk of intraoperative zonular dehiscence may also be lowered with chopping methods. Several chopping methods are widely accepted in approaching hard cataracts such as vertical chop, horizontal chop, crater and chop, drill and chop, stop and chop, and multilevel chop. Burst mode which requires high vacuum and power to chop and flow rates must be adequately comprehended by the surgeon in achieving the optimal result. This review discussed chopping methods in cataract surgery. Methods : Several chopping methods are widely accepted in approaching hard cataracts such as vertical chop, horizontal chop, crater and chop, drill and chop, stop and chop, and multilevel chop. Results : Burst mode which requires high vacuum and power to chop and flow rates must be adequately comprehended by the surgeon in achieving the optimal result. Conclusion : This review discussed chopping methods in cataract surgery.
THE DIFFERENCES OF MAXIMUM BLINK INTERVAL IN HYPERTENSION PATIENTS WITH AND WITHOUT DRY EYE DISEASE: Oral Presentation - Observational Study - Resident I NYOMAN CAHYA SETIABUDI; I Gusti Ayu Made Juliari; Cokorda Intro Dewiyani Pemayun
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/9v6e0z54

Abstract

Abstract Introduction & Objectives : Hypertension and the use of antihypertensive drugs are thought to be one of the risk factors for dry eye disease due to a decrease in tear production. Maximum blink interval (MBI), which is the time during which the eye can remain unblinking, can be an easy method for assessing dry eye disease because local conditions in the eye can affect blinking patterns. This study aims to determine the difference in the average MBI in hypertensive patients with dry eye disease and hypertensive patients without dry eye disease. Methods : This study is a cross-sectional analytic study which was conducted in January 2022-June 2022. The sample of the study was hypertensive patients with dry eye disease and without dry eye disease who were treated at the Internal Medicine Polyclinic, Kidney-Hypertension Division at Sanglah Hospital (Prof I.G.N.G. Ngoerah Hospital). The sample selection technique was consecutive sampling and the total sample in the study was 81 people. Data were collected using the OSDI questionnaire and TBUT and Schirmer examinations to assess dry eye disease, blood pressure tests to assess hypertension, and MBI examination. Results : The results showed that the average MBI in hypertensive patients with dry eye disease twice shorter than in hypertensive patients without dry eye disease (p<0.001). Conclusion : This shows that MBI can be used as a modality for screening and screening for dry eye disease in hypertensive patients. MBI can be an alternative for practitioners to objectively assess dry eye disease in primary health care where there is no complete ophthalmological facility.
OVERVIEW OF OCULAR TOXOPLASMOSIS IN DR KARIADI HOSPITAL SEMARANG: A 5-YEAR RETROSPECTIVE STUDY: Oral Presentation - Observational Study - Resident AMALIA DWI ARISKA; WINARTO REKI; DINA NOVITA
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/57cxkq73

Abstract

Abstract Introduction & Objectives : Ocular toxoplasmosis is the most common infectious etiology of posterior uveitis. The aim of this study is to describe the clinical characteristics of ocular toxoplasmosis in Dr. Kariadi Hospital, Semarang. Methods : A retrospective review of out-patient medical records of ocular toxoplasmosis at Dr. Kariadi Hospital Semarang from January 2018 to December 2022 was done. All toxoplasmic uveitis were included, whereas incomplete medical records and loss of follow-up were excluded. The clinical characteristics of patients were recorded and analyzed. Results : During 5 years a total of 160 patients were recruited of which 123 fulfilled the criteria, consisting of47 males (38.2%) and 76 females (61.8%), mostly were acquired infection (97.6%) with immunocompetent status (75.6%), and affected unilateral eye (65%). The predominant age was 26-45 years old (82.1%). Primary infection (70.7%) was greater than recurrent infection (10.6%) in which recurrence affects 46-65 years old (72.7%). Visual acuity at the initial presentation was <6/18-6/60 (26.2%), and the final follow-up increased to ≥6/18 (33.1%). Posterior uveitis (35.1%) with posterior pole lesion (66%) was a common clinical sign found. Medications given were trimethoprim-sulfamethoxazole (51,25%), and corticosteroid (27.5%) as an adjuvant. The complication detected was cataract (13%). Conclusion : Ocular toxoplasmosis was mostly found in immunocompetent female patients, acquired, unilateral, and in the posterior pole. A good response was found by trimethoprim-sulfamethoxazole and corticosteroid medications.
Trends of Diagnostic and Surgery of Intraocular Foreign Body: a 20 Years Review: Oral Presentation - Observational Study - General practitioner Nadya Eunice Sumolang; Venny D. Yolanda; Muhammad Ihsan
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/qnv95542

Abstract

Abstract Introduction & Objectives : Intraocular foreign bodies remain a common cause of ocular emergencies worldwide. Early and proper diagnostics and management are needed to reduce morbidity. In this paper, we reviewed the diagnostic and surgery trends of IOFB in the last 20 years. We aim to serve the update and better understand how to manage cases of IOFBs properly. Methods : We conducted a literature review on Scopus from 2002 to 2022 using the PRISMA method (assisted by the Watase UAKE application). We include imaging and surgery data in cases of metallic and non- metallic IOFB in the anterior, intralenticular, and posterior segments. Results : Thirty-one studies were included from Scopus and reference digging. We then classified the study into two main topics, surgery and diagnostic. In the last 20 years, imaging in diagnosis has been beneficial. CT-scan and MRI are still the leading options in visualizing metallic and non-metallic IOFB, respectively. However, in the case of tiny IOFB, MRI might be performed to visualize the metallic component with special considerations. IOCT also be considered to ensure no IOFB is left behind after removal. As for surgery, combining IOFB removal with pars plana vitrectomy remains the primary choice for IOFB in the posterior segment, combined with phacoemulsification and IOL implantation for the intralenticular and magnetic for the anterior segment. Combining two or more surgical techniques improves outcomes and prevents postoperative complications. Conclusion : A proper understanding of the components, location, and size of IOFB is required to determine the use of practical examinations and management of IOFB cases.
THE RELATIONSHIP BETWEEN DURATION OF GAS EMISSION EXPOSURE AND DRY EYE SYNDROME (DES) ON TAXIBIKE DRIVERS IN CENTRAL JAKARTA: Oral Presentation - Observational Study - General practitioner Muhammad Ferdiansyah; P. Rahmat Daeli; Alfoni Parsiska; Clarissa; M. Dwi Nugroho
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/v6y0td13

Abstract

Abstract Introduction & Objectives : Dry eye syndrome (DES) is a breakdown in the natural layer of tears that coats the front of the eye. Air quality in Jakarta indicated to be harmful to human health. The average annual PM 2.5 figure in Central Jakarta recorded 27.6 μg/m3. This figure is far beyond WHO standard that is 10 μg/m3. According to AAO one of the risk factors for dry eyes is exposure/injury to chemicals and the environment (dusty, windy, hot/dry). Therefore duration of traffic related air pollutions exposure may have an effect with the severity of dry eye syndrome on taxibike drivers in Central Jakarta. Methods : Analytic observation with cross sectional approach. Population was 196 taxibike drivers of Central Jakarta from April-May 2023. Data collection was by means of a questionnaire containing identity,informed consent,duration of exposure,and DES questions accordance with OSDI provisions. The results obtained are then recorded, aggregated, and entered into charts and tables. Hypothesis test used is chi-square. Results : There were 196 participated in this study. A total of 8 participants(4,1%) with >12hours duration of exposure experienced severe dry eyes, 18 participants(9.2%) experienced moderate, 102 participants(52%) experienced mild dry eyes and the rest was normal(34.6%). According to this, prevalence of DES was more frequent in taxibike drivers who worked 6-12hours more than in <6hours of worked (OR: 1.764) and the severity increased with duration of exposure(p<0.05). Conclusion : The duration of gas emission exposure has significant correlation with the frequency and severity of DES on taxibike drivers in Central Jakarta.
Appropriateness of Antibiotics Prescription for Conjunctivitis in Primary Health Care: A Literature Review: Oral Presentation - Observational Study - General practitioner Belinda Liliana; Atrika Fitri Nur Cahyani; Azura Nabila Putri; Oriana; Mohammad Eko Prayogo
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/ed988s41

Abstract

Abstract Introduction & Objectives : Conjunctivitis is one of the most common diseases present in primary health care (PHC) settings. The most common causes of conjunctivitis are viral infections and allergies. Despite this, patients diagnosed with conjunctivitis are often given antibiotics as therapy. Therefore, this literature review will assess the appropriateness of antibiotics prescription for patients with conjunctivitis in PHC settings. Methods : The authors performed an electronic literature search on databases PubMed and Scopus for eligible articles, which showed antibiotic prescription for patients with conjunctivitis in PHC settings and published between 2012 and 2022, then further sorted based on the inclusion and exclusion criteria. Results : A total of 8 studies met the inclusion criteria. Five studies showed high rates of inappropriate antibiotic prescriptions for patients with conjunctivitis in PHC. Several factors that might cause inappropriate prescription include the difficulty in determining the exact etiology, the need to fulfill patients’ satisfaction, the amount of experience and training doctors have received, consultation’s duration, stigma, the socio-demographic factors of the patient, the availability of treatment guidelines, and the availability of drugs. Some of the consequences that are concerned include the rise of antimicrobial resistance, stigma revolving around the usage of antibiotics for every infectious disease, and economic burden. Delays in prescribing antibiotics and proper training for general practitioners can be a solution to reduce inappropriate prescribing of antibiotics. Conclusion : Prescribing antibiotics for patients with conjunctivitis in PHC settings is mostly inappropriate
Development and application of targeted multiplex polymerase chain reaction to help diagnose infectious uveitis: Oral Presentation - Observational Study - General practitioner Rachel Ethelind
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/e3n7cx53

Abstract

Abstract Introduction & Objectives : Clinical pattern recognition is paramount in uveitis diagnosis. Pathogen detection from ocular fluid samples is often necessary to support infectious uveitis diagnosis, particularly in cases presenting with atypical clinical appearance. This study aims to present the process of developing targeted multiplex PCR and its application in infectious uveitis. Methods : This was a cross sectional study to evaluate the diagnostic performance of targeted multiplex PCR in infectious uveitis. We obtained ocular fluid samples and reviewed medical records of uveitis patients who underwent ocular fluid analysis at Cipto Mangunkusumo Hospital from February 2022 to March 2023. PCR detection threshold values (DNA copies/mL) were 10.9 for Mycobacterium tuberculosis (Mtb), 672 for Epstein-Barr virus, 4.77 for Cytomegalovirus, 6.37 for Toxoplasma gondii, and 5.53 for Herpes simplex virus. With every two-fold increase of pathogen selection, this method requires a half volume of extracted DNA template from aqueous/vitreous samples than uniplex PCR. The ophthalmologist selected the pathogen combination to be detected, allowing for a tailored examination. Results : Forty-seven aqueous or vitreous samples were analyzed. The positivity rate was 23.4% (11/47) with Mtb yielded the highest positivity (7/34; 20.6%). With final diagnosis as a reference, targeted multiplex PCR resulted in 32.3% sensitivity, 93.8% specificity, 90.9% positive predictive value and 19.2% negative predictive value. Conclusion : With its high specificity, targeted multiplex PCR is useful as a confirmatory but not screening tool in uveitis diagnosis. Ocular fluid analysis is an important part of stepwise diagnostic approach in uveitis.
TEAR FILM CHANGES FOLLOWING PHACOEMULSIFICATION SURGERY IN PRIMARY EYE CARE CENTER: Oral Presentation - Observational Study - Ophthalmologist TRI WAHYU
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/tq7ygj73

Abstract

Abstract Introduction & Objectives : Dry eye disease (DED) is one of the most commonly encountered problem in daily ophthalmology practice. One of many risk factors for DED is cataract surgery. Cataract surgery is known to modify tear film and ocular surface through corneal incision and ocular toxicity of peri- and postoperative medications. The aim of this study is to analyze tear film before and after phacoemulsification in primary eye care facility by measuring tear break-up time (TBUT), fluorescein staining, Schirmer I test (ST-I), and ocular surface disease index (OSDI) score. Methods : This was a longitudinal observational study with prospective cohort design, which included patients diagnosed with senile cataract and underwent uncomplicated phacoemulsification surgery at primary eye care center Sawangan Eye Clinic within period of June to December 2022. Friedman, Wilcoxon, and Cochran tests were used to analyze the data. Results : Thirty nine eyes from 39 patients met the inclusion criteria and were followed up to 3-month postoperatively. Mean age of the patients was 61.1±10.54 years, which consited of 53.8% males and 46.2% females. Mean preoperative OSDI score, corneal staining, TBUT, and ST-I were 24.94±10.24, 1.38±1.99, 2.94±2.17, and 15.46±8.80 respectively; while 3-month postoperative, these parameters’ means were 11.22±13.15 (p=0.0001), 1.38±2.56 (p=0.118), 3.13±1.79 (p=0.192), and 13.31±9.45 (p=0.006) respectively. OSDI was the only parameter which showed statistically significant changes from preoperative to postoperative follow ups (p<0.05). Conclusion : Phacoemulsification did not alter corneal staining and TBUT significantly after 3 months postoperatively, even though both of these parameters' preoperative value were already lower; yet OSDI score improved over time after surgery.
ADVANCED ADIPOSE PROTEIN EXTRACT PROMOTES LIMBAL STEM CELLS REGENERATION THROUGH STEM CELL NICHE MODULATION: Oral Presentation - Experimental Study - Ophthalmologist YUYUN RINDIASTUTI
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/cwgh3689

Abstract

Abstract Introduction & Objectives : Limbal stem cells (LSCs) play important role in maintaining corneal clarity. Disruption of LSCs or its niche may lead to LSCs deficiency that result in blindness. This study aimed to investigate therapeutic effect of advanced adipose protein extract (AAPE) in LSCs regeneration. Methods : AAPE was derived from adipose derived mesenchymal stem cell secretome purifed by ultrafiltration technique. 2D culture of LSCs were exposed by 0.25 NaOH, then treated with serum-free media as control group, media supplemented with 20% and 50% AAPE as treatment group I and II, respectively. MTT assay was conducted to measure cell proliferation and in vitro scratch assay to assess cell migration at 48 hours after treatment. EGF, FGF, HGF, and KGF from supernatant were measured by ELISA. Data was analyzed using One way ANOVA and post-hoc Tukey. Results : A 50% AAPE successfully promoted the highest proliferation and migration rate of LSCs compared to control group (94.38±2.51%, P 0.001; 68.52±3.51%, P 0.001). EGF (1216.67pg/mL), FGF (988.25pg/mL), HGF (119.33pg/mL), and KGF (793.25pg/mL) from 50% AAPE supernatant group were highest among other groups. Conclusion : A 50% AAPE demonstrated optimal beneficial effect on LSCs regeneration through upregulation of EGF, FGF, HGF, and KGF associated with niche modulation.
OSDI Score Comparison between Sodium Hyaluronate, Carboxymethylcellulose and Polyvinylpirrolidone for Dry Eye in Medical Student during Online Learning: Oral Presentation - Experimental Study - Ophthalmologist ARIANI RATRI DEWI
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/ezkb9720

Abstract

Abstract Introduction & Objectives : Online learning during COVID pandemic increase medical students’ screen time. Prolonged screen time is known as a risk factor for dry eye. Health problems during online learning such as those induced by dry eye could affect students’ academic performance. This study aim to find the best solution for dry eye in medical student during online learning by comparing three artificial tears eye drops, namely sodium hyaluronate, carboxymethylcellulose and polyvinylpirrolidone. Methods : This is an experimental study with 48 respondents divided into three treatment groups : sodium hyaluronate (SH), carboxymethylcellulose (CMC) and polyvinylpirrolidone (PVP). Each group consists of 16 respondents. Each respondents use their eyedrops six times daily in both eyes for two weeks. This study use Ocular Surface Disease Index questionnaire to evaluate dry eye. Data were analyzed using SPSS software, with p<0,05 is considered significant. Results : In SH group, mean OSDI score before treatment were 37,52 and after treatment 13,84 (p=0,001). In CMC group, mean OSDI score before treatment were 35,28 and after treatment 12,54 (p=0,000). In PVP group mean OSDI score before treatment were 38,17 and after treatment 13,15 (p=0,000). No significant differences of OSDI score was found between groups before treatment and after treatment (p=0,237). Conclusion : Sodium hyaluronate, carboxymethylcellulose and polyvinylpirrolidone eye drops could similiary improve dry eye symptoms significantly as measured by OSDI score in medical students during online learning.

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