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INDONESIA
Indonesian Journal of Science and Pharmacy
Published by Pustaka Media Publishing
ISSN : -     EISSN : 30255244     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Indonesian Journal of Science and Pharmacy (IJSP) accepts scientific articles as original research articles, short communication, reviews, and mini-reviews from anyone without any discrimination, as long as they submit articles that meet scientific principles. Indonesian Journal of Science and Pharmacy publishes various scientific articles covering Science and Pharmacy, Pharmaceutical Sciences. The following are the field within the scope of Indonesian Journal of Science and Pharmacy: Chemistry, Biology, Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Pharmaceuticals, Analytical Pharmacy-Medicinal Chemistry, Natural Product Development, Management Pharmacy, Clinical-Community Pharmacy, Microbiology Pharmacy.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 6 Documents
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Search results for , issue "Vol. 1 No. 1 (2023): Indonesian Journal of Science and Pharmacy" : 6 Documents clear
Determination of Total Alkaloid Content of Raru (Cotylelobium lanceolatum Craib) Bark Extract Using UV-ViS Spectrophotometry Method cici andriani; Anny Sartika Daulay; Ridwanto Ridwanto; Haris Munandar Nasution
Indonesian Journal of Science and Pharmacy Vol. 1 No. 1 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

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Abstract

The raru plant (Cotylelobium  lanceolatum Craib) comes from the Dipterocarpaceae family. Raru bark is usually added to the wine to enhance the taste of the wine. raru bark has antidiabetic compounds as a lowering of sugar levels in the blood. The purpose of this study was to determine the alkaloids in the Raru plant (Cotylelobium   lanceolatum  Craib) and to determine the total alkaloid content found in the Raru plant (Cotylelobium  lanceolatum  Craib). The extraction method used is the maceration extraction method using methanol solvent with various concentrations which is then evaporated with a rotary evaporator. Whereas the quantitative test was carried out by means of the viscous extract obtained by adding 2 mL of Phosphate buffer with a pH of 4.7, 2 mL of bromocresol green (BCG), and measured at a wavelength of 272.705 nm. The yield of the extract from a concentration of 95% was 23.0779%, a concentration of 70% was 21.2144%, a concentration of 50% was 20.3274%. The correlation equation obtained from the caffeine curve is y = 0.0508X + 0.008 and the value of r = 0.999, and the levels of alkaloids with different extract concentrations. Actual alkaloid content in raru bark methanol extract 95% was 14.9094 ± 0.3697 mg/g, actual alkaloid content in raru bark methanol extract 70% was 10.0472 ± 0.4594 mg/g, actual alkaloid content in extract 50% raru bark methanol was 6.6260 ± 0.803.
Effectiveness Test of Sidaguri Leaf Ethanol Extract Gel (Sida rhombifolia L.) on the Cealing of Degree IIA Burn in Male Rabbits Bazlina Adani; Gabena Indrayani Dalimunthe; Minda Sari Lubis; D Elysa Putri Mambang
Indonesian Journal of Science and Pharmacy Vol. 1 No. 1 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

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Abstract

Burns are one of the incidents that often occur in society. Currently, the use of burn medicine is very limited, in terms of the cost of treatment and healing is relatively expensive. In this case, the use of natural plants is needed as a treatment for burns on the skin, namely sidaguri leaves. Researchers want to take advantage of secondary metabolites contained in sidaguri leaves and formulate them into pharmaceutical preparations in the form of a gel. The purpose of this study was to determine the content of secondary metabolites in the ethanolic extract of sidaguri leaf and to determine the effectiveness of the gel preparation of the ethanolic extract of sidaguri leaf (Sida rhombifolia L.) on the healing of burns. This research includes simplicia characterization, phytochemical screening, gel evaluation and test the effectiveness of sidaguri leaf extract gel. HPMC negative control group, 1% EEDS, 3% EEDS, 5% EEDS and bioplacenton positive control group. The parameters tested were the diameter of the burn for 14 days. The research data were analyzed using the One-Way ANOVA (Analysis of Variance) method followed by the Tukey test. The results of this study obtained EEDS 5% and bioplacenton did not have a significant difference in the healing of burns in male rabbits on day 14.  It can be concluded that the ethanolic extract gel of sidaguri leaves has effectiveness on healing burns with a dose of 5% EEDS concentration.
Simplicia Characteristics and Phytochemical Screening of Buni Fruit (Antidesma bunius L. Spreng) Anggitha Ningtias; Zulmai Rani
Indonesian Journal of Science and Pharmacy Vol. 1 No. 1 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

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Abstract

ABSTRACT Buni fruit is a plant that produces secondary and antibacterial metabolites. The purpose of this study was to identify the characteristics of the berry simplicia and the content of phytochemical compounds in the berry fruit. Starting with the maceration method using 96% ethanol, this study carried out phytochemical screening and characterization tests. The results of the phytochemical screening study showed that compounds such as flavonoids, tannins, saponins, alkaloids, and steroids were found in the ethanol extract of buni fruit. Due to the simplicia characterization, we found a water content of 9.3%, a water-soluble extract of 11.51%, an ethanol-soluble extract of 17.19%, a total ash content of 8.1%, and an acid-insoluble ash content (0.7 %).        
Level of Patient Satisfaction with Pharmaceutical Services in Pasar Ujungbatu Padang Lawas Health Center in 2023 Hasni Yaturramadhan Harahap; Debi Meilani
Indonesian Journal of Science and Pharmacy Vol. 1 No. 1 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

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Abstract

Quality pharmaceutical services are health services that can satisfy every service user in accordance with the level of patient satisfaction and the administration is in accordance with the established code of ethics and service standards. The purpose of this study was to determine the level of patient satisfaction with pharmaceutical services at the Pasar Ujungbatu Health Center, Padang Lawas Regency, Padang Lawas Regency in 2023. The research method included a descriptive method, namely using a quantitative approach to determine the level of patient satisfaction with pharmaceutical services at the Ujungbatu Market Health Center, Padang Lawas Regency. The results showed the level of patient satisfaction with pharmaceutical services at Pasar Ujungbatu Padang Lawas Health Center in 2023 with a total of 240 respondents, namely 2 people were very dissatisfied (0.83%), 4 people were dissatisfied (1.66%), 34 people were quite satisfied (14.16), 162 people were satisfied (67.5%), and 38 people were very satisfied (15.85%).
Analysis of Sodium Benzoate Content in the Market Soft Beverages Using Uv-Vis Spectrophotometry Method Windi Hari Akbar; Ainil Fithri Pulungan; Ridwanto Ridwanto; Anny Sartika Daulay
Indonesian Journal of Science and Pharmacy Vol. 1 No. 1 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

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Abstract

Sodium benzoate is one of the preservatives that are permitted to be used in food and beverages. Research has been carried out with the aim of knowing that carbonated drinks contain the preservative sodium benzoate, knowing the amount of sodium benzoate in soft drinks and to find out the levels of sodium benzoate in soft drinks fulfilling the maximum usage requirements according to BPOM RI Head Regulation No. 36 of 2013. This study used the uv-vis spectrophotometry method. To determine the preservative content of sodium benzoate, a qualitative test was first carried out on the sample using the color reaction method and esterification test. To determine the levels using a UV-Vis spectrophotometer at a wavelength of 269 nm with ethanol p.a as a solvent. The results of the qualitative test using the color reaction method showed that the three samples of soft drinks positively contained the preservative sodium benzoate. To validate this, an esterification test was carried out on the three samples and they produced the smell of Ambon bananas which proved that the three samples positively contained sodium benzoate. For the quantitative test using the Uv-Vis spectrophotometry method at a wavelength of 269 nm using ethanol p.a as a solvent. The results of the analysis showed that the preservative content of sodium benzoate which was calculated for each sample was for a soft drink sample a: 244.93 ± 19.9349 mg/kg. Soft drinks b: 65.3 ± 0 mg/kg, soft drinks. Soft drinks c: 78.6 ± 13.1291 mg/kg. Based on these results, it can be concluded that the levels of sodium benzoate in samples A, B, and C met the standard requirements for maximum usage limits, namely not more than 600 mg/kg.
Effect of Extraction Method on Yellow Wood Rendement and Phenolic Content (Arcangelisia flava (L.) Merr) UV-Vis Spectrophotometry Extract of Ethanol Merida Sasnita; Anny Sartika Daulay; Ridwanto Ridwanto; Haris Munandar Nasution
Indonesian Journal of Science and Pharmacy Vol. 1 No. 1 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

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Abstract

Indonesia is a country rich in biodiversity. With the wealth of natural resources, there is very much that can be used from flora and fauna to treat various diseases, yellow wood is one of the plants that have medicinal properties and has not been widely studied, yellow wood is efficacious as antimicrobial, antioxidant, antihyperlipidemia, and anticancer. The objective of this study was to determine the class of chemical compounds found in simplicial and extracts of yellow wood plants and to determine the effect of extraction methods on the yield and phenolic levels of ethanol extracts of yellow wood plants. The stages of this research include processing plant materials, making maceration extracts and socletation of yellowwood plants, examination of characteristics, phytochemical screening and determination of total phenolic levels of ethanol extract 96% maceration and socleation of yellow wood (Arcangelisia flava (L.) Merr) by UV-Vis Spectrophotometry method. The highest yield research results are found in the maceration extract yield, this is because the maceration process time is shorter than the socleation process, so that the compound withdrawal process carried out by maceration is more optimal than the socleation method. In addition, the more solvent used, the more extracts produced. The determination of total phenolics is performed by determining the maximum wavelength of gallic acid using UV-Vis spectrophotometry methods. Yellowwood maceration ethanol extract has a total phenolic content of 22.0087 ± 0.8567 mg GAE/g and socleation extract has a total phenolic content of 18.2023 ± 0.1434 mg GAE/g.

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