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All Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan Biomedical Journal of Indonesia Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Bioscientia Medicina : Journal of Biomedicine and Translational Research Scientia Psychiatrica Open Access Indonesia Journal of Social Sciences Sriwijaya Journal of Ophthalmology Eureka Herba Indonesia Indonesian Community Empowerment Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Open Access Indonesia Journal of Social Sciences Journal of Anesthesiology and Clinical Research
Patricia Wulandari
Cattleya Mental Health Center, Palembang, Indonesia
Religion Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Utilization of Health Consultation Application (Chat Dokter Online) for COVID-19 Self-Isolation Patient Services in Palembang City Rachmat Hidayat; Patricia Wulandari
Indonesian Community Empowerment Journal Vol. 2 No. 2 (2022): Indonesian Community Empowerment Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/icejournal.v2i2.15

Abstract

Chat Dokter Online is a digital health platform developed by CV Cattleya Consultation Center based in Palembang. This digital health platform serves general public health consultations regarding health problems both in the city of Palembang and from outside the city of Palembang. This application is expected to be able to provide optimal services and a broad reach for users and especially patients who are self-isolating COVID-19 in Palembang City. The implementation of this community service activity is carried out through the stages of observation, interviews, application prototype development, application testing, application utilization, and monitoring application utilization. Chat Dokter Online provides massive health services and easy access for patients exposed to COVID 19 to determine the clinical degree of COVID-19, complaints felt by patients and to determine when to finish self-isolation. In addition, this application helps the public to get valid health information directly from doctors and experts.
The Importance of Nutrition, Immunization, and Stimulation of the First 1000 Days of Life for Health, Multiple Intelligences, and Reducing Malnutrition Rates in Toddlers in Barugbug Village, Jatisari, Karawang Rachmat Hidayat; Patricia Wulandari
Indonesian Community Empowerment Journal Vol. 2 No. 1 (2022): Indonesian Community Empowerment Journal
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/icejournal.v2i1.16

Abstract

Nutrition and health problems are problems that are still an iceberg phenomenon in Indonesia. It can be seen in big cities like Jakarta which still have quite a lot of health problems. Nutritional problems in Indonesia continue to increase from year to year. These nutritional and health problems will affect the health of infants and toddlers. This community service program is expected to increase public knowledge and insight regarding the importance of nutrition, immunization, and stimulation in the first 1000 days of life, reduce malnutrition rates in toddlers, and fulfill health facilities and infrastructure in Barugbug Village. The community service program that will be carried out will be directed at the importance of nutrition, immunization, and stimulation in the first 1000 days of life for health, multiple intelligence and reducing malnutrition rates in toddlers in RT 01 RW 05 Barugbug Village, Jatisari District, Karawang, West Java. This activity was carried out for 5 months. The series of activities carried out in this program include counseling, mobile posyandu, KPSP (Pre-Development Screening Questionnaire), nutrition consultation, direct practice of child stimulation, advocacy, and TOT (Training Of Trainers). The results of the implementation of this program are an increase in public knowledge which can be measured by the results of the pretest and posttest, the reduction in the number of under-nutrition in children under five which can be measured by conducting mobile posyandu and monitoring nutritional status, increasing the intelligence of multiple children by conducting the KPSP (Pre-screening Development Questionnaire) and Practicing directly stimulates children, improves health status through nutrition consultations, makes use of health facilities and infrastructure through advocacy addressed to the Karawang Regent, and conducts TOT (Training Of Trainers) for puskesmas staff, village midwives, and village cadres for the sustainability of our program.
Biomolecular Aspects of Schizophrenia Patricia Wulandari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 3 No. 2 (2019): Bioscientia Medicina: Journal of Biomedicine and Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v3i2.88

Abstract

Abstract Schizophrenia is a common psychiatric disorder, which is characterized by severe distortion of reality; disturbances in thoughts, feelings and behavior; according to DSM V is a disorder form deviations fundamentals and characteristics of thought and perception, and by the innapropriate or blunted affect. The influence of genetics is believed to have a role in psychiatric disorders, especially if the disorder has occurred in young adults or adolescents. The pathophysiology of schizophrenia is closely related to disorders of the biomolecular aspects of the central nervous system. Dopamine activity in the striatal area and prefrontal cortex is a mechanism believed to be the cause of the emergence of positive and negative symptoms in schizophrenia. Meanwhile, neuronal cell apoptosis and increased oxidants, especially in the basal ganglia and prefrontal cortex areas cause worsening of negative symptoms experienced by schizophrenic patients.
Methods of Selection and Maintenance of Experimental Animals for Biomedical Research Rachmat Hidayat; Patricia Wulandari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 1 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i2.227

Abstract

A B S T R A C TResearch is an activity carried out based on scientific principles and methodssystematically to obtain information, data, and information from relatedsubjects, with understanding the theory and proving assumptions and / orhypotheses. The results obtained are conclusions that can be applied orbecome additional knowledge for the progress of science. However, researchactivities must still respect the rights and dignity of research subjects.Health research includes biomedical, epidemiological, social, and behavioralresearch. Some health research can be done in vitro, using mathematicalmodels, or computer simulations. If the research results are to be used forhumans, further research is needed using living materials (in vivo) such ascell lines and tissue cultures. However, to observe, study, and conclude alloccurrences in living things as a whole, experimental animals are neededbecause experimental animals have a value for each part of the body andthere are interactions between these body parts.
Enzyme Linked Immunosorbent Assay (ELISA) Technique Guideline Rachmat Hidayat; Patricia Wulandari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 5 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i5.228

Abstract

ELISA (Enzyme-linked immunosorbent assay) is a technique used to assess the quantification of peptide, protein, antibody and hormone levels, based on the principle of antigen-antibody binding. In the ELISA technique, antigen immobilization will be carried out on a solid surface, then bound with antibodies to form an antigen-antibody bond complex, where the antigen-antibody complex is bound to the enzyme. The detection signal in the form of a color change will be formed due to the reaction between the enzyme and the substrate.
Western Blotting (WB) Technique Guideline for Separation and Isolation of Protein Rachmat Hidayat; Patricia Wulandari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 4 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v5i4.229

Abstract

Western blotting is an important technique used in cell and molecular biology. Using the western blot, researchers can identify specific proteins from the complex mixture of proteins extracted from cells. This technique uses three elements to accomplish this task: (1) separation by size, (2) transfer to a solid support, and (3) marking target proteins using appropriate primary and secondary antibodies to visualize. This paper will attempt to explain the techniques and theory behind western blot, and offer several ways to solve the problem
Preclinical Test Methods with Animal Mouse and Rats Biomedical Research: Technical Guideline Rachmat Hidayat; Patricia Wulandari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 2 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i2.232

Abstract

A B S T R A C TTrials in pre-clinical trials are very complex multidisciplinary studies. Extrapolatingdata from animals to humans requires information from many fields of science. Frompre-clinical trials, more detailed information and data on efficacy and safety wereobtained, especially at doses equivalent to doses in humans, and the presence orabsence of cumulative effects and whether these effects could return to normal(reversible) after the administration of the test material was stopped. This test canbe used to predict the negative impact on humans if he is exposed to the materialfor a long time.
Euthanasia Procedure of Animal Model in Biomedical Research Rachmat Hidayat; Patricia Wulandari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 6 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i6.310

Abstract

Regardless of the method, it is essential to induce unconsciousness as rapidly as possible if euthanasia is to be aesthetically and scientifically successful. Criteria that have been considered in recommending the methods of euthanasia include: time required to produce unconsciousness, time required to produce death, purposes, research results and compliance with the AVMA Guidelines on Euthanasia. There are special considerations for euthanizing rodent embryos, fetuses and neonates.
Protocol for Anesthesia Animal Model in Biomedical Study Rachmat Hidayat; Patricia Wulandari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 7 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i7.311

Abstract

Recognition of pain depends upon intact pathways from pain receptors to the thalamus and cerebral cortex, as well as functional cerebral cortex and subcortical structures. Thus any means that renders the cerebral cortex nonfunctional, such as hypoxia or drug depression, prevents pain. When this happens, stimuli that evoke motor nerve reflexes that may be painful to the conscious animal are not painful in the unconscious animal. Equally painful stimuli administered to animals chemically paralyzed by curare or succinylcholine will not evoke a motor reflex simply because of paralysis, but will cause pain because of the conscious state. Hence, it is possible that unconscious animals may feel no pain but respond to certain stimuli, and paralyzed animals may feel pain but cannot respond.
Fluid and Drug Administration Procedure Animal Model in Biomedical Research Rachmat Hidayat; Patricia Wulandari
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 8 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i8.312

Abstract

Drugs, vaccines, injectable anesthetics or other agents are to be administered, one or more of several different routes may be selected. The routes selected are governed by the nature of the agent being administered, the animal, the purpose of the administration and other factors.
Co-Authors Andrian F Kusumadewi Budi Pratiti Budi Pratiti Carla R Marchira Carla R Marchira Carla Raymondalexas Marchira Cecep S Kristanto Edith Humries Ester G Panserga Farouk, Husnil Rachmat Hidayat RACHMAT HIDAYAT Rarum, Anovy Ridwan, Hibsah Shinta Anggraini, Shinta Zahra D Khan