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All Journal Biology, Medicine, & Natural Product Chemistry Window of Health : Jurnal Kesehatan JURNAL PENDIDIKAN TAMBUSAI Jurnal Ilmiah Profesi Pendidikan WoCDJ Journal La Medihealtico MAHESA : Malahayati Health Student Journal INDONESIAN JOURNAL OF HEALTH WAL'AFIAT HOSPITAL JOURNAL
Makmun, Armanto
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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The Potential of a Sumbawa Herbal Oil-Based Oleogel as Burn Wound Dressing Yuniar, Andi Irma; Yasid, Nurul Wahidah; Nissatuljannah, Syarifah Fatimah; Rijal, Syamsu; Makmun, Armanto
Biology, Medicine, & Natural Product Chemistry Vol 12, No 2 (2023)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2023.122.559-562

Abstract

This study aimed to innovate the current Sumbawa oil preparation which is still in the form of liquid into an oleogel so that it is easier to apply and more practical for distribution and storage. Phytochemical analysis of Sumbawa oil showed the contents of phenols, flavonoids, and alkaloids. By adding hydroxyethyl cellulose (HEC) as a gelling agent and glycerin as a humectant, Sumbawa oil can be served in the form of an oleogel. The pH measurement of the Sumbawa oil oleogel at levels of 90%, 95%, and 100% ranged from 7.0–7.3 which is the ideal acidity level for the wound healing process. In the antimicrobial activity test with S. aureus and E. coli, the zone of inhibition ranged from 12.1–14.7 mm which is considered strong. Meanwhile, in in vitro testing of the anti-inflammatory activity using the human red blood cell membrane stabilization method, the stability level of each was obtained to be 78% for 100% Sumbawa oil, 74% for oleogel with 95% Sumbawa oil, and 73% for oleogel with 90% Sumbawa oil. The oleogel morphology observation using a scanning electron microscope showed a good gelation process at 5% and 10% HEC levels.
Co-Authors Adriansyah, Aan Afrayani, Wirna Aisyah, Windi Nurul Alamanda Irwan, Andi Andi Mappaware, Nasrudin Arsa, Sri Asmawati Aryanti Aryanti Bamahry, Aryanti Cahyani, Pramesty Regita Daeng Kanang, Indah Lestari Dahliah, Dahliah Darma, Sidrah Dase, Jerny El Firman, Andi Mappaita Fakhirah, Muthiah Raghdah Gani, Azis Beru Hamzah, Firmansyah Hamzah, Pratiwi Nasir Ida Royani Kamaluddin, Irna Diyana Kartika Karim, Marzelina Kartika K, Irna Diyana Kartika, Andy Visi Kurniyanti, Novia Mathius, Denny Mokhtar, Shulhana Muhammad Irsan Mursyid, Muhammad Nesyana, Nesyana Ningsi, Iin Widya Ningsih, Iin Widya Nissatuljannah, Syarifah Fatimah Nurdin, Abbas Zavey Nurwahyuni Parningan, Zherant Paulus Paulus Purnama, Indah Dian Riyanti, Nabilah Sri Vitayani Sulvita Karsa, Nevi Syamsu Rijal Syamsu, Rachmat Syatirah, Andi Bau Wijaya, Fanny Yanti, A Kartini Eka Yasid, Nurul Wahidah Yuniar, Andi Irma Yusril, Moh. Zulfitriani Murfat