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All Journal HAYATI Journal of Biosciences Public Health of Indonesia Journal of Nursing and Health (JNH) Akper Yakpermas Banyumas JURNAL ANALIS KESEHATAN KENDARI (JAKK)
Fusvita, Angriani
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Agriculture, Biological Sciences & Forestry Earth & Planetary Sciences Health Professions Nursing Public Health

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IDENTIFIKASI BAKTERI ASAM LAKTAT (BAL) DAN KADAR ALKOHOL PADA AIR TAPE KETAN HITAM Fusvita, Angriani; idris, sri aprilianti; Fitriani, Fitriani
Journal of Nursing and Health Vol. 9 No. 3, September (2024): Journal of Nursing and Health
Publisher : Yakpermas Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52488/jnh.v9i3, September.370

Abstract

Tape adalah makanan tradisional yang dibuat melalui proses fermentasi yang melibatkan ragi. Tape bervariasi tergantung bahan dasar yang digunakan salah satu diantaranya adalah beras ketan hitam. Proses fermentasi akan menyebabkan perubahan pada sifat subsrat yang akan menimbulkan rasa asam, bau alkohol dan rasa khas. Salah satu bakteri yang dapat membantu proses fermentasi yaitu bakteri asam laktat (BAL) yang merupakan kelompok bakteri probiotik yang sangat bermanfaat bagi kesehatan manusia. Penelitian ini bertujuan untuk mengetahui adanya Bakteri Asam Laktat (BAL) dan Kadar Alkohol pada Air Tape Ketan Hitam. Metode Identifikasi bakteri dengan melakukan pewarnaan Gram dan uji Biokimia menggunakan alat Vitek 2 Compact serta metode Destilasi untuk mengukur kadar alkohol dengan sampel yang digunakan pada fermentasi hari ke 3, ke 4, dan ke 5. Hasil penelitian terhadap sampel pada fermentasi hari ke 3, ke 4, dan ke 5 ditemukan adanya Bakteri Asam Laktat (BAL) yaitu Enterococcus faecium dan kadar alkohol tertinggi terdapat pada fermentasi hari ketiga yaitu sebesar 40,77 %.
Diabetes Mellitus and Bacterial Infections: A Review of Main Infections in DM Patients Yunus, Reni; Wijayati, Fitri; Askrening, Askrening; Rahayu, Dian Yuniar Syanti; Hasan, Fonnie E; Trees, Trees; Fusvita, Angriani
Public Health of Indonesia Vol. 10 No. 1 (2024): January - March
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v10i1.777

Abstract

Millions of single-celled microscopic organism called bacteria reside within the human body. Numerous infectious diseases in humans are caused by some of these pathogen bacteria. One of the major risk factors for bacterial infections is diabetes mellitus. Bacterial infections and diabetes may have a reciprocal relationship in which some illnesses exacerbate insulin resistance. Diabetes may occur as a result of bacteria in the digestive system. Any organ in a human body can become infected by bacteria. The respiratory tract, gastrointestinal tract, urinary tract, skin, and soft tissues are the most frequently infected areas with diabetes. Uncontrolled hyperglycemia increases the risk of bacterial infections by impairing innate and adaptive immune responses. Furthermore, skin ulceration can result from long-term diabetic consequences such peripheral vascular disease and neuropathy (sensorimotor and autonomic). These conditions can also lead to secondary bacterial infections.
UJI DAYA HAMBAT EKSTRAK DAUN PATIWALA (Lantana camara L)TERHADAP PERTUMBUHAN BAKTERI Streptococcus mutans ATCC 25175 Afdillah, Nia; Fusvita, Angriani; Febriyani, Rani
Jurnal Analis Kesehatan Kendari Vol. 6 No. 1 (2023): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 6 (1) Desember 2023)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v6i1.289

Abstract

ABSTRACT Indonesia has high natural resources and biodiversity, consisting of a number of islands with 34 provinces that have a variety of ethnicities and cultures. Medicinal culture has been proliferating since ancient times which has been preserved from generation to generation. This traditional medicine can be used as a medicine and around 300 types have been utilized for traditional medicinal ingredients.This study was to determine the patiwala leaf extract and its concertation in inhibiting the growth of Streptococcus Mutans bacteria. This research is a labolatory experimental research witch is a quqntitative study. This research method is to explain the cause and effect between one variable and another variable. This research was conducted using 2 methods of the kruskallwallis test and the normality test with the help of the SPSS application. The result of the Kruskallwallis test and normality text with normal result with values (p>0,41) and (p<0,01). Patiwala leaf extract (Lantana camara L) has different abilities against the growth of Streptococcus Mutans bacteria. Keywords : Patiwala Leaves, Lantana camara L, Inhibition ABSTRAK Indonesia memiliki sumber daya alam dan keanekaragaman hayati yang tinggi, terdiri dari jumlah pulau dengan 34 provinsi yang memiliki beranekaragaman suku dan budaya. Budaya pengobatan sangat berkembang sejak dulu yang sangat dilestarikan secara turun-temurun. Pengobatan tradisional ini dapat digunakan sebagai obat dan sekitar 300 jenis yang sudah di manfaatkan untuk bahan obat tradisional. Penelitian ini adalah untuk mengetahui ekstrak daun patiwala dan konsentrasi dalam menghambat pertumbuhan bakteri Streptococcus Mutans. Penelitian ini adalah penelitian eksperimen laboratorium merupakan suatu penelitian kuantitatif. Metode penelitian ini yaitu menjelaskan sebab akibat bahwa antara satu variable dengan varibel lainya. Penelitian ini di lakukan dengan menggunakan 2 metode uji kruskall wallis test dan uji normalitas dengan bantuan aplikasi SPSS. Hasil uji kruskall wallis test dan uji normalitas dengan hasil normal dengan nilai (p<0,41) dan (p<0,01). Ekstrak daun patiwala (Lantana camara L) yang memiliki kemampuan yang brbeda-beda terhadap pertumbuhan bakteri Streptococcus mutans Kata Kunci: Daun patiwala, Lantana camara L, Daya hambat
Secondary Metabolite Compounds from Alpinia monopleura Extract and Evaluation of Anti-Inflammatory Activity based on In Vitro and In Silico Studies Yodha, Agung Wibawa Mahatva; Badia, Esti; Musdalipah; Reymon; Fauziah, Yulianti; Fusvita, Angriani; Arfan; Wahyuni; Sahidin
HAYATI Journal of Biosciences Vol. 31 No. 6 (2024): November 2024
Publisher : Bogor Agricultural University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.4308/hjb.31.6.1154-1164

Abstract

Alpinia monopleura is one of the endemic plants of Sulawesi, and it has an extensive distribution in the region. Research on chemical compounds and biological activities of A. monopleura is essential to continue as an effort to support the utilization of native plants for medicine. The extract was obtained using the maceration method. The chemical compounds in the extract were identified using Liquid Chromatography Mass Spectrometry (LCMS). Bovine Serum Albumin (BSA) and molecular docking methods were used to evaluate the anti-inflammatory activity. Ten compounds contained in the extract were successfully identified, E-para-coumaric acid (1), trans-ferulaldehyde (2), 3,5,6-trihydroxy-4',7-dimethoxyflavone (3), nevadensin (4), malvalic acid (5), ent-16α,17-hydroxy-19-kauranoic acid (6), 3′,5-dihydroxy-7,4'-dimethoxy flavone (7), saurufuran B (8), 5-hydroxy-7,8,2'-trimethoxyflavanone (9) and dehydroabietic acid (10). The anti-inflammatory activity of extracts from rhizomes and stems of A. monopleura were 8.62 and 10.59 mg/L, respectively. Some flavonoids (9 and 7) can bind strongly to specific residues around the COX-2 active site, such as Ser530, thereby interfering with the function of the COX-2 enzyme and reducing the production of pro-inflammatory prostaglandins. Thus, A. monopleura extract has the potential to inhibit inflammatory responses through molecular regulation of the COX-2 enzyme.
Co-Authors Afdillah, Nia Arfan Askrening Badia, Esti Fauziah, Yulianti Febriyani, Rani Fitriani Fitriani Hasan, Fonnie E Idris, Sri Aprilianti Musdalipah Rahayu, Dian Yuniar Syanti Reni Yunus, Reni Reymon Sahidin Trees, Trees WAHYUNI Wijayati, Fitri Yodha, Agung Wibawa Mahatva