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All Journal Farmasis: Jurnal Sains Farmasi EJOIN : Jurnal Pengabdian Masyarakat
Indalifiany, Astrid
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Religion Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health

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Preparation and Characterization of Ethanol Extract of Spons Xestospongia sp. Indalifiany, Astrid; Sahidin, Sahidin; Wahyuni, Wahyuni; Fristiohady, Adryan; Sadarun, Baru; Andriani, Rina; Aspadiah, Vica Aspadiah; Naimah, Naimah
FARMASIS: Jurnal Sains Farmasi Vol 2 No 1 (2021): Farmasis : Jurnal Sains Farmasi
Publisher : Universitas PGRI Adi Buana, Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v2i1.3542

Abstract

Background: Xestospongia sp. is a species of the Demospongiae class that can be used as a medicinal substance. Xestospongia sp is known to have various activities such as anticancer, antibiotic, anti-fungal, cardiotonic, and antimalarial. One of the ways to make the formulation of natural ingredients is the phytosome vesicle technique. This method can be used to increase the penetration of compounds through cell membranes, increase their absorption and increase its bioavailability in the body. Objective: The aim of this study was to obtain the optimum phytosome composition in the ethanol extract of Xestospongia sp. and phosphatidylcholine with approprite vesicle characteristics. Methods: The preparation was carried out by varying the extract and phosphatidylcholine with a thin layer hydration method at a ratio of 1:1, 1:2, 2:1, and 2:2 and and phytosome characterization was carried out in each of these formulas to obtain the optimal formula. Results: In this study, the optimum phytosome formula has met the criteria based on morphological test parameters using an optical microscope obtained by spherical morphology, stability of physical appearance observations stored at 2oC-8oC ± 1oC temperature, pH measurement using a pH meter obtained a pH value of 4.20, and particle size determination using the Particle Size Analyzer (PSA) obtained a particle size of 180.6 nm and particle distribution value (IP) of 0.133. Conclusion: Composition of the optimum phytosome formula in the ratio of extract and phosphatidylcholine 1: 1 with the LUV phytosome category (Large Unilamellar Vesicle)
EDUKASI PENCEGAHAN PENYAKIT DIARE DI SDN 94 KENDARI Jabbar, Asriullah; Solo, Dian Munasari; Nasrudin, Nasrudin; Wahyuni, Wahyuni; Indalifiany, Astrid; Halik, Halik; Hafizhah, Hafizhah; Kasmawati, Kasmawati; R, Nurcahyani Pratiwi; Rahman, Rahman; Muslifah, Wa Ode; Mubarak, Mubarak; Y, Muhammad Ilyas
EJOIN : Jurnal Pengabdian Masyarakat Vol. 2 No. 7 (2024): EJOIN : Jurnal Pengabdian Masyarakat, Juli 2024
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/ejoin.v2i7.3133

Abstract

Diare adalah peningkatan pengeluaran tinja dengan konsistensi lebih lunak atau lebih cair dari biasanya, dan terjadi paling sedikit 3 kali dalam 24 jam. Sementara untuk bayi dan anak-anak, diare didefinisikan sebagai pengeluaran tinja >10 g/kg/24 jam. Diare dapat mengakibatkan penurunan nafsu makan, sakit perut, rasa lelah, hingga penurunan berat badan. Diare juga dapat mengakibatkan kehilangan cairan elektrolit secara mendadak sehingga mengakibatkan penderita mengalami komplikasi seperti dehidrasi, kerusakan organ. Tujuan pengabdian ini adalah untuk mengedukasi siswa SDN 94 Kendari tentang penyakit diare dan pencegahannya yaitu dengan cara mencuci tangan dengan baik dan benar, tidak jajan sembarangan, menjaga kebersihan lingkungan. Metode yang digunakan pada kegiatan ini adalah presentasi materi, tanya jawab antara pemateri dan siswa SD serta menggunakan poster sebagai media pengingat kepada siswa-siswi mengenai pencegahan penyakit diare. Dengan adanya kegiatan pengabdian ini siswa-siswi SDN 94 Kendari terpapar informasi mengenai penyakit diare dan cara mencegah penyakit diare
Co-Authors Andriani, Rina Aspadiah, Vica Aspadiah Baru Sadarun Fristiohady, Adryan Hafizhah, Hafizhah Halik, Halik Jabbar, Asriullah Kasmawati Kasmawati Mubarak Mubarak Muslifah, Wa Ode Naimah Naimah Nasrudin R, Nurcahyani Pratiwi Rahman Rahman Sahidin Sahidin Solo, Dian Munasari wahyuni wahyuni Y, Muhammad Ilyas