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Faktor yang Berhubungan dengan Long-term COVID-19: Studi Observasi Cross-Sectional di Indonesia Arina Dery Puspitasari; Nanda Ardianto; Lily Aina; Eunice Marlene Sicilia Kundiman; Fatimatuz Zahra Oviary Satryo; Melinda Putri Amelia Rachman; Fauzul Meiliani; Pharmasinta Putri Hapsari; Bambang Subakti Zulkarnain; Alfian Nur Rosyid; Tamara Nur Budiarti; Brigitta Dhyah Kunthi Wardhani
WMJ (Warmadewa Medical Journal) Vol 7 No 1 (2022): May 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.1.4784.33-39

Abstract

Long-term COVID-19 could occur in COVID-19 patients, affecting the patient's quality of life, and becoming a problem for public health. However, information is rarely on factors associated with the occurrence of long COVID-19 cases. This study analyzed factors associated with long-term COVID-19. The study was an observational cross-sectional, conducted in August 2021. The data were collected through a Google form questionnaire distributed to COVID-19 survivors in Indonesian. They must be aged more than 17 years to meet the inclusion criteria, while those with incomplete data were excluded. The data were processed by using SPSS 21 with an ordinal regression test in which an alpha level was 5%. As many as 101 from 16 men (15.8%) and 85 women (84.2%) were obtained. Comorbid status (p-value = 0.001) and duration of treatment (p-value = 0.034 and 0.015) had a significant association with the occurrence of long-term COVID-19. Meanwhile, age, gender, occupation, type of care, and vaccination status were not likely associated with long-term COVID-19. COVID-19 patients with comorbidity and a long duration of treatment are more likely to experience long-term COVID-19. Keywords: COVID-19, long-term COVID-19, factor, public health
Primary Pulmonary Lymphoma with Superior Vena Cava Syndrome Alfian Nur Rosyid; Resti Yudhawati Meliana
Biomolecular and Health Science Journal Vol. 1 No. 2 (2018): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.449 KB) | DOI: 10.20473/bhsj.v1i2.9858

Abstract

Primary Pulmonary Lymphoma (PPL) is a clonal proliferation of lymphoid cells that involve one or two lungs (parenchyma and or bronchi. PPL is found in approximately 0.4% of all lymphoma cases and 3.6% of NHL cases. Five years survival rate at stage I and II is 90%, and 80% in stage III and IV. A 63-year-old male farmer presented with chief complaint of shortness of breath for one week before admission and preceded by coughing for a month, loss of appetite and night sweating. There was an abnormal physical examination on the right side of the chest with non-tender lymph node enlargements in the right supraclavicular and neck region and superior vena cava syndrome. CT guided FNAB suggesting NHL. Patient was treated with CHOP chemotherapy regiment. However, with high grade lymphoma, patient did not respond well.
The Role of Imaging In The Diagnosis of Pulmonary Embolism Alfian Nur Rosyid; M. Yamin; Arina Dery Puspitasari
Biomolecular and Health Science Journal Vol. 2 No. 1 (2019): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (319.3 KB) | DOI: 10.20473/bhsj.v2i1.13281

Abstract

Pulmonary embolism is a common condition and sometimes can be life-threatening. A proper diagnosis can reduce mortality. Some examinations are needed to diagnose pulmonary embolism, including assessing the risk factors, clinical examination, D-dimer tests, and imaging. Imaging is necessary when the previous assessment requires further investigation. There are more imaging that can be used to diagnose and assess the severity of pulmonary embolism. However, it is still controversial regarding imaging modalities for optimizing pulmonary embolism diagnose. Chest X-Ray cannot exclude pulmonary embolism, but it is needed to guide the next examinations and to find alternative diagnoses. Pulmonary Multi-Detector CT Angiography is the gold standard to diagnose pulmonary embolism.
Pengetahuan, Gangguan Psikologis, dan Burnout Dokter Umum di Era Pandemi Covid-19 Alfian Nur Rosyid; Arina Dery Puspitasari; Tamara Nur Budiarti; Izzatul Fitriyah; Anggraini Dwi Sensusiati; Muhammad Amin
Jurnal Pengabdian Pada Masyarakat Vol 6 No 3 (2021)
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30653/002.202163.838

Abstract

KNOWLEDGE, PSYCHOLOGICAL DISORDERS, AND BURNOUT OF GENERAL PRACTITIONERS IN THE COVID-19 PANDEMIC ERA. High demand in work during the Covid-19 pandemic will cause psychological problems for general practitioners. These psychological disorders can cause burnout. The incidence of burnout is exacerbated by the lack of knowledge of general practitioners about the current condition. This study aims to determine the level of knowledge, psychological disorders, and burnout of general practitioners during the Covid-19 pandemic. The research design using quasi-experimental with one group pre posttest design without a control group. The population in this study was all participants that join the online seminar. Samples taken were 111 respondents with the total sampling technique. The data collection technique was done by using a questionnaire. The data obtained were analyzed using the Wilcoxon test and Kendall's tau-c test. The difference test before and after being given the seminar material shows a p-value of 0.001. The statistical analysis of the relationship between knowledge and burnout shows a p-value of 0.048. The statistical analysis of the relationship between stress and burnout shows a p-value of 0.026. The statistical analysis of the relationship between anxiety and burnout shows a p-value of 0.001. The statistical analysis of the relationship between depression and burnout showed a p-value of 0.002. There are differences in the knowledge of respondents before and after being given the seminar material. There is an association between knowledge with burnout, stress with burnout, anxiety with burnout, and depression with burnout.
Appendicular Tuberculosis as Manifestation of Gastrointestinal Tuberculosis: A Case Report Yuliza Yuliza; Alfian Nur Rosyid; Wiwin Is Effendi; Prastuti Asta Wulaningrum; Herley Windo Setiawan
Jurnal Respirasi Vol. 7 No. 3 (2021): September 2021
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (344.745 KB) | DOI: 10.20473/jr.v7-I.3.2021.122-126

Abstract

Introduction: Gastrointestinal tuberculosis (GI TB) is quite rare with 3% incidence of all extrapulmonary involvement. Appendicular TB may occur in 0.1 - 3% of cases. Diagnosis is often difficult because the patient usually complains about chronic abdominal pain and fever. A definite diagnosis is based on histopathological examination of resected specimens from the appendectomy procedure.Case: We present a 37-year-old male patient admitted to the hospital with chronic abdominal pain, fever, nausea, and loss of body weight. The patient never had a persistent cough, hemoptysis, or night sweating. Physical examination showed pain and muscular rigidity in the right iliac area during palpation with Blumberg's sign and Rovsing's sign positive. Abdomen ultrasound imaging showed an appendicular abscess. The patient underwent appendectomy afterwards with histopathology result showing TB. The patient was treated with first category anti-tuberculosis drugs (ATD).Discussion: Diagnosis of appendicular TB is difficult due to unspecific clinical presentations. Appendicular TB patients often complain of signs and symptoms which are similar to acute appendicitis. These conditions can delay ATD treatment because the definitive diagnosis could be made after histopathological examination.Summary: Appendicular TB is a rare case of extrapulmonary TB. It can present as acute appendicitis. The definitive diagnosis is based on the histopathological examination. It is recommended to check the appendicectomy specimens histopathologically to exclude TB or other diseases. 
The Effectiveness of Pulmonary Rehabilitation on Pulmonary Function among Adults Patients of COVID-19 Survivors: A Systematic Review Hasanudin Hasanudin; Tintin Sukartini; Makhfudli Makhfudli; Alfian Nur Rosyid; Natalia Christin Tiara Revita; Handira Nadhifatul Aini
Jurnal Respirasi Vol. 8 No. 1 (2022): January 2022
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (387.042 KB) | DOI: 10.20473/jr.v8-I.1.2022.15-25

Abstract

Introduction: Corona Virus Infection Disease (COVID-19) refers to the infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Most of COVID-19 survivors have residual symptoms after being discharged from the hospital, it then leads to the decreased lung function and quality of life (QoL). Pulmonary rehabilitation is essential because it can reduce the impact of these sequelae. This study aimed to determine the effectiveness of pulmonary rehabilitation in improving lung function among adult patients of COVID-19 survivors.Methods: This study was conducted using 5 databases, namely: CINAHL, PubMed, SAGE, Science Direct, and Scopus from 1 April 2020 to 30 September 2021. The combination of keywords used was: "Pulmonary Rehabilitation", “Pulmonary Function", and "Post-COVID-19". In assessing the bias and methodological quality of the articles obtained, this study used the Joanna Briggs Institute (JBI) critical appraisal checklist tools.Results: From 678 articles, 11 research articles met the criteria. Pulmonary rehabilitation performed in post-COVID-19 patients included the provision of aerobic exercise, breathing exercises, strength training, balance exercises, relaxation, occupational therapy, psychological support, and nutrition consultation. Lung rehabilitation mainly was performed two sessions a week for 3-8 weeks with different proportions for each patient according to clinical conditions and  ability limits. Spirometry and the 6-minute walk test (6MWT) revealed that patients who completed the pulmonary rehabilitation program experienced improvements in their lung function.Conclusion: Comprehensive pulmonary rehabilitation programs under supervision and psychotherapists are the right choice in improving lung function among COVID-19 survivor adult patients.
Kidney-Pulmonary Crosstalk from Pathophysiological Perspective Sharifa Audi Salsabila; Alfian Nur Rosyid; Maulana Antiyan Empitu; Ika Nindya Kadariswantiningsih; Satriyo Dwi Suryantoro; Mutiara Rizki Haryati; Mochammad Thaha; Yusuke Suzuki
Jurnal Respirasi Vol. 8 No. 1 (2022): January 2022
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (382.477 KB) | DOI: 10.20473/jr.v8-I.1.2022.44-51

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Lungs and kidneys are distant organs which are functionally related in physiological and pathological contexts. Acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) are common complications in acute kidney injury (AKI) or acute-on-chronic kidney disease. On the other hand, there is a considerable risk of AKI in respiratory diseases such as ARDS and chronic obstructive pulmonary disease (COPD). From a pathophysiological point of view, the kidney-lung crosstalk involves interdependency in the regulation of fluid hemodynamic, acid-base and electrolyte balance, and carbon dioxide partial pressure. Aside from the closely related function, the crosstalk may also occur by non-classical mechanisms such as through activation of systemic inflammation, excessive cytokine release, and the formation of auto-antibody which targets both kidneys and lungs. This review discussed several disease mechanisms by which kidney and lungs affect each other or are simultaneously affected by pathological processes. Particularly, this review discussed some specific mechanisms in lungs and kidneys, such as how hypoxemia and hypercapnia induced by ARDS may reduce kidney function and how distance injury on kidney may affect the development of non-cardiogenic edema lungs.
Faal Paru Difusi : [Lung Diffusion: A Review] Alfian Nur Rosyid; Isnin Anang Marhana
Jurnal Respirasi Vol. 4 No. 2 (2018): Mei 2018
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (804.205 KB) | DOI: 10.20473/jr.v4-I.2.2018.61-70

Abstract

Diffusion capacity is useful for measuring ability of pulmonary microcirculation to transfer oxygen and carbon dioxide from alveoli to capillaries. Physiological examination of diffusion is a continuation of physiological examination of ventilation. Diffusion capacity is measured by DLCO (Diffusing capacity for Carbon Monoxide). Measurement of oxygen diffusion capacity directly is very difficult so that indirect methods are used using carbonmonoxide (DLCO). Diffusion capacity of oxygen is equivalent to DLCO multiplied by 1.23. Normal value of DLCO is 20-30 ml/minute mmHg. Some factors that affect DLCO are Hb levels, COHb in smokers, and alveolar volume. Some techniques for measuring DLCO include Steady-state, Three-equation Single-breath, Nitrogen Washout, and Intra-breath DLCO. This test is indicated in pulmonary parenchymal disease (pulmonary fibrosis, asbestosis, sarcoidosis, interstitial lung disease), cystic fibrosis, pulmonary hypertension, and pulmonary bleeding. DLCO is increased in asthma patients, obesity, polycythemia, intraalveolar bleeding, and right-left heart shunting. DLCO is decreased in emphysematous lung patients, pulmonary post resection, bronchial obstruction, multiple pulmonary embolism, anemia, idiopathic pulmonary fibrosis, asbestosis, sarcoidosis, vascular collagen disease, hypersensitive pneumonitis, and alveolar proteinosis.
Drug Utilization Study of Lopinavir And Ritonavir In Covid-19 Patients Aryani, Toetik; D. Puspitasari, Arina; Nafikhah, Wardah Zuhan; Rosyid, Alfian Nur; Astanti, Erika
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : CV. Ridwan Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (206.598 KB) | DOI: 10.36418/syntax-literate.v7i12.10447

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The world pandemic of COVID-19 which caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a very infectious and contagious. Lopinavir and ritonavir is recommended based on guidelines from National Health Commission of China as an antiviral therapy for COVID-19. Both lopinavir and ritonavir inhibit the 3CLpro enzyme’s action, which its role in replication also release of viruses. As protease inhibitor in Human Immunodeficiency Virus (HIV), both lopinavir and ritonavir’s target is a symmetrical bag of C2 where does not exist in 3CLpro enzyme of corona virus. This literature review is needed to determine the outcome of using lopinavir and ritonavir in order to find a conclusion that can be used as a basis for intervening drug administration in patients of COVID-19. A method of narrative review was used in this study which was carried out by searching on Pubmed and Science direct. After doing abstract screening and title based on the inclusion criteria, 13 articles were left to be analyzed. These articles were analyzed using predetermined clinical outcome parameters, namely duration of hospital stay, composite event, clinical symptom score, time to achieve negative RT-PCR, duration of mechanical ventilation, and all-cause mortality. Based on all reviewed articles, the majority of clinical outcome parameters showed that the outcome was no better than standard care or other drugs. From this review, it can be concluded that lopinavir along with ritonavir provide no better clinical outcomes than standard therapy or other drugs in COVID-19’s patients.
Integrated Care Plan In The Hospital Setting: A Scoping Review Bangun Mukti Ardi; Nursalam Nursalam; Alfian Nur Rosyid
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 7 No 2 (2023): Medical Technology and Public Health Journal September 2023
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mtphj.v7i2.4733

Abstract

Improving the quality of healthcare services in hospitals is one of the main goals of achieving a high-quality healthcare system. One of the efforts to enhance the quality of healthcare services in hospitals is implementing an integrated care plan. This study aims to determine the implementation of integrated care plans in hospitals. There were no limitations on methodologies, dates, or settings when reviewing papers describing qualitative or quantitative studies examining the implementation of integrated care plans in hospitals. The setting, design, and findings were all extracted from key study aspects. The major components of the integrated care plan's key components served as a framework for organizing the findings. There are 15 relevant papers published between 2018 and 2023. Most of the studies reported are qualitative, where healthcare workers reflect on their experiences and preferences regarding implementing an integrated care plan. These studies reported on issues underlying the need for the implementation of an integrated care plan, including poor administrative and management systems, lack of access, lack of coordination, lack of regulation, lack of knowledge, and lack of experience, with the ultimate goal of care being aware of cooperation and benefits for patients. An efficient way to raise patient satisfaction and improve the standard of healthcare services is to establish an Integrated Care Plan in hospitals. The efficacy and efficiency of patient care in hospitals can be improved by implementing a more structured and measurable care plan. Keywords: Integrated care plan, integrated health care systems, integrated delivery system, hospital.