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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Farmasi Klinik Indonesia Jurnal Penelitian Pendidikan IPA (JPPIPA) JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Farmagazine Jurnal Ilmiah Medicamento Poltekita: Jurnal Pengabdian Masyarakat Jurnal Pengabdian kepada Masyarakat Usadha
RR. Asih Juanita
Universitas Mahasaraswati Denpasar
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Edukasi Perilaku Hidup Sehat di Era Normal Baru Menggunakan Audiobook bagi Penyandang Disabilitas Sensorik Netra Dwi Arymbhi Sanjaya; Herleeyana Meriyani; RR. Asih Juanita; Nyoman Budiartha Siada
Poltekita: Jurnal Pengabdian Masyarakat Vol. 3 No. 4 (2022): Oktober - Desember
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (733.96 KB) | DOI: 10.33860/pjpm.v3i4.1136

Abstract

COVID-19 and changes in the health order in the new normal era have led to health problems, especially in blind people. Blind people have more difficulty accessing and getting health information. Good quality education and providing information with appropriate media are very important to improve a healthy lifestyle in the new normal era. Education and information about the healthy lifestyle in a new normal era with an audiobook aimed to improve knowledge about the healthy lifestyle in the new normal era at Dria-Raba Foundation. The method in this activity was to provide knowledge about the healthy lifestyle in new-normal using the audiobook to 23 blind people at Dria-Raba Foundation. A pre-test and post-test were analyzed using the Wilcoxon signed-rank test to evaluate the efficacy of the audiobook. The result showed a significant increase in knowledge from a score of 70 to 80 (p<0.05), thus education using the audiobook for blind people at the Dria-Raba Foundation to increase knowledge about a healthy lifestyle in new-normal. To improve the health quality of blind people, various types of audiobooks on health topics can be created. ABSTRAK Adanya pandemi Coronavirus Disease (COVID-19) dan perubahan tatanan kesehatan di era normal baru menyebabkan masalah terkait kesehatan yang dihadapi oleh penyandang disabilitas sensorik netra menjadi semakin kompleks. Penyandang disabilitas sensorik netra sulit untuk mendapatkan akses dan informasi tentang kesehatan. Dukungan berupa edukasi dan pemberian informasi dengan media yang sesuai menjadi sangat penting untuk memperbaiki perilaku hidup sehat di era normal baru. Pemberian edukasi terkait perilaku hidup sehat di era normal baru dengan menggunakan audiobook bertujuan untuk meningkatkan pengetahuan para penyandang disabilitas sensorik netra di Yayasan Dria-Raba tentang perilaku hidup sehat di era normal baru. Metode yang diterapkan dalam kegiatan pengabdian kepada masyarakat ini yaitu memberikan edukasi melalui audiobook kepada 23 orang penyandang disabilitas sensorik netra di Yayasan Dria-Raba. Untuk mengukur keberhasilan audiobook, dilakukan pre-test dan post-test yang kemudian dianalisis menggunakan uji Wilcoxon Signed-rank test. Hasil uji menunjukkan adanya peningkatan pengetahuan yang signifikan dari skor 70 menjadi 80 (p<0,05), sehingga dapat disimpulkan bahwa edukasi menggunakan audiobook bagi penyandang disabilitas sensorik netra di Yayasan Dria-Raba mampu meningkatkan pengetahuan para penyandang disabilitas sensorik netra tentang perilaku hidup sehat di era normal baru. Dalam hal meningkatkan kualitas kesehatan bagi para penyandang disabilitas sensorik netra, diharapkan dapat diciptakan berbagai audiobook dengan tema kesehatan lainnya.
Kajian Literatur: Study Design Dalam Farmakoepidemiologi Untuk Mengetahui Resistensi Bakteri Terhadap Antibiotik Herleeyana Meriyani; Dwi Arymbhi Sanjaya; Rr Asih Juanita; Nyoman Budiartha Siada
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 8, No 1 (2023)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v8i1.61651

Abstract

Penelitian terkait resistensi bakteri terhadap antibiotik dapat dilakukan dengan berbagai study design. Study design merupakan salah satu titik kritis dalam penelitian resistensi bakteri terhadap antibiotik. Penelitian ini bertujuan untuk memberikan gambaran kelebihan dan kekurangan dari study design yang digunakan dalam penelitian farmakoepidemiologi tentang resistensi bakteri terhadap antibiotik. Pencarian literatur dilakukan secara elektronik untuk artikel yang dipublikasikan tahun 2011 hingga 30 Juni 2021 pada basis data EBSCO, Plos One, Proquest, PubMed, ScienceDirect, dan Google Scholar. Kriteria inklusi meliputi original article dengan desain cohort (prospective dan retrospective), case control, cross-sectional dan ecological study; memiliki Digital Object Identifier (DOI); dipublikasi 10 tahun terakhir; serta mengunakan Bahasa Inggris. Artikel dalam bentuk review, tidak merupakan full text, dan artikel dengan jumlah sampel penelitian yang tidak jelas tidak disertakan dalam kajian ini. Artikel yang terkumpul dari 6 database sejumlah 209 artikel (EBSCO 45 artikel, Plos One 42 artikel, ProQuest 32 artikel, PubMed 68 artikel, ScienceDirect 19 artikel dan Google Scholar 3 artikel). Duplikasi artikel dieksklusi (29 artikel). Artikel tidak memenuhi kriteria inklusi (86 artikel), 64 artikel tidak relavan dengan tujuan penelitian, sehingga diperoleh 30 artikel dalam studi ini. Rancangan penelitian pada penelitian ini yaitu case-control (2 artikel), cohort-prospective (14 artikel), cohort-retrospective (5 artikel), cross-sectional (8 artikel) dan ecological study (1 artikel). Masing-masing rancangan memiliki kelebihan dan kekurangannya masing-masing. Pemilihan desain studi dalam penelitian resistensi bakteri terhadap antibiotik dilakukan sesuai dengan tujuan penelitian, jenis paparan yang diamati, jenis outcome serta tipe penelitian (comparative, correlative study) serta ketersediaan sumber daya dalam melakukan penelitian resistensi bakteri terhadap antibiotik.
Blush-On Compact Powder dengan Pewarna Alami dari Ekstrak Etanol Kulit Buah Naga (Hylocereus Lemairei) Ni Made Dharma Shantini Suena; Rr. Asih Juanita; Ni Putu Udayana Antari
Jurnal Penelitian Pendidikan IPA Vol 9 No 5 (2023): May
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i5.2445

Abstract

Cosmetics are one of the women's basic needs, but several cosmetic products on the market use synthetic dyes such as Rhodamine B, which cause various risks dangerous to health. Natural dyes are non-toxic, renewable, and environmentally friendly, one of which is anthocyanins found in dragon fruit peel. Blush-on is a cosmetic containing a dye that women often use. This study aimed to determine that the dragon fruit peel ethanolic extract can be used as a natural dye in blush-on compact powder preparations with good physical quality. Blush-on was made with various concentrations of dragon fruit peel ethanol extract of 20% (F1), 25% (F2), and 30% (F3). The preparations were observed for organoleptic and homogeneity, pH value, friability, and hedonic test during four weeks of storage, with descriptive data analysis. The results showed that dragon fruit peel extract blush-on did not meet some of the physical quality test requirements for blush-on. It is because the color of the blush-on should be red. However, the color of the preparation is white to brownish, and the preparation is also fragile. The preparation meets the requirements of homogeneity and pH value according to the physiological pH of the skin. It remains stable for four weeks of storage. F1 is the most preferred by panelists based on a preference test for the preparation's shape, color, and odor. Dragon fruit peel extract blush-on has not yet fulfilled its function as a decorative cosmetic to give color to the skin
Formulasi Dan Uji Mutu Fisik Sediaan Foot Lotion Ekstrak Etanol Daun Sirih (Piper bettle L.) Dengan Variasi Konsentrasi Asam Stearat Debby Juliadi; Rr Asih Juanita; Ni Putu Dewi Agustini
Usadha Vol 2 No 2 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i2.6420

Abstract

Betel leaf extract (Piper bettle L.) is known to contain flavonoid compounds that have antibacterial activity. Betel leaf extract needs to be formulated as a foot preparation lotion to increase the comfort of use as a topical antibacterial. The composition of the emulsifier influences the physical stability of the preparation foot lotion used. This study aims to determine the variation of stearic acid preparations foot lotion, which has good physical quality and is stable in storage. This research is purely experimental laboratory research that aims at development (development), namely developing something in an existing field (development of test methods, drug formulation). The observed responses were the physical quality of the preparations, which included organoleptic tests, homogeneity tests, pH tests, spreadability tests, and adhesion tests. The physical quality of preparations of foot lotion was analyzed descriptively. This research began with a maceration process using 70% ethanol to obtain a thick betel leaf extract (Piper bettle L.). This study made three preparation formulas with foot lotion with stearic acid concentrations of 10%, 12.5%, and 15%. The preparations that have been made are then tested for their physical quality and stability during four weeks of storage. The results of this study indicate that the preparations obtained foot lotion betel leaf ethanol extract (Piper bettle L.) with a variation of stearic acid of 10% to produce preparations of foot lotion with good physical quality seen from organoleptic tests, homogeneity, pH, spreadability, and adhesion and stable in storage for four weeks.
Tren Penggunaan Antibiotik dan Profil Resistensi pada Kelompok Critical-Priority Bacteria di ICU Rumah Sakit “X” Provinsi Bali (2017-2019) Dwi Arymbhi Sanjaya; Rr Asih Juanita; Herleeyana Meriyani; Nyoman Budiartha Siada; Komang Triani Lestari
JPSCR: Journal of Pharmaceutical Science and Clinical Research Articles In-Press
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v8i3.71717

Abstract

Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, dan Escherichia coli merupakan kelompok critical-priority bacteria yang telah mengalami multi drug resistant (MDR) dan sering ditemukan di Intensive Care Unit (ICU). Isolat bakteri-bakteri berjumlah lebih dari 75% mengalami MDR di ICU sebuah rumah sakit umum daerah di Bali, Indonesia. Penggunaan antibiotik yang tinggi berkaitan dengan tingkat resistensi bakteri terhadap antibiotik. Pola resistensi bakteri terhadap antibiotik dapat berbeda di setiap wilayah yang disebabkan oleh adanya perbedaan lingkungan dan perbedaan tingkat penggunaan antibiotik di wilayah tersebut. Penelitian ini bertujuan untuk mengetahui tren penggunaan antibiotik sistemik, pola resistensi dan hubungan antara tingkat penggunaan dengan persentase resistensi bakteri terhadap antibiotik pada kelompok critical-priority bacteria di ICU rumah sakit “X” provinsi Bali. Penelitian ini merupakan penelitian ekologikal yang menggunakan data sekunder selama tahun 2017-2019. Analisis tren penggunaan antibiotik dianalisis menggunakan time series analysis. Hubungan antara tingkat penggunaan antibiotik dan persentase resistensi bakteri prioritas kritis dianalisis dengan regresi linier. Hasil penelitian menunjukkan bahwa antibiotik gentamisin, amikasin, dan siprofloksasin mengalami peningkatan tren penggunaan sedangkan ampisilin, ampisilin-sulbaktam, seftazidim, dan meropenem mengalami penurunan tren penggunaan. Time series analysis menunjukkan penggunaan antibiotik yang fluktuatif. Selain itu, didapatkan bahwa A. baumannii masuk dalam dua kategori fenotipik CDC yaitu, carbNS_Acine dan MDR_Acine sedangkan K. pneumoniae masuk dalam kategori ESCklebsiella. Tingkat penggunaan antibiotik sistemik di ICU dengan persentase resistensi E. coli, K. pneumoniae, dan P. aeruginosa di ICU (p<0,05) terdapat hubungan signifikan, tetapi tidak terdapat hubungan yang signifikan antara penggunaan antibiotik sistemik pada pasien di ICU dengan persentase resistensi bakteri A. baumannii (p>0,05).
Antibiotic consumption and resistance: a 3-years ecological study for four critical groups of bacteria in a general regional hospital Dwi Arymbhi Sanjaya; Nyoman Budiartha Siada; Rr Asih Juanita; I Putu Yudistira Mahaputra; Made Gek Adisti Kamalia; Herleeyana Meriyani
Pharmaciana Vol 14, No 1 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i1.27321

Abstract

Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae are the most critical groups of multi-drug resistant (MDR) bacteria that cause a threat in hospitals. This study identified the trend of antibiotic consumption, antibiotic resistance pattern, and the relationship between antibiotic consumption and antibiotic resistance in a critical group of bacteria in a general regional hospital. This ecological study was based on retrospective data from inpatient databases in a general regional hospital over three years (2017-2019). The trend for annual antibiotic consumption over 2017-2019 was defined as defined daily doses/100 bed-days. The relationship between total antibiotic consumption and the percentage of antibiotic resistance among four isolated critical bacteria was explored in time series analysis and linear regression. The most frequently used antibiotic was ampicillin (220.33 DDD/100 bed-days), ciprofloxacin (126.86 DDD/100 bed-days), and ampicillin-sulbactam (126.34 DDD/100 bed-days). There was a significant relationship between antibiotic consumption (ampicillin, ampicillin-sulbactam, ceftazidime, gentamicin, amikacin, and ciprofloxacin) in DDD/100 bed-days and antibiotic resistance in E. coli, K. pneumoniae, and P. aeruginosa (p<0.05) but not statically significant in A. baumannii (p=0.062). The annual usage fluctuated or remained stable, with no statistically significant trends change. The relationship between antibiotic consumption and antibiotic resistance was significant in three out of four critical groups of bacteria.
Co-Authors Debby Juliadi Dwi A. Sanjaya Dwi Arymbhi Sanjaya Dwi Arymbhi Sanjaya Dwi Arymbhi Sanjaya Herleeyana Meriyani Herleeyana Meriyani Herleeyana Meriyani I Gede Made Suradnyana I Putu Yudistira Mahaputra Komang Triani Lestari Made Gek Adisti Kamalia Ni Putu Dewi Agustini Ni Putu Udayana Antari Ni Wayan Sutariani Nyoman B. Siada Nyoman Budiartha Siada Nyoman Budiartha Siada Nyoman Budiartha Siada Putu Sukma Purnamasari Suena, Ni Made Dharma Shantini Suradnyana, I Gede Made Triska Ananda Rahayu