Garuda - Garba Rujukan Digital

Effect Of Bangun-Bangun Leaves Ethanol Extract On Lipid Profile Ovariectomized Female Rats Suharyanisa; Hasibuan, Poppy Anjelisa Zaitun; Nasution, Pandapotan
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 4 No. 1 (2021): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v4i1.5360

Menopause was a condition of the body when ovaries stopped producing ovum; ovum is the main producer of estrogen hormone. Menopause can increasing lipid profile in blood; it causes any problems in the cardiovascular system. People of North Sumatra have long used Bangun-Bangun leaves as a breastfeeding agent; it contains flavonoid bioactive compounds, which are be expected to replace lost estrogen hormone. This study determined the estrogenic activity of Bangun-Bangun leaves ethanol extract (BBLEE) on lipid levels of ovariectomized female rats as a menopausal model. BBLEE has obtained by maceration techniques with 96% ethanol and extract used on 24 ovariectomized rats which were divided into 6 groups. Group 1 (normal), group 2 (positive) was treated by estradiol at dose of 0.18 mg/kg BW, group 3 (negative) was treated by 0.5% Na-CMC and group 4, 5, 6 were treated by BBLEE at dose of 30, 60, 90 mg/kg BW given orally for 14 days. The data were analyzed by ANOVA and Post Hoc Tukey HSD test. The result showed that effective dose of BBLEE was 90 mg/kg BW which improved lipid profile (TC = 55.75Â±0.47; TG = 63.00Â±0.40; HDL = 37.00Â±0.81; LDL = 30.50Â±0.86) in blood of ovariectomized female rats as a menopausal model. BBLEE at the dose of 90 mg/kg BW can ameliorate the lipid profile in the blood of ovariectomized female rats as a menopausal model.

PEMBUATAN PATI DARI RIMPANG LENGKUAS, TEMULAWAK, TEMUKUNCI SERTA KARAKTERISASINYA Pandapotan Nasution; Suharyanisa Suharyanisa; Manahan Situmorang; Nurpita Putri Manihuruk
Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

The rhizome is part of the plant for food reserves, including storing carbohydrates (starch), therefore rhizomes of Galangal, Curcuma, Fingerroot rhizome can be used as a source of starch. This study used an exploratory method which included isolation of starch from Galangal, Curcuma, Fingerroot Rhizome, macroscopic examination, microscopic examination, sample collection, sample processing, and examination of the characterization of starch. The results of starch characterization obtained yields for Galangal starch 2.6%, Curcuma starch 5.4%, Fingerroot rhizome starch 4.1%; determination of total ash content for Galangal starch 1.4%; Curcuma starch 2.0%, Fingerroot rhizome starch 1.0%; determination of drying shrinkage for 1.8% Galangal starch, 2.4% Curcuma starch, 3.2% Fingerroot rhizome starch; determination of acid-insoluble ash content for 0.6% Galangal starch, 0.7% Curcuma starch, 0.7%Fingerroot rhizome starch.

KARAKTERISASI DAN SKRINING FITOKIMIA SERTA ANALISIS FLAVONOID DARI BUAH MENGKUDU (Morindacitrifolia L) SECARA KROMATOGRAFI LAPIS TIPIS Panal Sitorus; Suharyanisa Suharyanisa; Devina Chandra; Berton Sitanggang
Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Noni fruit (Morindacitrifolia L.) is a medicinal plant that is well known by the people in Indonesia. Noni is efficacious as an immune enhancer, normalizes blood pressure, anti-cancer, analgesic, diabetes mellitus, heart disease, stroke, antimicrobial. To know the characteristics of simplicia and the class of compounds from the noni fruit as well as to analyze the flavonoid compounds contained in the noni fruit using the thin layer chromatography method. The flavonoid compounds were extracted by maceration using ethanol solvent and then the ethanol extract was tested by thin-layer chromatography using 1% HCl mobile phase and spotting with 1 N H2SO4 reagent and methanol pa (1: 1% v/v). Result of simplicia characterization of fruit Noni, obtained 1.32% water content, 38.41 % water soluble extract content, 16.7% ethanol soluble extract content, 6.09% total ash content, and 0.45 acid insoluble ash content. %. Noni fruit simplicia contains chemical compounds of alkaloids, tannins, flavonoids, triterpenoids/steroids, anthraquinones, saponins with phytochemical screening tests. The value of Rf from the analysis of noni fruit flavonoid compounds using the Thin Layer Chromatography method with 3 repetitions is 0.75; 0.68 and 0.62. This indicates the presence of flavonoid compounds in the noni fruit.

UJI AKTIVITAS ANTIBAKTERI DARI BLACK GARLIC DENGAN VARIASI WAKTU BERBEDA TERHADAP Streptococcusmutans PENYEBAB KARIES GIGI Vivi Purwandari; Jon Kenedy Marpaung; Suharyanisa Suharyanisa
Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Dental cariesand gingivitis are the two mostcommon dental and oral diseases in human society. The main cause of both diseasesis a collection of bacteria bound in anorganicmatrix and firmlyattachedtothe tooth surface known as plaque. Black garlicis garlic that has been processed by fermentationat a certaintemperaturefor a long time, resulting in new compounds that have pharmacological effects showing broad antibiotic properties against gram-positiveand gram-negative bacteria, includingstrains that are multi-bacterial. Antibiotic resistance. The purpose of this study was to determine the antibacterial activity of black garlic against Streptococcus mutans bacteria and to determine the differences in the variation of the antibacterial fermentation time of blackgarlicon the antibacterial activity of Streptococcus mutans bacteria. The methodused in this study isanexperimentalmethod (experimentalresearch) to determine the effect of blackgarlic as anantibacterial against Streptococcusmutans. The resultsobtained fromthis study are blackgarlic extract containsalkal oids, flavonoids, tannins, andsaponins. Black garlic extract from variations of 7 days, 12 days, 15 days, and Chlorhexidine had an inhibitoryzone with a strong category while steriledistilled water had an inhibitionzone in the weakcategory.

SOSIALISASI PENANAMAN POHON MATOA ALIRAN SUNGAI DI DESA GARUNGGANG KECAMATAN KUALA KABUPATEN LANGKAT Cut Masyitah Thaib; Monica Suryani; Suharyanisa
JURNAL PENGABDIAN KEPADA MASYARAKAT SISTHANA Vol. 4 No. 1 (2022): Juni : Jurnal Pengabdian Kepada Masyarakat Sisthana
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/pkmsisthana.v4i1.95

Bencana alam tanah longsor maupun banjir sering terjadi di Desa Garunggang Kecamatan Kuala Kabupaten Langkat, Sumatera Utara. Banjir merupakan peristiwa dimana daratan yang biasanya kering (bukan daerah rawa) menjadi tergenang oleh air, hal ini disebabkan oleh curah hujan yang tinggi dan kondisi topografii wilayah berupa daratan rendah hingga cekung. Untuk mencegah terjadinya banjir dan tanah longsor dilakukan penanaman pohon matoa (Pometia pinnata) di daerah aliran sungai desa Garunggang Kecamatan Kuala Kabupaten Langkat. Kegiatan ini dibuka oleh Pembawa acara, setelah itu Menyanyikan Lagu Indonesia Raya, Kata kata sambutan, Penandatanganan Kerjasama dan dilanjutkan dengan penanaman pohon serta foto bersama. Kegiatan sosialisasi penanaman pohon matoa (Pometia pinnata) di daerah aliran sungai desa Garunggang Kecamatan Kuala Kabupaten Langkat. Kegiatan ini disambut baik oleh masyarakat penanaman pohon matoa (Pometia pinnata) di daerah aliran sungai desa Garunggang Kecamatan Kuala Kabupaten Langkat. Maka dapat disimpulkan bahwa kegiatan ini membawa dampak dan pengaruh yang baik terhadap pengetahuan masyarakat dalam melestarikan lingkungan alam di kawasan Hulu DAS Wampu Desa Garunggang. Marilah kita jaga lingkungan kita bersama sama, semoga dimasa yang akan datang, kegiatan ini dapat lebih bermanfaat untuk sekitarnya.

PEMBUATAN PATI DARI RIMPANG LENGKUAS, TEMULAWAK, TEMUKUNCI SERTA KARAKTERISASINYA Pandapotan Nasution; Suharyanisa Suharyanisa; Manahan Situmorang; Nurpita Putri Manihuruk
Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i2.2791

The rhizome is part of the plant for food reserves, including storing carbohydrates (starch), therefore rhizomes of Galangal, Curcuma, Fingerroot rhizome can be used as a source of starch. This study used an exploratory method which included isolation of starch from Galangal, Curcuma, Fingerroot Rhizome, macroscopic examination, microscopic examination, sample collection, sample processing, and examination of the characterization of starch. The results of starch characterization obtained yields for Galangal starch 2.6%, Curcuma starch 5.4%, Fingerroot rhizome starch 4.1%; determination of total ash content for Galangal starch 1.4%; Curcuma starch 2.0%, Fingerroot rhizome starch 1.0%; determination of drying shrinkage for 1.8% Galangal starch, 2.4% Curcuma starch, 3.2% Fingerroot rhizome starch; determination of acid-insoluble ash content for 0.6% Galangal starch, 0.7% Curcuma starch, 0.7%Fingerroot rhizome starch.

KARAKTERISASI DAN SKRINING FITOKIMIA SERTA ANALISIS FLAVONOID DARI BUAH MENGKUDU (Morindacitrifolia L) SECARA KROMATOGRAFI LAPIS TIPIS Panal Sitorus; Suharyanisa Suharyanisa; Devina Chandra; Siti Nurbaya; Berton Sitanggang
Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i2.2793

Noni fruit (Morindacitrifolia L.) is a medicinal plant that is well known by the people in Indonesia. Noni is efficacious as an immune enhancer, normalizes blood pressure, anti-cancer, analgesic, diabetes mellitus, heart disease, stroke, antimicrobial. To know the characteristics of simplicia and the class of compounds from the noni fruit as well as to analyze the flavonoid compounds contained in the noni fruit using the thin layer chromatography method. The flavonoid compounds were extracted by maceration using ethanol solvent and then the ethanol extract was tested by thin-layer chromatography using 1% HCl mobile phase and spotting with 1 N H2SO4 reagent and methanol pa (1: 1% v/v). Result of simplicia characterization of fruit Noni, obtained 1.32% water content, 38.41 % water soluble extract content, 16.7% ethanol soluble extract content, 6.09% total ash content, and 0.45 acid insoluble ash content. %. Noni fruit simplicia contains chemical compounds of alkaloids, tannins, flavonoids, triterpenoids/steroids, anthraquinones, saponins with phytochemical screening tests. The value of Rf from the analysis of noni fruit flavonoid compounds using the Thin Layer Chromatography method with 3 repetitions is 0.75; 0.68 and 0.62. This indicates the presence of flavonoid compounds in the noni fruit.

UJI AKTIVITAS ANTIBAKTERI DARI BLACK GARLIC DENGAN VARIASI WAKTU BERBEDA TERHADAP Streptococcusmutans PENYEBAB KARIES GIGI Vivi Purwandari; Jon Kenedy Marpaung; Suharyanisa Suharyanisa
Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i2.2797

Dental cariesand gingivitis are the two mostcommon dental and oral diseases in human society. The main cause of both diseasesis a collection of bacteria bound in anorganicmatrix and firmlyattachedtothe tooth surface known as plaque. Black garlicis garlic that has been processed by fermentationat a certaintemperaturefor a long time, resulting in new compounds that have pharmacological effects showing broad antibiotic properties against gram-positiveand gram-negative bacteria, includingstrains that are multi-bacterial. Antibiotic resistance. The purpose of this study was to determine the antibacterial activity of black garlic against Streptococcus mutans bacteria and to determine the differences in the variation of the antibacterial fermentation time of blackgarlicon the antibacterial activity of Streptococcus mutans bacteria. The methodused in this study isanexperimentalmethod (experimentalresearch) to determine the effect of blackgarlic as anantibacterial against Streptococcusmutans. The resultsobtained fromthis study are blackgarlic extract containsalkal oids, flavonoids, tannins, andsaponins. Black garlic extract from variations of 7 days, 12 days, 15 days, and Chlorhexidine had an inhibitoryzone with a strong category while steriledistilled water had an inhibitionzone in the weakcategory.

UJI AKTIVITAS ANTIBAKTERI EKSTRAK BUNGA KECOMBRANG (Etlingera elatior) TERHADAP PERTUMBUHAN BAKTERI Salmonella thypi Pandapotan Nasution; Jon Kenedy Marpaung; Suharyanisa Suharyanisa; Rolastri Sitanggang
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Kecombrang (Etlingera elatior) is a type of spice that has long been known and used by humans as medicine. Kecombrang flower parts contain several chemical compounds, namely: alkaloids, flavonoids, and saponins. In addition, kecombrang flowers can also inhibit the growth of Salmonella typhi bacteria. This study aims to determine the concentration of ethanolic extract of kecombrang flower (Etlingera elatior) which is effective in inhibiting the growth of Salmonella typhi bacteria. The research sample was Kecombrang Flowers purchased at the Tarutung traditional market. This research was carried out experimentally including sampling, drying simplicia, maceration using 70% ethanol solvent, making extracts made using a rotary evaporator, and testing the antibacterial activity of kecombrang flowers using the disc diffusion method. Data analysis was conducted to see the effect of kecombrang flower ethanol extract on the activity of Salmonella typhi bacteria. The results of the study found that the results of phytochemical screening showed simplicia and ethanol extract of kecombrang flower leaves contained alkaloids, flavonoids, and saponins. While the results of the antibacterial activity test of the ethanolic extract of kecombrang flower leaves have antibacterial properties against Salmonella typhi at extract concentrations of 45%, 50%, 55%, and 60% with inhibition zone diameters of 9.4 mm, 12.2 mm, 14.8 mm, respectively. , 16.3mm. The most effective concentration of ethanol extract to inhibit the growth of Salmonella typhi was at a concentration of 60% with a larger inhibition zone diameter of 16.3 mm.

SOSIALISASI PENANAMAN POHON MATOA ALIRAN SUNGAI DI DESA GARUNGGANG KECAMATAN KUALA KABUPATEN LANGKAT Cut Masyitah Thaib; Monica Suryani; Suharyanisa
JURNAL PENGABDIAN KEPADA MASYARAKAT SISTHANA Vol. 4 No. 1 (2022): Juni : Jurnal Pengabdian Kepada Masyarakat Sisthana
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/pkmsisthana.v4i1.95

Bencana alam tanah longsor maupun banjir sering terjadi di Desa Garunggang Kecamatan Kuala Kabupaten Langkat, Sumatera Utara. Banjir merupakan peristiwa dimana daratan yang biasanya kering (bukan daerah rawa) menjadi tergenang oleh air, hal ini disebabkan oleh curah hujan yang tinggi dan kondisi topografii wilayah berupa daratan rendah hingga cekung. Untuk mencegah terjadinya banjir dan tanah longsor dilakukan penanaman pohon matoa (Pometia pinnata) di daerah aliran sungai desa Garunggang Kecamatan Kuala Kabupaten Langkat. Kegiatan ini dibuka oleh Pembawa acara, setelah itu Menyanyikan Lagu Indonesia Raya, Kata kata sambutan, Penandatanganan Kerjasama dan dilanjutkan dengan penanaman pohon serta foto bersama. Kegiatan sosialisasi penanaman pohon matoa (Pometia pinnata) di daerah aliran sungai desa Garunggang Kecamatan Kuala Kabupaten Langkat. Kegiatan ini disambut baik oleh masyarakat penanaman pohon matoa (Pometia pinnata) di daerah aliran sungai desa Garunggang Kecamatan Kuala Kabupaten Langkat. Maka dapat disimpulkan bahwa kegiatan ini membawa dampak dan pengaruh yang baik terhadap pengetahuan masyarakat dalam melestarikan lingkungan alam di kawasan Hulu DAS Wampu Desa Garunggang. Marilah kita jaga lingkungan kita bersama sama, semoga dimasa yang akan datang, kegiatan ini dapat lebih bermanfaat untuk sekitarnya.

Title

Found 10 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 10 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 10 Documents
Search