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Siti Nurbaya

Program Studi D3 ANAFARMA, Universitas Sari Mutiara Indonesia

Author-ID : 3483787

Medicine & Pharmacology

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PENGGUNAAN KULIT BATANG JAMBLANG (Syzygiumcumini) DALAM FORMULASI PEWARNA RAMBUT Artha Yuliana Sianipar; Siti Nurbaya; Sisca Mayryanisa
Jurnal Farmanesia Vol 4 No 1 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Hair dye is a cosmetic used in hair makeup to color hair, either to restore the original hair color or change the original hair color to a new color. Jamblang bark contains dyes and produces tannins which are used to dye textiles. The purpose of this study was to determine that Jamblang bark extract could be formulated as a hair dye. Hair dye preparations contain Jamblang bark extract with concentrations of A (2.5%), B (5%), C (7.5%), and D (10%). Observation of color stability was carried out by means of a stability test against 15 washes and exposure in the sun for 5 hours on colored hair, then an irritation test was carried out. This study shows that a formula made with Jamblang bark extract can give hair a brown color. The longer the immersion of gray hair in hair dye preparations, the darker the resulting brown color at a concentration of C (7.5%). The results of stability tests against washing and sunlight showed that there was no change in hair color and did not cause skin irritation. Jamblang bark extract can be formulated as hair dye. The best dye was obtained from Formula C which consisted of 7.5% Jamblang stem bark extract producing a dark brown color.

SKRINING FITOKIMIA DAN UJI AKTIVITAS ANALGETIK EKSTRAK ETANOL JAHE MERAH (Zingiber officinale Rosc. Var Rubrum) DAN EKSTRAK ETANOL JAHE PUTIH (Zingiber officinale Rosc. Var Officinarum) PADA MENCIT PUTIH JANTAN Siti Nurbaya; Yosy Cinthya Eriwaty Silalahi; Trionaldo Putra
Jurnal Farmanesia Vol 4 No 1 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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One of the medicinal plants is ginger. The ginger plant has properties in overcoming pain, but it is not yet known how big the percentage of the strength of the analgesic activity of the ginger plant is. The components consisting of oleoresin are a complete picture of the content of ginger, namely essential oils and fixed oils consisting of gingerol, shagaol, and resin. Mice were divided into eight treatment groups (CMC 0.5%, Acetosal, EEJM (Red Ginger Ethanol Extract) 100, EEJM 200, EEJP (White Ginger Ethanol Extract) 100, EEJP 200, Combination 100, Combination 200). orally. Animals were induced with 3% acetic acid. Pain is characterized by the emergence of stretching which is indicated by the abdomen touching the base of the footing and both pairs of legs being pulled back. Observe stretching at intervals of every 10 minutes for 90 minutes. The characterization of red ginger rhizome simplicia and white ginger rhizome has met the requirements set by the Indonesian Herbal Pharmacopoeia. The results of phytochemical screening showed that simplicia and extracts from red and white ginger rhizome contained alkaloids and triterpenoids/steroids. The results showed that all treatment groups had an analgesic effect, which was not significantly different from the acetosal treatment (P>0.01). The highest analgesic power and effectiveness was seen in the EEJM 200mg/kg BW treatment group.

PENETAPAN KADAR FLAVONOID TOTAL DARI EKSTRAK ETANOL DAUN ANDALIMAN (Zanthoxylum acanthopodium DC.) Cut Masyithah Thaib; Siti Nurbaya; Martha Uli Oktavrina Rajagukguk
Jurnal Farmanesia Vol 4 No 1 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Flavonoids are a class of polyphenolic compounds that have an antioxidant effect by donating hydrogen atoms and linking them with metal ions. Most flavonoids are found in plants. One of the plants that contain lots of flavonoids is andaliman (Zanthoxylum acanthopodium DC). The purpose of this study was to determine the compounds contained in the Andaliman leaf and to determine the total flavonoid content of the Andaliman leaf extract. The type of research conducted was descriptive, including identification of plant material, collection of plant material, phytochemical screening, and examination of total flavonoids with visible ultraviolet spectrophotometry. Samples were taken from LobuSiregar village, Siborong-Borong, North Tapanuli. Andaliman leaf extract (Zanthoxylum acanthopodium DC) was obtained by the maceration method using 96% ethanol. Determination of total flavonoid content was carried out by the colorimetric method. The results of phytochemical screening showed the presence of alkaloids, flavonoids, tannins, and steroids. Determination of total flavonoid content calculated as quercetin with the regression equation y= 0.03278 X + 0.04086, and r = 0.99825. The measurement results of the total flavonoid content of the ethanol extract of Andaliman leaves were 39.65 ± 0.08 mg QE/g.

PENGARUH INFUSA KULIT BUAH MANGGIS (Garcinia mangostana) TERHADAP PROFIL FARMAKOKINETIKA PARASETAMOL PADA TIKUS PUTIH JANTAN (Rattus norvegicus L.) Kesaktian Manurung; Siti Nurbaya; Rezkita Raysyah
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Mangosteen rind is traditionally used by residents of Southeast Asia, especially Indonesia, to treat various diseases. Drug interactions can reduce or eliminate efficacy and cause serious health problems or problems. This study aims to determine the effect of mangosteen rind infusion on the pharmacokinetic profile of paracetamol administered orally to male white rats. Infusion of mangosteen rind was made in doses of 10% and 20%. The study was conducted by giving the solution successively for 7 days and on the 7th day after 4 hours, paracetamol solution was given orally. Furthermore, the blood of each male rat was taken with a time of 0 minutes, 10 minutes, 20 minutes, 30 minutes, 40 minutes, 60 minutes, 90 minutes, 120 minutes, 180 minutes, 240 minutes, 300 minutes, and 360 minutes and measured by UV spectrophotometry. a wavelength of 257 nm. The results showed that there was an effect of mangosteen rind infusion on paracetamol in test animals.

PENETAPAN KADAR KALSIUM PADA BEDAK TABUR DARI BAHAN BAKU CANGKANG KERANG BULU (Anadaraantiquata) SECARA KOMPLEKSOMETRI Siti Nurbaya; Artha Yuliana Sianipar; Elly Nurita Sitorus; Winton F. Situmorang
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Until now, the utilization of clamshell waste has been limited to handicraft materials, whereas shellfish waste has a high calcium carbonate composition of about 98% which can be used as a source of calcium in the synthesis of compounds containing calcium metal. The purpose of this study was to determine the level of calcium contained in the shells of mussels and to determine the levels of calcium in the preparation of talcum powder which was added with powdered shells of feathers as an abrasive. Complexometric titration is also used to determine calcium levels in powder preparations formulated with feather shells powder. The results showed that the shells of feather shells contained calcium levels of 19.49% while the loose powder preparations contained calcium levels of 1.475%. The test results of the research on the formulation of loose powder preparations met the physical evaluation requirements. The pH test on loose powder, namely pH 7, meets the requirements of SNI 16-4399-1996, the pH value of cream cosmetic products is required to range from 4.5 to 8.0. The fine degree test is qualified because the loose powder can pass the sieving using a 100 mesh.

PENETAPAN KADAR VITAMIN C PADA DAUN JELATANG (Urtica dioica L.) DENGAN MENGGUNAKAN SPEKTROFOTOMETRI ULTRAVIOLET Zuhairiah Nasution; Siti Nurbaya; Supartiningsih Supartiningsih; Tiurma Sitompul
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Nettle leaf (Urtica dioica L) is the most widely known species in the genus Urtica and has many benefits for the community, one of which is to treat venereal diseases, kidney disorders, allergies, diabetes, anemia, and digestive tract diseases. Vitamins contained in nettle leaves that are useful for the body is vitamin C. Vitamin C has properties that are easily damaged by heat, and easily soluble in water. This study aims to determine the levels of vitamin C in young and old nettle leaves by an ultraviolet spectrophotometric method using Aquadest solvent and read a wavelength of 265 nm with a linear regression equation y= ax + b with a value of y= 0.0525 + 0.0618 with r = 0.9878 each treatment was replicated 6 times. Based on the results of the qualitative test experiment, it was stated that in nettle leaves there was vitamin C with iodine solution reagent, FeCl3, Fehling A&B, and obtained vitamin C levels in old nettle leaves 0.2526 mg/g and in young nettle leaves 0.2026 mg/g. So that the levels of vitamin C in old nettle leaves are higher than in young nettle leaves.

UJI AKTIVITAS GETAH GAMBIR(Uncariagambir Roxb.) TERHADAP BAKTERI Escherichia coli DAN Salmonella typhi Adiansyah Adiansyah; Ahmad Gazali Sofwan; Siti Nurbaya; Lestari Simanjuntak
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Gambir is an extract of the leaf sap and twigs of the Gambir plant (Uncariagambir Roxb.) which has been dried. According to information, Gambir sap can be used as a mixture of drugs for burns, headache medicine, diarrhea medicine, mouthwash, thrush medicine. Because there is the main content of catechins and tannins. The purpose of this study was to determine the antibacterial activity of secondary metabolites and the concentration of Gambir sap (Uncariagambir Roxb.) against Escherichia coli and Salmonella typhi bacteria. The method used is agar diffusion using disc paper. The results showed that the diameter of the inhibition of Gambir sap on Escherichia coli bacteria at a concentration of 300 mg/ml in the bacterial test was 16.03 mm, at a concentration of 200 mg/ml there was a bacterial test of 15.00 mm and Salmonella typhi at a concentration of 300 mg/ml contained bacterial test 16.06 mm, at a concentration of 200 mg/ml bacterial test 16.03 mm.

ANALISA KADAR CEMARAN LOGAM MERKURI PADA IKAN SARDEN (Sardinella lemuru) KEMASAN KALENG SECARA SPEKTROFOTOMETRI SERAPAN ATOM (SSA) Yosy Cinthya Eriwaty Silalahi; Cut Masyithah Thaib; Siti Nurbaya
Jurnal Farmanesia Vol 4 No 2 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Food packaging in cans is a food preservation technology using high-temperature sterilization. Mercury is a heavy metal that can have a toxic effect on the body so it can cause death. This study aims to determine the levels of mercury contamination in canned sardines. The samples used in this study were 6 different brands of canned sardines. The method used to determine mercury (Hg) levels is qualitatively using color reagents and quantitatively using AAS (Atomic Absorption Spectrophotometry). The results obtained from 6 samples of canned sardines that were positive for heavy metal mercury (Hg) were indicated by the formation of orange color with KI reagent, yellow precipitate with NaOH, white precipitate with HCl. The wavelength used is 253.7 nm. The results showed that Brand A mercury 4.9814 ± 0.0301 mg/kg, Brand B 0.8757 ± 0.0308 mg/kg, Brand C 1.4899 ± 0 mg/kg, Brand D 1.4175 ± 0 mg/kg , Brand E 0.7527 ± 0 mg/kg, and Brand F 0.5270 ± 0 mg/kg. This study concludes that the mercury content in canned fish circulating in the Medan Brastagi Supermarket is above the maximum limit allowed by the National Standardization Agency (2016) in SNI 8222-2016, which is 0.5 mg/kg.

PENENTUAN KADAR VITAMIN C PADA JERUK MANIS (Citrussinensis) MENGGUNAKAN METODE TITRASI TITRASI NA-2,6 DICHLOROPHENOL INDOPHENOL DAN SPEKTROFOTOMETRI Siti Nurbaya; Muhammad Taufik; Artha Yuliana Sianipar; Zulfan Zulfan
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Vitamin C is one of the vitamins that is needed by humans and also one of the water-soluble vitamins, Vitamin C plays a role in the formation of intercellular collagen. For the solubility of vitamins B1, B2, B3, B5, B6, B7, B9, B12, and C are included in the types of water-soluble vitamins, and for the solubility vitamins A, D, E, and K are included in the types of soluble vitamins in fat. Vitamin C functions as an antioxidant and counteracts free radicals that can damage cells. Sources of vitamins are fresh fruits and vegetables. Sweet orange fruit contains vitamin C which is quite high. This study aims to determine and compare the results of vitamin C levels in sweet oranges using the Na 2,6 Dichlorophenol Indophenol titration method and spectrophotometry. The content of vitamin C using Na 2.6 Dichlorophenol Indophenol titration is 0.042%, while the content of vitamin C in sweet oranges using the UV-Vis spectrophotometry method produces levels of 0.351%. These results, shows that the levels of vitamin C obtained by using the UV-Vis spectrophotometry method are higher than those obtained by the iodometric method.

ANALISIS KADAR KALSIUM DAN BESI PADA DAUN TANAMAN BAYAM MERAH (Alternantheraamoena Voss) DAN DAUN TANAMAN BAYAM KAKAP (Amaranthus hybridus L) SECARA SPEKTROFOTOMETRI SERAPAN ATOM Ahmad Gazali Sofwan; Siti Nurbaya; Adiansyah Adiansyah; Pontisari Sitanggang
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Spinach (Amaranthus spp) is a leaf vegetable plant that is highly nutritious and favored by all levels of society. According to information, spinach plants can be used as an additional intake in the prevention of osteoporosis (bone loss) and anemia (lack of blood) because of the high calcium and iron content in them. Two types of spinach are known in the community, namely red spinach (Alternanthera amoena Voss) and spinach snapper (Amaranthus hybridus L). The purpose of this study was to determine the levels of calcium and iron in red spinach and snapper spinach leaves. The assay was carried out using an atomic absorption spectrophotometer with an air-acetylene flame. Quantitative analyzes were carried out at wavelengths of 422.7 nm for calcium and 248.3 nm for iron. The results showed that the levels of calcium and iron obtained with the levels of calcium and iron listed in the literature were different. The results also showed that there were differences in calcium and iron levels between red spinach and snapper spinach. Calcium levels in red spinach and snapper spinach leaves were 26.8016 mg/100g and 24.2759 mg/100g, respectively. The levels of iron in red spinach and snapper spinach leaves were 714.2621 mg/100g and 236.5369 mg/100g, respectively.

Co-Authors Adiansyah Adiansyah Agusmal Dalimunthe Ahmad Gazali Safwan Ahmad Gazali Sofwan Ahmad Hafizullah Ritonga Alan Maulana Amaliah Insani Aprili Yanti Simatupang Berton Sitanggang Cut Masyithah Thaib Devina Chandra Dicky Yuswardi Wiratma Elly Nurita Sitorus Elly Sitorus Eva Priasanti Sitanggang Fitri Margaretta Simarmata Fitri, Raissa Ika Kristina Julianto Irawan Karnerius Harefa Kesaktian Manurung Lestari Simanjuntak Manahan Situmorang Maringan Silitonga Martha Uli Oktavrina Rajagukguk Muhammad Taufik Natanael Priltuis Nina Paramita Nurussakinah Nurussakinah Panal Sitorus Pitalokasari br Ginting Pontisari Sitanggang Rezkita Raysyah Risda Hernidawati Nainggolan Sianipar, Artha Yuliana Sisca Mayryanisa Siti Maimunah Suharyanisa Supartiningsih Supartiningsih Tiurma Sitompul Trionaldo Purba Trionaldo Putra Vivi Purwandari Winton F. Situmorang Yettri Simarmata Yettrie Simarmata Yosy Cinthya Eriwaty Silalahi Yosy Cinthya Eriwaty Silalahi Zuhairiah Nasution Zuhairiah Zuhairiah Zuhairiah Zuhairiah Zulfan Zulfan

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