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All Journal Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) JSFK (Jurnal Sains Farmasi & Klinis) Majalah Farmasetika Jurnal Ilmiah Farmasi Farmasyifa Journal of Pharmaceutical and Health Research Jurnal Riset Farmasi Bandung Conference Series: Pharmacy
Livia Syafnir
Farmasi, Universitas Islam Bandung
Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : Bandung Conference Series: Pharmacy

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Penelusuran Pustaka Potensi Sayuran dari Genus Brassica sebagai Antibakteri Miaranti Tia Azhariani; Kiki Mulkiya Yuliawati; Livia Syafnir
Bandung Conference Series: Pharmacy Vol. 2 No. 2 (2022): Bandung Conference Series: Pharmacy
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (162.943 KB) | DOI: 10.29313/bcsp.v2i2.4817

Abstract

Abstract. The genus Brassica is one of the largest genera of flowering plants, which has more than 3000 species distributed worldwide. In addition, in this genus Brassica there are many types of vegetables that are beneficial to human life. This literature search aims to determine the potential of vegetables from the genus Brassica such as cabbage, broccoli and radishes as antibacterial, to know the extraction method, to know their secondary metabolites and the mechanism of action of secondary metabolites produced by the genus Brassica as antibacterial. The methodology used is a library search on the website. The results of the literature search showed that the Brassica genus of cabbage, broccoli and radish had antibacterial potential against Staphylococcus aureus, Staphylococcus epidermidis, Bacillus subtilis, Staphylococcus mutans, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia. Shigella sonei, Salmonella paratyphi, Salmonella thypi dan Proteus vulgaris. With maceration and Soxhlet extraction methods and suspected antibacterial compounds derived from the genus Brassica, namely glucosinolates which act as typical compounds from the genus Brassica and other compounds flavonoids, polyphenols, tannins, saponins and alkaloids. With the mechanism of the compound inhibits the synthesis of bacterial cell walls. Abstrak. Genus Brassica merupakan salah satu genus tanaman berbunga terbesar, yang memiliki lebih dari 3000 spesies yang terdistribusi di seluruh dunia. Selain itu dalam genus Brassica ini terdapat banyak jenis sayuran yang bermanfaat bagi kehidupan manusia. Penelusuran pustaka ini bertujuan untuk mengetahui potensi sayuran dari genus Brassica jenis kubis, brokoli dan lobak sebagai antibakteri, mengetahui metode ekstraksi nya, mengetahui senyawa metabolit sekunder nya dan mekanisme kerja senyawa metabolit sekunder yang dihasilkan genus Brassica sebagai antibakteri. Dengan metodelogi yang digunakan yaitu penelusuran pustaka pada website. Hasil penelusuran pustaka yang diperoleh menunjukkan bahwa genus Brassica jenis kubis, brokoli dan lobak memiliki potensi antibakteri terhadap Staphylococcus aureus, Staphylococcus epidermidis, Bacillus subtilis, Staphylococcus mutans, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia. Shigella sonei, Salmonella paratyphi, Salmonella thypi dan Proteus vulgaris. Dengan metode ekstraksi maserasi dan Soxhlet dan diduga antibakteri berasal dari senyawa khas genus Brassica yaitu glukosinolat yang berperan sebagai senyawa khas dari genus Brassica dan senyawa lain flavonoid, polifenol, tanin, saponin dan alkaloid. Dengan mekanisme senyawa menghambat sintesis dinding sel bakteri.
Penentuan Nilai Persentase Eritema dan Pigmentasi Ekstrak Etanol Daun Jambu Mete (Anacardium occidentale L.) secara Invitro Satyawati; Livia Syafnir; Vinda Maharani Patricia
Bandung Conference Series: Pharmacy Vol. 3 No. 2 (2023): Bandung Conference Series: Pharmacy
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsp.v3i2.8510

Abstract

Abstract. Sunlight plays an important role in survival, especially humans, but prolonged exposure to sunlight can harm the skin due to ultraviolet radiation. The use of sunscreen is one way to protect the skin from the harmful effects of UV rays. The ethanol extract of cashew leaves contains flavonoid compounds which have potential as sunscreens because they have chromophore groups that are able to absorb UV rays thereby reducing the intensity on the skin. This study aims to determine the percentage transmission of erythema and the percentage transmission of pigmentation of the ethanol extract of cashew leaves in vitro using the spectrophotometric method. On the purchase of % Te and % Tp concentrations of 200 ppm, 400 ppm, 600 ppm, 800 ppm and 1000 ppm, the UV A and UV B sunblock categories showed the best values ​​of % Te 0.004 % and % Tp 0.0177 %. Based on these results indicate that the higher the concentration, the better the protection power of the percentage of erythema transmission and the percentage of pigmentation transmission.. Keywords: Sunscreen, Cashew leaves, %Te, % Tp Abstrak. Sinar matahari sangat berperan penting dalam keberlangsungan hidup terutama manusia, tetapi paparan sinar matahari yang terlalu lama dapat membahayakan kulit karena radiasi sinar ultraviolet. Penggunaan tabir surya merupakan salah satu cara untuk melindungi kulit dari pengaruh buruk sinar UV. Ekstrak etanol daun jambu mete mengandung senyawa flavonoid yang memiliki potensi sebagai tabir surya karena memiliki gugus kromofor yang mampu menyerap sinar UV sehingga mengurangi intensitas pada kulit. Penelitian ini bertujuan untuk mengetahui nilai persen transmisi eritema dan persen transmisi pigmentasi ekstrak etanol daun jambu mete secara in vitro dengan menggunakan metode spektrofotometri. Pada penentuan nilai % Te dan % Tp dari konsentrasi 200 ppm, 400 ppm, 600 ppm, 800 ppm dan 1000 ppm menunjukkan kategori sunblock UV A dan UV B dengan nilai terbaik % Te 0,004 % dan % Tp 0,0177 %. Berdasarkan hasil tersebut menunjukkan bahwa semakin tinggi konsentrasi maka daya proteksi dari persen transmisi eritema dan persen transmisi pigmentasi semakin baik. Kata Kunci : Tabir surya, Daun jambu mete, %Te, % Tp
Co-Authors Abdurrasyid Fadhlurrahim Adinda Fitri Salsabila Ainul Fatihah Halim Aqila Dliya Zhafira Eky Bagus Wahyudi Fairuz Rifdah Permanasari Faqih Radina G.C. Eka Darma Geofanny Mozataufika Indra Topik Maulana Inge Aprianti Kiki Mulkiya Yuliawati Miaranti Tia Azhariani Mohammad Ihsan Abdurrozak Muhammad Daffa Adilah Muhammad Fadhil Safari Ratih Aryani Reza Abdul Kodir Rifa Safira Rizza F. Nurasyfa Robby Prayitno salsabila soedradjat Sani Ega Priani Satyawati Sri P. Fitraningsih Sri Peni Fitrianingsih Sri Puan Hanum Tasya Luthfiyyah Tia Nur Setianty Via Pujiah Vinda Maharani Patricia Yani Lukmayani