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All Journal International Journal of Public Health Science (IJPHS) Journal of Food and Pharmaceutical Science EKSAKTA: Journal of Sciences and Data Analysis Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Jurnal Pendidikan dan Konseling Community Empowerment Jurnal Pengabdian dan Peningkatan Mutu Masyarakat (JANAYU) Journal of Halal Science and Research Journal of Global Pharma Technology Journal of Food and Pharmaceutical Sciences
Mustofa Ahda
Fakultas Farmasi Universitas Ahmad Dahlan
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Journal : Journal of Global Pharma Technology

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Evaluation the Fractions from Extract Ethanol Psidium Guajava Leaves on Total Phenolic Content, Antioxidant Activity and Its Antibacterial Activity of Staphylococcus Aureus. Mustofa Ahda
Journal of Global Pharma Technology Volume 11 Issue 01.
Publisher : Journal of Global Pharma Technology

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Abstract

Objective: The aims of this research to find the potential extract and fraction from ethanol extract of Psidium Guajava L for natural antioxidant and antibacterial. The extract and fraction of Psidium Guajava L was analyzed the phenol total content, antioxidant activity and its antibacterial. Methods: The ethanol extract of Psidium Guajava L was extraxted using n hexane, ethyl acetate and water. The all fraction and ethanol extract of Psidium Guajava L was determined the scavenging activity, penolic compound. The scavenging activity was determined by DPPH method. The phenolic compound was determined with Folin-Ciocalteu method. Results: The result of this research showed that the fraction of ethyl acetate has highest antioxidant activity with the value is 9.07 µg/mL. It is also supported by the result of screening phytochemical that ethyl acetate fraction contains mostly complete of chemical substances. However, The highest total phenol content was found in water fraction with phenolic content of 26%. The anbacterial activity of ethanol 96% extract of Psidium guajava leaves and ethyl acetate fraction have a highly activity to inhibit the Staphylococcus Aureus. Conclusion: The fraction of ethyl acetate has a highest of antioxidant activity, although it doesn’t have highest of total phenolic content. The highest of total fenolic content from water fraction is 26%. The scheme of antibacterial activities potential of Guajava extracts are ethanol 96% extract = ethyl acetate fraction > n-hexane fraction = water fraction
Co-Authors Adi Permadi Ahmad Ahid Mudayana Ananda Ranu Bachtiar Any Guntarti Any Guntarti Aprilia Kusbandari, Aprilia Aulia Nur Rahma Devi Sahyuni Putri Koto Diffah Hanim Eko Sri Kunarti Elza Naura Syafitri Fiqrirozi Fiqrirozi Gina Noor Habibah Ikawati, Retty Ilmiyatun Rasyidah Khalif Fathan Muzakki Kusnandar Kusnandar Mas Ulfah Lestari Muhimmatul Husna Nina Salamah Noor Syahdan Fitrianto Nurkhasanah Mahfudh Palupi Melati Pangastuti Suhendra Suhendra Sunarti Sunarti Sutarno Sutarno Sutarno, Sutarno Syaeful Akbar Padya Tomy Hardianto Vania Insani Syita Harmony Yeni Triwidyastuti Yolanda Waldatul Marwa Yuni Andriani Zainab Zainab