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Anggraeni, Reti
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Health Professions Medicine & Pharmacology Public Health

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Diaper Dermatitis Tri Irfanti, Rakhma; Imelda Betaubun, Ance; Arrochman, Ferry; Fiqri, Ahmad; Rinandari, Ummi; Anggraeni, Reti; Yustin Ellistasari, Endra
Cermin Dunia Kedokteran Vol 47, No 5 (2020): CME - Continuing Medical Education
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (877.502 KB) | DOI: 10.55175/cdk.v47i5.362

Abstract

Diaper dermatitis (juga dikenal sebagai ruam popok, nappy rash, atau dermatitis iritan karena popok) adalah istilah umum untuk meggambarkan inflamasi akut pada area terkena popok; kondisi ini umumnya terjadi pada bayi. Etiologi dermatitis popok adalah multifaktorial. Diagnosis dan penatalaksanaan tepat mendapatkan hasil optimal; diperlukan kerjasama antara orang tua, pengasuh, dan tenaga medis.Diaper dermatitis (also known as diaper rash, nappy rash, or irritant dermatitis due to diapers) is a general term used to describe acuteinflammation in an area affected by a diaper; this condition generally occurs in infants. The etiology of diaper dermatitis is multifactorial. Proper diagnosis and management get optimal results; collaboration between parents, caregivers, and medical personnel is needed.
Profil Penggunaan Kortikosteroid Sistemik untuk Terapi Sindrom Stevens Johnson (SSJ) – Nekrolisis Eepidemal Toksik (NET) di Instalasi Rawat Inap RSUD DR. Moewardi Surakarta, Indonesia - Januari 2016 -Desember 2017 Tri Irfanti, Rakhma; Imelda Betaubun, Ance; Fiqri, Ahmad; Anggraeni, Reti; Rinandari, Ummi; Kariosentono, Harijono
Cermin Dunia Kedokteran Vol 48, No 4 (2021): Dermatologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (128.835 KB) | DOI: 10.55175/cdk.v48i4.1364

Abstract

Latar belakang: Nekrolisis epidermal disebut Sindrom Stevens Johnson (SSJ) apabila yang terlibat kurang dari 10% dari area tubuh, 10% sampai 29% disebut SSJ overlap NET dan lebih dari 30% NET. Tujuan : Untuk mengetahui gambaran umum pasien SSJ-NET serta penggunaan kortikosteroid sistemik di Instalasi Rawat Inap RSUD Dr. Moewardi Surakarta periode Januari 2016 – Desember 2017. Metode : Studi deskriptif retrospektif dengan populasi dan sampel penelitian pasien rawat inap di Instalasi Rawat Inap RSUD Dr. Moewardi, Surakarta, periode Januari 2016 – Desember 2017. Sampel menggunakan data sekunder dari status rekam medis di Instalasi Rawat Inap RSUD Dr. Moewardi Surakarta. Hasil: Total pasien 26 orang terutama berusia 46 – 55 tahun dan 56 – 65 tahun (23%). Laki-laki lebih banyak (57%). Diagnosis SSJ (61%) terbanyak dibandingkan SSJ overlap NET (19%) ataupun NET (19%). Hipertensi sebagai penyakit penyerta terbanyak (15%). Keterlibatan mukosa terbanyak pada mulut (88 %) dan penyebab terbanyak SSJ-NET melibatkan lebih dari satu macam obat (53%). Obat penyebab yang dicurigai terutama adalah antibiotik golongan sefalosporin dan parasetamol (23%). Rerata lama terapi deksametason adalah 10 hari dengan dosis rata-rata 25 mg per hari. Simpulan: Pengobatan kortikosteroid sistemik pada kasus SSJ – NET di RSUD dr. Moewardi Surakarta pada umumnya menghasilkan perbaikan klinis dengan rata-rata perawatan 10 hari dan dosis rata-rata deksametason 25 mg per hari.Background: Epidermal Necrolysis is classified into several degree of severity based on the area of the body involved, below 10% is SJS, 10% - 29% is SJS overlap TEN and 30% is TEN. Objective: To provide general description of SJS-TEN patients and systemic corticosteroids therapy in Dr.Moewardi General Hospital Surakarta January 2016 - December 2017. Methods: A retrospective descriptive study on in-patients in Dr. Moewardi General Hospital Surakarta between January 2016 and December 2017. Results: Total sample was 26 patients, mostly male (57%) in 46 - 55 year-old and 56 - 65 year-old (23%). The most common diagnosis was SJS (61%) followed by SJS overlap TEN (19%) and TEN (19%). Hypertension was the most frequent comorbid disease (15%). Mostly affected was mouth mucosa (88%) and caused by mostly more than one drug (53%). Suspected causative drugs were mostly cephalosporin and paracetamol (23%). The average duration of dexamethason therapy was 10 days with an average dose 25 mg per day. Conclusion: SSJ - NET cases in Dr. Moewardi General Hospital Surakarta were mostly treated with systemic corticosteroids for an average of 10 days and an average dose of dexamethason 25 mg per day.
Terapi Probiotik (Lactococcus lactis) Topikal untuk Akne Vulgaris: Kasus Serial Anggraeni, Reti; Rosita, Fiska; Kusumawardani, Arie
Cermin Dunia Kedokteran Vol 48, No 1 (2021): Penyakit Dalam
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (565.72 KB) | DOI: 10.55175/cdk.v48i1.1265

Abstract

Latar Belakang: Akne vulgaris (AV) adalah penyakit inflamasi kulit kronik yang mengenai unit pilosebasea, mengakibatkan kelainan non-inflamasi berupa komedo dan tanda inflamasi. Mikroba kulit seperti Propionibacterium acnes (P. acnes) dan Malassezia spp. berperan dalam patogenesis AV. Laporan kasus ini mengenai efek terapi probiotik topikal terhadap perbaikan lesi AV. Kasus: Tiga pasien AV diberi terapi tabir surya (SPF 30) dan probiotik topikal selama 4 minggu tanpa terapi standar AV. Pemeriksaan swab dilakukan pada semua pasien untuk melihat jenis dan jumlah mikrobiom. Hasilnya tidak ditemukan kolonisasi P. acnes tetapi terjadi penurunan jumlah dan derajat keparahan lesi pada semua pasien. Terapi yang sama dilanjutkan selama 4 minggu pada satu pasien. Kolonisasi P. acnes hanya ditemukan pada awal terapi. Evaluasi klinis yaitu penurunan jumlah lesi AV dan kulit wajah menjadi lebih halus dan lembap. Ringkasan: Probiotik topikal memberikan hasil baik pada kasus AV.Introduction: Acne vulgaris (AV) is chronic inflammatory skin disease affecting pilosebaceous unit, resulting in non-inflammatory disorders in the form of comedones and signs of inflammation. Skin microbes such as Propionibacterium acnes (P. acnes) and Malassezia spp. play role in the AV pathogenesis. This paper reports the effects of topical probiotic on AV lesions improvement. Case: Three AV patients were given sunscreen (SPF 30) and topical probiotics for 4 weeks without standard AV therapy. Swab examination showed no P. acnes colonization but the amount and severity of lesions in all patients were decreased. One patient then continued the same therapy for 4 weeks; P. acnes colonization was only found at the beginning of therapy. Clinical evaluation resulted in decreasing lesions and smoother and moisturized facial skin. Summary: Topical probiotic gives good results in AV.
Co-Authors Ahmad Fiqri, Ahmad Arrochman, Ferry Imelda Betaubun, Ance Kariosentono, Harijono Kusumawardani, Arie Rinandari, Ummi Rosita, Fiska Tri Irfanti, Rakhma Yustin Ellistasari, Endra