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All Journal The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia
Lie Khie Chen
Unknown Affiliation
Health Professions Medicine & Pharmacology

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Correlation between Proper Antibiotics Administration to Community Acquired Pneumonia Patients Based on Alur Gyssens with Clinical Response Rumende, Cleopas Martin; Chen, Lie Khie; Karuniawati, Anis; Bratanata, Joyce; Falasiva, Rezyta; Sitorus, Truly Panca; Susanto, Erwin Christian
Jurnal Penyakit Dalam Indonesia Vol. 6, No. 2
Publisher : UI Scholars Hub

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Abstract

Introduction. The proper of antibiotics treatment will increase the improvement of the patient with community-acquired pneumonia (CAP) and also counteract antimicrobial resistance. Community-Acquired Pneumonia is commonly found in Indonesia with an incidence of 2.4%. This study aimed to determine the proper of antibiotic selection for CAP based on IDSA-ATS 2007 guidelines with Gyssens method and evaluate the relationship between the proper of antibiotic treatment with the clinical response of patients. Methods. A retrospective cohort study was conducted with secondary data from the previous study. Study was conducted in three hospitals in Jakarta, namely Cipto Mangunkusumo General Hospital, Budhi Asih Hospital, and Gatot Subroto Hospital between September 2016 and November 2017. Results. From 151 patients, the appropriate of the first antibiotic treatment, including category 0 and 1 was found in 38 patients (25.2%), while for inappropriate one (category II-V) was in 113 patients (74.8%) mainly due too short antibiotic treatment. For the second antibiotic given to 54 patients, appropriate treatment was found in 15 patients (9.9%). There was no correlation between the accuracy of both antibiotics treatment in CAP based on Gyssens method with clinical response of the patients (first antibiotic treatment: RR=0,970 (95% CI: 0,80 – 1,16), p=0,738; second antibiotic treatment: RR=1,194 (95% CI: 0,648 – 2,20), p=1,00). Conclusion. There was no correlation between the accuracy of antibiotics treatment in CAP based on Gyssens method with clinical response of the patients.
Co-Authors A.A. Ketut Agung Cahyawan W Adeputri Tanesha Idhayu Adityo Susilo, Adityo Alvina Widhani, Alvina Andree Kurniawan Anis Karuniawati Annisa, Firda C. Martin Rumende, C. Martin Ceva W Pitoyo Cleopas Martin Rumende Dana Dharaniyadewi, Dana Danasasmita, Gantira Diana Aulia Djoko Widodo Edwin Wijaya, Edwin Erni J Nelwan, Erni J Esthika Dewiasty, Esthika Evy Yunihastuti Falasiva, Rezyta Gurmeet Singh Herdiman T Pohan Herdiman T. Pohan Herikurniawan, Herikurniawan Jasirwan, Chyntia OM Joyce Bratanata, Joyce Kemal Fariz Kalista, Kemal Fariz Leonard Nainggolan Maksum, Maradewi Marcellus Simadibrata Marcellus Simadibrata Mira Yulianti, Mira Murdani Abdullah Nathanael, Jason Pasaribu, Adeline Prima Yuriandro Pringgodigdo Nugroho, Pringgodigdo Retno Wahyuningsih Robert Sinto Shakinah, Sharifah Sitorus, Truly Panca Soroy Lardo Suhendro Suhendro Suhendro Suwarto, Suhendro Susanto, Erwin Christian Timan, Ina Sutanto Wicaksana, Bramantya Widayat Djoko Santoso, Widayat Djoko Wirawan Hambali, Wirawan