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All Journal Nurse Media Journal of Nursing Jurnal Mahasiswa Teknik Sipil Universitas Tanjungpura Althea Medical Journal Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan Jurnal Kedokteran Indonesian Journal of Cancer
Budi Darmawan
Department of Nuclear Medicine Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung
Civil Engineering, Building, Construction & Architecture Education Health Professions Medicine & Pharmacology Nursing

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Telaah Awal Pemetaan Indikasi Pemeriksaan 18F-FDG PET/CT di RS Kanker "Dharmais" dengan Pedoman Appropriateness Criteria dari IAEA KARDINAH, KARDINAH; HIKMAWATI, SARININGSIH; HASAN, ROSALINA; DARMAWAN, BUDI
Indonesian Journal of Cancer Vol 6, No 4 (2012): Oct - Dec 2012
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

Pemanfaatan pemeriksaan dengan biaya mahal memerlukan health technology assessment (HTA) sehingga memberikan dampak yang optimal bagi tata laksana pengobatan pasien selanjutnya. Pedoman dari International Atomic Energy Agency (IAEA) yang diterapkan dalam pelaksanaan pemeriksaan 18F-FDG PET/CT scan bertujuan sebagai telaah awal pemetaan indikasi sehingga dapat dilakukan perbaikan dan pengembangan di masa mendatang.Dilakukan evaluasi retrospektif terhadap 116 pasien yang melakukan pemeriksaan pada Mei sampai Agustus 2012 di RS Kanker “Dharmais”. Indikasi pemeriksaan dikelompokkan sesuai dengan rekomendasi IAEA, yaitu diagnosis, penentuan stadium, evaluasi respons terapi, dan evaluasi rekurensi.Hasilnya menunjukkan persentase pemeriksaan 18F-FDG PET/CT scan dengan indikasi evaluasi respons terapi sebesar 48,2%, pada limfoma maligna 12,9% dan kanker payudara 8,6%. Sedangkan evaluasi adanya rekurensi sebesar 37,9%, masing-masing pada kanker payudara 15,5% dan limfoma maligna 4,3%. Indikasi penentuan stadium adalah 9,4% dan diagnosis 4,3%.Kesimpulannya, pemeriksaan 18F-FDG PET/CT/CT merupakan modalitas yang penting dalam evaluasi terapi dan rekurensi pada pasien kanker bila diterapkan sesuai dengan indikasi yang jelas. Dengan demikian, perubahan tata laksana yang berguna untuk keberhasilan pengobatan pasien dapat tercapai.Kata kunci: 18F-F PET/CT, indikasi pemeriksaan, evaluasi respons terapi, evaluasi rekurensi.
Community Knowledge and Perception on Autopsy in Jatinangor, West Java from August to October 2013 Carwen, Siaw; Fitrasanti, Berlian Isnia; Darmawan, Budi
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Autopsy rate had declined dramatically throughout the world for the past decades. This phenomenon has raised concerns of the medical world. Factors that contributed to this decline include lack of knowledge regarding autopsy among the people, religious reasons, unenthusiastic pathologists and others. This study was conducted to discover the community knowledge and perception of autopsy at Jatinangor, West Java.Methods: A descriptive study was conducted in Jatinangor during the period of August to October 2013. One hundred and ten respondents were included in this study by random sampling. After written informed consent, respondents were given a questionnaire. Collected data were presented in the form of percentages in tables.Results: Most of the respondents were from the age group of 41–50, entrepreneur and senior high school. Eighty seven (79.09%) respondents had heard about the term “autopsy”, but only 66 (75.86%) of them claimed that they knew about autopsy. However, only 53 from 87 respondents (60.92%) truly knew about autopsy. From 110 respondents, 58  (52.72%) of them knew the reasons to perform autopsy. Fifty seven (51.81%) respondents would allow autopsy to be performed on themselves or family members. The main reason was given to discover the exact cause of death. The reasons of  autopsy refusal were afraid of religion concerns and respect for the human body.Conclusions: There are still members of the community who do not know about autopsy and its purposes. It is recommended that the government improves the community knowledge through various activities and programs. DOI: 10.15850/amj.v2n3.522
Knowledge of Personal Hygiene among Food Handlers in Canteen at Faculty of Medicine, Universitas Padjadjaran, October to November 2012 Zarisha, Drasthya; Darmawan, Budi; Raksanagara, Ardini S.; Setiawati, Elsa Pudji
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Althea Medical Journal

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Abstract

Background: Food borne diseases are caused by contamination of pathogenic microorganism and are still a major health problem throughout the world. There are 1,8 billion cases of diarrhea which mostly were caused by food contamination in 2005. Food handlers are at risk of contaminating microorganism towards food they handle. The process of transmission can be prevented by practicing good hygiene while processing and handling food. The objective of this study was assessing knowledge among food handlers regardingtheir personal and food hygiene at canteen in Faculty of Medicine, Universitas Padjadjaran.Methods: A descriptive study was conducted during the period of October to November 2012 to 14 food handlers in the Canteen at Faculty of Medicine, Universitas Padjadjaran using 26 validated questions divided into 3 major parts, 14 questions for knowledge of hand washing, 9 questions for knowledge of utilization of clean water and 3 questions for knowledge of waste management. The scores were classified as good, moderate, and poor. Data were analyzed using frquency distribution.Results: Majority of the respondents was male and common age group was 20–29 years old. Eight of the respondents were senior high school graduates. Based on working experience, majority of food handlers had been working for one and three years. None of the respondents had good knowledge. Only 12 and 2respondents had moderate and poor knowledge, respectively.Conclusion: None of the respondents had good knowledge regarding hand washing, utilization of clean water and waste management. Therefore, there is a need in providing more education about those aspects.[AMJ.2015;2(1):245–9]
Negative Air Pressure on Wet Cupping in Decreasing Blood Pressures in Hypertensive Patients Darmawan, Budi; Fatmasari, Diyah; Pujiastuti, Rr. Sri Endang
Nurse Media Journal of Nursing Vol 7, No 2 (2017): (DECEMBER 2017)
Publisher : Department of Nursing, Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (397.333 KB) | DOI: 10.14710/nmjn.v7i2.15177

Abstract

Background: Wet cupping, furthermore mentioned cupping, decreases blood pressures through the level of negative air pressures added by hydrostatics filtration pressure to reinforce the power of fluids filtration in capillaries. However, an appropriate negative air pressure to decrease blood pressure remains an uncertainty.Purpose: This study aimed to analyze negative air pressure differences on cupping in decreasing blood pressures in hypertensive patients.Methods: This is a quasi-experimental design conducted in three Community Health Centers in Langsa City, Aceh, Indonesia. The samples were 36 hypertensive males with age from 45 to 55, who were randomly stratified into two groups with cupping pressures 400 mbar (n=18) as the control group; and 540 mbar (n=18) as the intervention group. The cupping session was performed to each group on T1 (alkahil) point and in the middle line of both shoulders blade points. The systolic blood pressure (SBP) and diastolic blood pressures (DBP) were measured by validated automatic sphygmomanometer. The follow-up periods were one week and two weeks. The data were then analyzed by repeated measures ANOVA.Results: Cupping pressure of 400 mbar decreased the mean of SBP and DPB with a p-value of 0.450 and 0.026, respectively after two weeks of intervention. Meanwhile, cupping pressure of 540 mbar decreased the mean of SBP and DBP with a p-value of 0.006 and 0.057, respectively. Tests of within-subjects resulted in the p-value of 0.250 (SBP) and 0.176 (DBP) after two weeks of intervention. There were no significant differences in SBP and DBP between the intervention group and the control group.Conclusion: The cupping pressure between 400 mbar and 540 mbar could reduce blood pressure; however, the cupping pressure of 540 mbar yielded greater effect in decreasing blood pressure than the 400 mbar. Negative air vacuum pressure loads on cupping to decrease blood pressure should be considered between 400 to 540 mbar, and further studies are needed.
PENGARUH LATIHAN INTERVAL TRAINING TERHADAP DAYA TAHAN PARU DAN JANTUNG PADA TIM BASKET PUTRA SMKN 7 PEKANBARU Darmawan, Budi; ', Ramadi; Juita, Ardiah
Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan Vol 4, No 2 (2017): Wisuda Oktober 2017
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan

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Abstract

Abstract: The problem in this study is the lack of endurance at the time of two-point shots during training and at O2SN tournaments conducted in school and o2sn field in the basketball senapelan. Based on these problems the researcher gives interval training training. This study aims to determine whether there is an effect of training interval training on the endurance of the lungs and heart on the men's basketball team SMKN 7 Pekanbaru, so that when the first quarter and second physical condition of the player is still excellent, enter the third quarter and the fourth player often exchange players and visible Also the player is very tired. The form of this research is experimental (experimental) research, with population of men's basketball team SMKN 7 Pekanbaru, the data in this study is the entire population of 12 people. The instrument performed in this study is a 400 meter run, which aims to measure respiratory durability (cardiovascular). After that, the data were processed with statistics, to test the normality by lilifors test at a significant level of α (0.05). The hypothesis proposed is the effect of training interval training on the endurance of lung and heart. Based on the statistical data analysis, there is an average pree-test of 29.53 and the post-test average of 32.79, then the data is normal with an increase of 3.49. Based on t test analysis yielded Thitung equal to 2,251 and Ttabel 1,895, mean Thitung> T table. Thus, there is the Effect of Interval Training Training Against Lung and Heart Resistance at Basketball Team of SMKN 7 Pekanbaru.Keywords: Interval Training, endurance of lungs and heart
PEMETAAN SOSIAL EKONOMI MASYARAKAT DI DESA PARIT BARU KECAMATAN SUNGAI RAYA KABUPATEN KUBU RAYA Darmawan, Budi; Pratiwi, Nana Novita; Chairunnisa, -
JeLAST : Jurnal PWK, Laut, Sipil, Tambang Vol 6, No 2 (2019): JURNAL MAHASISWA TEKNIK SIPIL EDISI JUNI 2019
Publisher : JeLAST : Jurnal PWK, Laut, Sipil, Tambang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (427.24 KB) | DOI: 10.26418/jelast.v6i2.35431

Abstract

Desa Parit Baru Kecamatan Sungai Raya merupakan desa kurang berkembang. Saat ini terdapat 5226 jiwa masyarakat kurang mampu berdasarkan data Dinas Sosial dan Pemberdayaan Masyarakat. Selain itu diketahui bahwa keterampilan dan pengetahuan masyarakat masih terbatas. Penelitian ini bertujuan untuk mengidentifikasi dan memetakan kondisi sosial ekonomi di Desa Kabupaten Kubu Raya. Metode analisis menggunakan metode kualitatif dengan pendekatan deskriptif. Variabel Sosial terdiri dari partisipasi, pendidikan, norma-norma, dan keamanan kemudian Variabel Ekonomi terdiri dari pekerjaan, pendapatan, dan kesejahteraan. Hasil klasifikasi kondisi sosial di Desa Parit Baru tergolong cukup berdasarkan dari tingkat partisipasi, tingkat pendidikan, norma-norma dan keamanan di desa Parit Baru. Hasil Klasifikasi kondisi ekonomi tergolong baik berdasarkan dari pekerjaan masyarakat, kependudukan, pendapatan dan tingkat kesejahteraan masyarakat dilihat dari pengeluaran, jumlah anggota keluarga yang bekerja dan pendapatan yang mencukupi kehidupan keluarga. Hasil dari penelitian dapat disimpulkan bahwa keadaan sosial ekonomi di Desa Parit Baru sudah tergolong cukup baik. Kata kunci: pemetaan, sosial, ekonomi, parit baru.
PEPTIDE RECEPTOR RADIONUCLIDE THERAPY Hidayatullah, Rian; Budiawan, Hendra; Darmawan, Budi; Affandi, Erwin
Jurnal Kedokteran Vol 10 No 1 (2021): volume 10 nomor 1 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i1.480

Abstract

Peptide receptor radionuclide therapy (PRRT) is an effective and usually well-tolerated treatment for unresectable or metastatic neuroendocrine tumors expressing somatostatin receptors. Somatostatin analog which is labeled by ?- or ?-emitting radionuclide binds specifically to SSTRs abnormally expressed in NETs. The two radiopharmaceuticals most commonly used for PRRT are 90Y-DOTATOC and 177Lu-DOTATATE which have been demonstrated to provide an effective tumor response and symptom relief with positive impact on survival. Chronic side effects on the kidneys and bone marrow are generally mild. The radiopharmaceuticals is internalized into the cell for the irradiation. Furthermore, the long half-life of the analog maintains a persistent therapeutic effect. Different approaches are now under evaluation to improve PRRT efficacy, it may be expected that the use of PRRT will increase in the coming years.
Somatostatin Hidayatullah, Rian; Budiawan, Hendra; Darmawan, Budi; Affandi, Erwin
Jurnal Kedokteran Vol 10 No 2 (2021): Jurnal Kedokteran Juni 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i2.482

Abstract

Somatostatin, also known as growth hormone-inhibiting factor (GIF) or somatotropin release-inhibiting factor (SRIF), is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation. Somatostatin can be regarded as secretory pan-inhibitory,because it can inhibit secretion of almost all endocrine and exocrine glands. Somatostatin has 2 active forms (somatostatin-14 and 28), but the short half-life of the hormone was one of the reasons why the native hormone was not feasible for routine clinical practice. Somatostatin analog was synthesized for the first time in 1980-1982 and proved to be more resistant to degradation and more potent than native hormone. There are five somatostatin receptors (SSTR1-5). The genes encoding human SSTR1-5 are located in chromosome 14q13, 17q24, 22q13.1, 20p11.2 and 16p13.3. SSTR expression pattern and complex signaling make somatostatin be such an extraordinary neurotransmitter and hormone. The potent inhibitory action of SSTR on cellular processes such as secretion, proliferation, and apoptosis is the reason for somatostatin to be the target for therapy development. Radiopharmaceuticals used for therapy consist of three parts: somatostatin analog, chelator, and radionuclide (alpha or beta-emitting). Combinations of different peptides, chelators, and radionuclides have been tested in vitro and/or in vivo for their use in peptide receptor radionuclide therapy (PRRT). These compounds are able to irradiate tumors and their metastases via the internalization through a specific receptor subtype which is generally overexpressed on the cell membrane.
Co-Authors ', Ramadi Ardiah Juita Ardini S. Raksanagara, Ardini S. Berlian Isnia Fitrasanti Chairunnisa, - Diyah Fatmasari Drasthya Zarisha, Drasthya Elsa Pudji Setiawati Erwin Affandi Hendra Budiawan, Hendra KARDINAH KARDINAH, KARDINAH Pratiwi, Nana Novita Pujiastuti, Rr. Sri Endang Rian Hidayatullah ROSALINA HASAN, ROSALINA SARININGSIH HIKMAWATI, SARININGSIH Siaw Carwen, Siaw