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All Journal Jurnal Ilmiah Farmasi Natural Science: Journal of Science and Technology Pharmaciana: Jurnal Kefarmasian The Journal of Pure and Applied Chemistry Research Jurnal Farmasi Klinik Indonesia Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Indonesian Journal of Chemistry Jurnal Aplikasi Teknologi Pangan Jurnal Kimia dan Kemasan
Dion Notario
Universitas Katolik Indonesia Atma Jaya
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

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Journal : Pharmaciana: Jurnal Kefarmasian

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Penelusuran aktivitas antibakteri, antioksidan, dan sitotoksik fungi endofit genus fusarium sp. diisolasi dari daun meniran (Phyllantus niruri Linn.) rollando, Rollando; Aditya, Martanty; Notario, Dion; Monica, Eva; Sitepu, Rehmadanta
Pharmaciana Vol 7, No 1 (2017): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (350.762 KB) | DOI: 10.12928/pharmaciana.v7i1.5644

Abstract

Endophytic fungi used as a new resource to produce bioactive compounds such as antibacterial, antioxidant and anticancer. This study aimed to analyze the antibacterial, antioxidant, cytotoxic fraction of the separation ethyl acetate extract of mycelium of endophytic fungi genus Fusarium sp. Diethyl ether fraction showed high antibacterial activity in E.coli (20,75 µg/mL), S.typhi (35,08 µg/mL), and S.aureus (51,96 µg/mL). Test showed that the antioxidant activity of ethanol 96% fraction has highest antioxidant activity and total phenolic content (75,85 ± 0.87 mg GAE). Cytotoxic test on T47D breast cancer cells showed that the fraction of diethyl ether have highest activity with IC50 of 10,16 ± 0,88 µg /mL.
Co-Authors Agustina Dwi Retno Nurcahyanti Alfanaar, Rokiy Arief Rahman Hakim Endang Lukitaningsih Eva Monica, Eva Fathul Jannah Fibe Y. Cesa Fibe Yulinda Cesa Intan Harmae Setiawan Kestrilia Rega Prilianti Martanty Aditya, Martanty Monica, Eva Rehmadanta Sitepu Rehmadanta Sitepu Rehmadanta Sitepu Rianita Pramitasari Rollando, Rollando Sitepu, Rehmadanta Sudibyo Martono Zullies Ikawati