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All Journal Jurnal Kimia (Journal of Chemistry) METAMORFOSA Journal of Biological Sciences Media Ilmiah Teknologi Pangan (Scientific Journal of Food Technology) Jurnal Kimia dan Kemasan HIGIENE: Jurnal Kesehatan Lingkungan Jurnal Media Sains Acta Chimica Asiana Jurnal Sains dan Edukasi Sains Quimica : Jurnal Kimia Sains dan Terapan Jurnal Kimia dan Kemasan Sanitasi: Jurnal Kesehatan Lingkungan Seminar Ilmiah Nasional Teknologi, Sains, dan Sosial Humaniora (SINTESA) Seminar Nasional Aplikasi Iptek (SINAPTEK) Jurnal Kesehatan Terpadu JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Jurnal aplikasi IPTEK
Ni Luh Utari Sumadewi
Universitas Dhyana Pura
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Energy Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : METAMORFOSA Journal of Biological Sciences

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Potensi Ekstrak Daun Akasia (Acacia auriculiformis) sebagai Antifungi pada Candida albicans dan Identifikasi Golongan Senyawanya Ni Kadek Yunita Sari; Ni Luh Utari Sumadewi
Metamorfosa: Journal of Biological Sciences Vol 6 No 2 (2019)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa.2019.v06.i02.p02

Abstract

Infections caused by Candida albicans have been increased dramatically worlwide. Acacia auriculiformis is an Indonesian Indigenous plant which has limited use only for fiber needs, especially for paper industry raw materials and as a protective plant. The use of Acacia auriculiformis as a traditional medicine, especially as an antifungal, is rarely reported. The purpose of this study was to determine the potential of acacia leaf extract (Acacia auriculiformis) as an antifungal against Candida albicans growth and identification of its compound class. The potential of acacia leaf extract as antifungal was tested by Kirby-Bauer method using paper discs and identification of acacia leaf compound class was carried out by phytochemical test. The results showed that acacia leaf extract (Acacia auriculiformis) concentration of 1%, 5%, 10% have potential to be an antifungal against the growth of Candida albicans and the methanol extract compound of acacia leaves consists of saponins, tannins, alkaloids, flavonoids, steroids and phenolics. Keyword: Candida albicans, Acacia auriculiformis, antifungal
Aktivitas Antifungi Saponin Bunga Kamboja Putih (Plumeria acuminata) pada Candida albicans ATCC 10231 Ni Kadek Yunita Sari; Ni Luh Utari Sumadewi
Metamorfosa: Journal of Biological Sciences Vol 8 No 1 (2021)
Publisher : Prodi Magister Ilmu Biologi, Fakultas MIPA, Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/metamorfosa.2021.v08.i01.p07

Abstract

Candida albicans is the main cause of candidiasis in Indonesia. Cases of infection due to Candida fungus have increased globally due to increasing cases of HIV / AIDS infection. White Cambodia is one type of plant that has various properties as a medicinal plant. So far several studies related to the effectiveness of natural antifungi have been carried out on the leaves of white frangipani plants. The effectiveness of antifungi in other white frangipani plant organs such as flowers is still rarely reported. The purpose of this study was to determine the saponin compound content of white frangipani flowers (Plumeria acuminata) and the effectiveness of these compounds on the growth of Candida albicans. The method used in this study: identification of antifungal saponin compounds was carried out by foam testing. Antifungal effectiveness test of saponin compounds on the growth of Candida albicans was tested by the Kirby-Bauer method. Quantitative data of inhibition zone diameters formed in each treatment were analyzed using ANOVA (Analysis of Variance) level of 5%. ANOVA analysis results were significantly different (P <0.05) followed by Duncan's test to see differences between treatments. The results showed that white frangipani saponins (Plumeria acuminata) had antifungal activity on Candida albicans as indicated by the emergence of a 7.7 mm inhibition zone (medium category). Keyword: Candida albicans, Acacia auriculiformis, antifungal, saponin
Co-Authors A. A. Bawa Putra Dylla Hanggaeni Dwi Puspaningrum Dylla Hanggaeni Dyah Puspaningrum Eka Putri Suryantari I Gede Agus Handyka Kumala I Gst Ayu Ika Monika P I Gusti Ayu Putu Dian Anggraeni I Gusti Ayu Wita Kusumawati I Kade Fandy Rajendra Suta I Komang Tio Marta Bagusadewa I Made Gde Sudyadnyana Sandhika I Made Wisnu Adhi Putra Jois Kadek Andi Dwi Saputra Komang Try Adnyani Rahayu Luh Made Candrika Yati N. W. Bogoriani NI KADEK YUNITA SARI Ni Made Dwijayanti Ni Made Tia Erlinda Sukadewi Ni Putu Diantariani Ni Putu Widya Astuti Ni Wayan Rahayuni Nyoman Ayu Wiwin Yuliastini Pande Kadek Widiastuti Permatasari, Anak Agung Ayu Putri Rahmadi Prasetijo