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All Journal Jurnal Kesehatan Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Media Kesehatan Politeknik Kesehatan Makassar Jurnal Riset Kefarmasian Indonesia Jurnal farmasi UIN Alauddin Makassar Jurnal Buana Farma INDRA: Jurnal Pengabdian kepada Masyarakat Jurnal Multidisiplin Madani (MUDIMA) Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Katalisator Medical Sains : Jurnal Ilmiah Kefarmasian
Sri Wahyuningsih
Jurusan Farmasi, Fakultas Farmasi, Universitas Megarezky
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Public Health Social Sciences

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Journal : Jurnal Farmasi Galenika (Galenika Journal of Pharmacy)

 1 
Burns Wound Healing Activity of Extract Gel Formula of Lidah Buaya (Aloe vera) and Senggani Leaf (Melastoma polyanthum): Aktivitas Penyembuhan Luka Bakar Formula Gel Ekstrak Lidah Buaya (Aloe vera) dan Daun Senggani (Melastoma polyanthum) Sri Wahyuningsih; A. Suparlan Isya Syamsu; Nurhikma Awaluddin; Riki Andriawan
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 1 (2021): (March 2021)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i1.15251

Abstract

Aloe vera and senggani leaf can accelerate tissue regeneration, re-epithelialization, fibroblast stimulation, and collagen formation in the skin for burns wound healing. Burns wound can cause damage in the capillaries of the skin, then Aloe vera and senggani leaf were formulated into the gel formula for burns wound healing. The gel has the advantage of high water content; then it will hydrate the epidermis layer, increasing the penetration of the active substances. This study aims to formulate a gel of extract Aloe vera and senggani leaf (Melastoma polyanthum) and to evaluate the burns wound healing activity. The gel was formulated by composition of Aloe vera : senggani leaf with concentrations (0.5%: 1%); (0.5% : 3%); and (0.5% : 5%). Burns wound healing activity was observed by the diameter of the burn wound. The result showed that the gel with a concentration of (0.5%: 5%) gave a significance value of 0.692 (p >0.05) against positive control, then it was the formula that effective for burns wound healing.
Co-Authors A. Nur Ayu Lestari A. Suparlan Isya Syamsu Abdul Wahid Suleman Aliah, Ahmad Irsyad Andi Juaella Yustisi Chikita Inaku Farid, Nurfiddin Inda Andriani Inda sari Ivon Sensiana Ndaso Mike Arum Muhammad Asri Nielma Auliah Nurhikma Awaluddin Nurjannah Bachri Putri Indah Sari Rahmahsinar Amin Riki Andriawan Rizky Indah Pratiwi Safaruddin Salwi Salwi Widya Ariati