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All Journal e-GIGI Majalah Kedokteran Gigi Indonesia Dental Journal (Majalah Kedokteran Gigi) Jiko (Jurnal Informatika dan komputer)
Intan Ruspita
Department Of Prosthodontics Faculty Of Dentistry, Universitas Gadjah Mada
Computer Science & IT Dentistry

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Dealing with the high-risk potential of COVID-19 cross-infection in dental practice Heribertus Dedy Kusuma Yulianto; Nunuk Purwanti; Trianna Wahyu Utami; Anne Handrini Dewi; Dyah Listyarifah; Intan Ruspita; Asikin Nur; Heni Susilowati
Majalah Kedokteran Gigi Indonesia Vol 6, No 1 (2020): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.56588

Abstract

The World Health Organization reported that the SARS-CoV-2 virus has infected more than 5 million people around the world. Dental care providers and health care professionals need to be aware of the high-risk potential of crossinfection since the routes of virus transmission commonly happen through droplets and aerosols. This review aimed at collecting essential knowledge about the COVID-19 needed by dental practitioners. The review focused on the oral involvement in COVID-19, the role of oral transmission as the high-risk potential of cross-infection and recommended strategies to minimize the risk of cross-infection in dental practice. We searched all the published clinical features from PubMed, Google Scholar, Scopus and hand searched library online databases, from January 2015 until May 2020. Keywords used were “COVID-19”, “Dentistry”, “Dental protection”, “Cross-contamination”, “Aerosol and non aerosol”, and ”Povidone-iodine” with their combinations. We identified 52 articles to review after the initial selection with inclusion and exclusion criteria. Results showed use of topical applications of povidine-iodine and viricidal mouthwash could significantly reduce the high-risk of cross-infection from dentistry patients who are asymptomatic with COVID-19 infection. Further safeguards include suspending all non-emergency procedures temporarily and closely screening patients for symptoms which may be suspected to be COVID-19 infection.
The effect of 1,25-dihydroxyvitamin D3 on MSX2 gene expression during tooth and alveolar bone development Intan Ruspita
Dental Journal (Majalah Kedokteran Gigi) Vol. 48 No. 1 (2015): March 2015
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (344.588 KB) | DOI: 10.20473/j.djmkg.v48.i1.p43-47

Abstract

Background: 1,25-dihydroxyvitamin D3 has been proven to be able to control the formation and biomineralization of tissue through a regulatory gene. A previous research even showed that a cell responsible for the formation of the enamel (ameloblasts), dentin (odontoblasts) and bone (osteoblasts, osteoclasts) was the target of  1,25-dihydroxivitamin D3. Purpose: This research was aimed to determine the role of 1,25- dihydroxyvitamin D3 in vivo in the development of teeth and alveolar bone tissue by analyzing MSX2 gene expression as a gene marker responsible for the growth and development of enamel, dentin, tooth root and alveolar bone. Methods: Samples used for RT-PCR analysis were total RNA of insisivus teeth and alveolar bone derived from mice. RT-PCR analysis was conducted by using primer-specific gene, MSX2. Primer gene, GAPDH, was also used as an internal control. Five hundred nanograms of total RNA were used as a template for PCR. Semi quantitative results of PCR were quantified by using ImageJ software. Results: RT-PCR analysis showed that the expression level of MSX2 was enhanced in the samples of teeth and alveolar bone treated with 1,25 dihydroxyvitamin D3. The increasing of MSX2 expression significantly occurred in alveolar bone samples. Conclusion: It can be concluded that 1,25 dihydroxyvitamin D3 could enhance MSX2 expression as a marker of the development of teeth and alveolar bone tissue. Therefore, 1,25-D3 dihydroxyvitamin is expected to be used as an agent to help the regeneration of teeth and bone tissue.
SISTEM PAKAR PEMILIHAN OBAT UNTUK PASIEN GIGI DENGAN PENYAKIT SISTEMIK khanan khanan; Sri Kusumadewi; Intan Ruspita
JIKO (Jurnal Informatika dan Komputer) Vol 3, No 2 (2020)
Publisher : Journal Of Informatics and Computer

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/jiko.v3i2.1739

Abstract

Pasien yang datang ke dokter gigi tidak semua memiliki kondisi kesehatan umum yang baik, bebas dari penyakit sistemik dan konsumsi obat-obatan tertentu. Dokter gigi dihadapkan pada bermacam kondisi pasien yang berbeda sehingga diperlukan kehati-hatian dalam meresepkan obat untuk pasien, misalnya ketika terdapat kontraindikasi dari obat yang hendak diresepkan dengan kondisi sistemik pasien. Sistem pakar pemilihan obat untuk pasien penyakit gigi dan mulut dengan penyakit sistemik dapat menjadi solusi bagi masalah tersebut. Sistem pakar dapat memberikan saran obat-obatan yang aman diresepkan oleh dokter gigi sesuai kondisi sistemik pasien beserta informasi terkait obat. Basis pengetahuan diperoleh dari literatur dan wawancara pakar yang direpresentasikan dalam tabel keputusan. Teknik pelacakan basis pengetahuan dengan menggunakan metode backward chaining. Pengujian blackbox dilakukan untuk menguji bahwa aplikasi dapat berfungsi sebagaimana yang dikehendaki dan bebas error. Pengujian validitas sistem pakar dilakukan dengan membandingkan hasil pemilihan obat dari sistem pakar terhadap 10 contoh kasus diagnosis kedokteran gigi dengan jawaban yang diberikan oleh pakar. Pengujian validitas menunjukkan bahwa sistem pakar memiliki nilai keakuratan 75%. Sistem pakar dapat melakukan proses penelusuran fakta dengan baik sesuai kondisi pasien, membantu dokter gigi dalam menentukan obat yang sesuai dengan kondisi sistemik pasien, dan memberikan informasi terkait obat tersebut.
Pengaruh Lama Perendaman Basis Gigi Tiruan Resin Asetal dalam Larutan Hidrogen Peroksida 3% sebagai Denture Cleanser terhadap Perlekatan Candida albicans Yoanne Imanuella; Titik Ismiyati; Intan Ruspita
e-GiGi Vol. 11 No. 1 (2023): e-GiGi
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/eg.v11i1.44387

Abstract

Abstract: Denture cleanser could control biofilm formation, however, it could also cause noticable changes to the surface denture base material, such as an increase in surface roughness and discoloration. This study aimed to evaluate the effect of immersion time of acetal resin denture base in H2O2 3% as denture cleanser on the attachment of Candida albicans. Samples were made of acetal resin in the form of disc with a diameter of 5 mm and height of 2 mm as many as 24 pieces which were divided into four groups as follows: six discs without treatment, six discs were immersed in H2O2 3% for 3.5 hours, six discs were immersed for 14 hours, and six discs were immersed for 42 hours. The number of Candida albicans colonies was calculated in units of CFU/ml. The results showed that there was an effect of H2O2 3% immersion time on the adhesion of Candida albicans in all immersion groups after being compared with the control group. The highest number of Candida albicans attachment was found on the group with 42 hours immersion time. In conclusion, the immersion time of acetal resin denture base in H2O2 3% for 3,5 hours had the lowest effect on the adhesion of Candida albicans compared to the duration of immersion for 14 and 42 hours. Keywords: acetal resin; denture cleanser; hydrogen peroxide 3%; Candida albicans Abstrak: Denture cleanser dapat mengontrol pembentukan biofilm, tetapi juga mengakibatkan perubahan yang terlihat pada permukaan basis gigi tiruan seperti peningkatan kekasaran permukaan dan perubahan warna. Penelitian ini bertujuan untuk mengevaluasi pengaruh lama perendaman basis gigi tiruan resin asetal dalam H2O2 3% sebagai denture cleanser terhadap perlekatan Candida albicans. Sampel dibuat dari cakram resin asetal dengan diameter 5 mm dan tinggi 2 mm sebanyak 24 buah yang dibagi menjadi empat kelompok yaitu, 6 cakram tanpa perlakuan, 6 cakram direndam dalam H2O2 3% selama 3,5 jam, 6 cakram direndam selama 14 jam, dan 6 cakram direndam selama 42 jam. Jumlah Candida albicans dihitung dalam satuan CFU/ml unit. Hasil penelitian memperlihatkan bahwa terdapat pengaruh lama perendaman dalam H2O2 3% terhadap perlekatan Candida albicans pada semua kelompok setelah dibandingkan dengan kelompok kontrol. Jumlah Candida albicans tertinggi ditemukan pada kelompok dengan lama perendaman selama 42 jam. Simpulan penelitian ini ialah lama perendaman basis gigi tiruan resin asetal dalam H2O2 3% selama 3,5 jam memiliki pengaruh paling rendah terhadap perlekatan Candida albicans dibandingkan dengan lama perendaman 14 jam dan 42 jam. Kata kunci: resin asetal; denture cleanser; hidrogen peroksida 3%; Candida albicans
Co-Authors Anne Handrini Dewi Asikin Nur Dyah Listyarifah Heni Susilowati Heribertus Dedy Kusuma Yulianto khanan khanan Nunuk Purwanti Sri Kusumadewi Titik Ismiyati Trianna Wahyu Utami Yoanne Imanuella