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OVIPOTIONAL AND PREFERENCIAL TEST OF Bactrocera albistrigata ON GUAVA EXTRACTS Nadia Farida; Agus Susanto
Jurnal Penelitian Saintek Vol 23, No 1 (2018): April 2018
Publisher : Institute of Research and Community Services, Universitas Negeri Yogyakarta

Bactrocera albistrigata commonly attacks rose apple and guava. It is capable of causing up to 100% damage on guava. The study was aimed at determining the most preffered fruit extract by B. albistrigata. The research was conducted at Rearing Pest Laboratory of Faculty of Agriculture Universitas Padjadjaran in Jatinangor, Sumedang. The experiment used Completely Randomized Design consisting of three treatments and four replications. The treatments were conducted on red guava extract, rose apple extract, and guava essences by the used of choice and no choice tests. The result shows that in the red guava extract has the highest number of eggs of B. albistrigata compared to that in rose apple extract and guava essences.UJI PREFERENSI DAN OVIPOSISI Bactrocera albistrigata PADA EKSTRAK JAMBUBactrocera albistrigata lebih sering menyerang tanaman jambu biji dan jambu air. Kehilangan hasil pada tanaman jambu biji yang disebabkan oleh serangan lalat buah ini dapat mencapai 100%. Penelitian ini bertujuan untuk mengetahui ekstrak buah yang paling disukai lalat buah B. albistrigata. Penelitian dilaksanakan di Laboratorium Perbanyakan Serangga, Departemen Hama, dan Penyakit Tumbuhan, Fakultas Pertanian, Universitas Padjadjaran, Jatiangor, Sumedang. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) yang terdiri atas 3 perlakuan dengan 4 ulangan. Perlakuan terdiri atas ekstrak jambu biji merah, ekstrak jambu air, dan esens jambu. Dengan menggunakan choice dan no choice test, hasil penelitian menunjukkan bahwa dalam ekstrak jambu biji merah terdapat jumlah telur B. albistrigata yang lebih tinggi dari ekstrak jambu air dan esens jambu.

PENGARUH UKURAN PARTIKEL KAOLIN TERHADAP MORTALITAS, PERTUMBUHAN, DAN PERKEMBANGAN ULAT GRAYAK JAGUNG Widia Herhayulika; Yusup Hidayat; Agus Susanto
Jurnal Penelitian Saintek Vol 26, No 2 (2021)
Publisher : Institute of Research and Community Services, Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/jps.v26i2.42983

Penelitian ini bertujuan untuk mengetahui pengaruh ukuran partikel mineral kaolin terhadap mortalitas, pertumbuhan dan perkembangan larva S. frugiperda. Metode penelitian menggunakan Rancangan Acak Kelompok (RAK) dengan 7 perlakuan dan 4 ulangan. Perlakuan terdiri atas formulasi mineral kaolin konsentrasi 4% dengan ukuran saringan 100, 200, 300, 400, dan 500 mesh; kontrol air; dan kontrol wetting agent+dispersant agent. Hasil penelitian menunjukkan bahwa ukuran partikel mineral kaolin berpengaruh terhadap mortalitas, lama perkembangan, berat pupa, dan kemunculan imago S. frugiperda. Mineral kaolin ukuran partikel 500 mesh menghasilkan mortalitas larva S. frugiperda (28,75%) yang berbeda nyata dengan kontrol (0,00%) pada 48 jam setelah perlakuan. Sementara itu, pada pengamatan 23 hari setelah perlakuan, semua ukuran partikel mineral kaolin yang diuji menyebabkan mortalitas larva S. frugiperda sebesar 31,25-51,25%; yang berbeda nyata dengan kontrol (0,00%). Perlakuan mineral kaolin 500 mesh menghasilkan total perkembangan larva dan pupa yang terlama yaitu 22,25 hari; berat pupa paling rendah yaitu 0,1506 g serta kemunculan imago normal yang terendah yaitu 8,00 ekor (dari 20 larva yang diberi perlakuan). Dengan demikian, mineral kaolin pada ukuran 500 mesh dapat diaplikan sebagai bahan pengendali hama S. frugiperda.EFFECT OF KAOLIN PARTICLE SIZE ON MORTALITY, GROWTH, AND DEVELOPMENT OF FALL ARMY WORMThis study aimed to determine the effect of kaolin mineral particle sizes on mortality, growth and develpoment of S. frugiperda larvae. The research method used a Randomized Block Design (RBD) with 7 treatments and 4 replications. The treatments consisted of kaolin mineral formulation concentration of 4% with the particle sizes of 100, 200, 300, 400 dan 500 mesh.Two controls were used namely water and wetting agent+dispersant agent. The results showed that the particle size of the kaolin mineral had an effect on mortality, developmental time, pupal weight and emergence of S. frugiperda adult. Kaolin mineral with a particle size of 500 mesh resulted in mortality of S. frugiperda larvae (28,75%) which was significantly different from the control (0,00%) at 48 hours after treatment. Meanwhile, on observation 23 days after treatment, all tested kaolin mineral particle sizes caused the mortality of S. frugiperda larvae of 31,25-51,25%, which was significantly different from the mortality in control (0,00%). The 500 mesh kaolin mineral treatment resulted in the longest total larval and pupal development (22,25 days), the lowest pupal weight (0,1506 g) and the lowest normal adult emergence (8 of 20 treathed larvae). Thus, the kaolin mineral at a size of 500 mesh can be applied as a pest control material for S. frugiperda.

Perbedaan kadar kalium dan natrium pada saliva pasien periodontitis kronis dan tanpa periodontitis kronisDifferences in potassium and sodium levels in the saliva of patients with and without chronic periodontitis Muhammad Haikal Mahardhika; Ina Hendiani; Agus Susanto
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 28, No 3 (2016): Desember
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Pendahuluan: Periodontitis kronis menyebabkan perbedaan kadar ion kalium dan natrium pada saliva karena terjadinya perpindahan ion- ion tersebut dari cairan intraseluler dan ekstraseluler sel dan jaringan yang mengalami peradangan menuju saliva. Tujuan penelitian ini bertujuan untuk mengetahui perbedaan kadar kalium dan natrium pada saliva pasien periodontitis kronis dan pasien tanpa periodontitis kronis. Metode: Penelitian deskriptif analitik, subjek penelitian sebanyak 30 pasien, terdiri dari 15 pasien periodontitis kronis dan 15 pasien tanpa periodontitis kronis. Pengukuran poket periodontal dan pengambilan saliva menggunakan spitting method serta pengukuran kadar kalium dan natrium saliva dalam satuan mmol/L menggunakan spektrofotometer AAS. Data diuji secara statistik menggunakan uji t independent sample test. Hasil: rata-rata kadar kalium dan natrium pada pasien periodontitis kronis (18,22 mmol/L dan 9,92 mmol/L), sedangkan pada pasien tanpa periodontitis kronis (16,54 mmol/L dan 6,95 mmol/L). Tidak terdapat perbedaan signifikan kadar kalium saliva pasien periodontitis kronis dan pasien tanpa periodontitis kronis (p=0,351), dan terdapat perbedaan signifikan kadar natrium pada saliva pasien periodontitis kronis dan pasien tanpa periodontitis kronis (p=0,004). Simpulan: Kadar natrium pada saliva pasien periodontitis kronis lebih tinggi dibandingkan pasien tanpa periodontitis.Kata kunci: Kalium, natrium, periodontitis kronis, saliva. ABSTRACTIntroduction: Chronic periodontitis causes differences in potassium and sodium ion levels in saliva due to the transfer of these ions from intracellular and extracellular fluid cells and tissues that experience inflammation into saliva. The aim of this study was to determine differences in potassium and sodium levels in the saliva of chronic periodontitis patients and patients without chronic periodontitis. Methods: A descriptive analytic study conducted towards 30 patients, consisting of 15 chronic periodontitis patients and 15 patients without chronic periodontitis. Measurement of periodontal pockets and saliva retrieval using spitting method and measurement of salivary potassium and sodium levels in mmol/L using AAS spectrophotometer. Data were statistically tested using independent sample test t test. Results: The average potassium and sodium levels in chronic periodontitis patients (18.22 mmol/L and 9.92 mmol/L), whereas in patients without chronic periodontitis (16.54 mmol/L and 6.95 mmol/L). There were no significant differences in potassium saliva levels of chronic periodontitis patients and patients without chronic periodontitis (p = 0.351), and there were significant differences in sodium levels in the saliva of chronic periodontitis patients and patients without chronic periodontitis (p = 0.004). Conclusion: Sodium levels in the saliva of chronic periodontitis patients are higher than patients without periodontitis.Keywords: Potassium, sodium, chronic periodontitis, saliva.

Efek pasta gigi kalsium karbonat dan hydrated silica terhadap pewarnaan gigi perokokThe effect of calcium carbonate and hydrated silica toothpaste on the smoker’s teeth colouration Agus Susanto; Ina Hendiani; Mutiara Siti Fatimah
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 30, No 1 (2018): April
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Pendahuluan: Pewarnaan pada gigi dalam rongga mulut akibat merokok sering kali menyebabkan terjadinya perubahan warna pada gigi, dan menyebabkan perokok merasa tidak puas dengan penampilan gigi mereka. Penelitian ini bertujuan untuk menilai perbedaan efek pasta gigi yang mengandung kalsium karbonat dan hydrated silica terhadap penurunan pewarnaan gigi perokok. Metode: Jenis penelitian adalah eksperimental semu dengan metode pre and post test design. Sampel sebanyak 30 orang mahasiswa Fakultas Teknik Geologi Unpad. Kelompok pertama melakukan penyikatan gigi dengan kalsium karbonat dan kelompok kedua dengan hydrated sillica. Pewarnaan diukur dengan indeks pewarnaan Lobene yang terdiri dari nilai intensitas, area, dan gabungan, selain itu dilakukan pengukuran dengan menggunakan acuan intensitas pewarnaan Pepsodent™. Data dianalisis dengan uji t, uji Wilcoxon, dan uji Mann-Whitney. Hasil: Hasil uji menunjukan kalsium karbonat menurunkan pewarnaan gigi perokok dilihat dari seluruh pengukuran, hydrated silica menurunkan pewarnaan gigi perokok dilihat dari pengukuran intensitas Pepsodent™, area Lobene, dan gabungan Lobene, serta terdapat perbedaan penurunan pewarnaan gigi menurut pengukuran intensitas Pepsodent™, area Lobene, dan gabungan Lobene pada kelompok kalsium karbonat dibandingkan dengan kelompok hydrated silica. Simpulan: Penurunan pewarnaan gigi dengan menggunakan pasta gigi yang mengandung kalsium karbonat lebih besar dibandingkan dengan pasta gigi yang mengandung hydrated silica.Kata kunci: Calcium carbonate, hydrated silica, pasta gigi, perokok, pewarnaan gigi. ABSTRACTIntroduction: Tooth discolouration due to smoking often causes stains, tooth colour changes, and makes smokers dissatisfied with their tooth appearance. The purpose of the research was to assess the differences between toothpaste contained calcium carbonate and hydrated silica in reducing discolouration of the smoker’s teeth. Methods: A quasi-experimental was performed with a pre and post test design method. As much as 30 students from the Faculty of Geological Engineering served as samples. The first group conducted the tooth brushing with calcium carbonate and the second group with hydrated silica. Discolouration was measured with Lobene Discolouration Index, which values the intensity, area, and combination. Furthermore, other measurements also performed using the Pepsodent™ discolouration-intensity index. All data were analysed using the t-test, Wilcoxon test, and Mann-Whitney test. Result: The results showed that calcium carbonate toothpaste reduced the smokers’ tooth discolouration observed using all measurement, while hydrated silica toothpaste reduced the smoker’s teeth discolouration only when observed using Pepsodent™ intensity, Lobene area, and combination measurements. There was also a different reduction in tooth discolouration according to Pepsodent™ intensity, Lobene area, and combination measurement in the group of calcium carbonate toothpaste compared to hydrated silica toothpaste. Conclusion: Calcium carbonate toothpaste was found to be better in reducing the smoker’s tooth discolouration compared with hydrated silica toothpaste.Keywords: Calcium carbonate, hydrated silica, toothpaste, smokers, tooth discolouration.

Perbandingan antara metode menyikat gigi Bass dan Charter terhadap pengendalian plak pada pemakai ortodonti cekatComparison between Bass and Charter toothbrushing methods for plaque control of fixed orthodontic users Amelia Maharani; Yanti Rusyanti; Agus Susanto
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 30, No 3 (2018): Desember
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Pendahuluan: Kebersihan mulut merupakan salah satu masalah pada pemakai ortodonti cekat karena gigi geligi lebih sulit dibersihkan, sehingga dapat meningkatkan akumulasi plak. Tujuan penelitian ini adalah untuk menganalisis dengan membandingkan metode menyikat gigi Bass dan Charter terhadap pengendalian plak pada pemakai ortodonti cekat. Metode: Jenis penelitian eksperimental dilakukan pada 32 orang mahasiswa Fakultas Kedokteran Gigi Universitas Padjadjaran dengan metode single blind. Data dianalisis dengan uji two-way repeated measures ANOVA. Hasil: Tidak terdapat perbedaan yang signifikan antara metode menyikat gigi Bass dan Charter (p>0,05), tetapi nilai plak menurun secara signifikan setelah menyikat gigi pada kedua kelompok (p<0,05). terdapat perbedaaan plak yang signifikan pada daerah servikal antara kedua metode (p<0,05). Simpulan: Metode Charter lebih efektif dalam menurunkan plak di daerah servikal, tetapi secara keseluruhan metode menyikat gigi Bass dan Charter memiliki efektivitas yang sama terhadap pengendalian plak pada pemakai ortodonti cekat.Kata kunci: Metode Bass, metode Charter, plak, ortodonti cekat. ABSTRACTIntroduction: Oral hygiene is one of the problems faced by fixed orthodontic users because it creates difficulties in cleaning the teeth thus increasing plaque accumulation. The purpose of this study was to analyse the difference between Bass and Charter toothbrushing methods for plaque control in fixed orthodontic users. Methods: This research was an experimental conducted towards as much as 32 students of the Faculty of Dentistry Universitas Padjadjaran with a single-blind method. All data were analysed by the two-way repeated measures ANOVA. Result: There were no significant differences between Bass and Charter tooth brushing methods (p > 0.05), but the plaque value decreased significantly after toothbrushing in both groups (p < 0.05). There were significant differences in the plaque in the cervical area between the two methods (p < 0.05). Conclusion: The Charter toothbrushing methods was proven to be more effective in reducing plaque in the cervical area, however, both Bass and Charter toothbrushing method had the same effectiveness on plaque control of fixed orthodontic users.Keywords: Fixed orthodontic appliances, plaque, Bass toothbrushing method, Charter toothbrushing method.

Perbandingan efektifitas pasta gigi yang mengandung sodium bikarbonat dan sodium monofluorofosfat terhadap plak dan gingivitisComparison of the effectiveness between toothpaste contained sodium bicarbonate and sodium monofluorophosphate against plaque and gingivitis Beta Duwisda; Nunung Rusminah; Agus Susanto
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 28, No 3 (2016): Desember
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Pendahuluan: Sodium bikarbonat dan sodium monofluorofosfat merupakan bahan aktif yang digunakan dalam pasta gigi dan memiliki fungsi tertentu. Penelitian ini dilakukan dengan tujuan untuk membandingkan efektifitas kedua bahan tersebut dalam pasta gigi terhadap plak dan gingivitis. Jenis penelitian ini deskriptif dengan desain pre dan post-test. Metode: Sampel berjumlah 30 orang dibagi menjadi dua kelompok, masing-masing mendapat perlakuan penyikatan gigi dengan pasta gigi yang mengandung sodium bikarbonat dan pasta gigi yang mengandung sodium monofluorofosfat. Subjek diminta menyikat gigi dua kali sehari selama 14 hari. Penilaian menggunakan Indeks Plak menurut Sillness dan Loe dan Indeks Gingiva menurut Loe dan Sillness. Data dianalisis dengan uji t dan uji Mann-Whitney. Hasil: Pasta gigi yang mengandung sodium bikarbonat maupun sodium monofluorofosfat tidak memiliki perbedaan yang signifikan dalam menurunkan indeks plak dengan nilai p-value 0,983 (p> 0,05). Kedua pasta gigi memiliki efektifitas dalam menurunkan indeks gingiva dengan nilai p-value 0,044 (p<0,05). Pasta gigi yang mengandung sodium bikarbonat lebih efektif dalam menurunkan indeks gingiva dilihat dari penurunan rata- ratanya. Simpulan: Kedua pasta gigi tidak efektif menurunkan plak namun efektif dalam menurunkan gingivitis dimana pasta gigi yang mengandung sodium bikarbonat lebih efektif menurunkan gingivitis dibandingkan dengan sodium monofluorofosfat.Kata kunci: Gingivitis, pasta gigi, plak, sodium bikarbonat, sodium monofluorofosfat. ABSTRACTIntroduction: Sodium bicarbonate and sodium monofluorophosphate are active ingredients used in toothpaste and have certain functions. This study was conducted with the aim to compare the effectiveness of the two ingredients in toothpaste against plaque and gingivitis. This type of research is descriptive with pre and post-test design. Methods: A sample of 30 people was divided into two groups, each of which was treated with toothpaste with toothpaste containing sodium bicarbonate and toothpaste containing sodium monofluorophosphate. Subjects were asked to brush their teeth twice a day for 14 days. Assessment uses the Plaque Index according to Sillness and Loe and the Gingiva Index according to Loe and Sillness. Data were analyzed by t-test and Mann-Whitney test. Results: Toothpaste containing sodium bicarbonate and sodium monofluorophosphate did not have a significant difference in reducing plaque index with p-value of 0.983 (p > 0.05). Both toothpastes have effectiveness in lowering the gingival index with a p-value of 0.044 (p < 0.05). Toothpaste containing sodium bicarbonate is more effective in lowering the gingival index as seen from the decrease in average. Conclusion: Both toothpastes are not effective in reducing plaque but are effective in reducing gingivitis where toothpaste containing sodium bicarbonate is more effective in reducing gingivitis compared to sodium monofluorophosphate.Keywords: Gingivitis, toothpaste, plaque, sodium bicarbonate, sodium monofluorophosphate.

Prevalence and characteristics of aggressive periodontitis Diatri Nariratih; Janti Rusjanti; Agus Susanto
Padjadjaran Journal of Dentistry Vol 23, No 2 (2011): July 2011
Publisher : Faculty of Dentistry Universitas Padjadjaran

Aggressive Periodontitis is one of periodontal disease that generally affects individuals less than 30 years old, with a rapid attachment loss and alveolar bone destruction. Special features of the disease are affected incisors and first molars with symmetrical bilateral destruction. The purpose of this study was to determine the prevalence and characteristics of Aggressive Periodontitis at Student Clinics, Faculty of Dentistry Padjadjaran University on May to July 2010. Based on accidentally sampling, 415 new patients at Dental and Oral Hospital, Faculty of Dentistry Padjadjaran University and Dental and Oral Polyclinic at RSUP dr. Hasan Sadikin Bandung participated in this study. Each subject filled out the questionnaire and did a clinical examination. Patients with attachment loss ≥ 4 mm were referred for radiographic and microbiologic examination to support the diagnosis. The results showed that there were 13 patients who have the diagnostic criteria of Aggressive Periodontitis. Nine patients were diagnosed as Localized Aggressive Periodontitis, and 4 patients as Generalized Aggressive Periodontitis. It is concluded that the prevalence of Aggressive Periodontitis was 3.13%, and indicated low prevalence. Characteristics of Localized Aggressive Periodontitis patients were female in 20-29 age range, whereas characteristics of Generalized Aggressive Periodontitis patients were male in 30-39 age range.

The effectiveness of mangosteen rind extract as additional therapy on chronic periodontitis (Clinical trials) Ina Hendiani; Dede Hadidjah; Agus Susanto; Indra Mustika Setia Pribadi
Padjadjaran Journal of Dentistry Vol 29, No 1 (2017): March 2017
Publisher : Faculty of Dentistry Universitas Padjadjaran

Introduction: Periodontitis is an inflammatory disease that attacks the periodontal tissue comprises the gingiva, periodontal ligament, cementum and alveolar bone caused mainly by plaque bacteriophage or other specific dominant type of bacteria. The purpose of this study was to determine the therapeutic effect of clinical application of mangosteen peel extract gel as adjunctive therapy scaling and root planing in patients with chronic periodontitis. This research was expected to developed new treatment in the field of dentistry, particularly in periodontics, which can be used as supporting material for the treatment of chronic periodontitis. Methods: Quasi-experimental research, split mouth, with as many as 14 chronic periodontitis patients. Mangosteen rind was prepared to be formed into extract gel, dried at room temperature, then the dried samples were macerated by using ethanol, then evaporated and decanted for 3 days until obtained condensed extract. The samples were patients with chronic periodontitis in at least 2 teeth with pockets ≥ 5 mm. Clinical parameters of pocket depth, gingival bleeding, and clinical epithelial attachment level were measured at baseline and 1 month after treatment. Analysis of data using the t-test. Results: The comparison of average gap ratio of pockets depth, gingival index, gingival bleeding and epithelium attachment levels, before and after treatment showed significant differences, such as in the test and control sides. Conclusion: The mangosteen rind gel as adjunctive therapy for scaling and root planing is able to reduce pockets depth, gingival index, and gingival bleeding, and improve clinical epithelial attachment.

Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of mangosteen (Garcinia mangostana Linn.) rind extract against Aggregatibacter actinomycetemcomitans Ina Hendiani; Agus Susanto; Dyah Nindita Carolina; Rahmat Ibrahim; Felisha Febriane Balafif
Padjadjaran Journal of Dentistry Vol 32, No 2 (2020): July 2020
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol32no2.27366

Introduction: The main contents of mangosteen (Garcinia mangostana Linn.) is xanthone with antibacterial activity. Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) was a gram-negative, facultative anaerobic bacillus that causes periodontal diseases such as localised aggressive periodontitis (LAP). Mangosteen rind extract could inhibit the growth of Porphyromonas gingivalis and A. actinomycetemcomitans. This study was aimed to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of mangosteen rind extract against A. actinomycetemcomitans. Methods: This study was an experimental and in-vitro study of antimicrobial properties of mangosteen (Garcinia mangostana Linn.).The extract of mangosteen was made by the maceration method using 70% ethanol solvent. A. actinomycetemcomitans (ATCC 43718) obtained from Laboratorium of Microbiology Airlangga University Surabaya. This study used a microdilution method and analysed using the Enzyme Linked Immune Sorbent Assay (ELISA). The determination of the MIC was measured using the formula for cell inhibition percentage. Three concentrations higher than the MIC standard were cultured on the Mueller Hinton agar. The lowest concentration on agar which was not found any growth of the bacterial colonies was determined as the MBC. Results: The results of this study indicated that the MIC and MBC of mangosteen rind extract against A. actinomycetemcomitans were 195.3 ppm and 1562.5 ppm, respectively. Conclusion: Mangosteen rind extract can inhibit and bactericide the growth of A. actinomycetemcomitans.

Inhibitory and bactericidal power of mangosteen rind extract towards Porphyromonas Gingivalis and Actinobacillus Actinomycetemcomitans (Laboratory test) Ina Hendiani; Dede Hadidjah; Agus Susanto; Indra Mustika SP
Padjadjaran Journal of Dentistry Vol 28, No 2 (2016): July 2016
Publisher : Faculty of Dentistry Universitas Padjadjaran

Introduction: The bacteria that cause the occurrence of pathogens of periodontal disease are gram negative anaerobes. These bacteria include Pophyromonas Gingivalis and Actinobacillus Actinomycetemcomitans. Mangosteen skin extract is known to have anti-inflammatory, anti microbial, and anti oxidant properties. The extract of the mangosteen peel is altered in gel preparation in order to streamline its clinical application in periodontal disease. The purpose of this study was to examine the antibacterial power of the ginger mangosteen tree extract gel against Pophyromonas gingivalis and Actinobacillus Actinomycetemcomitans (Aggregatibacter Actinomycetemcomitans). Methods: This research was conducted by experimental laboratory. Mangosteen fruit extract gel with concentration of 100%, 50%, 25%, 12,5%, 6,25%, 3,125% and 0,78% were tested against Pophyromonas Gingivalis and Aggregatibacter Actinomycetemcomitans with agar diffusion method. Results: The results of this study indicate that for Actinobacilus Aggregatibacter bacteria minimal inhibitory concentration at a concentration of 6.25% with a diameter of 13,5mm inhibition. Minimal bactericidal concentration at 12,5% concentration with 14,7mm inhibitory diameter. In the test of Pophyromonas Gingivalis bacteria, minimal inhibitory concentrations were obtained at a concentration of 1.56% and a minimum bactericidal concentration was obtained at a concentration of 3.125%. Conclusion: The conclusion that mangosteen peel skin gel extract can inhibit bacterial growth and is bactericidal against Pophyromonas Gingivalis and Actinobacillus Actinomycetemcomitans (Aggregatibacter Actinomycetecomitans).

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