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Journal : Open Access Indonesian Journal of Medical Reviews

The Role of Cell Membranes in Cell Traffic Rara Inggarsih; Ella Amalia; Septi Purnamasari
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 6 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i6.168

Abstract

The cell membrane plays an important role in cell traffic because it functions to secrete various molecules. The selective transport system allows the movement of molecules into or out of the cell compartment. By controlling the movement of substances from one compartment to another, membranes exert a strong influence on metabolic pathways. Cell membranes are composed of proteins and lipids with a very important function in maintaining the rhythm of circulation and cell transport. In addition, the cell membrane also plays a role in maintaining the integrity and relationship, and communication of cells.
The Role of Natural Physical, Mechanical, and Biochemical Barriers as Innate Immunity: A Narrative Literature Review Septi Purnamasari; Rachmat Hidayat
Open Access Indonesian Journal of Medical Reviews Vol. 3 No. 2 (2023): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v3i2.299

Abstract

The specialized epithelial outer layer, including the skin and mucosal surfaces, is relatively resistant to most environmental hazards and resistant to infection by disease-causing microorganisms. This literature review aimed to describe the role of natural physical, mechanical, and biochemical barriers in innate immunity. The physical barrier that protects against damage and infection consists of closely related epithelial cells, including the skin and the sheet membranes that line the digestive tract, genitourinary, and breathing. The epithelial surface also provides a biochemical barrier by synthesizing and secreting substances intended to trap or destroy microorganisms (chemicals derived from the epithelium). Mucus, sweat, saliva, tears, and earwax are examples of biochemical secretions that can trap and kill potential disease-causing microorganisms. Microorganisms in the microbiome do not usually cause disease, although some are opportunistic in that they can cause disease if the integrity of the body surface is compromised or the individual's immune or inflammatory systems are damaged. In conclusion, natural barriers include physical, mechanical, and biochemical on the surface of the body and are present from birth to prevent damage by substances in the environment and prevent infection by pathogenic microorganisms.