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All Journal JBIO: jurnal biosains (the journal of biosciences) CHEMPUBLISH JOURNAL JI-KES (Jurnal Ilmu Kesehatan) Walisongo Journal of Chemistry Jurnal Kreativitas PKM Pharmaceutical Journal of Indonesia Jurnal ABDINUS : Jurnal Pengabdian Nusantara Bubungan Tinggi: Jurnal Pengabdian Masyarakat Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal EduHealth Jurnal Sains dan Kesehatan Jurnal Pengabdian Masyarakat (JPM) Pinang Masak Prosiding Seminar Nasional Pengabdian kepada Masyarakat (SINAPMAS)
Afidatul Muadifah
Department Of Pharmacy, STIKES Karya Putra Bangsa, Tulungagung 66291, East Java
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : CHEMPUBLISH JOURNAL

 1 
Studi aktivitas ekstrak etanol dan sediaan gel daun melinjo (Gnetum gnemon L) sebagai antibakteri terhadap Staphylococcus Aureus Indra Lasmana Tarigan; Afidatul Muadifah; Helda Wika Amini; Tri Kurnia Astutik
CHEMPUBLISH JOURNAL Vol. 4 No. 2 (2019): Chempublish Journal
Publisher : Universitas Jambi, Fakultas Sains dan Teknologi, Program Studi Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v4i2.7631

Abstract

Melinjo (Genus Gnetii gnemonii Folium) merupakan spesies tanaman yang berasal dari semenanjung Malaysia dan Indonesia, diketahui memiliki senyawa bioaktif yang dapat dimanfaatkan dibidang kesehatan. Tujuan penelitian ini ini adalah untuk menganalisis profil senyawa bioaktif daun melinjo (Gnetii gnemonii Folium) yang memiliki fungsi sebagai antimikroba dengan menghambat pertumbuhan bakteri Staphylococcus aureus serta memformulasi gel dari ekstrak daun melinjo. Ekstrak daun melinjo dibuat dengan metode maserasi menggunakan pelarut etanol 70%, 3 hari. Analisis profil senyawa bioaktif daun melinjo menggunakan skrining fitokimia dan pengujian aktivitas antibakteri dilakukan menggunakan metode difusi cakram Kirby-Bauer terhadap Staphylococcus aureus. Konsentrasi ekstrak etanol daun melinjo yang digunakan interval konsentrasi 50%-80%. Ekstrak dengan konsentrasi optimum diformulasikan dalam bentuk gel dan dilakukan evaluasi mutu fisik sediaan gel meliputi organoleptis, uji homogenitas, uji pH, uji daya lekat dan uji daya sebar selama 28 hari. Hasil analisis menunjukkan senyawa bioaktif daun melinjo meliputi Tanin, Saponin, Alkaloid, Flavonoid, dan Triterpenoid. Ekstrak 80% daun melinjo memberikan efek antibakteri dengan zona hambat terbesar 13,08mm. Gel dari ekstrak daun melinjo 80% memberikan efek antibakteri dengan kategori kuat terhadap bakteri Staphylococcus aureus dengan diameter zona hambat sebesar 16,91mm.
AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK DAUN SIRIH DAN BELIMBING WULUH DENGAN METODE HIDROEKSTRAKSI Dara Tilarso; Afidatul Muadifah; Windu Handaru; Putri Indah Pratiwi; Mursyidah Lathifatul Khusna
CHEMPUBLISH JOURNAL Vol. 6 No. 2 (2021): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Antibacterial substances are substances that can inhibit the growth of bacteria by interfering with the metabolism of harmful microbes. Plants that have antibacterial activity include star fruit (Averrhoa bilimbi L.) and betel leaf (Piper betle). The purpose of this study was to determine the antibacterial activity of the combination of star fruit extract (Averrhoa bilimbi L.) and betel leaf (Piper betle) against Escherichia coli and Staphylococcus aureus bacteria. This research was conducted using the hydro extraction method at temperatures of 40,50,60, and 90°C and activity testing using the disc diffusion method with extract concentrations of 0, 10, 20, 30, 40, 50, 60, 70, 80, 90, and 100 %. The results showed that the combination had optimum inhibitory activity at 50° with an inhibition diameter of 19.75 mm for Staphylococcus aureus and 11.75 mm for Escherichia coli.
Calcium Reduction Using Variations of Thickness and Retention Time of Cocoa Shell Activated Carbon Afidatul Muadifah; Arif Santoso; Khoirul Ngibad; Rahma Diyan Martha; Siti Nurriyatul Kholifah
CHEMPUBLISH JOURNAL Vol. 7 No. 1 (2023): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v7i1.24768

Abstract

High levels of hardness can lead to increased cases of kidney stones. Hardness levels can be reduced by using activated carbon from the cocoa rind as an adsorbent. The purpose of this research was to determine the variation of activated carbon thickness and optimum retention time in reducing the calcium content of dug well water, to determine the percent decrease in calcium ion levels at the optimum variation, and to determine the significance of the difference in the decreased in calcium levels between the treatment groups. The research method used the principle of adsorption of activated carbon from cocoa shells to calcium ions, which are activated by KOH. There were ten treatment samples with different variations of activated carbon thickness and retention time. The results showed that the thickness of activated carbon of 60 cm with a retention time of 50 minutes had the optimum ability to reduce the calcium content of dug well water. The percentage decrease in calcium levels reached 89,041 % with a decreased concentration of 234 ppm. The result of the statistical test showed a significance value of 0,05. The conclusion of the research is that activated carbon of cocoa shells can reduce calcium levels to the levels of soft water hardness, with variations in activated carbon thickness and retention time having a significant effect.
Co-Authors Algafari Bakti Manggara, Algafari Bakti Alvi Zahrotun Nisak Amalia Putri Eka Ana Amalia Arif Santoso Ary Kristijono Ary Kristijono Choirul Huda Choirul Huda Cindy Melia Kartika Dara Pranidya Tilarso Dara Pranidya Tilarso Dara Tilarso Dhanang Prawira Nugraha Ema Krismawar Sari Fatimah Fatimah Helda Wika Amini ika Rachutami Indra Lasmana Tarigan Intan Fitria Kartika Arum Wardani Kartika Arum Wardani Khoirul Ngibad Khoirul Ngibad Khoirul Ngibad Khoirul Ngibad Millenia Ramadhani Mursyidah Lathifatul Khusna Nabila Puteri Salsabela Nabila Putri Salsabila Nindita Clourisa Clourisa Amaris Susanto Novintan Elystia Oppie Anngela Putri Indah Pratiwi Ratih Salimil Ummah Resti Yuliana Rahmawati Rizka Ahyar Hidayati Siti Awwalul Amanatur Rohmah Siti Nurriyatul K Siti Nurriyatul Kholifah Tri Kurnia Astutik Windu Handaru Yunita Diyah Safitri