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Journal : Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan

EFEK EKSTRAK ETANOL SEMUT JEPANG (Tenebrio Sp) TERHADAP PENURUNAN KADAR ASAM URAT DARAH TIKUS PUTIH JANTAN Ratih Pratiwi Sari; Novia Ariani; Dwi Rizki Febrianti
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 2 No 2 (2017): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (139.786 KB) | DOI: 10.36387/jiis.v2i2.115

Abstract

Setiap manusia memiliki asam urat, karena asam urat merupakan substansi yang normal berada di dalam tubuh. Apabila kadarnya melebihi nilai batas normal dinamakan hiperurisemia. Hiperurisemia yang dibiarkan terus-menerus tanpa pengobatan akan berkembang menjadi gout. Prevalensi angka kejadian penyakit asam urat (hiperurisemia) semakin meningkat dari tahun ke tahun, baik di negara maju maupun negara berkembang. Penelitian ini bertujuan untuk mengetahui adanya efek penurunan kadar asam urat pada tikus putih jantan dengan pemberian ekstrak etanol Semut Jepang (Tenebrio Sp).Penelitian ini merupakan penelitian eksperimental dengan rancangan pre test and post test with control group design. Penelitian ini menggunakan hewan uji sebanyak 12 ekor tikus putih jantan yang secara acak dibagi menjadi 3 kelompok terdiri dari kelompok I (kontrol negatif)  diberi aquadest, kelompok II (kelompok perlakuan) diberi ekstrak etanol Semut Jepang 2,3 mg/kgBB dan kelompok III (kontrol positif) diberi Allopurinol 27,15 mg/kgBB secara per oral. Hewan uji diinduksi dengan kalium oksonat 300mg/kgBB selama 6 hari secara intraperitoneal selama 6 hari sebelum perlakuan. Kadar asam urat hewan uji diukur dengan menggunakan alat tes strip asam urat.Hasil dari penelitian ini menunjukkan bahwa ekstrak etanol Semut Jepang (Tenebrio Sp)  dengan dosis 2,3 mg/kgBB tidak memiliki efek penurunan kadar asam urat pada tikus putih jantan.
DAYA HAMBAT EKSTRAK ETANOL KULIT BUAH PISANG KEPOK MENTAH (Musa paradisiaca forma typica) TERHADAP PERTUMBUHAN Escherichia coli SECARA IN VITRO¬ Novia Ariani; Norjannah Norjannah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 2 No 2 (2017): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (154.312 KB) | DOI: 10.36387/jiis.v2i2.116

Abstract

Tanaman pisang merupakan tanaman yang paling banyak dihasilkan dan dimanfaatkan oleh masyarakat Indonesia. Tanaman pisang memiliki berbagai macam jenis salah satunya pisang kepok. Kulit buah pisang kepok sudah banyak digunakan untuk pemanfaatan olahan pangan, namun untuk pemanfaatan sebagai obat masih terbatas padahal dalam kulit pisang mengandung metabolit sekunder flavonoid, alkaloid, saponin dan tanin yang memiliki aktivitas antibakteri. Tujuan penelitian ini adalah untuk mengetahui daya hambat ekstrak etanol kulit buah pisang kepok mentah (Musa paradisiaca forma typical) terhadap pertumbuhan Escherichia coli secara in vitro­.Jenis penelitian ini adalah non eksperimental dengan metode sumuran yang dilakukan di laboratorium Mikrobiologi Akademi Farmasi ISFI Banjarmasin. Pengambilan sampel menggunakan teknik purposive sampling dengan kriteria tertentu. Penentuan daya hambat dengan melihat zona bening disekitar sumuran.Hasil penelitian menunjukkan bahwa ekstrak kulit buah pisang kepok mentah memiliki daya hambat terhadap pertumbuhan Eschericia coli secara in vitro.
UJI DAYA HAMBAT EKSTRAK KULIT BUAH PISANG KEPOK (Musa paradisiaca forma typica) TERHADAP Shigella dysenteriae DAN Salmonella typhi Novia Ariani; Rakhmadhan Niah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 3 No 2 (2018): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (113.801 KB) | DOI: 10.36387/jiis.v3i2.184

Abstract

Masalah global yang sedang dihadapi salah satunya adalah efek samping penggunaan antibiotik baik pada negara berkembang maupun negara maju sehingga perlu dilakukan beberapa tindakan untuk mengatasi permasalahan global yang sedang terjadi. Salah satu upaya yang sedang dilakukan adalah mencari alternatif pengobatan dengan senyawa aktif yang berasal dari alam. Salah satu tanaman yang memiliki khasiat sebagai antibakteri adalah kulit pisang kepok dengan nama ilmiah Musa paradisiaca. Tujuan penelitian ini adalah untuk mengetahui ada tidaknya aktivitas zona hambat dan klasifikasi daya hambat dari ekstrak kulit pisang kepok terhadap bakteri Shigella dysenteriae dan Salmonella typhi.Jenis penelitian ini adalah penelitian eksperimental dengan metode sumuran yang dilakukan di laboratorium Mikrobiologi Akademi Farmasi ISFI Banjarmasin. Sampel yang digunakan adalah pisang kepok mentah yang berasal dari Desa Jaro yang memenuhi kriteria. Metode ekstraksi yang digunakan adalah maserasi dengan pelarut etanol 96%. Penelitian ini terbagi menjadi 2 kelompok utama yaitu kelompok ekstrak dan kontrol negatif. Zona hambat yang terbentuk diukur dengan menggunakan jangka sorong.Hasil penelitian menunjukkan bahwa ekstrak kulit buah pisang kepok dengan konsentrasi 10% memiliki daya hambat terhadap bakteri Shigella dysenteriae dan Salmonella typhi dengan klasifikasi daya hambat kuat. 
EVALUASI TINGKAT KEPATUHAN MINUM OBAT HIPERTENSI PADA PASIEN PROGRAM RUJUK BALIK DI APOTEK MITRA BANJARMASIN Novia Ariani; Noverda Ayuchecaria
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (466.148 KB) | DOI: 10.36387/jiis.v4i2.359

Abstract

Hypertension is a major factor causing cardiovascular disease and the highest cause of death in Indonesia. Mortality due to hypertension in Southeast Asia is around 1.5 million/year. In Indonesia based on 2018 Riskesdas amounted to 34.1%, with the highest prevalence in South Kalimantan 44.1%. The level of adherence to taking medication is one of the benchmarks in the success of antihypertensive drug therapy and can be used to determine the most appropriate intervention method used in increasing adherence to taking a patient's medication and knowing the effectiveness of hypertension therapy that is being undertaken by the patient. The purpose of this study was to determine the level of adherence to taking the antihypertensive medication in the patient's Program Rujuk Balik in Mitra Banjarmasin Pharmacy. This type of research is a non-experimental prospective observational with the presentation of data descriptively. The study was conducted at the Mitra Banjarmasin Pharmacy in February to March 2019 with sampling using the saturated sample method of 163 populations. Data collection is done by completing the Medication Adherence Report Scale (MARS) compliance questionnaire sheets. Data processing is processed in the form of an excel recapitulation. Data analysis uses simple frequency distribution tables which are grouped into high, medium and low levels of compliance. The results showed that of the 163 respondents used in this study who had a high level of adherence were 45 respondents (27.61%) and the moderate level of adherence was 118 respondents (72.39%). The conclusions in this study indicate that the level of adherence to taking antihypertensive drugs in patient's Program Rujuk Balik in Mitra Banjarmasin Pharmacy is moderate
TINGKAT PENGETAHUAN PASIEN TENTANG EFEK SAMPING OBAT CAPTOPRIL DAN AMLODIPIN DI PUSKESMAS SUNGAI JINGAH Novia Ariani; Dwi Rizki Febrianti; Rakhmadhan Niah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (194.254 KB) | DOI: 10.36387/jiis.v5i2.464

Abstract

Hypertension is an increase in systolic and diastolic blood pressure of more than 140 mmHg and90 mmHg. Captopril and Amlodipin are the most commonly used antihypertensive drugs, especially in Sungai Jingah Health Center. Long-term use is most likely to cause side effects. The level of knowledge of patients about side effects is very influential in knowing the early signs of the emergence of side effects and can prevent complications caused by side effects. The purpose of this study was to determine the level of patient knowledge about the side effects of captopril and amlodipine drugs at Sungai Jingah Health Center. This research is a non-experimental observational study. The population used was all hypertensive patients who received captopril and amlodipine drugs at the Sungai Jingah Health Center in April-May 2019. Samples were taken with consecutive sampling techniques that met the inclusion criteria of 55 patients. The research instrument used a questionnaire sheet that had been tested for validity and reliability consisting of 4 statements about the side effects of captopril and 5 items about the side effects of amlodipine. The data obtained is recapitulated and calculated using the percentage formula for each statement then presented descriptively. The results of the research on the level of knowledge about the side effects of captopril and amlodipine showed that out of 55 respondents 80.00% had a low level of knowledge, 3.64% had sufficient knowledge and 16.36% had good knowledge. The conclusion of this study is that the level of knowledge of patient knowledge about the side effects of captopril and amlodipine is in the low category (80.00%).
TINGKAT KEPATUHAN ODHA MINUM OBAT ARV DI POLI VCT MUTU MANIKAM RSUD DR H MOCH ANSARI SALEH BANJARMASIN Erna Prihandiwati; Novia Ariani; Yudi Hardi Susilo
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 1 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.364 KB) | DOI: 10.36387/jiis.v6i1.654

Abstract

Acquired Immunodeficiency Syndrome (AIDS ) is a collection of symptoms of a disease caused by the Human Immunodeficiency Virus (HIV) which damages the body's immunity. People With HIV AIDS (PLWHA) should undergo therapy Antiretroviral (ARV) drugs for life. Provionce was ranked 23 out of 34 provinsi in Indonesia with HIV / AIDS cases are as much as 2,274 cases. This study aims to determine the level of adherence of PLWHA taking ARV drugs in Mutu Manikam VCT Ward Dr. H. Moch Ansari Saleh Banjarmasin as well the relationship of the level of vulnerability with the characteristics of respondents. This study uses a cross-sectional design that is prospective with consecutive sampling techniques . Samples that met the inclusion and exclusion criteria were 109 PLWHA. Data is collected with the distribution of MARS questionnaires. Statistical analysis used was cross tabulation analysis with Pearson Chi Square correlation test. The results of the study showed that the level of adherence of PLWHA taking ARV drugs with a high level of adherence was 75 PLWHA (69%), the level of adherence was 34 PLWHA (31%). There was no significant correlation between adherence to taking ARV drugs with the demographic characteristics of respondents with p > 0.05 . Based on this study it was concluded that PLWHA in Mutu Manikam VCT Ward Dr. H. Moch Ansari Saleh Hospital Banjarmasin has a high level of adherence taking ARV drugs. The relationship between the level of adherence with characteristics of respondents (gender, age, education, occupation, length of treatment and comorbidities) in this study was not statistically significant.
FORMULASI DAN EVALUSI MUTU FISIK SABUN BATH BOMB EKSTRAK DAUN DADANGKAK (Hydrolea spinosa L.) Rakhmadhan Niah; Novia Ariani; Erna Prihandiwati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1608

Abstract

Dadangkak contains secondary metabolite compounds including Alkaloids, Steroids and Flavonoids. One of the compounds, namely flavonoids, has activity that can inhibit bacterial growth. The purpose of the study was to determine the effect of dadangkak leaf extract on bath bomb soap preparations and to determine the physical quality of bath boom soap dadangkak leaf extract. This research is a non-experimental research conducted at the STIKES ISFI Banjarmasin.  The study sample was dadangkak leaf extract. The research bath boom soap formulation then an evaluation of physical properties consisting of organoleptis test, soluble time, foam height, pH, specific gravity and alkali-free test. The data obtained is compared with SNI. The results of the physical properties test in formula 2 meets the requirements of physical properties with the following results pH 10; Free alkali test 0.06%; Specific gravity test 1.03g/mol; Froth height test 66 mm; Viscosity test 960 mPas. The conclusion of the study found that the formula that meets the requirements for the best physical properties of soap is formula 2 according to the s SNI 06-4085-1996.