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All Journal Pharmaciana: Jurnal Kefarmasian Pharmascience JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Pengabdian Al-Ikhlas Borneo Journal Of Pharmascientech Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal AFAMEDIS
Eka Kumalasari
Akademi Farmasi ISFI Banjarmasin
Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Physics Public Health Social Sciences

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IDENTIFIKASI KANDUNGAN BORAKS PADA MIE BASAH YANG DIJUAL DI EMPAT KELURAHAN WILAYAH BANJARMASIN TIMUR Eka Kumalasari; Wahidah Wahidah; Ratih Pratiwi Sari
Jurnal Insan Farmasi Indonesia Vol 1 No 1 (2018)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Mie basah merupakan produk pangan berbasis tepung terigu yang sangat rentan terhadap kerusakan. Oleh karena itu, perlu penambahan bahan pengawet agar mie dapat bertahan lama. Penggunaan boraks sebagai pengawet dan pengenyal ternyata telah disalahgunakan dalam industri makanan seperti halnya dalam pada pengolahan mie basah. Boraks dalam tubuh dapat menyebabkan gangguan otak, hati, lemak dan ginjal, serta orang yang mengkonsumsi akan dalam jumlah banyak dapat menyebabkan demam, depresi, kerusakan ginjal nafsu makan berkurang, gangguan pencernaan, kebodohan, kebingungan, radang kulit, anemia, kejang, pingsan bahan kematian. Oleh karena itu perlu dilakukan penelitian untuk mengetahui keberadaan kandungan boraks dalam mie basah yang dijual  di empat kelurahan (Kuripan, Sungai Bilu, Benua Anyar dan Pengambangan)  kota Banjarmasin.            Jenis penelitian yang digunakan adalah deskriptif dengan teknik pengambilan sampel yaitu teknik sampling jenuh. Analisis kualitatif boraks dalam mie basah dilakukan dengan menggunakan metode uji nyala api dan kertas tumerik. Analisis kualitatif sampel dilakukan di laboratorium Kimia Farmasi AKFAR ISFI Banjarmasin.            Berdasarkan hasil penelitian yang telah dilakukan, 10 sampel mie basah  yang terdapat diempat kelurahan (Kuripan, Sungai Bilu, Benua Anyar dan Pengambangan)  kota Banjarmasin tidak terdapat kandungan boraks dalam mie basah.
PENETAPAN KADAR FLAVONOID TOTAL EKSTRAK ETANOL 70% DAUN BAWANG DAYAK (Eleutherine palmifolia L.) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Eka Kumalasari; M. Ahlun Nazir; Aditya Maulana Perdana Putra
Jurnal Insan Farmasi Indonesia Vol 1 No 2 (2018)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

 Bawang Dayak (Eleutherine palmifolia (L.) Merr) merupakan tanaman asli Indonesia yang digunakan sebagai obat tradisional. Secara empiris umbinya mempunyai khasiat sebagai diuretik, astringen, pencahar, analgetik, mengobati luka, sakit kuning, batuk, mencret berdarah, sakit perut, disentri, radang poros usus, kanker kolon, kanker payudara, perangsang muntah, dan obat bisul dan pada bagian daunmya berkhasiat sebagai obat bagi wanita yang nifas. Pemanfaatan bawang dayak ini kebanyakan hanya pada umbinya sedangkan bagian daunnya masih belum dimanfaatkan. Salah satu kandungan daun bawang dayak yaitu flavonoid. Oleh karena itu perlu dilakukan pengujian  kadar flavonoid total dalam ekstrak etanol daun bawang dayak.Daun bawang dayak diperoleh dari desa Petuk ketimpun, Palangkaraya, Kalimantan Tengah. Berdasarkan hasil analisis dengan menggunakan metode spektrofotometri UV-Vis pada panjang gelombang 420 nm ekstrak etanol daun bawang dayak mengandung senyawa flavonoid dengan kadar sebesar 34,08 %± 0,0007.
ANALISIS ZAT PEMUTIH BERBAHAYA PADA KRIM MALAM DI KLINIK KECANTIKAN KOTA BANJARMASIN Siska Musiam; Ratu Mouly Noor; Indah Fitri Ramadhani; Amaliyah Wahyuni; Riza Alfian; Eka Kumalasari; Saftia Aryzki
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Face whitening cream is a facial lightening product that contains a mixture of chemicals and/or other ingredients with properties that can blot the black spots on the skin. Active ingredients that are often misused or added to excess in face whitening creams are mercury and hydroquinone. Whitening creams that contain mercury and hydroquinone are usually used in night creams related to the regeneration of skin cells that occur at night. The BPOM regulation states that the use of mercury is prohibited in cosmetics and the use of hydroquinone is still allowed for medical prescription purposes with a maximum limit of 4%. In this study testing of mercury and hydroquinone for night creams used in the beauty clinic of the city of Banjarmasin. Testing the presence of mercury using color reactions, and testing hydroquinone levels using spectrophotometry. The results showed that from 13 samples of night cream there were 3 positive samples containing mercury and hydroquinone simultaneously, 2 samples containing only mercury, 6 samples containing only hydroquinone, and 2 samples which did not contain mercury or hydroquinone. Of the 9 samples containing hydroquinone there were 5 samples that exceeded the maximum permissible level with the highest level was 11.41% (w/w).
PERBANDINGAN PELARUT ETANOL-AIR DALAM PROSES EKSTRAKSI DAUN BAWANG DAYAK (Eleutherine palmifolia Linn) TERHADAP AKTIVITAS ANTIOKSIDAN DENGAN METODE DPPH Eka Kumalasari; Siska Musiam
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

The immune system can be damaged by the presence of free radicals. The formation of free radicals must be prevented by antioxidants. Humanes basically do not have antioxidant reserves in their her body, so that when there is exposure to excessive the radicals then the needs body antioxidant intake from the outside. At present it is encouraged the development of antioxidants derived from plants, which are relatively easier to obtain and safe for humans consumption. Potential to antioxidant plants one of them is dayak onion leaves. Dayak onion leaves are a typical plant Borneo Central used by the Dayak tribe as medicine. To get a high active ingredient in dayak onion leaves, it is necessary to optimize the type of maceration solvent. The types of solvents used are water and ethanol. Testing of antioxidant using activities DPPH (2,2-Diphenyl-1-picrylhydrazyl) as a free radical compound. The maximum wavelength of DPPH in this study is at 519 nm. The highest IC50 value was found on dayak onion leaf extract with water solvent which was 58.62 ppm, with ethanol-water solvent of 33.71 ppm, and the smallest with ethanol solvent of 26.98 ppm. Key: antioxydan, Eleutherine palmifolia of leave, DPPH
PEMANFAATAN LIMBAH DAUN BAWANG DAYAK (Eleutherine palmifolia L. Merr) SEBAGAI KRIM ANTI AGING DENGAN EMULGATOR ANIONIK DAN NONIONIK Eka Kumalasari; Erna Prihandiwati
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.386

Abstract

Dayak onions (Eleutherine palmifolia L. Merr) are typical plants of Borneo. Pharmacologically the part tubers are proven to have a therapeutic effect. Dayak onions grow in the tropics, one of which is in the Petuk Katimpun area of ​​Palangkaraya, Central Borneo, where there land are vast Dayak onion large farms. After harvesting Dayak onions will produce agricultural waste in the form of leaves that are not utilized and left to rot. Dayak onions leek waste extract contains flavonoid compounds and has antioxidant potential. Dayak onions antioxidants can be used to inhibit the aging of the skin and as an alternative to synthetic antioxidants which are harmful to health. Waste extract has a very strong antioxidant activity with an IC50 value of 45.33 ppm. On this basis, was made four cream formulas are made with different bases. Based on the physical test results all over formulas meet the good cream requirements. Formula III is a the formula with the damping antioxidant reduction the very biggest that is 63.84% ± 0.0891.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN BAWANG DAYAK (Eleutherine palmifolia Merr.) TERHADAP Escherichia coli Eka Kumalasari; Dhea Agustina; Novia Ariani
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.497

Abstract

Dayak onions plants are mostly found in Middle of Borneo area which Dayak ethnic used for medicinal plant. General the part is only the tubers while the leaves are often removed and rarely used. Dayak leeks contain alkaloids, flavonoids, saponins, and tannins. Based on the content of dayak scallions, it is suspected that the metabolite compound has activity in inhibiting the growth of Escherichia coli. The aim of the study was determine of inhibitory for antibacterial activity of extract dayak (Eleutherine palmifolia Merr.) against Escherichia coli. The extraction of dayak leeks was done by maseration method using ethanol 70%. Antibacterial activity test dayak leeks extract using disc diffusion method with any other concentrate. Positive control is Ceftriaxone and negative control is ethanol 96%. Tool that was used for measurement of inhibitory zone is calipers. The result of this test indicate extract dayak leeks have antibacterial activity against Escherichia coli on concentrate 100%, 80%, 60%, 40%, and 20% with average diameter of inhibitory zone are 21.88mm (to strong); 19.88mm (strong); 17.68mm (strong): 9.81mm (medium); 3.32mm (weak). The result of SPSS analysis indicate that each extract concentrate have a different significant result (P<0,000).
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN BAWANG DAYAK (Eleutherine palmifolia (L.) Merr) TERHADAP PERTUMBUHAN Propionibacterium acne Eka Kumalasari; Aina Aina; Noverda Ayuchecaria; Noor Aisyah
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.584

Abstract

Acne that appears can cause facial changes, in the form of swelling, redness, purulence and causing pain so that it will create an impression that is less attractive in appearance and affects one's beauty. One of the causes of acne is Propionibacterium acne. Dayak onion leaves are one of the plant that contain antibacterial compounds. The purpose of this study was to determine the antibacterial activity of ethanol extract of onion leaves on the growth of Propionibacterium acne.The antibacterial activity of this plant needs to be reviewed through with extract group with various concentrations, positive control group (clindamycin 0.1%) and negative control group (Aquadest). The results showed that the ethanol extract of dayak onion leaves had antibacterial activity against the growth of Propionibacterium acne. The diameter of the inhibition zone formed at concentrations of 20%, 40%, 60%, 80% and 100% respectively 7.25 mm (medium), 10.43 mm (strong), 15.23 mm (strong), 18, 55 mm (strong) and 22.20 mm (very strong).
The determination of metal content, microbial contamination and dissolution assessment of the ethanol extract of pasak bumi root Laela Hayu Nurani; Eka Kumalasari; Zainab Zainab; Achmad Mursyidi; Sitarina Widyarini; Abdul Rohman
Pharmaciana Vol 7, No 2 (2017): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.452 KB) | DOI: 10.12928/pharmaciana.v7i2.6751

Abstract

 The Eurycoma longifoliais bitter therefore, to address this problem, it is prepared in a capsule form. The capsule dosage form  must has  the parameters of good quality, thus expected to increase the potential use of biodiversity and the interest of the community in consuming the medicine from the natural materials. The purpose of this research is to get the capsule product of ethanol extract of the Eurycoma longifolia root of quality through the test of total plate value and yeast yeast contamination, the determination of the metal content of Pb, Hg, Cd and the level of flavonoids released in the capsule dissolution test of ethanol extract Eurycoma longifolia root. The result of this research shows that the dissolution efficiency (DE120) capability of ethanol extract of Eurycoma longifolia root is 81,04±2,38%. Test of heavy metal content in capsule of  of ethanol extract of Eurycoma longifolia root found level of Pb equal to 4,132 ppm and not detected content of Cd and Hg in capsule. This indicates that the capsule meets the requirements set by BPOM RI. Tests for total plate numbers (ALT) and yeast capsule ethanol extract of the E. longifolia root were each obtained data of 70 x 102 colonies / g and 4 x 102 colonies / g. It also shows that the capsules meet the requirements by BPOM RI.
Analisis Kualitatif Kandungan Ibuprofen Dalam Jamu Pegal Linu Yang Beredar di Pasar Baru Permai Banjarmasin Eka Kumalasari; Linda Fitria Wahyuni; Riza Alfian
Jurnal Pharmascience Vol 5, No 1 (2018): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v5i1.5783

Abstract

ABSTRAK Ibuprofen merupakan obat yang berkhasiat untuk menghilangkan nyeri, menurunkan demam, peradangan seperti rematik dan encok. Efek samping yang paling bahaya jika digunakan dalam jangka panjang atau dalam dosis tinggi dapat menyebabkan kerusakan permukaan saluran gastrointestinal dan pendarahan. Tujuan dilakukan penelitian ini untuk mengetahui ada atau tidaknya kandungan Ibuprofen pada jamu pegal linu yang beredar di pasar Baru Permai Banjarmasin. Jenis penelitian ini adalah penelitian bersifat deskriptif. Metode penelitian yang digunakan yaitu metode analisis kualitatif dengan kromatografi lapis tipis. Penelitian dilaksanakan di Laboratorium Kimia Akademi Farmasi ISFI Banjarmasin dari tanggal 15 – 19 Juni 2017. Teknik sampling yang digunakan yaitu sampling jenuh. Sampel di ambil dari toko obat di Pasar Baru Permai Banjarmasin, didapatkan 15 sampel jamu pegal linu dengan merek berbeda. Analisis KLT menggunakan eluen dari campuran etil asetat, metanol, dan ammonia dengan perbandingan 85:10:5 dan plat KLT silica gel GF254 dengan Rf Ibuprofen yaitu 0,87. Dari hasil penelitian didapatkan 14 dari 15 sampel atau 93,3% dari total sampel mengandung Ibuprofen. Kata Kunci : Ibuprofen, Jamu Pegal Linu, KLT ABSTRACT Ibuprofen is a medicine to relieve pain, fever, inflammation such as rheumatism and gout. The most dangerous side effects when used in the long term or in high doses can cause damage to the gastrointestinal tract and bleeding. The purpose of this research is to know the presence or absence of Ibuprofen content in jamu pegal linu which is circulating in market Baru Permai Banjarmasin. The type of research is descriptive. The method used is qualitative analysis with thin layer chromatography. The research was conducted at ISFI Banjarmasin Pharmacy Laboratory from 15-19 June 2017. The sampling technique used was saturated sampling. Samples are taken from pharmacies in the in pasar Baru Permai Banjarmasin. The researcher obtained 15 herbal samples with various brands. TLC analysis used eluent from mixture of ethyl acetate, methanol, and ammonia with ratio 85: 10: 5 and KLT silica gel plate GF254 with Rf Ibuprofen was 0.87. From the results obtained 14 of 15 samples or 93.3% of the total sample positively contained Ibuprofen Keywords: Ibuprofen, Pegal Linu Herbal Medicine, TLC
PENETAPAN KADAR SIKLAMAT DALAM SIRUP MERAH YANG DIJUAL DI BANJARMASIN UTARA Siska Musiam; Marina Hamidah; Eka Kumalasari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 1 No 1 (2016): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1417.031 KB) | DOI: 10.36387/jiis.v1i1.25

Abstract

Bahan tambahan pangan adalah bahan yang ditambahkan ke dalam makanan untuk mempengaruhi sifat ataupun bentuk makanan. Salah satu bahan tambahan pangan adalah pemanis. Pemanis sintetis yang umumnya digunakan industri makanan maupun minuman adalah siklamat. Penggunaan siklamat yang berlebihan akan menyebabkan tumor dan kanker. Codex Alimentarius Commission (CAC) menetapkan bahwa kadar maksimal siklamat yang dapat dikonsumsi oleh tubuh adalah 500 – 3000 mg/kg berat badan. Oleh karena itu, dalam penelitian ini bertujuan untuk menguji kadar siklamat dalam sirup merah yang dijual di Banjarmasin Utara. Identifikasi siklamat menggunakan metode pengendapan dengan pereaksi HCl 10%, BaCl2 10% dan NaNO2 10%, dan pengujian kadar siklamat dilakukan dengan metode gravimetri. Hasil penelitian menunjukkan 6 sampel dari 15 sampel sirup merah yang dijual di Banjarmasin Utara mengandung pemanis siklamat. Kadar siklamat yang didapatkan pada sampel positif diuji dengan metode gravimetri dan didapatkan hasil berturut-turut adalah 46,21 mg/kg; 71,26 mg/kg; 97,86 mg/kg; 74,82 mg/kg; 84,46 mg/kg; dan 105,24 mg/kg berat badan. Hasil tersebut tidak melebihi ambang batas jika dibandingkan dengan kadar maksimal yang ditetapkan oleh CAC, yaitu 500 – 3000 mg/kg berat badan.Kata kunci:  bahan tambahan pangan, pemanis, siklamat, sirup merah, metode gravimetri
Co-Authors Abdul Rohman Achmad Mursyidi Aina Aina Ainun Mardiah Anna Khumaira Sari Ayuchecaria, Noverda Dhea Agustina Dwi Rizky Febrianty Erna Prihandiwati Erna Prihandiwati Febrianti, Dwi Rizki Fitria Ulfah Imam Agus Faisal Indah Fitri Ramadhani Laela Hayu Nurani Linda Fitria Wahyuni M. Ahlun Nazir M. Arsyad Marina Hamidah Maulida Yulia Rahmi Mochammad Maulidie Alfiannor Saputera Noor Aisyah Novia Ariani Putra, Aditya Maulana Perdana Rakhmadhan Niah Ratih Pratiwi Sari Ratu Mouly Noor Reza Nur Rahman Rhodiana Rhodiana Riza Alfian Saftia Aryzki Siska Musiam Sitarina Widyarini Susanto, Yugo Via Oktaviani Wahidah Wahidah Wahyuni, Amaliyah Zainab Zainab