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All Journal e-Journal Pustaka Kesehatan STOMATOGNATIC- Jurnal Kedokteran Gigi Jurnal Kedokteran Gigi Universitas Padjadjaran Health Notions Journal of Dentomaxillofacial Science Indonesian Journal for Health Sciences (IJHS) Denta: Jurnal Kedokteran Gigi Odonto dental journal
Pudji Astuti
Bagian Biomedik Fakultas Kedokteran Gigi Universitas Jember Jember, Indonesia
Dentistry Health Professions Library & Information Science Medicine & Pharmacology Nursing Public Health

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Journal : Journal of Dentomaxillofacial Science

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Viabilitas neutrofil yangdiinkubasi dalamekstrakrimpangtemulawak(Curcuma xanthorrhiza ) dan dipapar dengan Streptococcus mutans (Viability of neutrophil incubated in temulawak rhizome extract (Curcuma xanthorrhiza) and exposed by Streptococcus mutans) Ika Wahyu Purnamasari; Pudji Astuti; Tantin Ermawati
Journal of Dentomaxillofacial Science Vol. 13 No. 3 (2014): Formerly Jurnal Dentofasial ISSN 1412-8926
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v13i3.403

Abstract

Streptococcus mutans are bacteria that have important role in caries development. When caries lesion is developing, itmay invade to deeper tissues such as dental pulp and initiate cellular defenses such as neutrophil. Neutrophil is type ofleukocytes which are important in phagocytosis process. If neutrophil fails in phagocytosis, neutrophil will be lysis andcause viability of neutrophil unprotected. Temulawak rhizome extract is predicted to increase viability of neutrophilbecause it contains curcuminoids, volatile oil, saponin, flavonoid, and tannin. This research aimed of this research wasto determine the viability of neutrophil exposed by S.mutans and incubated in temulawak rhizomes extract 2.5%, 5%,7.5%,10%, and 20%. Twenty four samples were divided into 6 groups, consisting of negative control, temulawak rhizomeextract 2.5%, 5%, 7.5%, 10%, and 20%. The viability of neutrophil was observed under an inverted microscope usingtrypan blue staining. This study concluded that temulawak rhizome extract 2.5%, 5%, 7.5%, and 10% could increaseviability of neutrophil exposed by S.mutans. Temulawak rhizome extract 5% has the effective concentration to increase viability of neutrophil.
Co-Authors Abdul Rochim Abdul Rochim Agustin Wulan Suci Dharmayanti Akhmad Yusuf Sulaiman Amandia Dewi Permana Shita Amandia Dewi Permana Shita Atik Kurniawati Berlian Prihatiningrum Danang Dewantara Ananda Putra Dwi Warna Aju Fatmawati Erna Sulistyani Hardhika Oktarianda Fachri Hestieyonini Hadnyanawati I Dewa Ayu Ratna Dewanti Iin Eliana Triwahyuni Ika Wahyu Purnamasari Indah Widyanti Julia Eka Putri Ayuningtyas Lutfi Meiga Sari Melok Aris Wahyukundari Narita Ajeng Loviana Rendra Chriestedy Prasetya Resti Ayu Indriana Rindang Swandari Ristya Widi Endah Yani Rosanita Firdausi Oktaviani Rr. Nektara Titan Dianastri Sari Setyaningsih Savira Aulia Rachim Sri Lestari Tantin Ermawati Winny Adriatmoko Zahara Meilawaty Zahara Meylawaty Zahreni Hamzah