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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Journal of Agromedicine and Medical Sciences Journal of Islamic Medicine ISM (Intisari Sains Medis) : Jurnal Kedokteran
Dion Krismashogi Dharmawan
Program Studi Pendidikan Dokter, Fakultas Kedokteran, Universitas Jember, Jember.
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health

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PENGARUH SHIELDING ALUMINIUM FOIL TERHADAP PERUBAHAN KETEBALAN LAPISAN EPITEL KORNEA AKIBAT PAPARAN RADIASI GELOMBANG ELEKTROMAGNETIK PADA TIKUS WISTAR JANTAN Dion Krismashogi Dharmawan; Viskasari P Kalanjati; Abdurachman Abdurachman
JURNAL KEDOKTERAN DAN KESEHATAN Vol 7, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/JKK.V7I2.11100

Abstract

Ponsel telah diketahui memancarkan radiasi gelombang elektromagnetik (RGEM) yang digunakan sebagai media dalam telekomunikasi. Dampak buruk akibat paparan RGEM dapat terjadi pada lapisan epitel kornea mata yang secara anatomis terletak pada bagian anterior. Kami melakukan penelitian potensi aluminium foil (AF) sebagai perisai terhadap RGEM yang diukur dengan membandingkan ketebalan lapisan epitel kornea mata tikus kelompok kontrol dan perlakuan. Masing-masing tikus dimasukkan ke masing-masing kandang paparan secara terpisah. Sumber paparan RGEM berupa ponsel GSM 2100 (Taiwan) dengan SAR 0,84 – 1,86 W/kg yang tersambung wifi yang diletakkan di bagian bawah setiap kandang paparan tikus dengan paparan 4 jam /hari. Sejumlah 32 tikus dengan usia 2-3 bulan diacak dan dibagi menjadi 4 kelompok. Kelompok kontrol tanpa paparan RGEM terbagi menjadi K1 (tanpa pemberian AF) dan K2 (dengan pemberian AF). Sedangkan kelompok perlakuan yang diberi paparan RGEM terbagi menjadi P1 (tanpa pemberian AF) dan P2 (dengan pemberian AF). Hasil yang didapatkan bahwa kelompok P1 memiliki ketebalan lapisan epitel kornea paling tipis dibandingkan kelompok lainnya, namun secara statistik tidak signifikan (uji Kruskal Wallis; p value 0,147). Dari penelitian ini dapat disimpulkan bahwa, AF kemungkinan dapat menurunkan stres oksidatif yang memicu apoptosis pada lapisan epitel kornea mata dengan proses shielding sumber paparan RGEM.
Risk Factor Analysis of Recurrent Diarrhea on Toddlers in Sumberjambe Health Center Jember Regency Anita Margaret Wibisono; Ancah Caesarina Novi Marchianti; Dion Krismashogi Dharmawan
Journal of Agromedicine and Medical Sciences Vol 6 No 1 (2020)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v6i1.9657

Abstract

Recurrent diarrhea is diarrhea that occurs repeatedly within one to three months. Toddler is the highest group suffering of diarrhea. Diarrhea is the second leading cause of death on toddler. This research aims to analyze the effect of risk factors of recurrent diarrhea on toddler in Sumberjambe Health Center Jember Regency. This type of research is observational analytic with case control design. The sample is 50 cases and 50 controls. The sampling technique used consecutive sampling method. The research was conducted in December 2018 to January 2019 using a questionnaire. Data analysis using Chi Square test and Logistic Regression test. Chi Square analysis results are child’s age (p= 0.003), gender (p= 1,000), exclusive breastfeeding (p= 0.044), measles immunization (p= 0.387), nutritional status (p= 0.840), hand nail hygiene (p= 0.395), mother’s age (p= 0.435), mother’s education level (p= 0.263), mother’s knowledge (p= 0.494), hand washing habit (p= 0.684), and family income (p= 0.773). Logistic Regression analysis results are child’s age (p= 0.002) and exclusive breastfeeding (p= 0.499). The conclusions of this study are child’s age and exclusive breastfeeding have influence of recurrent diarrhea on toddler and child's age is the most influential risk factor of recurrent diarrhea on toddler. The suggestion of this research is that it needs to research other risk factors and mothers are required to give exclusive breastfeeding. Keywords: risk factors, recurrent diarrhea, toddler
Antibiotic Sensitivity Test on Staphylococcus Aureus Detected in Sputum of Patients with Pneumonia Treated in Hospitals Dini Agustina; Diana Chusna Mufida; Hanifa Rizki A.S.; Dion Krismashogi Dharmawan
Journal of Agromedicine and Medical Sciences Vol 5 No 1 (2019)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v5i1.9267

Abstract

Pneumonia is a respiratory tract infection that attacks the pulmonary parenchyma. This disease can be caused by bacteria, one of which is Staphylococcus aureus. Antibiotics have an important role to play in reducing the morbidity and mortality incidence of pneumonia, but currently, the incidence of resistance antibiotics is increased. The purpose of this study was to determine the sensitivity of antibiotics Staphylococcus aureus in pneumatic sputum patients. The design of this study was observational descriptive, using sputum samples from pneumonia patients in Subandi and Paru Jember hospitals in November to December 2018. The identification of bacteria in sputum was continued by testing the sensitivity of bacteria to antibiotics. The antibiotics used in this study were chloramphenicol, gentamicin, amikacin, levofloxacin, ampicillin-sulbactam, cotrimoxazole, and ciprofloxacin — data obtained in the frequency distribution table. Of the ten sputum that was successfully cultured, four Gram-negative bacilli bacteria and six Gram-positive coccus bacteria were obtained. The results approved the six Gram-positive coccus bacteria, detected as Staphylococcus aureus. The antibiotic resistance of Staphylococcus aureus to ampicillin-sulbactam was high. Keywords: antibiotic sensitivity, bacteria, pneumonia
The Effectiveness of Vitamin C Addition to Blood Glucose Levels of Hyperglycemic Mice with Glimepiride Treatment Indi Kamilia Fitri; Cholis Abrori; Dion Krismashogi Dharmawan
Journal of Agromedicine and Medical Sciences Vol 6 No 3 (2020)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v6i3.9994

Abstract

In people with diabetes mellitus (DM) there is a decrease in basal vitamin C levels which is thought to be a result of oxidative stress in the condition of hyperglycemia that it needs to increase vitamin C as an antioxidant. Hyperglycemia in DM needs to be lowered by pharmacological therapy, named glimepirid so the purpose of this study is to determine the effectiveness of vitamin C addition to the reduction of KGD hyperglycemic mice with glimepirid treatment. This study is true experimental with a sample of 25 mice 20-30 grams and divided into five groups, first the control group (K0); STZ induction group (K1); STZ induction group with glimepirid treatment (K2); STZ induction group with the treatment of vitamin C (K3); STZ induction group by treatment of a combination of glimepirid and vitamin C (K4). STZ is injected intraperitonially 150 mg / kgBB. All groups were measured for KGD 1 after induction of STZ and KGD 2 after treatment for fourteen days. The results of the STZ induction group with the treatment of a combination of glimepirid and vitamin C (K4) experienced a smaller and not significant decrease in BSL in the STZ induction group with a single glimepirid (K2) treatment. These results are thought to have an influence from interactions between drugs that cause one drug to not work optimally. The conclusion of this study is that administration of glimepirid, vitamin C, or both can reduce blood glucose levels in hyperglycemic mice with the greatest decrease occurring in the glimepirid group.
CHubungan Tingkat Beban Pekerjaan terhadap Kejadian Kifosis pada Buruh Panggul di Pasar Tradisional Tanjung Jember Periode Bulan Januari 2020 Totalenesya Reforrent Sutikno; Dion Krismashogi Dharmawan; Erfan Efendi
Journal of Islamic Medicine Vol 6, No 1 (2022): JOURNAL OF ISLAMIC MEDICINE EDISI MARET 2022
Publisher : Faculty of Medicine and Health Science, Universitas Islam Negeri Maulana Malik Ibrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jim.v6i1.11261

Abstract

Background: Kyphosis is  vertebrae disorder characterized with increased of vertebrae curve in sagital line of 40o Cobb angle. Kyphosis is caused by degenerative proces,, neuromuscular disease, tumor, trauma, congenital abnormalities and unergonomic posture at the moment of carriying weights. One of kyphosis risk factor is excessive weights on the back in long duration. The complication of kyphosis such as vertebrae compression fracture could cause pain and deformities. Objective: Purpose of this research is to describe the correlation between workload level in carrier workers towards kyphosis at Tanjung Market, Jember. Methods: This research was observational analitic, cross sectional method, and total sampling. The respondents were 32 male carrier workers and 32 controls.. Data was obtained by interview and Cobb angle measurement on 1st and 12th thoracal vertebrae using inclinometer. Statistical test was done by Spearman correlation test. Results: The data analysis showed that p value for working time, work tenure, and transport weights toward kyphosis prevalence sequentially were 0,778; 0,326; and 0,739. Male carrier workers in Tanjung Traditional Market used to carry 50-100 Kg of weights once they start to transport. The working time of the carrier workers each day were seven hours and 15 years for work tenure in average. There were two carrier workers (6,2%) suffering of kyphosis (50 years old) with working time 8 hours per day, 10 years for work tenure, and 50 Kg for transport weights.. Conclusion: This research had proven that there is no any correlation between working time, work tenure, and carried load level towards kyphosis in carrier workers of Tanjung Market Jember.
Gambaran faktor risiko dan tingkat risiko stroke iskemik berdasarkan stroke risk scorecard di RSUD Klungkung Ni Made Trismarani Sultradewi Kesuma; Dion Krismashogi Dharmawan; Heni Fatmawati
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (307.353 KB) | DOI: 10.15562/ism.v10i3.397

Abstract

Latar Belakang: Indonesia memiliki angka beban stroke terbanyak kedua setelah Mongolia yaitu sebanyak 3.382,2/100.000 orang berdasarkan DALYs (disability-adjusted life-year). Berdasarkan profil kesehatan provinsi Bali, tipe stroke yang memiliki tingkat prevalensi yang tinggi adalah stroke iskemik. Strategi praktis dalam mengatasi beban akibat stroke harus difokuskan pada pencegahan dan penanganan berdasarkan faktor risiko. Tujuan penelitian ini adalah untuk mengetahui hubungan antara faktor-faktor risiko dengan tingkat risiko penderita stroke iskemik yang rawat inap di RSUD Klungkung Bali periode Oktober 2017 sampai dengan September 2018.Metode: Penelitian ini merupakan penelitian analitik observasional dengan desain cross sectional. 65 Subyek penelitian yang sesuai dengan kriteria inklusi, diambil dari data rekam medis pasien stroke iskemik yang rawat inap di RSUD Klungkung. Variabel yang diteliti dalam penelitian ini yaitu usia, jenis kelamin, tekanan darah, kadar kolesterol, riwayat merokok, indeks massa tubuh (IMT), aktivitas fisik, riwayat diabetes, riwayat fibrilasi atrium, dan riwayat stroke dalam keluarga.Hasil: Dari total 65 pasien stroke iskemik yang rawat inap di RSUD Klungkung, paling banyak berada pada kelompok usia ≥ 55 tahun – 64 tahun dengan usia rerata 61,45 ± 12,016 tahun. Pasien berdasarkan jenis kelamin didominasi oleh laki-laki dengan perbandingan kejadian stroke iskemik antara laki-laki dan perempuan sebesar 2,4:1. Hasil penilaian tingkat faktor risiko dengan Stroke Risk Scorecard (SRS), 51 orang (78,5%) memiliki risiko tinggi, 9 orang (13,8%) memiliki risiko sedang, dan 5 orang (7,7%) memiliki risiko rendah.Simpulan: Uji statistik chi-square menunjukkan adanya hubungan yang signifikan antara tingkat risiko stroke iskemik dengan indeks massa tubuh, tekanan darah, riwayat merokok, riwayat diabetes, dan kadar kolesterol (p<0,005).Introduction: Indonesia is the second highest country of stroke burden after Mongolia, which are 3,382.2 / 100,000 people based on DALYs (disability-adjusted life-year). Based on the health profile of the province of Bali, the type of stroke that has high prevalence rate is ischemic stroke. Practical strategies in overcoming the burden of stroke must be focused on prevention and treatment based on risk factors. The study aims to determine the relationship between risk factors and the level of risk of ischemic stroke patients hospitalized at RSUD Klungkung Bali.Methods: This study is observational analytic study with a cross sectional design that includes 65 patients taken from the medical records. The variables studied are age, gender, pressure blood, cholesterol levels, smoking history, body mass index (BMI), physical activity, history of diabetes, history of atrial fibrillation, and history of stroke in the family. Data analysis techniques used were univariate analysis and bivariate analysis.Result: The most characteristics based on age group is ≥ 55 years - 64 years with an average age of 61.45 ± 12.016 years. Patients are dominated by men (2,4:1). The assessment of the level of risk factors in each sample using the Stroke Risk Scorecard (SRS), 51 people (78.5%) had a high risk, 9 people (13.8%) had moderate risk, and 5 people (7.7%) has a low risk of ischemic stroke.Conclusion: The chi-square statistical analysis showed a significant relationship between the risk level of ischemic stroke with body mass index, blood pressure, smoking history, history of diabetes, and cholesterol levels (p<0,005).
Co-Authors Abdurachman Abdurachman Ancah Caesarina Novi Marchianti Anita Margaret Wibisono Cholis Abrori, Cholis Diana Chusna Mufida Dini Agustina Erfan Efendi Hanifa Rizki A.S. Heni Fatmawati Indi Kamilia Fitri Ni Made Trismarani Sultradewi Kesuma Totalenesya Reforrent Sutikno Viskasari P. Kalanjati