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All Journal Medali Jurnal : Media Dental Intelektual ODONTO Dental Journal Insisiva Dental Journal : Majalah Kedokteran Gigi Insisiva Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Odonto dental journal Jurnal Pengabdian Masyarakat Dentmas Journal of Fisheries & Marine
Arlina Nurhapsari
Fakultas Kedokteran Gigi, Universitas Islam Sulan Agung
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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EFEK COENZYME Q10 TERHADAP SEL NEUTROFIL DAN SEL MAKROFAG PADA MODEL TIKUS PULPITIS Nurhapsari, Arlina; Kusuma, Andina Rizkia P; Indraswary, Recita; Widyasari, Ferina; Rahma, Destari Amelia
Syifa'Medika Vol 12, No 1 (2021): Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v12i1.3296

Abstract

Pulpitis akut merupakan penyakit peradangan pulpa dengan prevalensi yang tinggi di Indonesia. Pada proses peradangan awal sel yang paling banyak berperan adalah sel neutrophil dan makrofag. Proses inflamasi tidak terlepas dari peran Reactive Oxygen Species (ROS). Reactive Oxygen Species dapat diturunkan kadarnya dengan pemberian antioksidan. Coenzyme Q10 merupakan salah satu antioksidan alami dengan kandungan Ubiquinone, bahan ini belum banyak diteliti penggunaannya di bidang kedokteran gigi. Penelitian ini bertujuan mengetahui pengaruh pemberian Coenzyme Q10 terhadap jumlah sel neutrofil dan sel makrofag pada gigi maksila tikus yang mengalami pulpitis. Jenis penelitian ini adalah experimental laboratorium in vivo. Model pulpitis diinduksi pada 15 tikus Sprague Dawley jantan dengan membuka pulpa gigi maksila pertama. Tikus dibagi menjadi tiga kelompok yaitu kelompok A1 (Coenzyme Q10); A2 (eugenol) dan A3 (akuades). Gigi maksila diambil setelah hari ke-3 dan dilakukan pemeriksaan histologi. Hasil uji Kruskal Wallis menunjukkan perbedaan signifikan antara ketiga kelompok tersebut. Pada uji Mann Whitney menunjukkan tidak ada perbedaan signifikan pada kel A1 dan A2. Kesimpulan dari penelitian ini adalah Coenzyme Q10 mempunyai kemampuan yang sama dengan eugenol dalam menurunkan jumlah sel inflamasi.
EFEKTIVITAS EKSTRAK KULIT BUAH MANGGIS (Garcinia manggostana Linn) DALAM MENGHAMBAT PERTUMBUHAN BAKTERI Streptococcus mutans Ferry Gustiningrum; Arlina Nurhapsari; Recita Indraswary; Uswatun N.A Darjono
Jurnal Medali Vol 1, No 1 (2013): Media Dental Intelektual
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.v1i1.91

Abstract

Caries known as disease which hard to lose. The major causative of caries is Streptococcus mutans bacteria. Streptococcus mutans can be inhibited by antibacterial agent. Substances in the pericarp of mangosteen fruit (Garcinia mangostana Linn) was reported had an antibacterial ability. These compounds such as xanthone, saponins, tannins and flavonoids. The purpose of this study was to examined the effectiveness of mangosteen pericarp extracts (Garcinia mangostana Linn) for inhibite the growth of Streptococcus mutans, which the major causative bacteria of dental caries.This study used experimental laboratory with 25 sample were divided into 5 groups concentration which are 3.125%, 6.25%, 12.5% , 25%, and 50%. Streptococcus mutans culture on blood agar and the disks have been soaked in the mangosteen pericarp extracts.The disks placed on the blood agar. Effectiveness of antibacterial mangosteen’s pericarp extract formed in the presence of inhibition zones around paper disc and measured with sliding calipers (mm). The average inhibition zone, analyzed with the Kruskal-Wallis test followed by Mann Whitney test.The result of this research was significant difference (sig<0,05) from the Kruskal-Wallis test with the probability 0,000. The Mann Whitney test result is also said significant (p<0,05).Conclusion of this study, the mangosteen pericarp extracts (Garcinia mangostana Linn) with minimal concentration 3.125% can inhibit Streptococcus mutans. Keywords: Anti bacterial effect, Mangosteen’s pericarp extract, Streptococcus mutans
PERBANDINGAN DAYA HAMBAT ANTARA DUA JENIS PROBIOTIK YANG BERBEDA TERHADAP BAKTERI Aggregatibacter actinomycetemcomitans Hesty Pradini; Sutji Asri Tjitra A; Rochman Mujayanto; Arlina Nurhapsari
Jurnal Medali Vol 1, No 1 (2013): Media Dental Intelektual
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.v1i1.81

Abstract

Probiotics is live microorganisms which is given in adequate amounts in the form of food Probiotics is live microorganisms which are given in adequate amounts in the form of food or supplements provide health benefits to the body. Probiotics Bacteria has to unleash antimicrobial substances such as organic acids, hydrogen peroxide and bacteriocins. The aim of the study is to know inhibition differences between two different types of probiotic bacteria toward Aggregatibacter actinomycetemcomitans.The study was conducted by using two different types of probiotics, the probiotics containing bacteria Lactobacillus acidophilus and Bifidobacterium and probiotic containing bacteria Lactobacillus bulgaricus and Streptococcus thermophiles, and sterile distilled water as a negative control group. The antibacterial properties of the extracts were tested using by chamber diffusion method and incubated ± 24hours, then by measuring inhibition zone (light zone) around the chamber using calipers.The average resistance zone of probiotics which contains probiotic bacteria Lactobacillus acidophilus and Bifidobacterium, probiotic bacteria Lactobacillus bulgaricus and Streptococcus thermophiles successive sequence were 3.13 mm, and 1.87 mm. There were differences with One Way Anova in the groups treated with significance of 0.000.From the results, it concluded that there were differences in the inhibition of the two types of probiotic bacteria on the growth of Aggregatibacter actinomycetemcomitans. Keywords : Probiotics, Lactobacillus acidophilus and Bifidobacterium, Lactobacillus bulgaricus and Streptococcus thermophiles, resistibility, Aggregatibacter actinomycetemcomitans
SURVEI MENGENAI PENGETAHUAN DAN SIKAP DOKTER GIGI TENTANG FLUORIDA BAGI KESEHATAN GIGI DI KOTA SEMARANG (Berdasarkan Usia, Jenis Kelamin, Dan Jenis Pekerjaan Dokter Gigi) Kris Adityawarman; Diyah Fatmasari; Arlina Nurhapsari
Jurnal Medali Vol 2, No 1 (2015): Media Dental Intelektual
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.v2i1.446

Abstract

Karies merupakan salah satu penyakit kronis yang paling umum terjadi di dunia. Penggunaan fluorida sebagai tindakan pencegahan karies sudah lama dilakukan di negara-negara maju. Dokter gigi mempunyai peranan yang sangat penting sebagai sumber informasi tentang fluorida terhadap tindakan pencegahan kesehatan gigi untuk masyarakat. Peningkatan pengetahuan dokter gigi tentang fluorida sangatberpengaruh terhadap sikap dokter gigi dalam tindakan pencegahan karies gigi dan akan meminimalkan terjadinya fluorosis pada gigi. Tujuan penelitian ini untuk mengetahui perbedaan mengenai pengetahuan dan sikap dokter gigi tentang fluorida bagi kesehatan gigi (berdasarkan usia, jenis kelamin, dan jenis pekerjaan dokter gigi).Jenis penelitian ini analitik observasional dengan pendekatan survey cross sectional. Data penelitian ini diperoleh dengan menggunakan kuesioner. Pengetahuan dalam penelitian ini adalah pengetahuan dokter gigi tentang fluorida sebagai bahan untuk pencegahan terjadinya karies, sedangkan untuk sikap yaitu respon dari dokter gigi terhadap penggunaan fluorida untuk mencegah terjadinya karies. Uji chi-squaredigunakan sebagai alat analisis dengan nilai p < 0,05.Hasil penelitian menunjukkan terdapat perbedaan pengetahuan dokter gigi tentang fluorida berdasarkan kelompok usia (p=0,01) dan jenis pekerjaan (p=0,001), namun tidak terdapat perbedaan antara dokter gigi laki-laki dan perempuan (p=0,661). Tidak terdapat perbedaan sikap dokter gigi terhadap fluorida berdasarkan kelompok usia (p=0,245) dan jenis kelamin (p=0,481), namun terdapat perbedaan berdasarkanjenis pekerjaan (p=0,039).Sikap dan pengetahuan dokter gigi terhadap fluorida berdasarkan usia dan jenis pekerjaan dokter gigi menunjukkan perbedaan signifikan, sedangkan berdasarkan jenis kelamin tidak menunjukkan perbedaan yang signifikan.
HUBUNGAN IBU PEROKOK PASIF SEBAGAI FAKTOR LINGKUNGAN TERHADAP KEJADIAN CELAH BIBIR DENGAN ATAU TANPA CELAH PALATUM NONSINDROMIK (Pada Pasien RSI Sultan Agung Semarang Bulan Juni 2012) Beti Ratnasari; Rizki Amalina; Yayun Siti Rochmah; Arlina Nurhapsari
Jurnal Medali Vol 1, No 1 (2013): Media Dental Intelektual
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.v1i1.76

Abstract

Nonsyndromic cleft lip with or wihout cleft palate (CL±CP) is a congenital defect caused by genetic and environmental factors. One of the its environmental factors is passive smoking mother. The increasing risk of CL±CP in passive smoking mothers occurs due to the fetal hypoxia caused by carbon monoxide and nicotine in cigarette smoke. The aim of this study is to determine the relationship of passive smoking mothers as environmental factor towards the incidence of nonsyndromic CL±CP in patients of Sultan Agung Islamic Hospital Semarang June 2012.This study used cross sectional method. The samples were 16 CL±CP patients at Sultan Agung Islamic Hospital Semarang June 2012 with their mothers who had fulfilled exclusion and inclusion criteria stated in the questionnaire and 16 control subjects. The motherswere qualified as passive smokers if they met all requirements. The data analysis involved Chi-square test as descriptiveand hypothesis test.The analysis results showed significant relationship (p<0,05) with prevalence ratio (RP)=2,647 and confidence interval (CI) 95%=1,083-6,469. Twelve out of sixteen CB±CP patients’ mothers were passive smokers.  In conclusion, there is a relationship between passive smoking mothers as environmental factor towards the incidence of nonsyndromic CL±CP in patients of Sultan Agung Islamic Hospital Semarang June 2012.Keywords: passive smoking mothers, cleft lip, cleft lip with cleft palate, nonsyndromic, carbon monoxide, nicotine, hypoxia
PENGARUH PERMAINAN ULAR TANGGA MODIFIKASI TERHADAP PENGETAHUAN KESEHATAN GIGI DAN MULUT PADA ANAK (Studi terhadap Siswa SD N 4 Tanggungharjo, Kecamatan Grobogan) Ani Labibah; Arlina Nurhapsari; Rochman Mujayanto
Jurnal Medali Vol 2, No 1 (2015): Media Dental Intelektual
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.v2i1.441

Abstract

Pendidikan kesehatan gigi adalah upaya untuk meningkatkan kesehatan gigi dan mulut sejak dini. Pemberian pendidikan kesehatan gigi harus menarik, penjelasan yang menarik tanpa mengurangi konten pendidikan. Pemberian pengetahuan dapat dilakukan dengan permainan ular tangga yang telah dimodifikasi. Tujuan dari penelitian ini adalah untuk menganalisis pengaruh permainan ular tangga modifikasi terhadap pengetahuan kesehatan gigi da mulut pada anak. Metode penelitian ini menggunakan analitik deskriptif dengan rancangan pre dan post test. Sampel dikumpulkan dengan menggunakan metode stratified random sampling yang terdiri 73 responden berdasarkan kriteria inklusi dari SD N VI Tanggungharjo, Grobogan. Variabel independen adalah permainan ular tangga modifikasi. Variabel terikat adalah pengetahuan tentang kesehatan gigi dan mulut pada anak. Data dikumpulkan dengan menggunakan kuesioner dan dianalisis dengan menggunakan uji Paired t - test dengan p < 0,05. Berdasarkan analisis menggunakan uji Paired t - test menunjukkan terdapat pengaruh permainan ular tangga terhadap peningkatan tingkat pengetahuan anak yang ditunjukkan dari nilai signifikansi 0, 000 (p < 0,05). Dari hasil penelitian tersebut dapat disimpulkan bahwa permainan ular tangga modifikasi mempengauhi peningkatan pengetahuan kesehatan gigi dan mulut pada anak.
THE EFFECT OF DIFFERENT LIGHT CURED UNIT INTENSITIES ON THE DEPTH OF POLYMERIZATION OF BULK FILL SCULPTABLE COMPOSITE RESIN RESTORATIONS Alphania Esty Luthfaida; Arlina Nurhapsari; Helmi Fathurrahman
Jurnal Medali Vol 3, No 1 (2021): Media Dental Intelektual September 2021
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.v3i1.16382

Abstract

Background : The latest development of dental material restoration is a bulk fill sculptable composite resin. This material can be applied to a 4 mm cavity at once irradiation. The success of polymerization can be affected by improper irradiation. Both the physical and mechanical properties of the material also can be decreased by improper irradiation. This study aimed to determine the effect of different light-cured unit intensities on the depth of polymerization of bulk fills sculptable composite resin restorations.Method : This research method was an experimental analytic type of post-test only control group design laboratory, consisting of 24 bulk fill sculptable composite resin with a diameter of 4mm x 6mm thickness divided into 6 groups:A1(3M ESPE-low intensity),A2(3M ESPE-high intensity),A3(3M ESPE-soft start intensity),B1(Ivoclar vivacity-low intensity),B2(Ivoclar vivadent-high intensity) and B3(Ivoclar vivadent-soft start intensity). Result : The results showed a significant effect of the low, high, and soft start intensity light-cured units in the bulk fill sculptable composite resin groups by Kruskal-Wallis test 0.00 (p <0.05).Conclusion : The best polymerization depth of bulk fill sculptable composite resin was 3M ESPE and it was affected by the high and low-intensity light-cured units
EFEKTIFITAS ANTIBAKTERI EKSTRAK BUAH MENGKUDU (Morinda citrifolia, Linn) DALAM MEMBUNUH BAKTERI Enterococcus faecalis Berti Silviana Intani; Arlina Nurhapsari; Rochman Mujayanto; Rama Putranto
Jurnal Medali Vol 1, No 1 (2013): Media Dental Intelektual
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.1.1.70-74

Abstract

Noni fruit (Morinda citrifolia, Linn) consists of antibacterial compound of phenolic. The phenolic derivatives of noni fruit are alizarin, antrakuinon, and acubin, these derivatives can kill bacteria by damaging cell membrane and protein denaturation. The aim of this study is to determine the effectiveness of antibacterial noni fruit extract in killing bacteria Enterococcus faecalis.The study was conducted by making various concentrate of noni fruit extract, that is 100%, 50%, 25%, 12,5%, and 6,25%, and cresophene as the positive control. Testing samples of the bacterium Enterococcus faecalis suspension by putting a disc that has been soaked in various concentrations extract and cresophene on a petri dish, and then incubated for 24 hour, followed with measurement of kiling zone (light zone) around the discs using calipers.The average killing zones formed in extracts 100%, 50%, 25%, 12.5%, 6.25% and cresophene respectively were 13.9 mm, 9.6 mm, 7.3 mm, 6.4 mm , 6mm, and 27.1 mm. The data obtained were tested with One Way Anova and gained a result that there was a difference in the treatment group with significance of 0.000.It can be concluded that noni fruit extract was effective in killing bacteria Enterococcus faecalis.The higher concentration of noni fruit extract, more effective in killing bacteria Enterococcus faecalis. Keyword: antibacterial, noni fruit extract, killing zone of Enterococcus faecalis.
EFEKTIVITAS OBAT KUMUR PROPOLIS, KLORHEKSIDIN DAN POVIDON IODINE TERHADAP INDEKS PLAK (Studi Mahasiswa Fakultas Kedokteran Gigi Universitas Islam Sultan Agung Semarang berusia 18-23 tahun) Mayya Nailullathifah; Diyah Fatmasari; Ade Ismail A.K; Arlina Nurhapsari
Jurnal Medali Vol 1, No 1 (2013): Media Dental Intelektual
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.v1i1.78

Abstract

Nowdays various chemical and herbal mouthwash has been circulating. Propolis is one of the herbal mouthwash product derived from bee Apis sp. While chlorhexidine and povidon iodin are chemical mouthwash known to control the plaque growth. Research’s objective determine the effect of propolis mouthwash to plaque index decrease, compared to mouthwash ‘chlorhexidine and povidone iodine.The study was conducted on students 18-23 years old from the Dentistry Faculty, Islamic University Sultan Agung Semarang. Samples were divided into three groups, each group consits of 11 people for mouthwash chlorhexidine, povidon iodin, and propolis. Measurement of plaque index using PHP (Patient Hygiene Performance Index) Plaque Index by Podshadley and Haley.The majority of criteria dental plaque before rinsing were moderate in the group propolis, chlorhexidine and povidon iodin. The majority of criteria dental plaque after rinsing are moderate in the propolis, chlorhexidine and povidone (p < 0,05) iodine. P-value from one way anova test on the plaque index after rinsing shows that plaque index mean was significantly different. The post hoc test showed plaque index decrease by propolis is equivalents to chlorhexidine and higher than povidon iodin. The research design was pre and post test control group.It was concluded that propolis mouthwash influence to plaque index decrease. Keywords: propolis, chlorhexidine, povidon iodin, plaque index
PENATALAKSANAAN GIGI PREMOLAR KEDUA MAKSILA DENGAN SALURAN AKAR VERTUCCI TIPE V - laporan Kasus Arlina Nurhapsari
ODONTO : Dental Journal Vol 1, No 1 (2014): July 2014
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.1.1.53-56

Abstract

Background: The aim of the case report is to demonstrate the importance of knowing the root canals configuration in the maxillary second premolars. Maxillary second premolars usually have one root canal, however in several cases there is more than one root canal with a variety of configurations. Method: multiple visit root canal treatment with a crown down technique on the maxillary second premolar with unusual root canals configuration which is confirmed using radiograph. Result: Based on radiograph, it was identified Vertucci type V root canal on the maxillary second premolars. After biomechanical preparation, obturation was conducted. When patient controlled, there were not problem and inflammation. Conclusion : This report described and discussed about the possibility of root canals variation on the maxillary second premolars. Careful examination using radiograph and deep knowledge, it is identified by the clinician in treating root canal treatment on that premolars.
Co-Authors Ade Ismail Ade Ismail A.K Alphania Esty Luthfaida Andhika Ambo Andina Rizkia Putri Kusuma Andina Rizkia Putri Kusuma Ani Labibah Aning Susilowati Anitalia Sukma Permata Sari Atiek Amalia Ahsanti Balqis Nureska Khomsiana Benni Benyamin Berti Silviana Intani Beti Ratnasari Chariza Hanum Mayvita Iskandar Denis Yusfa Diyah Fatmasari Erwid Fatchur Rahman Ferry Gustiningrum Grahita Aditya Hafid Nur Arzanudin Helmi Fathurrahman, Helmi Hesty Pradini Irma Dewi Ratnawati Islamy Rahma Hutami, Islamy Rahma Kris Adityawarman Kusuma, Andina Rizkia P M. Dian Firdausy Mayya Nailullathifah Moh. Baehaqi Muh. Dian Firdausy Muhammad Dimas P. P. Novia Indasari Rahma, Destari Amelia Rahmawati Sri Praptiningsih Rama Putranto Recita Indraswary Recita Indraswary Regilia Shinta Mayangsari Rifqi Wahyu Febrian Rizki Amalina Rochman Mujayanto Rosa Pratiwi Rosalita Amelia Rr. Sarah Ladytama Rusna Fiki Kafalia Sandy Christiono Savira Nurazky Yuniar Savira Nurazky Yuniar Seno Pradopo shella indri novianty Silvia Vera Indrawati Suparmi Sutji Asri Tjitra A Syarifah Nur Laili Siyam Uswatun N.A Darjono Widyasari, Ferina Yayun Siti Rochmah Yayun Siti Rochmah Rochmah Yunita Setyaningrum Yunita Styaningrum Zurairah Ibrahim