Nursanti Nursanti
Departemen Farmasi Universitas Indonesia

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Studi Hubungan Kerapatan Vegetasi Lamun dengan Laju Sedimentasi di Perairan Teluk Awur dan Bandengan Jepara Pada Periode Juni – Juli 2012 Nursanti, Nursanti; Riniatsih, Ita; Satriadi, Alfi
977-2407769
Publisher : Departemen Ilmu Kelautan, Fakultas PerikanJurusan Ilmu Kelautan, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1519.429 KB) | DOI: 10.14710/jmr.v2i3.3128

Abstract

Teluk Awur and Bandengan waters are located in Jepara which have different conditions and also the waters are still good for seagrass growth. Seagrass has one physical function as a sediment catcher in coastal waters. The sedimentation rate in the Teluk Awur and Bandengan waters affected by seagrass density, flow velocity, and sediment composition. The purpose of this research is to determine the relationship of seagrass vegetation density with the rate of sedimentation in the Teluk Awur and Bandengan waters, Jepara. This reaserch was conducted in June-July 2012. in the Teluk Awur waters discovered 6 genus such as Enhalus, Thalassia, Thalassodendron, Cymodocea, Halodule, and Syringodium, with an average value of density 198.03 individu/m2. While Bandengan waters was found 7 genus such as Enhalus, Thalassia, Thalassodendron, Cymodocea, Halodule, Syringodium and Halophila, with average value of density 457.1 individu/m2. The results showed that the average value of sedimentation rate in the Teluk Awur waters 438.74 g/m2/week, while the Bandengan waters 667.42 g/m2/week. The R2 value of relationship between Seagrass density with the sedimentation rate in the Teluk Awur waters 0.566. While the R2 of Bandengan waters 0.073. The Teluk Awur waters contain a little lanau sediment so it has a little sedimenation. Bandengan waters contain higher lanau sediment so it has more sedimentation.
Eksplorasi dan Karakterisasi berbagai Kristal Ibuprofen Yanuar, Arry; Nursanti, Nursanti; Anwar, Effionora
Majalah Ilmu Kefarmasian Vol. 7, No. 2
Publisher : UI Scholars Hub

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Abstract

Ibuprofen is an analgesic anti-inflammatory nonsteroidal (AINS). Generally, ibuprofen have a bad flowability because a high cohesivity. Another problem in manufacturing is the high tendency for sticking to the punches. Besides these disadvantageous properties, ibuprofen indicates bad dissolution behavior because of its hydrophobic structure. To improve the properties of ibuprofen can be used crystallization method with using variation of solvents. In this experiment observed crystallization method by cooling, evaporation, and water presence, which used methanol, ethanol, and acetone solvents. Of all the crystallization results are produced white prism-shaped crystalline. The selected method is cooling method, which is characterized using Scanning Electron Microscopy (SEM), powder X-ray diffraction, and Differential Scanning Calorimetry (DSC). These three characterizations indicate transformation of crystal form which compared with ibuprofen’s standard. The selected method also produces non cohesive powder which have the size particle is 710-1180µm, compressibility index: IBMD 14.2%, IBED 16.6%, IBAD 17.1%; angles of repose: IBMD 28.1º, IBED 29.7º, IBAD 30.1º, and have higher solubility than the common crystal’s solubility. The result indicates that crystallization method is able to improve flowrate, compressibility index, and dissolution rate properties of ibuprofen’s standard.