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All Journal Jurnal Farmasains Jurnal Manajemen Pelayanan Kesehatan Jurnal Gizi Klinik Indonesia Pharmaciana: Jurnal Kefarmasian Althea Medical Journal Jurnal Kedokteran Meditek Jurnal Farmasi Klinik Indonesia INDONESIAN JOURNAL OF PHARMACY JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Malang Neurology Journal Jurnal Farmasi Sains dan Komunitas (JFSK) Universa Medicina Berkala Ilmiah Kedokteran Duta Wacana JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Ilmiah Ilmu Kesehatan: Wawasan Kesehatan Callosum Neurology Journal : Jurnal Berkala Neurologi Bali JFIOnline JURNAL FARMASI GALENIKA YARSI Medical Journal Majalah Kedokteran Neurosains Cermin Dunia Kedokteran

Rizaldy Pinzon

Fakultas Kedokteran Universitas Kristen Duta Wacana Yogyakarta

Author-ID : 342724

Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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PENGEMBANGAN PROSES VERIFIKASI PRA-OPERASI UNTUK MENINGKATKAN KESELAMATAN PASIEN DI RUMAH SAKIT Pinzon, Rizaldy
Jurnal Manajemen Pelayanan Kesehatan Vol 10, No 03 (2007)
Publisher : Jurnal Manajemen Pelayanan Kesehatan

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CLINICAL PATHWAY DALAM PELAYANAN STROKE AKUT: APAKAH PATHWAY MEMPERBAIKI PROSES PELAYANAN? Pinzon, Rizaldy
Jurnal Manajemen Pelayanan Kesehatan Vol 12, No 01 (2009)
Publisher : Jurnal Manajemen Pelayanan Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.083 KB)

Background: The stroke care pathway is a simple resourcethat provides the user with a summary of the key aspects ofcare that should be considered for people with stroke at anystage in their care. There is very limited study about the use ofclinical pathway in Indonesia.Aim: This study described the process of developing clinicalcare pathway and the trial of pathway for 50 patients withacute stroke.Method: The method of this study is after-before analysis.We compare the process and outcome of non haemorrhagicstroke patients before and after the pilot implementation of thepathway. The data was obtained randomly from the medicalrecord of stroke patients. The data was analyzed descriptively.Result: The data from 50 non haemorrhagic stroke patientsafter the pilot implementation of clinical pathway were comparedwith the data from previous year. The analysis showed thatthere are improvement in the tracing for stroke risk factors,swallowing assessment, nutritional consultation, and functionalstatus measurement after the pathway implementation. Thereare not significant reductions on the average length of stayand mortality rate between the two periods.Conclusion: Our study showed that clinical pathway isimproving the indicator of stroke care services. The furtherstudy for evaluating the effectiveness of stroke care pathwayin longer period is warranted.Keywords: clinical pathway, stroke, process of care, outcome

Tinjauan Neurobiology Gangguan Spektrum Autistik Pinzon, Rizaldy; Meliala, Lucas; Sutarni, Sri
Jurnal Kedokteran Meditek vol. 14 no. 37 Mei-Agustus 2006
Publisher : Jurnal Kedokteran Meditek

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Prognosis Tumor Otak Metastase Pinzon, Rizaldy
Jurnal Kedokteran Meditek vol. 15 no. 39 Januari-April 2007
Publisher : Jurnal Kedokteran Meditek

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Peran Kortikosteroid Sistemik Sebagai Terapi Adjuvan Nyeri Punggung pada Metastase Spinal Pinzon, Rizaldy
Jurnal Kedokteran Meditek vol. 15 no. 40 Mei-Agustus 2008
Publisher : Jurnal Kedokteran Meditek

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CRITICAL APPRAISAL OF EFFECTIVENESS OF ORAL FINGOLIMOD ON RELAPSING MULTIPLE SCLEROSIS Pinzon, Rizaldy Taslim; Sanyasi, Rosa De Lima Renita
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 14, No 2 (2017)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.00606

Oral fingolimod has been recently accepted as a treatment for relapsing Multiple Sclerosis (MS) by the Indonesian Food and Drug Administration. The number of MS patients is increasing in Indonesia. There is a critical need of systematically reviewing the new medication for both efficacy and safety. This review aimed to appraise the clinical evidences of oral fingolimod for the effective treatment of relapsing MS. We searched in Pubmed database. We limited our search to only articles that were in full text, published within the last 10 years, and in English. We used the Jadad scale to measure the quality of the evidences. We only found 3 trials, all conducted with randomized and double blind design. The three trials were: the FREEDOMS I, FREEDOMS II, and TRANSFORMS studies. The FREEDOMS studies compared with placebo, and the TRANSFORMS study compared with injectable interferon. All of the studies have good quality in methodology (Jadad scale 3). The results of the three studies showed the benefit of oral fingolimod in reducing MS relapse compared with placebo with relative risk reduction range from 48% to 54%, and also in reducing new lesions in T2 brain MRI with relative risk reduction range from 35% to 74%. Our critical appraisal found that oral fingolimod improved clinical outcomes. The availability of oral fingolimod in Indonesia makes it one of the options in treatment of MS relapse in Indonesia and has been demonstrated to be effective and safe with relatively small risk.

Risk factors of intracranial stenosis among older adults with acute ischemic stroke Pinzon, Rizaldy; Asanti, Laksmi; Sugianto, Sugianto; Widyo, Kriswanto
Universa Medicina Vol 28, No 1 (2009)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2009.v28.1-7

Intracranial large artery atherosclerosis is an important cause of stroke worldwide. Previous studies have shown that it is found more commonly in Asians. However, studies of intracranial stenosis in Indonesian stroke patients have been very few in number. The aim of this cross-sectional study was to determine the frequency and risk factors of intracranial stenosis in acute ischemic stroke. The data were obtained from 234 consecutive patients in the transcranial doppler (TCD) registry. Documentation of risk factors was performed systematically and for TCD sonography TD-DOP 9000 equipment with a 2-MHz probe was used for the examination of the intracranial circulation. The criteria of middle cerebral artery (MCA) stenosis used in this study were a peak systolic velocity (PSV) >140 cm/s or mean systolic velocity (MSV) >80 cm/s. For stenosis of the posterior circulation the criteria were PSV > 90 cm/s or MSV >60 cm/s. The data were obtained from 234 patients, and complete examinations were performed in 182 patients (77.7%). Ischemic stroke is the most common indication for performing TCD sonography. Stenosis was present in 38% of cases, with stenosis iof the anterior circulation being the more common. The most frequent risk factors were hypertension, dyslipidemia, and diabetes. Intracranial stenosis is common in stroke patients, in whom the risk factors are hypertension and diabetes.

Telaah kritis terapi risperidone untuk perbaikan perilaku pada gangguan spectrum autistik Pinzon, Rizaldy; Meliala, Lucas; Sutarni, Sri
Universa Medicina Vol 26, No 1 (2007)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2007.v26.39-45

Autisme adalah sindroma klinik yang ditandai oleh gangguan interaksi sosial, hambatan komunikasi verbal, dan keterbatasan aktivitas serta minat. Sampai saat ini, tidak ada terapi untuk autisme. Pengobatan farmakologis terutama ditujukan untuk mengurangi agresivitas, perilaku obsesif kompulsif, dan perilaku melukai diri sendiri. Telaah pustaka ini menunjukkan bahwa risperidone efektif dan aman untuk terapi tantrum, agresivitas, dan perilaku melukai pada anak-anak autistik. Namun risperidon tidak dapat memperbaiki kekurang anak dalam hal interaksi sosial dan komunikasi. Diperlukan penelitian lebih lanjut untuk mengembangkan pengobatan yang efektif untuk memperbaiki gangguan intarksi sosial dan komunikasi pada penderita autistik. Efektifitas yang menjanjikan dari resperidone ini memberikan harapan untuk mengobati anak-anak yang mengalami gangguan perilaku pada autisme.

PERANAN OBAT GOLONGAN STATIN TERHADAP LUARAN STATUS FUNGSIONAL PASIEN STROKE ISKEMIK BERULANG DI RUMAH SAKIT BETHESDA YOGYAKARTA Alexxander, Alexxander; Nugroho, Agung Endro; Pinzon, Rizaldi Taslim
Berkala Ilmiah Kedokteran Duta Wacana Vol 2, No 3 (2017): Berkala Ilmiah Kedokteran Duta Wacana
Publisher : Medical Faculty of Duta Wacana Christian University

Proporsi pasien yang menggunakan statin ketika pertama kali masuk rumah sakit dengan stroke iskemik berulang sangat meningkat dengan cepat. Tetapi masih menjadi kontroversi. Hal tersebut yang melatarbelakangi penelitian ini dilakukan untuk mengetahui peranan terapi statin dengan luaran status fungsional pada pasien stroke iskemik berulang di rumah sakit Bethesda Yogyakarta. Penelitian ini adalah penelitian analisis dengan metode retrospective cohort menggunakan data data rekam medis pasien. Sebagai sampel dipilih kelompok pasien stroke iskemik berulang, baik yang mendapat pengobatan dengan statin ataupun yang tidak mendapatkan pengobatan statin. Kemudian secara retrospektif diamati pengaruh penggunaan statin terhadap luaran status fungsional pasien. Jumlah subyek untuk masing masing kelompok adalah 77 pasien. Luaran baik ditandai dengan nilai mRS 0-3, sedangkan luaran buruk ditandai dengan 4-6. Lokasi penelitian adalah di rumah sakit Bethesda Yogyakarta. Penggunaan statin pada pasien stroke iskemik berulang dapat memberikan luaran status fungsional yang baik di RS Bethesda Yogyakarta (p = 0,022; RR=1,56; IK 95% = 1,056 – 2,305). Selain itu penelitian ini juga memberikan luaran sekunder yaitu variabel usia, GCS, dan kelemahan otot gerak memiliki hubungan bermakna terhadap luaran status fungsional pasien stroke iskemik berulang. Faktor prediktor untuk mendapatkan luaran status fungsional yang baik pada penelitian ini adalah pasien tanpa penggunaan antibiotik, GCS 13-15, penggunaan anti koagulan, pasien tanpa analgetik antipiretik, dan pasien dengan penggunaan anti platelet.Penggunaan statin pada pasien stroke iskemik berulang dapat memberikan luaran status fungsional yang baik di RS Bethesda Yogyakarta

Health Related Quality of Life and Residual Symptoms in Prostatic Surgical Treatment at Bethesda Hospital Yogyakarta: a Retrospective Study Krisna, Daniel Mahendra; Hariatmoko, Hariatmoko; Pinzon, Rizaldy Taslim
Althea Medical Journal Vol 4, No 3 (2017)
Publisher : Althea Medical Journal

Background: The incidence of Prostate Enlargement (PE) has been increasing over the years. The satisfaction towards the treatment result and life quality (QOL) improvement must be the key point of PE treatment. QOL is affected by many conditions, such as age, socioeconomic status, comorbid disease, and type of surgery. The objective of the study was to assess the QOL in PE patients post surgery, to explore the predictor factor, and to assess the satisfaction related to urinary functionality in the Indonesian context. Methods: A retrospective study was conducted and the subjects were all PE patients who underwent surgical treatment. EQ-5D-5L/EQ-VAS and Index Quality of Life (IQL) were used to assess the patientâs QOL & treatment satisfaction. The subjects were divided into several sub-groups based on age, type of surgery, comorbid condition, type of ward, funding source, histopathological result, and the year of treatment. The collected data wee analyzed using Mann-Whitney test, Kruskal Wallis test, or Chi-square test, Spearmanâs rho test and multiple linear regression. Results: All the 149 subjects were at the average age of 69.09 years . There were no significant statistical differences in QOL between age, comorbid conditions, and histopathology result. Health insurance (HI) was significantly associated with QOL. There were improvements of IQL subjects. The most symptoms remaining was frequency (47.4%).Conclusions: Life improvement must be the major purpose of PE therapy. The association between HI with QOL suggests that a better HI in developing countries can ensure a better quality of life outcome.

Co-Authors Agung Endro Nugroho Agung Wiwiek Indrayani Agustinus Rudolf Phyma, Agustinus Rudolf Al Jody, Abraham Alexxander Alexxander, Alexxander Alfi Yasmina Amboro, Wisnu Angela, Angela Ardiani, Birgitta Lisbethiara Daniel Mahendra Krisna, Daniel Mahendra Endarti, Dwi Esdras Ardi Pramudita, Esdras Ardi Firmansyah, Ferdy Fransiska Theresia Meivy Babang, Fransiska Theresia Meivy Gelgel, Putu Clara Shinta Gunawan, Jimmy Indarto Hana, Jesi Prilly Hardi Astuti Witasari Hariatmoko, Hariatmoko I Putu Eka Widyadharma Ika Puspitasari Iwan Dwiprahasto Jarir At Thobari Jesisca, Fransiscus Buwana Jesisca, Jesisca Kartika, Yolanda Dyah Kristin, Erna Kriswanto Widyo, Kriswanto Laksmi Asanti, Laksmi Lucas Meliala Mugiono, Iroen Muslimah Muslimah Nugraha, Boya Padma, Radha Govinda Pratiwi, Woro Rukmi Priskila, Loury Rendra, Andreas K. Renita Sanyasi, Rosa De Lima Renita Sanyasi, Rosa De Lima Rosa De Lima Renita Sanyasi, Rosa De Lima Renita Setyawan, Irfanianta Arif Sri Sutarni Sugianto Sugianto Susi Susanti Thomas Eko Purwata, Thomas Eko Tri Murti Andayani Trijayanti, Christiana Vania Rau, Chiquita Putri Wijono, Andre Dharmawan Y, Yudiyanta Zalukhu, Marta Lisnawati

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