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All Journal AGRISAINS AL KAUNIYAH Proceedings of KNASTIK Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati JURNAL PEMULIAAN TANAMAN HUTAN Biology, Medicine, & Natural Product Chemistry Pro-Life Edumatsains Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Jurnal Pembelajaran dan Biologi Nukleus Sciscitatio : Journal for Biological Science Jurnal Agrohut
Aniek Prasetyaningsih
Program Studi Biologi, Fakultas Bioteknologi, Universitas Kristen Duta Wacana
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Engineering Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Other

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Journal : Sciscitatio : Journal for Biological Science

 1 
Potency of Citrus reticulata Peel Extract as Active Compound of NonAlcohol Based Gel Hand Sanitizer Santoso, Julyana Dika; Prasetyaningsih, Aniek; Madyaningrana, Kukuh
SCISCITATIO Vol 1 No 2 (2020): Volume 1, Number 2, July 2020
Publisher : Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/sciscitatio.2020.12.32

Abstract

Hand sanitizer is nowadays known as a part of one’s personal hygiene kit because of its practical use andeffectivity against skin microbes, such as Staphylococcus aureus. The common commercial hand sanitizers are madefrom alcohol which may have negative side effect like skin irritation. Utilization of active compounds from a plantthat has antibacterial compounds might be applied to the substitution of alcohol in the formulation of hand sanitizer.In this study, phytochemical compounds from Citrus reticulata and Citrus aurantifolia peel extracts were testedqualitatively and their antibacterial acitivity on Staphylococcus aureus were tested using disk diffusion method. Theresults showed that Citrus reticulata peel extract at the concentration of 70% was the most effective concentration ininhibiting Staphylococcus aureus. This certain concentration of Citrus reticulata peel extract was then chosen in the gelhand sanitizer formulation. Application of gel hand sanitizer with Citrus reticulata peel extract as its active compoundon the hands of respondents were also observed to inhibit bacterial growth. The use of peel extracts from Citrusspp, especially from Citrus reticulata might be potential in the formulation of non-alcohol based gel hand sanitizer.
Antibacterial Activity of Lime Peel and Lemongrass Extract as Active Ingredients for Spray Hand Sanitizer Djima, Elza Gitaa Eirene Djima; Prasetyaningsih, Aniek; Madyaningrana, Kukuh
SCISCITATIO Vol. 2 No. 1 (2021): Volume 2, Number 1, Januari 2021
Publisher : Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hand sanitizers are widely used as an alternative way to maintain hand hygiene from the presence ofpathogenic bacteria, such as Staphylococcus aureus. In general, excessive use of alcohol as the main ingredientin hand sanitizers might cause skin irritation. Utilizing antibacterial activity of plants as a component in handsanitizer could be used as a substitution for alcohol. The aim of this study was to determine the potentialantibacterial activity of lime peel and lemongrass extracts as active ingredients for hand sanitizer. Methodused in this research included extraction using maceration, qualitative phytochemical test, antibacterialassay, and formulation of spray hand sanitizer and quality test of spray hand sanitizer. In this study alkaloid,flavonoid, saponin, tannin and terpenoid were found as phytochemical content of lime peel, while lemongrassextract contain fla vonoid, tanin, saponin and steroid. Compared to lemongrass extract, lime peel extract withconcentration 40%showed the optimum inhibition zone of S. aureus and chosen as active ingredient in sprayhand sanitizer formulation. Formulated spray hand sanitizer with lime peel extract was able to inhibit thegrowth of S. aureus bacteria on hand palm.
Pemanfaatan Senyawa Metabolit Sekunder Ekstrak Eter Diadema setosum dari Pantai Kukup dan Pantai Sundak Gunungkidul sebagai Antiinflamasi Tiffany, Yollanda; Prasetyaningsih, Aniek; Aditiyarini, Dwi
SCISCITATIO Vol. 2 No. 2 (2021): Volume 2, Number 2, Juli 2021
Publisher : Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/sciscitatio.2021.22.68

Abstract

Bulu babi atau landak laut merupakan hewan laut yang tergolong dalam kelas Echinoidea. Kelompok hewan dari kelas Echinoidea mempunyai kemampuan menghasilkan metabolit sekunder yang memiliki efek farmakologis seperti antibakteri, antitumor dan kanker, antioksidan, dan antiinflamasi. Salah satu metabolit sekunder dari yang dihasilkan oleh hewan dari kelompok Echinoidea adalah Ovothiol-A yang berpotensi sebagai antiinflamasi. Penelitian ini bertujuan untuk mempelajari metabolit sekunder dari Diadema setosum yang berasal dari Pantai Selatan Gunungkidul dan studi potensinya sebagai antiinflamasi. Hasil uji KLT dan FTIR menunjukkan bahwa spesies Diadema setosum sebagai salah satu anggota Echinoidea diduga mengandung senyawa Ovothiol-A pada bagian organ maupun cangkangnya. Senyawa diduga sebagai Ovothiol-A yang dihasilkan oleh D. setosum memiliki kemampuan antiinflamasi yang ditunjukkan oleh penyempitan luka pada mencit yang diberi perlakuan ekstrak bagian organ (100%) D.setosum dengan rata-rata penyempitan luka 0,44±0,256 mm/hari. Hasil dari penelitian ini menunjukkan bahwa ekstrak D. setosum memiliki senyawa Ovothiol-A yang dapat berfungsi sebagai antiinflamasi. Ekstrak D. setosum bagian organ memiliki kemampuan antiinflamasi yang lebih baik.
Co-Authors Adonia Felma Mosse Angelia Astria AYPBC Widyatmoko Catarina Aprilia Ariestanti Devi Sonti Sibarani Djima, Elza Gitaa Eirene Djima Djoko Rahardjo Djoko Rahardjo Dwi Aditiyarini Dwi Adityarini Elisabet Suharti Soleman Elsih Dian Ariningsih Kania Apenta Olisvelos Kisworo Kisworo Kukuh Madyaningrana Lavenia, Jovita Maria Grasela Kase Meilani Apra Nurlia Widayanti Ratih Restiani Santoso, Julyana Dika Seta Nurhayati Mularum Setya Harianto Tara Inastu Kandarp Tiffany, Yollanda Vinsa Cantya Prakasita Willy Sudiarto Raharjo Wulan Krista Waty