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All Journal AGRISAINS AL KAUNIYAH Proceedings of KNASTIK Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati JURNAL PEMULIAAN TANAMAN HUTAN Biology, Medicine, & Natural Product Chemistry Pro-Life Edumatsains Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Jurnal Pembelajaran dan Biologi Nukleus Sciscitatio : Journal for Biological Science Jurnal Agrohut
Aniek Prasetyaningsih
Program Studi Biologi, Fakultas Bioteknologi, Universitas Kristen Duta Wacana
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Engineering Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Other

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Journal : Pro-Life

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Potensi Minyak Sereh Wangi (Cymbopogon nardus) sebagai Antibakteri terhadap Propionibacterium acnes dan Staphylococcus aureus pada Sediaan Gel Antijerawat Kania Apenta Olisvelos; Dwi Aditiyarini; Aniek Prasetyaningsih
Jurnal Pro-Life Vol. 10 No. 1 (2023): Maret
Publisher : Program Studi Pendidikan Biologi Fakultas Keguruan dan Ilmu Pendidikan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33541/jpvol6Iss2pp102

Abstract

Acne can be caused by the bacteria Propionibacterium acnes and Staphylococcus aureus. One way to treat acne is to use antibiotics. However, this can create resistance. In this study, citronella oil will be formulated into an anti-acne gel preparation with various concentrations of 10%, 15% and 20%. The study began with distillation of citronella oil and analysis and identification of compounds. Then the gel was made by mixing citronella oil in the HPMC gel base and then the gel preparation was tested for antibacterial activity by the disc diffusion method and physical preparation tests included organoleptic tests, pH measurements, viscosity tests, homogeneity tests, dispersion tests, gel stability tests. Based on the results of compound analysis using GC-MS, citronella oil contains geraniol (55.05%). Of the three formulations, the preparation that has good gel physical properties based on its physical properties is F2 with 15% citronella oil content. In the antibacterial test, the results showed that citronella oil gel had the ability to inhibit Propionibacterium acnes and Staphylococcus aureus with the most optimal formulation being F2 with an average inhibition of 1.5 cm.
Co-Authors Adonia Felma Mosse Angelia Astria AYPBC Widyatmoko Catarina Aprilia Ariestanti Devi Sonti Sibarani Djima, Elza Gitaa Eirene Djima Djoko Rahardjo Djoko Rahardjo Dwi Aditiyarini Dwi Adityarini Elisabet Suharti Soleman Elsih Dian Ariningsih Kania Apenta Olisvelos Kisworo Kisworo Kukuh Madyaningrana Lavenia, Jovita Maria Grasela Kase Meilani Apra Nurlia Widayanti Ratih Restiani Santoso, Julyana Dika Seta Nurhayati Mularum Setya Harianto Tara Inastu Kandarp Tiffany, Yollanda Vinsa Cantya Prakasita Willy Sudiarto Raharjo Wulan Krista Waty