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Expression of Brain-Derived Neurotrophic Factor in the Brain of Depressed Mice: Systematic Literature Review Nur Azizah AS; Lysa Veterini; Hafid Algristian; Hotimah Masdan Salim
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 2 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i2.6354

Abstract

Chronic stress exposure plays a role as a risk factor for depression. In chronic stress, there is prunning of nerve cell dendrites so that depression becomes irreversible. Depression is caused by low serotonin (5-HT2) neurotransmitters in the postsynaptic cleft. Recent findings in experimental animals indicate that serotonergic preparations are required to increase serotonin levels in the synapse opening, thereby triggering the formation of new dendrites to make depression reversible. The different results when these preparations create resistance in cases of chronic depression and actually increase the risk of uncomfortable and even fatal side effects with long-term use. This Systematic Literature Review uses the PubMed and Google Scholar databases for the period 2015-2020. A total of 322 articles at the beginning of identification and those that met the inclusion criteria in this study were six articles. The results of data extraction showed that the depression condition caused by various stressors resulted in BDNF levels in the hippocampus decreased significantly by p≤0.005. Based on the literature study, it was concluded that in depressive conditions, BDNF levels in the brain decreased.
A Case Report: Paranoid Schizophrenia With Stressing Point Screening For Paranoid Schizophrenia Prognosis Andik Ferdiantoro; Nur Azizah AS; Hafid Algristian
Jurnal Medis Islam Internasional Vol 3 No 1 (2021): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v3i1.2127

Abstract

Background: Schizophrenia is a psychiatric disorder characterized by decrease or inability to communicate, reality disorders, namely hallucinations and delusions, cognitive impairment and difficulty to carry out daily activities. Paranoid schizophrenia is one of the most common types of schizophrenia and its has good prognosis among other types of schizophrenia. But the prognosis decision making for paranoid schizophrenia is influenced by the following factors: prepsychotic personality, acute or chronic, type of schizophrenia, age, administration of medication, presence or absence of precipitating factors, and heredity. Objective: This study aims to determine the prognosis of paranoid schizophrenia in case is using the factors above. The case study is based on the examination of patients in the outpatient psychiatric clinic of the Islamic Hospital of Jemursari Surabaya who have received the patient's consent. Methods: The method of diagnosis uses a pocket book for the diagnosis of mental disorders PPDGJ-III and DSM-V. Result: The results are showed that is paranoid schizophrenic patients with a poor prognosis (dubia ad malam). Conclusion: All of paranoid schizophrenia have not being a good prognosis (dubia ad bonam) because it is influeced by several factors, namely prepsychotic personality, acute or chronic, type of schizophrenia, age, administration of medication, presence or absence of trigger factors, and heredity. Keywords: Paranoid Schizophrenia, Prognosis of Paranoid Schizophrenia
The Role of Religion and Spirituality in Managing Residual Schizophrenia: Article Review Aufar Zimamuz Zaman Al Hajiri; Nur Azizah AS; Hafid Algristian
Jurnal Medis Islam Internasional Vol 3 No 1 (2021): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v3i1.2493

Abstract

Background: Residual Schizophrenia is a chronic condition of schizophrenia characterized by a history of leastwise one psychotic episode with more prominent negative symptoms. Schizophrenic patients who have persistent psychotic symptoms and patients with residual schizophrenia should receive adequate pharmacotherapy, and may consider additional cognitive therapy, as it has been shown to help reduce relapse rates, reduce psychotic symptoms, and improve or stabilize the patient's mental state. Objective: To determine the role of religion and spirituality in the management of patients with residual schizophrenia.Methods: The design of this research is a literature review or library review, which is a systematic, direct, and reproducible research method by identifying, evaluating, and synthesizing published research.Result: Patients with a higher level of religion or spirituality or their strong personal belief system are more likely to use positive appraisal to deal with their illness or problem which includes giving positive meaning to the situation and being optimistic. Conclusion: The presence of religion and spirituality help the coping mechanisms of residual Schizophrenia patients which also improves patient management, accelerate the healing process, and increases QOL of patients. Keywords: Spirituality, Religion, Residual Schizophrenia.
Pencegahan Perundungan untuk Mendukung Zero Violance Education di Lingkungan Pondok Pesantren Hafid Algristian; Nur Azizah AS; Fifi Khoiru Fithriyah; Khamida Khamida; Nur Hidayah; Devy Yahya
PROSIDING SEMINAR NASIONAL PENGABDIAN KEPADA MASYARAKAT UNIVERSITAS NAHDLATUL ULAMA SURABAYA Vol. 1 No. 1 (2022): Prosiding Seminar Nasional Pengabdian Kepada Masyarakat : Perguruan Tinggi Meng
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (815.99 KB) | DOI: 10.33086/snpm.v1i1.809

Abstract

Beberapa kasus perundungan di pondok pesantren yang menjadi isu nasional ini menggambarkan bahwa pesantren bukanlah lingkungan pendidikan yang sepenuhnya bebas dari perilaku kekerasan. Pesantren dianggapsebagai pusat pendidikan keislaman yang seharusnya menjadi model zero violance education. Peran serta banyak pihak sangat dibutuhkan terutama untuk memberikan edukasi secara berkelanjutan guna mencegah kejadian serupa di kemudian hari. Kegiatan pengabdian masyarakat yang dilaksanakan di tiga pondok pesantren di Jawa Timur ini (PP. Al Hikam, Bangkalan; PP. KHA. Wahid Hasyim, Bangil; dan PP. Zaniul Hasan, Genggong) bertujuan memberikan edukasi tentang perundungan kepada santri pondok pesantren. Kegiatan ini dilaksanakan secara daring melalui webinar. Dampak kegiatan ini dinilai menggunakan pre dan post test (google form) pada peserta. Pengumpulan pre dan post test membutuhkan waktu lebih lama karena santri menggunakan ponsel guru secara bergantian. Didapatkan peningkatan skor post test dibandingkan pre test. Disimpulkan bahwa wawasan santri tentang perundungan lebih baik dibandingkan sebelum diadakan webinar. Kegiatan ini dapat menjadi model edukasi di kemudian hari, sehingga diharapkan dapat menjadi upaya pencegahan perilaku perundungan, untuk mendukung terwujudnya zero violance education di lingkungan pondok pesantren.
Sosialisasi Program Vaksinasi COVID-19 untuk Mendukung Pemulihan Ekonomi Kerakyatan di Pondok Pesantren Assalafi Al-Fitrah Surabaya Nur Azizah AS; Renata Alya Ulhaq
PROSIDING SEMINAR NASIONAL PENGABDIAN KEPADA MASYARAKAT UNIVERSITAS NAHDLATUL ULAMA SURABAYA Vol. 1 No. 1 (2022): Prosiding Seminar Nasional Pengabdian Kepada Masyarakat : Perguruan Tinggi Meng
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (961.71 KB) | DOI: 10.33086/snpm.v1i1.838

Abstract

Corona virus Disease 2019 (COVID-19) merupakan penyakit menular yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Tidak hanya kesehatan, pandemi COVID-19 ini berdampak juga terhadap ekonomi. Pondok pesantren merupakan center of exellence dalam aspek moralagama, moral-kesehatan, maupun moral-ekonomi bagi masyarakat sekitar ponpes. Kegiatan pengabdian pada masyarakat ini berfokus pada peningkatan pengetahuan tentang vaksinasi COVID-19 di lingkunganPondok Pesantren Assalafi Al Fithrah Surabaya. Kegiatan ini bertujuan mendukung pemulihan kesehatan dan pemberdayaan ekonomi masyarakat di sekitar pondok pesantren yang tidak tersentuh programprogram pemerintah. Kegiatan ini dilaksanakan secara daring dalam bentuk webinar oleh tim Unit Penelitian dan Pengabdian Masyarakat (UPPM) dan Departemen Ilmu Kedokteran Masyarakat-Kedokteran Pencegahan (IKM-KP) Universitas Nahdlatul Ulama Surabaya. Hasil kegiatan menunjukkan bahwa para santri dan pengurus mendapat pengetahuan baru tentang urgensi vaksinasi COVID-19, efektivitas, efek samping vaksinasi COVID-19, dan mendorong masyarakat pesantren untuk mau melaksanakan vaksinasi COVID-19 untuk mendukung pemulihan ekonomi masyarakat.
Pengaruh Edukasi Kesehatan Meditation Healing Exercise terhadap Peningkatan Pengetahuan Penderita Diabetes Mellitus dalam Upaya Menjadi Sehat Mandiri Rahmadaniar Aditya Putri; Nurul Kamariyah; Siti Nur Hasina; Iis Noventi; Nur Azizah AS
Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Vol 12 No 4 (2022): Jurnal Ilmiah Permas: jurnal Ilmiah STIKES Kendal: Oktober 2022
Publisher : Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.287 KB)

Abstract

Penderita Diabetes Mellitus memiliki kerentanan mengalami gangguan vaskular sehingga aliran sirkulasi darah tidak lancar, rentan mengalami gangguan ekstremitas kaki yang bermanifestasi menjadi sumbatan pada pembuluh  darah atau gangguan perfusi jaringan perifer,  ulkus  bahkan  amputasi sehingga perlu adanya pendidikan kesehatan dalam upaya pencegahan resiko gangguan perfusi jaringan perifer. Tujuan penelitian ini untuk mengetahui pengaruh Pendidikan Kesehatan Terapi buerger allen exercise terhadap peningkatan pengetahuan penderita diabetes mellitus dalam upaya menurunkan resiko gangguan perfusi perifer. Metode penelitian yang digunakan dalam penelitian ini adalah metode kuantitatif dengan jenis pre-eksperimental tipe one-group pretest-posttest dengan jumlah sampel sebanyak 68 orang yang diambil menggunakan Teknik total sampling. Hasil penelitian ini Tmenunjukkan bahwa tingkat pengetahuan responden pada penelitian ini sebelum diberikan intervensi didapatkan Sebagian besar 51,6% berpengetahuan kurang. Dan setelah diberikan Pendidikan Kesehatan didapatkan Sebagian besar 69,1% berpengetahuan baik. Hasil uji analisis Wilcoxon sign rank test didapatkan nilai p adalah 0,001. Terdapat pengaruh Pendidikan Kesehatan terapi Buerger Allen exercise terhadap peningkatan pengetahuan penderita Diabetes mellitus dalam upaya menurunkan resiko gangguan perfusi jaringan perifer. Pemberian Pendidikan Kesehatan sangat efektif diberikan bagi penderita Diabetes Mellitus terutama berkaitan dengan pencegahan komplikasi.
Competency of Muslim Doctors Mutmainnah; Hafid Algristian; Nur Azizah
Jurnal Medis Islam Internasional Vol 4 No 1 (2022): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i1.2242

Abstract

Background: In the medical profession, a doctor will often be faced with situations of uncertainty to make the right decisions and diagnoses. In this case, making a Muslimdoctor to be able to have a good impact on patients. A Muslim doctor is expected to be able to implement professional and reliable competencies in the future. In facing the future, with all the challenges in the medical world, ethical principles, moral values and good competence are needed in order to be able to provide the best health services by minimizing risks and side effects, and prioritizing greater benefits so as not to harm doctors as service providers, and patients as recipients of health services.Objective: This study aims to learn more about the definition and principles of medical ethics, muslim doctor competence, and Islamic medical moral values.Methods: The article source in the same field was compiled. Through a several literature search of reputable journals wich maximum published in the past 10 years.Result: Several article was found, and all the article said the moral values in Islamic medicine are closely related to the personality of Muslim Doctors.Conclusion: The guidelines for islamic medical ethics as muslim are Qur’an, Hadist, Ijma’ and Qiyas. The four main moral principles for be a good doctor are the principle of autonomy, beneficence, non-maleficence, and the principle of justice. The competence of Muslim doctors has a close relationship with ethical principles, moral values, and law. The moral values of muslim doctors includes self-awareness, such as awareness of fitrah (inne-rself) and social awareness as caliph (external-self-awareness).
Pengenalan Gangguan Makan pada Remaja Perempuan Beserta Faktor Risikonya Nur Azizah AS; Achmad Yarziq Mubarak; Yunik Windarti; Niken Adiba Nadya; Khadijah Khairul Bariyah
PROSIDING SEMINAR NASIONAL PENGABDIAN KEPADA MASYARAKAT UNIVERSITAS NAHDLATUL ULAMA SURABAYA Vol. 3 No. 1 (2023): Prosiding Seminar Nasional Pengabdian Kepada Masyarakat : MEMAKSIMALKAN POTENSI
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar belakang: Lingkungan pesantren memiliki potensi besar dalam pengembangan umat Islam untuk mempersiapkan sumber daya manusia yang tangguh, mandiri, serta menerapkan nilai-nilai Islam dalam kehidupan sehari-hari. Namun lingkungan pesantren yang sebagian besar terdiri dari santri berusia remaja yang dianggap sebagai masa-masa pencarian identitas diri menyebabkan khususnya para remaja perempuan sangat menjaga penampilan fisiknya dan berisiko memiliki perspektif yang salah tentang body-image yang ideal dan mengalamai gangguan psikiatrik salah satunya yaitu gangguan makan. Tujuan: Tujuan dari kegiatan ini adalah untuk meningkatkan pemahaman para santriwati PP. KHA Wahid Hasyim Bangil terkait gangguan makan beserta faktor risikonya. Metode: Metode yang dilakukan adalah dengan melakukan penyuluhan kepada mitra binaan yaitu santriwati PP. KHA Wahid Hasyim Bangil. Sebelum penyuluhan, dilakukan pre-test selama 10 menit untuk para peserta. Dilanjutkan dengan sesi penyuluhan dan tanya jawab kurang lebih selama 60 menit, dan setelahnya dilakukan post test selama 10 menit. Hasil pre-test dan post-test selanjutnya dinilai dan dilakukan pengolahan data dan evaluasi. Hasil: Hasil uji Wilcoxon menunjukkan nilai p-value 0,002 sehingga nilai sig < 0,05 yang menunjukkan adanya perbedaan signifikan terkait data pre-test dan post-test. Hal ini diartikan bahwa adanya peningkatan wawasan, pemahaman, dan adanya perubahan sikap kepada para peserta santriwati PP. KHA Wahid Hasyim Bangil dari sebelum dan pasca mengikuti sesi penyuluhan. Kesimpulan: Kegiatan pengabdian masyarakat tentang pengenalan gangguan makan pada remaja perempuan beserta faktor risikonya di PP. KHA Wahid Hasyim Bangil telah memberikan pengaruh yang signifikan kepada para peserta yaitu berupa peningkatan wawasan perihal topik gangguan makan.
Case Study : Prognosis of Recurrent Depressive Disorder with Somatic Symptoms Firda Nur Laila; Hafid Algristian; Nur Azizah
Jurnal Medis Islam Internasional Vol 5 No 1 (2023): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i1.4454

Abstract

Introduction: Depression is a common disease worldwide, with more than 264 million people affected. Especially if it lasts a long time and is of moderate or severe intensity, depression can be a serious health condition. Depression can cause affected people to suffer greatly and function poorly at work, at school, and in the family. At its worst, depression can lead to suicide. In general, the good prognosis of depressive episodes can be achieved as well as good response to treatment and early interventions, but with the absence of any other complication such as psychotic symptoms and somatic complaints. This paper discusses the prognosis of recurrent depressive disorders with somatic complaints through a case study. Case: Male 23 years old complained of headaches that did not improve with pain medication and often recurred for two weeks, feels tingling and heavy in the back, worsening at night, interfere with the patient's daily activities and sleep in the night. These depressive symptoms have recurred since the patient was 19 years old. The patient experienced repeated stress due to arguments between his parents who were often involved in verbal abuse. The patient's prognosis is analyzed using several aspects according to Maramis prognosis analysis, including age, premorbid personality, type of disorder, course of treatment, hereditary factors, and the presence/absence of precipitating factors. Discussion: According to the course of the disease, the patient experienced recurrent depression since the age of less than 20 years, with somatic symptoms currently accompanying his depressive disorder. The patient experienced repeated recurrences even though he was stated to have improved by the treating doctor, which indicates that the patient's stress management was inadequate. The patient is currently experiencing a skin disorder that worsens his pessimistic feelings and is receiving SSRI antidepressants to improve his depressive symptoms. Based on the analysis of the course of the disease, the prognosis for depressive disorders in patients is poor, or dubia ad bonam. Conclusions: Recurrent depressive disorders involving younger ages, complications such as somatic symptoms, suboptimal social support, inadequate coping mechanisms, will worsen the prognosis of depression even after receiving adequate treatment