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All Journal BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan) Jurnal Pendidikan Kimia (JPKim) EKSAKTA : Jurnal Penelitian dan Pembelajaran MIPA Jurnal Pembelajaran dan Biologi Nukleus Jurnal Sains dan Teknologi Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi Herbal Medicine Journal Borneo Journal of Pharmacy
Kasta Gurning
Sekolah Tinggi Ilmu Kesehatan Senior Medan, Medan 20141, Indonesia
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Public Health Transportation Veterinary

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Journal : Jurnal Sains dan Teknologi

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Aktivitas Antibakteri Ekstrak Etanol Daun Pepaya (Carica papaya Linn.) Terhadap Bakteri Pseudomonas aeruginosa Nasri Nasri; Vera Estefania Kaban; Kasta Gurning; Hariyadi Dharmawan Syahputra; Denny Satria
INSOLOGI: Jurnal Sains dan Teknologi Vol. 1 No. 3 (2022): Juni 2022
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (376.277 KB) | DOI: 10.55123/insologi.v1i3.438

Abstract

Pseudomonas aeruginosa is a Gram-negative bacterium that can cause nosocomial infections. The use of antibiotics in the treatment of non-adherent P. aeruginosa infections increases the risk of antibiotic resistance. Efforts to find new antibiotic compounds from plants continue to be carried out. Papaya leaves are widely spread among the public, which are often used as ingredients for vegetables and have antibacterial potential because they contain papain enzymes and a class of flavonoid compounds. The purpose of this study was to analyze the antibacterial activity of the ethanol extract of papaya leaves (Carica papaya Linn.) against P. aeruginosa by finding the value of the Minimum Inhibitory Concentration (MIC) and calculating the index activity value against the positive control. The method used in this research is Kirby-Bauer (disc diffusion method) with several variations of the test concentration. The results showed that the diameter of the inhibition zone at a concentration of 500 mg/mL was in the strong category with an inhibition zone diameter of 10.87 ± 0.06 mm. MIC at a concentration of 3.125 mg/mL. The index activity value was greatest at a concentration of 500 mg/mL with a value of 0.668. So it can be concluded that the ethanol extract of papaya leaves (Carica papaya Linn.) has inhibitory activity against Pseudomonas aeruginosa.
Formulasi Sediaan Lip Cream Ekstrak Daun Miana (Coleus scuatellariodes [L] Benth.) sebagai Pewarna Alami Vera Estefania Kaban; Nasri Nasri; Kasta Gurning; Hariyadi Dharmawan Syahputra; Zulmai Rani
INSOLOGI: Jurnal Sains dan Teknologi Vol. 1 No. 4 (2022): Agustus 2022
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v1i4.719

Abstract

Miana leaf (Coleus scutellarioides L.) is a plant that contains anthocyanins that can provide certain dyes. The purpose of this study was to formulate miana leaf extract in lip cream preparations as a natural dye. The research method includes the manufacture of ethanol extract of miana leaves (Coleus scutellarioides L.) by maceration method. The extract formulas used were 25%, 50%, and 75%. The tests carried out included organoleptic tests, homogeneity tests, physical tests, pH tests, irritation tests and color preference tests. The results of the lip cream preparation, the results of the organoleptic examination were declared to have a semi-solid dosage form, distinctive odor and varied colors F1 pink F2 purplish red, F3 blackish red, homogeneity test results were declared homogeneous, stability test results showed that the preparation did not change shape, color and the odor of the preparation for 14 days of storage, the results of the pH test showed that the preparation was still within the permissible pH range on the use of the skin, the test results were declared non-irritating. Miana leaf ethanol extract can be made as a colorant in lip cream preparations.
Co-Authors Bayu Cakra Buana Chyntia Glori Tania Dameria Siahaan Denny Satria Esther Siringo ringo Hariyadi Dharmawan Syahputra Helen Anjelina Simanjuntak Helen anjelina simanjuntak Iksen Indah Yani Tambunan Mastiur Julianti Maya Amelia Sinaga Nasri Nasri Nasri Nasri Risanti Situmorang Saronom Silaban Sifikal Lumbangaol Syahrina Syahrina Vera Estefania Kaban Verawati Br. Sinaga Vivi Asfianti Zulmai Rani