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Evaluation of surface modified PLLA-collagen hollow fiber as vascular graft Mayasari, Dita Ayu; Widiyanti, Prihartini; Rudyardjo, Djony Izak
MEDISAINS Vol 17, No 2 (2019)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v17i2.5259

Abstract

Background: Cardiovascular disease as the first silent killer in the world is related to atherosclerosis plaque. Coronary artery bypass grafting as a gold standard for severe atherosclerosis needs alternative materials to replace the narrowed artery due to plaque. PLLA is one of the biodegradable polymers which is suitable for the vascular graft, but some of its weaknesses should be addressed.Objective: The aim of this research is to improve PLLA characteristics for a vascular graft candidate by using collagen and chitosan.Methods: This study was an experimental study that consisted of two steps, preparation of hollow fiber and evaluation of its characteristic. This research evaluated the effect of chitosan concentration against cytotoxicity and hemocompatibility using MTT assay and hemolytic test.Results: The result showed that chitosan could improve the biological characteristics of hollow fiber PLLA-collagen, non-toxic, and non-hemolytic.Conclusions: There is a good effect on the biological characteristics of PLLA-Collagen hollow fiber by adding chitosan on the surface of PLLA-Collagen hollow fiber.
Synthesize and Characterization of Aluminum Oxide (Al2O3) Nanoparticle from Aluminum Waste for Nano fluid Application Darmawan Darmawan; Dani Gustaman Syarif; Djony Izak Rudyardjo
Indonesian Applied Physics Letters Vol. 1 No. 1 (2020): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iapl.v1i1.21330

Abstract

The research of Synthesis and Characterization of Aluminum Oxide (Al2O3) Nanoparticle from Aluminum Waste for Nanofluids has been done. The purpose from this research are knowing the influence of heating temperature tonanoparticle Al2O3 forming and the influence of composition to physico-chemical characteristic of nanofluids Al2O3.The heating temperature variation that that use of 6000C, 7000C, and 8000C. While the composition variation that use of 0.1 gram, 0.2 gram, 0.3 gram, and 0.5 gram. Aluminium Oxide nanoparticle were synthesized by heating Al(OH)3 as precursor derived from aluminum waste precipitation. Aluminum Oxide nanoparticle were suspended with 100 ml of Aquades and dispersed with ultra sonicated to produce Al2O3 nanofluids. Al2O3 nanoparticle has been obtained doing the characterization are the test of XRD (X-Ray Diffraction), SAA (Surface Area Analyzer), Density, Viscosity, CHF (Critical Heat Flux) and Zeta Potential. XRD data showed that the crystallized peak from Al2O3 nanoparticle are gamma alumina with the crystallite size of 6,5 nm (Debye-Scherrer Method). The Surface Area test result from Al2O3 nanoparticle is 149,98 m2/gram and obtained shape of11 nm. According zeta potential data, Nano fluids were stable at pH of 6,3 with zeta potential of 36,70 - 43,53 mV. The density test result obtained with the highest value about 1,503 g/cm3, The viscosity test of 0.92 mPa.s at the composition variation of 0.5 gram. The Nano fluids of the surface decreased 40% after 7 days. CHF test result of Al2O3 nanofluids obtained enhancement about 53,21% at the composition variation of 0.5 gram compared to that of Aquades.
Degradation and Corrosion of Biodegradable Metal Zn-xCa Adri Supardi; Miftachul Nur Afifah; Djony Izak Rudyardjo
Indonesian Applied Physics Letters Vol. 1 No. 2 (2020): Desember
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iapl.v1i2.23444

Abstract

Zn-based biodegradable metals (BMs) are considered as new potential in osteosynthetic implant devices. In this study Ca, which acts as an essential element in the human body, is used to improve the rate of Zn degradation and corrosion. The alloy was synthesized using the powder metallurgy method with two different processes: cold pressing followed by sintering (CP-S) and hot isostatic pressing (HIP). Microstructure properties, as well as in vitro degradation and corrosion were studied to determine the effect of adding Ca. Variations in the sample consist of Zn-0.5Ca, Zn-1Ca, Zn-1.5Ca and Zn-2Ca. The results and analysis of test data show that the addition of Ca increases the rate of corrosion and degradation of the materials. Better bonding and microstructure properties are obtained in Zn-2Ca samples which form CaZn13 phases and small porosity. As for the HIP process, a better microstructure is obtained compared to CP-S.
The Effect of Various Milling Time Duration On The Characteristic of Glass Ionomer Cement (GIC) with The Addition of Liquid Pmve-Ma Djony Izak Rudyardjo; Jan Ady; Aditya Budi Fauzi
Indonesian Applied Physics Letters Vol. 1 No. 2 (2020): Desember
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iapl.v1i2.23445

Abstract

A study entitled The Effect of Milling Time Duration on the Characteristics of Glass Ionomer Cement (GIC) Dental Cement with the Addition of Liquid PMVE-MA aims to determine the effect of milling time duration on the physical and mechanical properties of Glass Ionomer Cement, and to determine the optimum milling time duration in order to obtain GIC dental cement with the best characteristic to be applied as a dental restoration material. The duration of the milling time was 80 minutes, 90 minutes, 100 minutes, and 110 minutes. After the milling process, the next process was sintered at a temperature of 1200 for 1 hour to form Powder Glass Ionomer. Then Powder Glass Ionomer was added with Poly Methyl Vinyl Ether-Maleic Acid (PMVE-MA) to form a paste. The mixed paste was then formed. Sample characterization was the density test, the compressive strength test, and the vickers hardness test. The results of the density test obtained the highest value of 1.683 gram / cm3, the compressive strength test of 71.841 MPa, and the highest value of the hardness test of 92.3 Kg / mm2. These results increased as the increasing milling time duration up to 110 minutes.
Synthesis and Characterization of Nickel-Based Superalloy Materials for Manufacturing Aircraft Turbine Blades Rezza Ruzuqi; Drs. Djony Izak Rudyardjo, M.Si.; Andi Hamim Zaidan, S.Si., M.Si., Ph.D.
Indonesian Applied Physics Letters Vol. 2 No. 2 (2021): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iapl.v2i2.31557

Abstract

The research has been conducted to manufacture nickel-based Superalloy materials. The purpose of this research was to find out the effects of variation of nickel composition on physical and mechanical properties of the Superalloy materials and find out the appropriate composition of Superalloy materials as materials for turbine blades. This research used nickel, cobalt, chromium, molybdenum, aluminium, and titanium commercial. The results showed that with more addition of nickel composition, the density and hardness values increased. This research showed that nickel-based Superalloy material 59 wt% was better applied as materials for turbine blades. It is also supported by the results of the test microstructure, where the structure of the sample morphology is more delicate and denser and contains smaller pores. Based on the XRD test results are also shown in the sample has been formed Superalloys phase.
Optimization of Additional Composition Variations ZnO Nanoparticles on The Characteristics of Porous Hydroxypatite as Bone Filler Fardatul Azkiyah; Drs. Djony Izak Rudyardjo, M.Si.; Jan Ady
Indonesian Applied Physics Letters Vol. 2 No. 2 (2021): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iapl.v2i2.31699

Abstract

Research on the synthesis and characterization of porous hydroxyapatite with the addition of ZnO nanoparticles has been carried out through a combination of foam immersion and injection methods. This research was conducted to optimize the previous research by increasing the variation of ZnO composition and adding the injection method to the research process. The materials used in this research include hydroxyapatite nanoparticles, ZnO nanoparticles, Aquades, PVA and polyurethane foam. Manufacturing is done by immersing polyurethane foam into a slurry. Slurry is a mixture of PVA and hydroxyapatite solutions with variations in the addition of ZnO nanoparticles (8 wt%, 10 wt%, 12 wt%, and 14 wt%). Then inject the remaining slurry into the foam. After that the sample was dried and heated at a temperature of 650ºC to remove foam and PVA, then the sample was sintered at a temperature of 1200ºC for 3 hours. Based on SEM analysis, porosity test, and compressive strength test, the best results were shown by sample IV because it had a pore diameter of 142.9 – 371.4 m with a porosity of 69.983%, a compressive strength value of 1.8653 MPa and non-toxic. The best results have not met the standard for bone filler application. In further research, improvements need to be made by using other additives such as ZrO2, so that it can improve the mechanical properties of porous hydroxyapatite to meet standard bone filler applications.
PERILAKU KOROSI MATERIAL GELAS METALIK BERBASIS ZIRKONIUM UNTUK MATERIAL IMPLAN Djony Izak Rudyardjo
JURNAL ILMIAH SAINS Volume 11 Nomor 2, Oktober 2011
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (323.786 KB) | DOI: 10.35799/jis.11.2.2011.213

Abstract

PERILAKU KOROSI MATERIAL GELAS METALIK BERBASIS ZIRKONIUM UNTUK MATERIAL IMPLAN Djony Izak Rudyardjo1) 1)Departemen Fisika FST Universitas Airlangga, Kampus C Jl. Mulyorejo, Surabaya ABSTRAK Penelitian ini bertujuan untuk mempelajari perilaku korosi, pengaruh variasi komposisi paduan dan variasi konsentrasi larutan NaCl terhadap nilai laju korosi material gelas metalik yang berbasis zirkonium, dan untuk mengetahui potensi material gelas metalik berbasis zirkonium untuk material implan. Hasil uji XRD menunjukkan pola difraksi hanya merupakan cacah latar. Selanjutnya, laju korosi 0,36% NaCl pada variasi campuran elemen Zr67Cu33, Zr69.5Cu12Ni11Al7.5, Zr70Ni15Al15 dan   Zr67,6Cu11,8Ni10,8Al7,8Si2 berturut-turut adalah  17,7324 mpy; 13,5916 mpy; 7,1273 mpy da 5.8582 mpy.   Variasi campuran elemen mempengaruhi laju korosi dan Zr67,6Cu11,8Ni10,8Al7,8Si2 mempunyai daya  tahan korosi yang baik, karena adanya elemen Ni dan Si yang membuat reaksi korosi menjadi lambat. Hasil uji korosi pada sampel Zr69.5Cu12Ni11Al7.5 dengan variasi konsentrasi larutan NaCl 0,355%; 0,362%; 0,369% dan 0,376%   berturut-turut adalah 12,0732 mpy; 13,5916 mpy; 19,6227 mpy dan  28.1623 mpy.  Hasilnya menunjukkan laju korosi cenderung meningkat dengan peningkatan konsentrasi larutan NaCl. Dari penelitian ini dapat disimpulkan bahwa zirkonium berbasis gelas metalik mempunyai potensi untuk material implan. Hal ini sesuai dengan salah satu syarat untuk material implan, yaitu harus mempunyai daya tahan korosi yang tinggi, sehingga kinerjanya sebagai material implan tidak membahayakan tubuh. Kata kunci:  gelas metalik, korosi, material implan   THE BEHAVIOR OF ZIRCONIUM-BASED METALLIC GLASSES FOR IMPLANT MATERIALSABSTRACT The aim of this research was to study the corrosion behavior, the effects of composition and concentration variation of NaCl solution on corrosion rate of zirconium-based metallic glasses, and to ecaluate the potential of this glasses for implant material. The result of XRD test showed that the diffraction pattern was only the back ground.  Furthermore, corrosion rates of alloy elements Zr67Cu33, Zr69.5Cu12Ni11Al7.5, Zr70Ni15Al15 and Zr67,6Cu11,8Ni10,8Al7,8Si2 in 0,36% NaCl were 17,7324 mpy; 13,5916 mpy; 7,1273 mpy and 5.8582 mpy, respectively.  Variation of alloy element affected the corrosion rate.  Zr67,6Cu11,8Ni10,8Al7,8Si2 had the best corrosion resistant because of  the present of Ni and Si, so that the corrosion reaction occured slower. The corrosion rate of corrosion test on Zr69.5Cu12Ni11Al7.5 in 0,355, 0,362, 0,369 and 0,376% NaCl were  12,0732 mpy, 13,5916 mpy, 19,6227 mpy and 28’1623 mpy respectively.  The results indicated that increasing the concentration of  NaCl solution tended to increase the corrosion rate.  It could be concluded that zirconium-based metallic glasses has potential for implant material.  As this material  had the higest, it was suitable for implant material  and it did not andanger our body due to corrosion process. Keywords: metallic glasses, corrosion, implant materials
PENGARUH PENAMBAHAN PLASTICIER GLISEROL TERHADAP KARAKTERISTIK HIDROGEL KITOSAN-GLUTARALDEHID UNTUK APLIKASI PENUTUP LUKA Djony Izak Rudyardjo
JURNAL ILMIAH SAINS Volume 14 Nomor 1, April 2014
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (431.249 KB) | DOI: 10.35799/jis.14.1.2014.4883

Abstract

PENGARUH PENAMBAHAN PLASTICIER GLISEROL TERHADAP KARAKTERISTIK HIDROGEL KITOSAN-GLUTARALDEHID UNTUK APLIKASI PENUTUP LUKA ABSTRAK Telah dilakukan penelitian untuk mengetahui pengaruh penambahan plasticizer gliserol terhadap karakteristik hidrogel kitosan-glutaraldehid untuk aplikasi penutup luka. Penambahan gliserol bertujuan agar hidrogel kitosan-glutaraldehid lebih fleksibel dan memiliki sifat mekanik yang baik sehingga dapat diaplikasikan sebagai penutup luka sesuai dengan standar yang ada. Pembuatan hidrogel dilakukan dengan cara mencampurkan kitosan yang dilarutkan dalam 1% asam asetat dengan 1% larutan glutaraldehid pada perbandingan 50 : 3 (v/v) dan ditambahkan gliserol dengan variasi volume 1 ml – 4 ml. Konsentrasi gliserol yang digunakan tidak lebih dari 2%. Berdasarkan penelitian yang telah dilakukan, penambahan gliserol menyebabkan ketebalan, kuat tarik, dan kemampuan mengabsorbsi cairan hidrogel menurun; elongasi dan ketahanan terhadap air  hidrogel meningkat; serta struktur hidrogel menjadi lebih halus. Berdasarkan hasil uji sifat mekanik, hasil terbaik ditunjukkan oleh hidrogel kitosan-glutaraldehid-gliserol dengan penambahan gliserol 2% sebanyak 2 ml, yang memiliki nilai kuat tarik sebesar 14,34 ± 1,90 MPa dan elongasi sebesar 2,40 ± 0,91% yang memenuhi standar sifat mekanik kulit manusia. Struktur permukaan hidrogel tersebut halus, homogen, memiliki ketahanan terhadap air sebesar 24,78 ± 6,57% serta mampu mengabsorbsi cairan lebih dari 99,9% yaitu sebesar 149,65 ± 22,46% yang merupakan karakteristik penting hidrogel. Jadi, dapat disimpulkan bahwa hidrogel kitosan-glutaraldehid-gliserol dengan penambahan gliserol 2% sebanyak 2 ml dapat diaplikasikan sebagai penutup luka. Kata kunci: Glutaraldehid, Gliserol, Hidrogel, Kitosan, Penutup Luka, Plasticizer   THE EFFECT OF ADDITION GLYCEROL AS PLASTICIER TO THE CHARACTERISTICS OF CHITOSAN-GLUTARALDEHYDE HIDROGEL FOR WOUND DRESSING APPLICATION ABSTRACT The research had been done to determine the effect of addition glycerol as plasticizer to the characteristics of chitosan-glutaraldehyde hydrogel for wound dressing application. The addition of glycerol was served to increase flexibility and improve the mechanical properties of chitosan-glutaraldehyde hydrogel that can be applied as a wound dressing accordance with existing standards. Preparation of hydrogel was made by mixing chitosan dissolved in 1% acetic acid with 1% glutaraldehyde solution with ratio 50 : 3 (v/v) and added by glycerol with variation of 1 ml - 4 ml. The glycerol concentration used no more than 2%. Based on the research that had been done, the addition of glycerol caused thickness, tensile strength, and the absorption ability of hydrogel was decreased; elongation and water resistance of hydrogel increased; and the surface structure of hydrogel is more smooth. Based on the result of mechanical properties, the best characteristics of chitosan-glutaraldehyde-glycerol hydrogel is shown with the addition of 2 ml glycerol 2% composition which has a value of tensile strength of 14,34 ± 1,90 MPa and elongation at 2,40 ± 0,91 % that meet the standards of the mechanical properties of human skin. The structure of that hydrogel surface is smooth, homogeneous, has a water resistance of 24,78 ± 6,57%, and is able to absorb liquid more than 99,9% in the amount of 149,65 ± 22,46 % which is an important characteristic of the hydrogel. So, the chitosan-glutaraldehyde-glycerol hydrogel with the addition of 2 ml glycerol 2% can be applied as a wound dressing. Keywords : Chitosan, Glutaraldehyde, Glyserol, Hydrogel, Plasticizer, Wound Dressing
Effect of Nitrogen-Based Ion Implantation on The Characteristics of 316L Stainless Steel for Implant Materials Drs. Djony Izak Rudyardjo, M.Si.; Firman Maulana Ikhsan; Adri Supardi
Indonesian Applied Physics Letters Vol. 3 No. 2 (2022): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iapl.v3i2.40951

Abstract

The effect of nitrogen-based ion implantation on the characteristics of 316l stainless steel for implant materials has been performed. This study aims to determine the effect of variations in implantation energy on the characteristics of the surface mechanical properties, density, and corrosion resistance of 316L stainless steel. The 316L stainless steel plate was implanted with nitrogen ions with an optimum dose of 5 x 1016 ions/cm2 for various implantation energies of 70, 75, 80, 85, and 90 keV. The implanted samples were then characterized by density, hardness, corrosion resistance, and microstructure tests using SEM-EDX. The test results showed an increase in hardness and corrosion resistance in pieces implanted with nitrogen ions and reached the optimum point at an implantation energy of 80 keV. This was also supported by the results of the SEM-EDX analysis, which showed an addition of nitrogen content from the maximum limit of the ASTM 2000 standard for 316L stainless steel of 0.1% to 2.2%. Whereas in the density test, the density of the material tends to be constant at the energy variations carried out but has increased after implantation.
Belajar Fisika Menyenangkan Melalui Diseminasi Material Medis Pada Guru Sekolah Menengah Atas di Kabupaten Trenggalek - Siswanto; Djony Izak Rudyardjo; Jan Ady; - Aminatun; Dyah Hikmawati; Adri Supardi; Prihartini Widiyanti
Prosiding Seminar Nasional Unimus Vol 5 (2022): Inovasi Riset dan Pengabdian Masyarakat Guna Menunjang Pencapaian Sustainable Developm
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Fisika merupakan salah satu pelajaran yang dianggap sulit bagi sebagian besar siswa SMA. Ilmutersebut dianggap abstrak dan hanya dipenuhi rumus matematika yang kurang jelas kontribusinyadalam kehidupan sehari-hari. Selain itu fisika kurang memberikan prospek pekerjaan yangmenjanjikan sehingga ketertarikan siswa menekuni sains tersebut lebih rendah dibandingkan ilmuyang lainnya. Salah satu penyebab mindset ini adalah faktor guru yang belum mengetahui kontribusifisika dalam segala aspek kehidupan  termasuk dalam bidang medis. Oleh sebab itu kegiatan penmasditujukan bagi guru fisika SMA di kecamatan Kampak Trenggalek dengan tujuan diseminasi hasilpenelitian material medis untuk peningkatan pengetahuannya agar dapat diterapkan ke prosesbelajar mengajar yang menyenangkan. Metode yang digunakan untuk kegiatan ini adalah ceramahdan demo pembuatan material medis dengan memanfaatkan sumber daya alam lokal. Hasil kegiatanmenunjukkan bahwa seluruh peserta belum mengetahui pentingnya fisika dalam mendesainmaterial medis baik untuk jaringan lunak maupun jaringan keras. Perlu dilakukan kegiatan penmasini secara rutin di kabupaten Trenggalek agar guru dapat menghayati secara baik untuk pengajaranfisika yang menyenangkan.Kata Kunci : fisika, guru SMA, diseminasi, material medis , menyenangkan