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Clinical Characteristics of Hospitalized Individuals Dying with COVID-19 in Ulin Regional Hospital Banjarmasin Haryati Haryati; Mohamad Isa; Ali Assagaf; Ira Nurrasyidah; Erna Kusumawardhani
Jurnal Respirasi Vol. 7 No. 1 (2021): January 2021
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (327.938 KB) | DOI: 10.20473/jr.v7-I.1.2021.1-7

Abstract

Background: Corona Virus Disease (COVID-19) has become a global pandemic and has spread to more than 200 countries including Indonesia. South Kalimantan is one of the provinces in Indonesia that has a high COVID-19 mortality rate (case fatality rate 4.1%). Information about characteristic of mortality patients with SARS-CoV-2 infection in Indonesia was limited. The objective of this study to describe clinical characteristics of COVID-19-confirmed deaths at Ulin Regional Hospital Banjarmasin, as a referral hospital in South KalimantanMethods: Medical records of 108 hospitalized patients dying with COVID-19 between March until August 2020 were collected. The recorded information included gender, age, onset and severity of disease, comorbidities, symptoms, signs, and laboratory findingsResults: The 108 confirmed cases of COVID-19 deaths were mostly male (73.1%) aged <65 years old (85.2%). About 84% of the cases had at least one comorbidity or more, like hypertension (44.4%), obesity (38%), and diabetes mellitus (32.4%). Common early symptoms were fever (91.7%) and shortness of breath (89.8%). Laboratory findings included lympocytopenia and eosinophilopenia (80.6% and 72.2%), increased neutrophil lymphocyte ratio (NLR; 86.1%), decreased absolute lymphocyte count (ALC; 72.2%), and hyponatremia (55.6%). Elevated C-reactive protein (CRP; 92.6%), lactate dehydrogenase (LDH; 91.7%), serum glutamic oxaloacetic transaminases (SGOT; 82.4%), and creatinine levels (57.4%). The majority of non survivors were severe-critical stage with severe acute respiratory distress syndrome (ARDS).Conclusion: In this depictive study, patients with comorbidities and severe-critical stage are at risk of death. Laboratory abnormalities were common in non survivors. Shortness of breath may indicate poor prognosis of COVID-19.
Nutritional Status of Hospitalized Tuberculosis Patients in South Kalimantan: A Cross-Sectional Study Mohamad Isa; Ira Nurrasyidah; Elok Hikmatun Nikmah; Desi Rahmawaty; Ali Assagaf; Haryati Haryati; Erna Kusumawardhani
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 22, No 2 (2022): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v22i2.15021

Abstract

The burden of tuberculosis (TB) infection is significant in Indonesia. There is likely a substantial link between TB and malnutrition. Anemia, which is linked to TB patient outcomes and length of hospital stay, is another issue that might aggravate the disease. This study aims to identify how common undernutrition and anemia are among tuberculosis patients at the Ulin Regional Hospital in Banjarmasin. A cross-sectional observational study was conducted using medical record data from 31 hospitalized tuberculosis patients from September to December 2021. Data of weight, height, body mass index (BMI), Hemoglobin (Hb) and blood albumin level at admission were analyzed. The result showed that tuberculosis cases were mostly found in males (61.3%) aged 20-60 years (83.9%). There were 42% of patients with undernutrition (BMI 18.5), 93.5% with anemia, and 71% with hypoalbuminemia. Rifampicin resistance was found in 38.7% of all patients, with 58.3% malnutrition, 100% anemia, and 50% hypoalbuminemia. Thus, there was a possible link between tuberculosis and undernutrition condition. Screening, early diagnosis, and treatment for undernutrition, anemia, and hypoalbuminemia should be encouraged in patients with tuberculosis, whether they are susceptible or resistant to rifampicin, to lower the burden of the disease.
Clinical and Laboratory Features of COVID-19 in Ulin Referral Hospital of South Kalimantan: Predictors of Clinical Outcome Haryati Haryati; Mohamad Isa; Ali Assagaf; Ira Nurrasyidah; Erna Kusumawardhani; Eko Suhartono; Fidya Rahmadhany Arganita
Journal of Tropical Life Science Vol. 11 No. 3 (2021)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.11.03.06

Abstract

Corona Virus Disease (COVID-19) is becoming a global pandemic. Indonesia, especially South Kalimantan had recorded increasing cases with a high fatality rate of 3.7%. Information about factors related to outcomes based on clinical and laboratory features in Indonesia is still limited. Identification of the risk is crucial to determine optimal management and reducing mortality. This retrospective study enrolled 455 adults COVID-19 patients, and data were extracted from medical records of Ulin General Hospital Banjarmasin. The latter is COVID-19 referral hospital in South Kalimantan between March-November 2020. Demographic data, comorbidities, and laboratory were all collected. Data were compared between survivors and non-survivors. Fisher’s exact test and chi-square were used to compare categorical variables. The Mann_Whitney U test was used to compare continuous variables. Analysis was continued by multivariate logistic regression then receiver operating characteristic (ROC) curve to determine cut-off value. The multivariate analysis showed that number of comorbidities [odds ratio (OR) 1,339 (95% confidence interval (CI): 1,064-1,685, P = 0,013) was a significant risk factor to the outcome. In laboratory, lactate dehydrogenase (LDH) [OR: 1.001, 95% CI: 1,000-1.002, P = 0.001], Ferritin (OR 1.000, CI: 1,000-1.001, P = 0.013), APTT (OR: 1.045, CI: 1.010-1.082, P = 0.012), and D-dimer (OR: 1.188, CI: 1.064 - 1.327, P = 0.002) were significant predictor factors but only LDH, ferritin, and D- dimer were obtained good AUC 0.731, 0.715, and 0.705, respectively. The cut of the value of LDH was 656.5 U/L, ferritin was 672.18 ng/ml, and D-dimer was 2.28 mg/L. Sensitivity and specificity were 66.7% and 68,0% for LDH, 83,2% and 56,3% for ferritin, and 62,8 and 70,8% for D-dimer. From this research, we revealed that the number of comorbidities was a risk factor for death. Elevated LDH, ferritin, and D-dimer could be good predictive factors for poor outcomes, thereby considering the accelerating management of COVID-19 patients.
Clinical Characteristic of Different SARS-CoV-2 Variants in South Kalimantan, Indonesia: A Case Study Haryati Haryati; Desi Rahmawaty; Mohamad Isa; Ali Assagaf; Ira Nurrasyidah; Erna Kusumawardhani
Althea Medical Journal Vol 10, No 1 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v10n1.2810

Abstract

Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has undergone various mutations of Corona Virus Disease 2019 (COVID-19). The World Health Organization (WHO) has designated B.1.617.2 (Delta) and B.1.1.529 (Omicron) as variants of concern (VOC). Since clinical features and epidemiological characteristics of patients infected with SARS-CoV-2 variants remain largely unknown, especially in Indonesia, this study aimed to identify the clinical characteristics of COVID-19 patients from South Kalimantan, Indonesia.Methods: Data from medical records of COVID-19 patients at Ulin General Hospital Banjarmasin from June 2021 to February 2022 were randomly extracted, containing demographic data, comorbidities, and laboratory data, as well as the type of virus. Results: In total, 32 patients were included, 9 were infected with delta, 14 with probable omicrons, and 9 with non-VOC. Patients in the probable Omicron group were significantly older than other groups (median age 64 years old, range 54–73 years; p=0.049), had hypertension as the dominant comorbidity (85.7%; p=0.039), the onset appeared slightly earlier (median 3 days; range 2-3 days, p=0.062), with no anosmia symptom (p=0.006). Critical illness predominated and mostly survived in all variants but was not statistically significant (p=0.590 and 0.726, respectively). The three variants showed similarities in laboratory findings; hence, statistical analysis suggested that the leucocytes differed significantly (p=0.020).Conclusions: Patients with the likely Omicron variant are much older, have hypertension as their main comorbidity, do not have any symptoms of anosmia, and have higher leukocyte counts compared to other variants.
PKM Pendidikan Gizi “Isi Piringku” Pemberian Makanan Tambahan Lokal Pada Ibu Hamil Dengan Kekurangan Energi Kronik Devi Rahma Yanti; Mohamad Isa; Fitri Ayatul Azlina
Jurnal Pengabdian ILUNG (Inovasi Lahan Basah Unggul) Vol 3, No 1 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ilung.v3i1.9392

Abstract

Suatu kondisi dimana tidak tercukupinya energi seorang ibu hamil untuk kebutiuhannya dan janinnya karena asupan yang kurang dalam jangka waktu yang lama, inilah yang disebut dengan kekurangan energi kronis (KEK). Ibu hamil dengan masalah gizi dan kesehatan berdampak pada kesehatan dan keselamatan ibu dan bayi serta kualitas bayi yang dilahirkan. Berdasarkan studi epidemiologi, bayi BBLR mempunyai risiko kematian 20 kali lipat lebih besar di bandingkan dengan bayi yang lahir dengan berat badan normal.Perlu upaya yang komprehensif untuk menyelesaikan pemenuhan kebutuhan gizi yang optimal pada ibu hamil, diantaranya pemanfaatan bahan lokal disertai Pendidikan gizi bagi ibu hamil dan balita. Kementerian Kesehatan RI pada tahun 2018 telah menyusun Petunjuk Teknis Panduan Pengajaran Diit Dengan Pemanfaatan Bahan Lokal. Pengajaran dengan metode mencontohkan tentang diit ibu hamil merupakan suatu proses pemindahan informasi tentang nutrisi yang berguna bagi ibu hamil dengan mengedepankan prinsif lengkap dan sempurna. Metode pengajaran menggunakan alat peraga yang digunakan sehari-hari oleh ibu dan aktivitas yang sehari-hari dilaksanakan oleh ibu-ibu. Pendidikan gizi “Isi Piringku” Pemberian makanan Tambahan Lokal dilaksanakan dikegiatan Pengabdian Masyarakat, sinergi antara Universitas Lambung Mangkurat, Puskesmas, PKK Desa/ Kecamatan, dengan target sasaran Ibu Hamil dengan KEK. Pengabdian Masyarakat ini dilaksanakan sebagai upaya meningkatkan pengetahuanibu hamil tentang asupan gizi pada ibu hamil dengan menggunakan bahan lokal yang dimiliki oleh wilayah Kecamatann Karang Intan.Kata kunci: Edukasi; Kekurangan Energi Kronik; ibu hamil
Pendidikan Kesehatan Penatalaksanaan Tuberkolosis Dengan Diabetes Melitus Pada Kader Tuberkolosis Di Puskesmas (PKM) Karang 2 Mohamad Isa; Devi Rahma Yanti; Noorhidayah Noorhidayah; Selvia P.Y
Jurnal Pengabdian ILUNG (Inovasi Lahan Basah Unggul) Vol 3, No 2 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ilung.v3i2.10365

Abstract

Beban penyakit TB menjadi semakin berat dengan meningkatnya kasus diabetes mellitus (DM). Seseorang yang terdiagnosa DM memiliki resiko terinfeksi TB sebesar 3,11 kali. Penatalaksanaan pengobatan TB-DM lebih sulit karena interaksi obat anti-TB (OAT)-obat antidiabetes (OAD) dan efek samping obat.  Pendekatan yang dilakukan diantaranya adalah dengan memberikan  Pendidikan Kesehatan Penatalaksanaan tentang TB dengan DM pada Kader TB sebagai upaya preventif bagi seseorang untuk terhindar dari TB atau DM. Pendidikan Kesehatan merupakan  kegiatan yang memberikan edukasi dengan metode ceramah dan diskusi menggunakan PPT dan leaflet. Selain itu, tim menggunakan kuesioner yang berisi karakteristik responden dan motivasi kerja. Pada kegiatan ini kader yang akan diberikan Pendidikan Kesehatan 19 kader dari 13 desa  wilayah kerja PKM Karang Intan 2. Evaluasi peserta dilakukan sebelum dan sesudah penyuluhan dengan sistem tanya jawab dan diskusi. Dari hasil pendidikan kesehatan, didapatkan sebanyak 70% dari responden mampu menjawab evaluasi dari tim penyuluh. Selain itu, hasil kuesioner didapatkan mayoritas kader TB mempunyai motivasi kerja tinggi yaitu 52,6%, sementara motivasi kerja rendah sebesar 47,4%. Kader TB yang memiliki pengetahuan baik dan motivasi kerja yang tinggi lebih banyak, diharapkan hal ini  terkait pelaksanaan tugasnya semakin besar usaha dalam penemuan kasus TB BTA (+).