Article Per Year (5 Year)
p-Index From 2019 - 2024
0.23
P-Index
This Author published in this journals
All Journal Jurnal Pendidikan Kimia (JPKim)
Fauzan Amin
Sekolah Tinggi Analis Kimia Cilegon, Cilegon, Banten, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Education Environmental Science

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Synthesis and characterization of capsule shells non gelatin grass jelly leaves-seaweed as drug delivery system material Micha Mahardika; Fauzan Amin; Ika Agustia Umami; Boima Situmeang; Agus Malik Ibrahim
Jurnal Pendidikan Kimia (JPKim) Vol 13, No 1 (2021): April
Publisher : Pascasarjana Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (395.857 KB) | DOI: 10.24114/jpkim.v13i1.24138

Abstract

Drug delivery system is a system that describes the journey of a drug to its target location.  The main component of the drug delivery system is gelatin. The leaves of grass jelly-seaweed are needed as a raw material for gelatin. The main component of gelling agents in grass jelly leaves and seaweed is a low-methoxy pectin polysaccharide. Pectin from previous study is used as a synthesis material for hard capsule shells with the addition of other ingredients, which are Na-CMC, sorbitol, and water. The characterization results of capsule shells with variations in the composition of grass jelly-seaweed leaves 0: 4, 1: 3, 2: 2, 3: 1, and 4: 0 (A, B, C, D and E) have a disolving time of 12 minutes 45 seconds; 15 minutes 53 seconds; 23 minutes 10 seconds; 15 minutes 35 seconds and 18 minutes 12 seconds. The swelling degree test each of 200%;  266,7%;  303.3%;  586.7% and 643.3%. Furthermore, the shells of grass jelly-seaweed leaf capsules were tested for their material performance in the cefadroxyl disolving test with variations in sampling time of 10, 20, and 30 minutes.Keywords: Cefadroxyl, Drug delivery system, Green grass jelly leaves, Non-gelatin capsules, Seaweed
Co-Authors Boima Ramses Situmeang Ibrahim, Agus Malik Ika Agustia Umami Micha Mahardika